Name: EstroSense
Brand: Natural Factors WS WomenSense
SKU: 1lAYAgzj
Rating: 477.0 (15004 reviews)

Question 1

How do Di-Indolylmethane (DIM) and Indole-3-Carbinol (I3C) support the body's metabolic processes?

Accepted Answer

DIM and I3C are compounds found in cruciferous vegetables that are known to influence estrogen metabolism. They support the conversion of estrogen into beneficial metabolites, potentially helping to maintain a healthy hormone balance. These compounds are studied for their roles in pathways that process hormones.

Question 2

What is the function of Calcium-D-Glucarate in the body?

Accepted Answer

Calcium-D-Glucarate assists the body's natural detoxification processes, particularly glucuronidation, which helps eliminate toxins and excess hormones. It supports liver function by inhibiting an enzyme called beta-glucuronidase. This action allows for the efficient removal of various substances from the body.

Question 3

How do Milk Thistle extract and Turmeric extract contribute to overall well-being?

Accepted Answer

Milk Thistle, particularly its active compound Silymarin, is recognized for supporting liver health and detoxification pathways. Turmeric extract, with its active Curcuminoids, is well-regarded for its antioxidant and anti-inflammatory properties. Together, they can offer synergistic support for cellular health and detoxification.

Question 4

What role does Sulforaphane from broccoli sprouts play in the body?

Accepted Answer

Sulforaphane is an active compound derived from broccoli sprouts, recognized for its ability to stimulate the body's natural detoxification enzymes. It supports phase II detoxification in the liver, which aids in neutralizing and eliminating various environmental toxins and harmful compounds. This action contributes to cellular protection.

Question 5

What benefits are associated with the polyphenols found in Green Tea extract?

Accepted Answer

Green Tea extract contains polyphenols, such as EGCG, which are powerful antioxidants. These compounds help protect cells from oxidative stress and damage caused by free radicals. They also support various aspects of metabolic health and overall well-being.

Question 6

How might the combination of DIM, I3C, and Calcium-D-Glucarate support hormone balance?

Accepted Answer

DIM and I3C are known to support beneficial estrogen metabolism pathways, while Calcium-D-Glucarate aids in the elimination of excess hormones from the body. This combination can synergistically enhance the body's ability to process and excrete estrogen metabolites. This integrated action helps promote a healthy hormonal environment.

Question 7

What is the function of Lycopene, and where is it commonly found?

Accepted Answer

Lycopene is a potent antioxidant carotenoid primarily found in red and pink fruits and vegetables, such as tomatoes. It is known for its ability to protect cells from oxidative damage. Its antioxidant properties contribute to overall cellular health and can benefit various bodily systems.

Question 8

What benefits are associated with Carnosic Acid from Rosemary extract?

Accepted Answer

Carnosic Acid, a key compound in Rosemary extract, is recognized for its strong antioxidant and anti-inflammatory properties. It helps protect cells from oxidative stress and supports cellular defense mechanisms. This extract can contribute to overall cellular health and vitality.

Question 9

Is it generally recommended to take supplements containing compounds like DIM and I3C with food?

Accepted Answer

Yes, it is often suggested to take supplements containing Di-Indolylmethane (DIM) and Indole-3-Carbinol (I3C) with food. This can help minimize potential digestive discomfort and may aid in the absorption of these compounds. Following product-specific instructions is always best.

Question 10

For optimal utilization, should ingredients such as lycopene and turmeric extract be consumed with food or healthy fats?

Accepted Answer

Lycopene is a fat-soluble compound, and its absorption is significantly enhanced when consumed with dietary fats. Similarly, the curcuminoids in turmeric extract also benefit from being taken with food, especially those containing fats, for improved bioavailability. This helps ensure better uptake by the body.

Question 11

Is there an optimal time of day to take a supplement blend that includes green tea extract and milk thistle?

Accepted Answer

While there's no universally strict optimal time, taking such a blend with a meal can help improve absorption and reduce potential stomach upset. For green tea extract, even decaffeinated forms, some prefer morning or midday. Milk thistle can generally be taken at any time.

Question 12

What are the general recommendations regarding the duration of use for botanical extracts like Indole-3-Carbinol and Calcium-D-Glucarate?

Accepted Answer

The appropriate duration for taking supplements containing these botanical extracts can vary based on individual needs and product instructions. Some compounds may be taken for ongoing support, while others might be recommended for shorter periods. It is always advised to consult the product's specific guidelines or a healthcare professional.

Question 13

If a dose of a daily supplement containing multiple plant extracts is missed, what is the recommended course of action?

Accepted Answer

If a dose is missed, it is generally recommended to take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Question 14

How does the form of an ingredient, such as "BroccoPhane Broccoli sprout powder" versus a standardized extract, affect typical dosage or timing?

Accepted Answer

The form of an ingredient can influence its concentration and how it's standardized, which then dictates the dosage. Powders might contain a broader spectrum of compounds, while extracts are concentrated for specific active components like sulforaphane. However, timing recommendations typically remain general (e.g., with food) regardless of the precise form, focusing more on potential digestive impact or absorption.

Question 15

Are there common considerations for taking supplements containing both Indole-3-Carbinol and Di-Indolylmethane together?

Accepted Answer

Indole-3-Carbinol (I3C) is a precursor to Di-Indolylmethane (DIM) in the body, meaning they are related compounds often found together or sequentially in supplements. When taken together, they are generally formulated to work synergistically. Dosage and timing recommendations would typically be provided for the combined product, often suggesting intake with food.

Question 16

Can the polyphenols from green tea extract influence the absorption or metabolism of other compounds in a multi-ingredient supplement?

Accepted Answer

Green tea polyphenols, such as EGCG, can potentially influence the absorption or metabolism of certain compounds due to their broad biological activity. However, in a multi-ingredient supplement, formulations are generally designed to minimize negative interactions. Taking the supplement with food can also help buffer potential effects.

Question 17

What are the general guidelines for taking a blend of botanical extracts, including Calcium-D-Glucarate and Rosemary extract, concerning meal times?

Accepted Answer

Many botanical extracts, including Calcium-D-Glucarate and Rosemary extract, are generally well-tolerated and can be taken with or without food. However, consuming them with a meal is often recommended as it can help prevent potential stomach upset and support consistent absorption. Always refer to specific product instructions for best results.

Question 18

Is there any advice regarding how frequently to take a supplement that combines various plant-based compounds like those found in broccoli sprouts and turmeric?

Accepted Answer

The frequency for taking a supplement combining plant-based compounds like sulforaphane from broccoli sprouts and curcuminoids from turmeric is typically once or twice daily, as directed by the product label. This dosage schedule is designed to maintain consistent levels of the active ingredients in the body. Always adhere to the recommended serving size and frequency.

Question 19

Are there common side effects associated with the ingredients in this supplement, such as DIM, I3C, or milk thistle?

Accepted Answer

Some individuals may experience mild digestive upset, headaches, or changes in urine color when taking these ingredients. These effects are generally transient and individual responses can vary. Always consult a healthcare professional if side effects persist or are severe.

Question 20

Can ingredients like turmeric extract or green tea extract interact with blood-thinning medications?

Accepted Answer

Turmeric and green tea extracts may possess mild antiplatelet properties. Individuals taking anticoagulant or antiplatelet medications should consult a healthcare professional to assess potential additive effects or interactions. Medical guidance is important to ensure safety.

Question 21

Do ingredients such as milk thistle, turmeric, and green tea extract affect liver enzymes or medication metabolism?

Accepted Answer

Several ingredients, including milk thistle and turmeric, can influence liver detoxification enzymes (cytochrome P450 system). This interaction might alter the metabolism of certain prescription medications, potentially impacting their efficacy or safety. It is advisable to discuss this with a doctor if you are taking any prescription drugs.

Question 22

Is it safe to use supplements containing DIM and Indole-3-Carbinol if I am on hormonal birth control or have a hormone-sensitive condition?

Accepted Answer

DIM and Indole-3-Carbinol can influence estrogen metabolism in the body. While generally well-tolerated, individuals using hormonal contraceptives or with hormone-sensitive conditions should consult their healthcare provider. This ensures there are no potential interactions or unintended effects on their specific medical regimen.

Question 23

Is it safe to use supplements with these ingredients during pregnancy or while breastfeeding?

Accepted Answer

The safety of this specific combination of ingredients during pregnancy or breastfeeding has not been definitively established. For this reason, it is generally recommended that pregnant or breastfeeding individuals consult their healthcare professional. Medical advice is crucial before taking any new supplement.

Question 24

Can ingredients such as turmeric, DIM, or green tea extract cause gastrointestinal upset?

Accepted Answer

Some individuals may experience mild gastrointestinal discomfort, such as nausea, heartburn, or indigestion. This is particularly true when taking supplements containing turmeric, DIM, or green tea extract on an empty stomach. Taking the supplement with food can often help minimize these effects.

Question 25

Are there any known allergen concerns related to ingredients like milk thistle or broccoli sprout powder?

Accepted Answer

Individuals with known allergies to plants in the Asteraceae family, such as ragweed, marigolds, or daisies, may be sensitive to milk thistle. Similarly, those with a known allergy to broccoli or other cruciferous vegetables should be aware of sulforaphane from broccoli sprout powder. Always check for known sensitivities before use.

Question 26

Do any of the ingredients in this supplement interact with thyroid medications?

Accepted Answer

Certain compounds found in cruciferous vegetables, like those providing sulforaphane and I3C, may influence thyroid function, though typically at very high doses. While significant interaction with thyroid medications is not commonly reported at typical supplement levels, individuals on thyroid medication should consult their doctor. This is important to ensure no adverse effects.

Question 27

What are the long-term safety considerations for taking a combination of these ingredients?

Accepted Answer

Many of the individual ingredients, such as milk thistle and turmeric, have a history of safe use in various health traditions. However, specific long-term studies on this precise combination of ingredients are limited. It is prudent to periodically review any long-term supplement use with a healthcare professional.

Question 28

Are there liver safety concerns associated with green tea extract in supplements?

Accepted Answer

Rare cases of liver enzyme elevation have been reported with very high doses of green tea extract, particularly when taken on an empty stomach. This product uses a decaffeinated green tea extract with polyphenols. Adhering to recommended serving sizes and taking with food can help mitigate potential risks, but individuals with liver conditions should consult a doctor.

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Ingredient	Amount per serving
Calcium-D-Glucarate	150 mg
Indole-3-Carbinol	150 mg
Sunphenon decaffeinated Green Tea extract	100 mg
Turmeric extract	50 mg
Milk Thistle extract	50 mg
Di-Indolylmethane	50 mg
Rosemary extract	25 mg
Lycopene	5 mg
Sulforaphane	200 mcg

EstroSense
Natural Factors WS WomenSense

EstroSense

Score 85.0

Analysis

Effectiveness for goals

Dosage, timing & forms

Safety & interactions

Ingredients

Categories

Goals

Recommended Alternatives

Triple Action Cruciferous Vegetable Extract

Silymarin Complex

Green Tea

Triple Action Cruciferous Vegetable Extract

Silymarin Complex

Super Antioxidants

EGCg Green Tea Extract 400 mg

Double Strength Silymarin 300 mg

Lycopene 25 mg

Triple Action Cruciferous Vegetable Extract

Silymarin Complex

Green Tea

Triple Action Cruciferous Vegetable Extract

Silymarin Complex

Super Antioxidants

EstroSenseNatural Factors WS WomenSense

EstroSense

leaderboard Score 85.0

insightsAnalysiswarningMedical Disclaimer

boltEffectiveness for goals

scheduleDosage, timing & forms

health_and_safetySafety & interactions

Ingredients

Categories

Goals

Recommended Alternatives

Triple Action Cruciferous Vegetable Extract

Silymarin Complex

Green Tea

Triple Action Cruciferous Vegetable Extract

Silymarin Complex

Super Antioxidants

EGCg Green Tea Extract 400 mg

Double Strength Silymarin 300 mg

Lycopene 25 mg

Triple Action Cruciferous Vegetable Extract

Silymarin Complex

Green Tea

Triple Action Cruciferous Vegetable Extract

Silymarin Complex

Super Antioxidants

EstroSense
Natural Factors WS WomenSense

Score 85.0

Analysis

Effectiveness for goals

Dosage, timing & forms

Safety & interactions