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Liquid Calcium & Magnesium

4.8
★ ★ ★ ★ ★
(379 ratings)
Calcium 600 mg
Magnesium 300 mg
Product Image
Score79
Good value and substantial mineral amounts are offset by basic carbonate and oxide forms with greater digestive trade-offs.
How scoring works
Softgel
Quantity:100 Softgel(s) • (50 servings)
Goals:
Bone Health
General Health

Score 79

Good value and substantial mineral amounts are offset by basic carbonate and oxide forms with greater digestive trade-offs.
How scoring works
$8.99($0.17 per serving)
iHerb
$ 8.99
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Analysis

Six hundred milligrams of calcium and 300 mg of magnesium can materially contribute to daily mineral intake. Two softgels are easy to use, and the serving cost is favorable.

Both minerals rely on basic forms: calcium carbonate benefits from being taken with food, while magnesium oxide is poorly absorbed relative to citrate or glycinate. The formula does not include vitamin D.

The large mineral amounts may suit a clear dietary gap but are not ideal for everyone at once. Constipation from calcium carbonate or loose stools from magnesium oxide may determine practical tolerance.

Who is it for
  • Adults seeking inexpensive calcium and magnesium
  • People who prefer softgels to tablets
Best for
  • Filling larger mineral gaps
  • Budget-focused mineral supplementation

Pros

  • Provides substantial calcium and magnesium
  • Simple two-softgel serving
  • Strong value per serving

Cons

  • Uses calcium carbonate
  • Uses magnesium oxide
  • Does not include vitamin D

Warnings

  • Magnesium oxide may cause diarrhea or abdominal cramping
  • Calcium carbonate may cause constipation and is best taken with food
  • Separate calcium from thyroid hormone, bisphosphonates, and some antibiotics because it can reduce absorption

Nutrient quality

78 High impact

Calcium carbonate and magnesium oxide are inexpensive forms with weaker absorption than citrate or glycinate, and the 600 mg calcium and 300 mg magnesium amounts are substantial, though calcium may be better divided. The calcium amount is slightly above the most efficient single dose but is not unusually aggressive, while calcium and magnesium form a coherent mineral-support combination without mismatched actives.

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Ingredient transparency

84 Highest impact

The listed active nutrients have specific amounts, and no proprietary blend hides the amount of a listed core mineral. Serving count is supplied, but complete daily-use directions are not provided, while inactive ingredients and excipients are not included in the supplied label details.

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Customer satisfaction

71 High impact

The supplied average rating is strong, and the limited review count reduces confidence in the average rating. Specific review themes are unavailable, so repeated negatives and real-world fit remain uncertain.

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Value for money

83 Highest impact

Mixed mineral forms and dosing trade-offs weaken formula value, and the very low serving cost provides excellent practical value. The listed formula is focused and does not appear padded with low-value active ingredients, while the product is reasonably competitive but lacks a clear quality or value advantage.

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Report analysis

Goals

Bone Health
Impact
High effect
B+ Goal FitC+ Strength of SupportC CoverageB Formula Quality
Magnesium · 300 mgCalcium · 600 mg

Calcium and magnesium provide two important mineral building blocks at clearly disclosed amounts. The calcium serving is practical, but carbonate and oxide generally depend more on digestion or offer weaker absorption than preferred forms.

The paired minerals give broader support than a single-mineral product, yet vitamins D and K and protein-matrix nutrients are absent. Taking calcium carbonate with food may improve practical absorption for people with adequate stomach acid.

Study evidence
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
General Health
Impact
High effect
A Goal FitD+ Strength of SupportC- CoverageB+ Formula Quality
Magnesium · 300 mg

Magnesium and calcium address muscle, nerve, and skeletal functions that matter to foundational health. Their amounts are clearly stated, but magnesium oxide and calcium carbonate offer limited formulation quality for systemic mineral support.

The two-mineral pairing is coherent and avoids an excessive calcium-to-magnesium ratio. Weak absorption and the absence of supportive nutrients such as vitamin D keep the formula from providing strong depth.

Study evidence
Magnesium Supportive 114 studies
Energy
Impact
Moderate effect
C+ Goal FitC Strength of SupportD+ CoverageB+ Formula Quality
Magnesium · 300 mg

A useful magnesium amount supports ATP-related reactions, with calcium adding general mineral coverage. The softgel provides both minerals in a simple serving.

Magnesium oxide and calcium carbonate limit absorption quality, and the pairing is more aligned with bone support than energy. Noticeable fatigue benefits are most plausible when low mineral intake is present.

Study evidence
Magnesium Supportive 4 studies
Digestive Health
Impact
Moderate effect
B- Goal FitC Strength of SupportD- CoverageC+ Formula Quality
Magnesium · 300 mg

Magnesium can support bowel motility and soften stool, but this formula uses oxide rather than the better-targeted citrate form. Calcium carbonate may also work against regularity in people who find calcium constipating.

The elemental amounts are clear, while both mineral forms offer limited absorption. The magnesium amount may still cause loose stools or cramping in sensitive users because unabsorbed magnesium draws water into the bowel.

Study evidence
Magnesium Supportive 50 studies
Heart Health
Impact
Moderate effect
C+ Goal FitC Strength of SupportD CoverageC Formula Quality
Magnesium · 300 mg

Magnesium supports heart rhythm and vascular tone, but the formula is dominated by calcium and uses magnesium oxide. The 300 mg magnesium amount is meaningful on paper, although absorption and digestive tolerance are concerns.

The product is more aligned with general bone-mineral nutrition than broad cardiovascular support. People with impaired kidney function need particular care with substantial supplemental magnesium and calcium because these minerals can accumulate.

Study evidence
Magnesium Supportive 158 studies
Cardiovascular Support
Impact
Moderate effect
C Goal FitD+ Strength of SupportD CoverageC+ Formula Quality
Magnesium · 300 mg

Magnesium provides relevant support for vascular relaxation and normal heart rhythm. Calcium contributes to muscle signaling, but the pair does not address lipids, endothelial antioxidants, or cardiac energy.

The 300 mg magnesium amount is meaningful and the two-to-one calcium balance is clearly disclosed. Magnesium oxide and calcium carbonate are basic forms with limited absorption, which weakens the practical value of the listed doses.

Study evidence
Magnesium Supportive 123 studies
Stress Relief
Impact
Moderate effect
C Goal FitC- Strength of SupportD CoverageC- Formula Quality
Magnesium · 300 mg

The blend includes magnesium, but the oxide form limits absorption and stress-specific value. Calcium dominates the formula without adding a comparably direct stress-relief role.

The disclosed 300 mg magnesium amount appears substantial, yet its effective contribution is uncertain. The softgel is therefore better viewed as a general mineral supplement than a targeted stress formula.

Study evidence
Magnesium Supportive 13 studies

Ingredients

IngredientAmount per serving
Calories
20 Calorie(s)
Total Fat
1.5 Gram(s)
Calcium (Calcium Carbonate)
600 mg
Magnesium (Magnesium Oxide)
300 mg
Adults 18–50
Report overview
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Calcium carbonate supplies a full 600 mg serving, but it generally depends more on stomach acid and food than citrate or chelated forms. The elemental calcium amount is clearly stated, and no concerning additives are shown in the supplied facts. Its low cost per serving makes it practical for people comfortable taking it with a meal.

F Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD- Value

Magnesium oxide provides limited absorption despite a useful elemental amount. Calcium is present at a two-to-one balance with magnesium, so it avoids the stated excess-calcium penalty but adds no preferred uptake cofactor. A low serving cost helps, though the basic mineral forms remain the main drawback.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
    van der Schoot A; Creedon A; Whelan K; Dimidi E · Neurogastroenterology and motility · 2023
    Meta-analysis787 participants8 studies pooledDigestive Health forMagnesium
  2. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  3. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  4. Lactobacillus casei rhamnosus Lcr35 in children with chronic constipation.
    Bu LN; Chang MH; Ni YH; Chen HL; Cheng CC · Pediatrics international : official journal of the Japan Pediatric Society · 2007
    Randomized trial45 participantsDigestive Health forMagnesium
  5. Lactobacillus reuteri DSM 17938 and Magnesium Oxide in Children with Functional Chronic Constipation: A Double-Blind and Randomized Clinical Trial.
    Kubota M; Ito K; Tomimoto K; Kanazaki M; Tsukiyama K; Kubota A; Kuroki H; Fujita M; Vandenplas Y · Nutrients · 2020
    Randomized trial60 participantsDigestive Health forMagnesium
  6. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  7. Magnesium-Rich Mineral Water Improves Stool Consistency and Bowel Habits in Healthy Subjects: A Randomized Controlled Trial.
    Yoneda H; Tomita T; Kitano T; Morishita D; Kodani M; Nishii N; Sei H; Eda H; Sato T; Kawai M; Yokoyama Y; Igeta M; Okugawa T; Fukui H; Shinzaki S · Neurogastroenterology and motility · 2026
    Randomized trial40 participantsDigestive Health forMagnesium
  8. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  9. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  10. Effect of the laxative magnesium oxide on gastrointestinal functional recovery in fast-track colonic resection: a double-blind, placebo-controlled randomized study.
    Andersen J; Christensen H; Pachler JH; Hallin M; Thaysen HV; Kehlet H · Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2012
    Randomized trial49 participantsDigestive Health forMagnesium
  11. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  12. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  13. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  14. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  15. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  16. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  17. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  18. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  19. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  20. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  21. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  22. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  23. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  24. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  25. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  26. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  27. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  28. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  29. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  30. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  31. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  32. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  33. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  34. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  35. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  36. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  37. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  38. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  39. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  40. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  41. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  42. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  43. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium