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EstroSense

Natural Factors WS WomenSense
4.8
★ ★ ★ ★ ★
(17349 ratings)
Rosemary
Lycopene 5 mg
Green Tea 100 mg
Milk Thistle 50 mg
Turmeric 50 mg
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Score81
A focused estrogen-metabolism formula with broad but modest antioxidant support. It is better suited to its hormone-related purpose than skin or cardiovascular goals.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Cardiovascular Support

Score 81

A focused estrogen-metabolism formula with broad but modest antioxidant support. It is better suited to its hormone-related purpose than skin or cardiovascular goals.
How scoring works
$22.37($0.74 per serving)
Vitacost
$ 24.59
iHerb
$ 22.37
Amazon
$ 22.37
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Analysis

The formula centers on 150 mg calcium D-glucarate, 150 mg indole-3-carbinol, and 50 mg DIM. Green tea, turmeric, milk thistle, rosemary, lycopene, and sulforaphane add antioxidant breadth.

Several botanicals name marker compounds without disclosing their concentration, so active potency remains uncertain. Five milligrams of tomato lycopene offers general antioxidant support but does not make the formula skin- or heart-focused.

Two capsules per serving are practical for users specifically seeking estrogen-metabolism support. The hormone-active core may not fit people using hormone therapy or managing hormone-sensitive conditions without tailored guidance.

Who is it for
  • Adults specifically seeking hormone-metabolism support
  • People who value DIM with indole-3-carbinol
  • Users able to review compatibility with hormone treatment
Best for
  • Estrogen-metabolism support
  • Combining DIM with calcium D-glucarate
  • A decaffeinated green-tea component

Pros

  • Coherent hormone-metabolism core
  • Uses decaffeinated green tea
  • Clearly lists each active amount

Cons

  • Botanical standardization is incomplete
  • Lycopene amount is modest
  • Weak fit for dedicated skin or heart support

Warnings

  • DIM and indole-3-carbinol affect estrogen metabolism, so people using hormone therapy or managing hormone-sensitive conditions should obtain individualized guidance.

Nutrient quality

78 High impact

A hormone-metabolism blend combines DIM, indole compounds, green tea, turmeric, and milk thistle. Several amounts are useful but not consistently strong.

Ingredient transparency

85 Highest impact

Active ingredients have stated amounts without a proprietary blend. Several extracts also identify useful forms or standards.

Customer satisfaction

90 Highest impact

The aggregate rating is favorable and is supported by substantial review volume. No specific comments are supplied, so repeated complaints and purpose alignment cannot be confirmed directly.

Value for money

70 High impact

Value is reasonable for the effective doses and ingredient forms. Lightly dosed additions or premium pricing weaken competitiveness.

Report analysis

Goals

Cardiovascular Support
Impact
Moderate effect
C- Goal FitC- Strength of SupportD+ CoverageD+ Formula Quality
Lycopene · 5 mg

Decaffeinated green tea polyphenols and lycopene provide modest support for endothelial antioxidant defenses. Turmeric and rosemary add compatible but secondary antioxidant activity.

No omega-3, magnesium, CoQ10, vasodilator, or meaningful lipid-management active broadens the cardiovascular case. Hormone-metabolism ingredients dominate the formula, making heart support incidental.

Study evidence
Green Tea Supportive 95 studies
Lycopene Supportive 68 studies

Ingredients

IngredientAmount per serving
Calcium-D-Glucarate
150 mg
Indole-3-Carbinol
150 mg
Sunphenon decaffeinated Green Tea extract (Polyphenols)
100 mg
Turmeric extract (Curcuminoids)
50 mg
Milk Thistle extract (Silymarin)
50 mg
Di-Indolylmethane
50 mg
Rosemary extract (Carnosic Acid)
25 mg
Lycopene (Tomato)
5 mg
Sulforaphane (BroccoPhane Broccoli sprout powder)
200 mcg
Gluten Free Vegan Dairy Free Sugar Free Women 18–50 Menopause Vegetarian
Report overview
C Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyC Value

The named active marker improves ingredient detail, but its percentage and the plant part are not stated. The 25 mg amount provides a modest dose in this complex formula. The higher serving cost is partly justified by substantial companion ingredients.

Lycopene (Tomato) · 5 mg OverallScore48
D Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value

Natural tomato sourcing is identified, but the extract has no stated standardization or broader tomato matrix. The dry capsule needs a fat-containing meal, while the lycopene amount is respectable for general antioxidant support. Indole-3-carbinol and DIM alter estrogen metabolism, so the formula may not suit people using hormone therapy without clinical guidance.

F Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyF Value

A decaffeinated extract makes stimulant exposure clear, but the label does not disclose an EGCG amount or qualifying active-marker percentage. Green tea is a minor part of a complex blend without added absorption support. Value for a meaningful EGCG dose cannot be verified.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effectiveness of dietary supplements for skin photoaging in healthy adults: a systematic review and meta-analysis of randomized controlled trials.
    Yang Q; Li H; Zhang H; Ma L; Zhang X; Wu J · Frontiers in medicine · 2025
    Meta-analysis40 studies pooledSkin Health forLycopene
  2. Supplementation with tomato-based products increases lycopene, phytofluene, and phytoene levels in human serum and protects against UV-light-induced erythema.
    Aust O; Stahl W; Sies H; Tronnier H; Heinrich U · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2005
    Randomized trialSkin Health forLycopene
  3. Lycopene not in pill, nor in natura has photoprotective systemic effect.
    Sokoloski L; Borges M; Bagatin E · Archives of dermatological research · 2016
    Randomized trial20 participantsSkin Health forLycopene
  4. Systemic and skin-targeting beneficial effects of lycopene-enriched ice cream: A pilot study.
    Chernyshova MP; Pristenskiy DV; Lozbiakova MV; Chalyk NE; Bandaletova TY; Petyaev IM · Journal of dairy science · 2019
    Randomized trialSkin Health forLycopene
  5. Tomato and lycopene supplementation and cardiovascular risk factors: A systematic review and meta-analysis.
    Cheng HM; Koutsidis G; Lodge JK; Ashor A; Siervo M; Lara J · Atherosclerosis · 2017
    Meta-analysis21 studies pooledCardiovascular Support forLycopene
  6. Effects of lycopene intake on HDL-cholesterol and triglyceride levels: A systematic review with meta-analysis.
    Inoue T; Yoshida K; Sasaki E; Aizawa K; Kamioka H · Journal of food science · 2021
    Meta-analysis854 participants11 studies pooledCardiovascular Support forLycopene
  7. The Effects of Lycopene and Tomato Consumption on Cardiovascular Risk Factors in Adults: A Grade Assessment Systematic Review and Meta-analysis.
    Zamani M; Behmanesh Nia F; Ghaedi K; Mohammadpour S; Amirani N; Goudarzi K; Kolbadi KSH; Ghanavati M; Ashtary-Larky D · Current pharmaceutical design · 2023
    Meta-analysis34 studies pooledCardiovascular Support forLycopene
  8. Lycopene and risk of cardiovascular diseases: A meta-analysis of observational studies.
    Song B; Liu K; Gao Y; Zhao L; Fang H; Li Y; Pei L; Xu Y · Molecular nutrition & food research · 2018
    Meta-analysis14 studies pooledCardiovascular Support forLycopene
  9. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans.
    Nagao T; Hase T; Tokimitsu I · Obesity (Silver Spring, Md.) · 2007
    Randomized trial240 participantsCardiovascular Support forGreen Tea
  10. The effects of green tea supplementation on cardiovascular risk factors: A systematic review and meta-analysis.
    Zamani M; Kelishadi MR; Ashtary-Larky D; Amirani N; Goudarzi K; Torki IA; Bagheri R; Ghanavati M; Asbaghi O · Frontiers in nutrition · 2023
    Meta-analysis55 studies pooledCardiovascular Support forGreen Tea
  11. Effect of Green Tea on Blood Pressure in Healthy Individuals: A Meta-Analysis.
    Yıldırım Ayaz E; Dincer B; Mesci B · Alternative therapies in health and medicine · 2023
    Meta-analysis680 participants9 studies pooledCardiovascular Support forGreen Tea
  12. Effects of green tea on lipid profile in overweight and obese women.
    Li A; Wang Q; Li P; Zhao N; Liang Z · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2024
    Meta-analysis1,818 participants15 studies pooledCardiovascular Support forGreen Tea
  13. Green tea consumption and risk of cardiovascular and ischemic related diseases: A meta-analysis.
    Pang J; Zhang Z; Zheng TZ; Bassig BA; Mao C; Liu X; Zhu Y; Shi K; Ge J; Yang YJ; Dejia-Huang; Bai M; Peng Y · International journal of cardiology · 2016
    Meta-analysis259,267 participants9 studies pooledCardiovascular Support forGreen Tea
  14. Improvement of vascular endothelial function by intake of lycopene-rich tomato juice in healthy adults: a randomized, placebo-controlled, double-blind, parallel-group comparative study.
    Yoshida K; Nakazawa Y; Takahashi S; Suzuki S · Food & function · 2025
    Randomized trial75 participantsCardiovascular Support forLycopene
  15. Lycopene and tomato and risk of cardiovascular diseases: A systematic review and meta-analysis of epidemiological evidence.
    Cheng HM; Koutsidis G; Lodge JK; Ashor AW; Siervo M; Lara J · Critical reviews in food science and nutrition · 2019
    Meta-analysis25 studies pooledCardiovascular Support forLycopene