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Calcium Plus Magnesium

4.8
★ ★ ★ ★ ★
(443 ratings)
Calcium 500 mg
Magnesium 200 mg
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Score81
Well-chosen calcium citrate and malate plus magnesium aspartate make a strong mineral formula, with pill burden and missing vitamin D as the main limitations.
How scoring works
Capsule
Quantity:180 Capsule(s) • (60 servings)
Goals:
Bone Health
General Health
Energy
Stress Relief
Cardiovascular Support

Score 81

Well-chosen calcium citrate and malate plus magnesium aspartate make a strong mineral formula, with pill burden and missing vitamin D as the main limitations.
How scoring works
$30.36($0.50 per serving)
iHerb
$ 30.36
Daily Vita
$ 30.36
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Analysis

Calcium citrate and malate are useful organic forms that can be taken with or without a large meal. Five hundred milligrams materially supports intake without forcing a very large single calcium dose.

Magnesium aspartate adds 200 mg and keeps the formula free of magnesium oxide. The label clearly states the active forms, although no vitamin D is included to broaden bone support.

Three capsules per serving may be inconvenient for some users, and value is only moderate. The balanced amounts make the product easier to integrate with diet than several higher-dose alternatives.

Who is it for
  • Adults seeking well-formed calcium without carbonate
  • People wanting moderate magnesium alongside calcium
Best for
  • Bone-mineral supplementation
  • Flexible calcium dosing with meals or between meals

Pros

  • Uses calcium citrate and malate
  • Avoids magnesium oxide
  • Provides balanced, meaningful mineral amounts

Cons

  • Requires three capsules per serving
  • Does not include vitamin D
  • Value is only moderate

Warnings

  • Calcium can reduce absorption of thyroid hormone, bisphosphonates, and some antibiotics, so doses should be separated
  • Magnesium may cause loose stools in sensitive users
  • People with impaired kidney function should review supplemental magnesium use with a clinician

Nutrient quality

94 Highest impact

Calcium citrate and malate are well-regarded forms, while magnesium aspartate offers moderate absorption, and the 500 mg calcium and 200 mg magnesium amounts fit practical supplemental ranges. The disclosed amounts show no obvious broad overdosing for typical supplemental use, while calcium and magnesium form a coherent mineral-support combination without mismatched actives.

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Ingredient transparency

73 High impact

Total mineral amounts are shown, but repeated amounts across forms make each form contribution unclear, and no proprietary blend hides the amount of a listed core mineral. Serving count is supplied, but complete daily-use directions are not provided, while inactive ingredients and excipients are not included in the supplied label details.

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Customer satisfaction

72 High impact

The supplied average rating is strong, and moderate review volume provides a reasonable evidence base. Specific review themes are unavailable, so repeated negatives and real-world fit remain uncertain.

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Value for money

82 Highest impact

Favorable mineral forms and useful amounts generally justify the product positioning, and the moderate serving cost is reasonable for the disclosed minerals. The listed formula is focused and does not appear padded with low-value active ingredients, while the formula and serving value compare well with similar mineral products.

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Report analysis

Goals

Bone Health
Impact
Highest effect
A Goal FitA- Strength of SupportC+ CoverageA Formula Quality
Magnesium · 200 mgCalcium · 500 mg

Calcium citrate and malate provide structural mineral, while magnesium aspartate supports bone formation and calcium regulation. Both minerals are supplied in useful amounts and in reasonably absorbable forms.

The formula offers more breadth than a single mineral but still lacks vitamin D, vitamin K, and protein-matrix support. Its simple two-mineral design is coherent and avoids unrelated padding.

Study evidence
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Impact
High effect
B+ Goal FitB Strength of SupportC+ CoverageA Formula Quality
Magnesium · 200 mg

Calcium and magnesium provide focused mineral support for bones, muscles, and normal nerve function. Magnesium aspartate is more credible for systemic use than oxide, and its amount is useful.

The calcium amount is much larger than the magnesium amount, so the formula favors bone-mineral intake over balanced magnesium support. All active amounts and forms are clearly disclosed without decorative blends.

Study evidence
Magnesium Supportive 114 studies
Energy
Impact
High effect
B- Goal FitB Strength of SupportD+ CoverageA Formula Quality
Magnesium · 200 mg

Magnesium is required for ATP-dependent reactions and muscle function, but supplementation chiefly helps energy when intake is inadequate. Its metabolic role is well established, while direct fatigue improvement is less predictable in people without deficiency.

The 200 mg elemental magnesium amount meets the configured minimum for meaningful metabolic support. Magnesium aspartate offers moderate absorption and is clearly quantified, but no premium chelation is verified.

Study evidence
Magnesium Supportive 4 studies
Stress Relief
Impact
High effect
B Goal FitB+ Strength of SupportD+ CoverageB- Formula Quality
Magnesium · 200 mg

A meaningful magnesium amount may support nervous-system regulation when intake is low. Magnesium aspartate offers moderate absorption but is not a premium calming form.

A much larger calcium amount may compete with magnesium absorption and adds no direct stress pathway. The formula remains narrow and is designed more for mineral balance than focused relaxation.

Study evidence
Magnesium Supportive 13 studies
Cardiovascular Support
Impact
High effect
B- Goal FitB- Strength of SupportD CoverageC+ Formula Quality
Magnesium · 200 mg

Magnesium aspartate may support vascular tone and cardiac electrical function. The elemental amount is suitable for general supplementation.

Calcium exceeds magnesium by more than two to one and may compete with absorption. The formula is better aligned with bone minerals than a comprehensive cardiovascular goal.

Study evidence
Magnesium Supportive 123 studies
Impact
Moderate effect
C+ Goal FitC+ Strength of SupportD- CoverageC Formula Quality
Magnesium · 200 mg

Magnesium offers a direct connection to normal rhythm and vascular tone. The stated serving reaches a useful supplemental amount.

Magnesium aspartate is a moderate-quality form, while the much larger calcium load may compete with its use. The focused mineral design is clean but does not address other major heart-health pathways.

Study evidence
Magnesium Supportive 158 studies
Testosterone Support
Impact
Moderate effect
D Goal FitC Strength of SupportF CoverageC+ Formula Quality
Magnesium · 200 mg

Magnesium aspartate supplies a supportive amount for people whose magnesium intake is low. The form should absorb reasonably, although it lacks a verified premium chelation standard.

Calcium dominates the formula and may compete with magnesium absorption when taken together. The narrow mineral design offers limited testosterone support and no vitamin D, zinc, boron, or stress pathway.

Study evidence
Magnesium Disputed 5 studies

Ingredients

IngredientAmount per serving
Calcium (Calcium Citrate, Calcium Malate)
500 mg
Magnesium (Magnesium Aspartate)
200 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

Calcium citrate and malate provide highly bioavailable forms with strong metabolic utility. The 500 mg serving sits in the absorption-efficient target range. No artificial colors, sweeteners, titanium dioxide, or high sugar are disclosed in the supplied data, while the middle-tier serving cost is partly justified by the higher-quality mineral forms.

D Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyD+ Value

Magnesium aspartate offers moderate absorption but lacks a verified premium chelation standard. 200 mg of elemental magnesium is clearly disclosed and falls in the standard supplemental range; calcium exceeds magnesium by more than two to one, which may compete with magnesium absorption. Value is fair, with an effective amount but no premium or patented form to justify the cost.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  2. Magnesium intake from food and supplements is associated with bone mineral density in healthy older white subjects.
    Ryder KM; Shorr RI; Bush AJ; Kritchevsky SB; Harris T; Stone K; Cauley J; Tylavsky FA · Journal of the American Geriatrics Society · 2006
    Cross-sectional study2,038 participantsBone Health forMagnesium
  3. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  4. Magnesium intake, bone mineral density, and fractures: results from the Women's Health Initiative Observational Study.
    Orchard TS; Larson JC; Alghothani N; Bout-Tabaku S; Cauley JA; Chen Z; LaCroix AZ; Wactawski-Wende J; Jackson RD · The American journal of clinical nutrition · 2014
    Cohort study73,684 participantsBone Health forMagnesium
  5. Association between magnesium deficiency scores and hip bone health in adults: a population-based study.
    Li S; Chang W; Wu G; Wang K; Sun X; Sun H; Zhou J · Magnesium research · 2025
    Cross-sectional study13,259 participantsBone Health forMagnesium
  6. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  7. The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
    van der Schoot A; Creedon A; Whelan K; Dimidi E · Neurogastroenterology and motility · 2023
    Meta-analysis787 participants8 studies pooledDigestive Health forMagnesium
  8. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  9. Effect of the laxative magnesium oxide on gastrointestinal functional recovery in fast-track colonic resection: a double-blind, placebo-controlled randomized study.
    Andersen J; Christensen H; Pachler JH; Hallin M; Thaysen HV; Kehlet H · Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2012
    Randomized trial49 participantsDigestive Health forMagnesium
  10. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  11. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  12. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  13. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  14. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  15. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  16. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  17. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  18. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  19. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  20. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  21. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  22. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  23. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  24. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  25. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  26. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  27. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  28. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  29. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  30. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  31. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  32. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  33. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  34. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  35. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  36. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  37. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  38. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  39. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  40. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  41. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  42. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  43. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  44. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium