B-12 2500 mcg
21st Century
B-12 2500 mcg
4.7
★ ★ ★ ★ ★
(9255 ratings)
Vitamin B12 2500 mcg
Score 74.0
A high-dose, cost-effective B12 tablet (cyanocobalamin) providing strong support for energy and metabolic functions at an accessible price point.
Quantity: 110 Tablet(s)Servings size: 1 Tablet(s) (110 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
Cognitive Support
Metabolism Boost
leaderboard Score 74.0
A high-dose, cost-effective B12 tablet (cyanocobalamin) providing strong support for energy and metabolic functions at an accessible price point.
insights Analysis
21st Century's B-12 2500 mcg tablet is a standout for its cost-effectiveness, delivering a powerful dose of cyanocobalamin at a fraction of the cost of many alternatives. This product is ideal for individuals who require a higher daily intake of B12 or are looking for a very economical way to maintain their levels. Despite being a traditional tablet (which can have lower bioavailability compared to sublingual or active forms), the sheer quantity of B12 per serving aims to ensure sufficient absorption for most users. Its popularity and high review count attest to its perceived efficacy and affordability among consumers.
- Very high dosage (2500 mcg) for robust B12 supplementation.
- Excellent price per serving, offering great affordability.
- Highly popular with a significant number of positive reviews.
- Simple and convenient tablet form.
- Uses cyanocobalamin, a synthetic form that requires bodily conversion.
- Standard tablet absorption may be less efficient for some individuals compared to sublingual or liquid alternatives.
- Individuals with severely impaired B12 absorption may still benefit more from active or sublingual forms.
$8.99($0.08 per serving)
 iHerb | $ 8.99 | |
 Amazon | $ 17.98 |
bolt Effectiveness for goals
Vitamin B12 is crucial for red blood cell formation, DNA synthesis, and proper neurological function. It helps maintain the health of nerve cells and supports the metabolism of every cell in the human body. Adequate intake is essential for overall health and well-being.
Vitamin B12 is vital for cellular energy production. However, supplementation primarily increases energy in individuals who are deficient in Vitamin B12. For those with adequate levels, there is limited evidence to suggest it provides an additional energy boost.
Vitamin B12 supplementation is highly effective in treating and preventing B12 deficiency. It can reverse many deficiency symptoms, such as anemia and neurological issues, especially when started promptly. The specific form and dosage depend on the individual's condition and the cause of the deficiency.
Vitamin B12 plays an important role in brain health and nerve function. In individuals with a B12 deficiency, supplementation can improve memory and cognitive issues. However, for people with sufficient B12 levels, there is limited evidence that supplements enhance cognitive abilities.
Yes, Vitamin B12 is essential for maintaining the myelin sheath that protects nerves and for synthesizing neurotransmitters. Deficiency can lead to neurological damage, including tingling, numbness, and difficulty with coordination. Supplementation helps prevent or reverse these issues in deficient individuals.
schedule Dosage, timing & forms
The recommended daily allowance (RDA) for adults is 2.4 mcg, but supplemental dosages can vary widely. For addressing deficiencies or maintaining levels in specific populations, daily dosages often range from 250 mcg to 1000 mcg or more. Higher doses are generally well-tolerated due to B12's low toxicity.
Vitamin B12 supplements are commonly available as cyanocobalamin, methylcobalamin, adenosylcobalamin, and hydroxocobalamin. Cyanocobalamin is a synthetic form, while methylcobalamin and adenosylcobalamin are natural, active forms found in the body. The choice of form may depend on individual needs or preferences.
Vitamin B12 is a water-soluble vitamin, meaning that excess amounts are generally excreted in the urine, making toxicity rare. No Upper Tolerable Intake Level (UL) has been established for Vitamin B12 due to its extremely low potential for harm. However, it is always advisable to follow recommended dosages or consult with a healthcare provider for very high doses.
There is no universally 'best' time to take Vitamin B12, as it can be taken effectively at any time of day. Some suggest taking it in the morning on an empty stomach for optimal absorption, while others find taking it with food helps prevent minor stomach upset. Consistency in taking the supplement is generally more important than the specific timing.
Yes, specific populations often have different Vitamin B12 requirements or dosage recommendations. Vegetarians and vegans, for example, typically require supplementation due to the lack of dietary B12 sources. Older adults and individuals with certain gastrointestinal conditions may also need higher doses due to age-related malabsorption or specific medical conditions.
health_and_safety Safety & interactions
Yes, certain medications can interact with Vitamin B12 absorption or metabolism. These include metformin, proton pump inhibitors (PPIs), H2-receptor antagonists, and some antibiotics. Individuals taking such medications should discuss B12 supplementation with their healthcare provider.
Vitamin B12 is generally considered safe, even at higher doses, because it is a water-soluble vitamin. Excess amounts are typically excreted through urine, minimizing accumulation. However, it is always advisable to consult a healthcare professional before starting any new supplement.
Side effects from Vitamin B12 supplementation are rare, especially with oral forms. Mild gastrointestinal upset or skin reactions have been reported in some individuals. Serious adverse effects are highly uncommon.
Vitamin B12 has a low potential for toxicity because it is a water-soluble vitamin. There is no established upper intake level, as excess amounts are generally excreted without adverse effects. However, extremely high doses without medical supervision are not typically recommended.
Adequate Vitamin B12 is crucial for maternal and infant health during pregnancy and breastfeeding. Supplementation is generally considered safe and is often recommended, particularly for individuals with dietary restrictions. Discuss appropriate dosages with a healthcare professional.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B12 | 2500 mcg |
Categories
Vitamin B12 74.0
This Vitamin B12 product is notable for its very high dosage and exceptional affordability, making it a compelling option for those needing significant B12 intake.
Goals
Energy 75.0
The high 2500 mcg dosage of B12 is well-suited to significantly support cellular energy production, helping to effectively combat fatigue and enhance overall vitality for many users.
Brain Health 74.0
With a strong B12 concentration, this supplement provides robust support for nerve function and contributes to the maintenance of healthy brain processes.
Mood Support 74.0
B12 is crucial for neurotransmitter synthesis, and the elevated dose in this product offers enhanced support for mood regulation and emotional balance.
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