Mega-One
Source Naturals
Mega-One
4.7
★ ★ ★ ★ ★
(612 ratings)
Vitamin B6 85 mg
Manganese 6 mg
Molybdenum 100 mcg
Thiamin 85 mg
Vitamin B5 85 mg
Rutin 21 mg
PABA 85 mg
Score 68.0
A high-potency B-complex and Vitamin C rich multivitamin, offering good energy and immune support, but significantly lacking in essential minerals like Calcium, Magnesium, and sufficient Vitamin D, and uses some non-optimal vitamin forms.
Quantity: 60 Tablet(s)Servings size: 1 Tablet(s) (60 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
Cognitive Support
leaderboard Score 68.0
A high-potency B-complex and Vitamin C rich multivitamin, offering good energy and immune support, but significantly lacking in essential minerals like Calcium, Magnesium, and sufficient Vitamin D, and uses some non-optimal vitamin forms.
insights Analysis
Source Naturals Mega-One is marketed as a comprehensive daily supplement targeting a vast array of health goals from general wellness to specific areas like cognitive function, immunity, and anti-aging. It stands out with its very high concentrations of B vitamins (Thiamine, Riboflavin, Niacinamide, B6, Pantothenic Acid) and Vitamin C, which are beneficial for energy metabolism and antioxidant protection. The formula also includes a good selection of trace minerals such as Zinc, Selenium, Chromium, and Molybdenum, many in chelated forms for better absorption, along with unique additions like Inositol, PABA, Choline, and Bioflavonoids that support various bodily functions including nerve health and capillary integrity. However, its mineral profile is noticeably weak in crucial areas like Calcium (80mg total) and Magnesium (40mg total), making it inadequate for primary bone health or comprehensive mineral repletion according to nutritionists. The Vitamin D3 content at 400 IU is also significantly below current public health recommendations for most adults. Furthermore, the use of Folic Acid instead of active methylfolate, and Cyanocobalamin for Vitamin B12 instead of methylcobalamin, means it doesn't offer the most bioavailable forms of these key B vitamins, which can be a concern for individuals with genetic variations affecting nutrient metabolism. Online reviews often praise its energy-boosting effects, likely due to the high B-vitamin complex, but some users may find the large tablet size inconvenient.
- Provides a very comprehensive range of B vitamins at high potencies, beneficial for energy production and nervous system health.
- Contains a robust dose of Vitamin C and Zinc, offering strong support for immune function.
- Includes beneficial adjunctive nutrients such as Choline, Inositol, PABA, and a Bioflavonoid Complex for broad health benefits.
- Utilizes some chelated mineral forms (e.g., Manganese Ascorbate, Zinc Ascorbate, Molybdenum Amino Acid Chelate) for potentially better absorption.
- Reasonable price per serving makes it an accessible option for a multivitamin.
- Offers extremely low levels of Calcium and Magnesium, falling far short of daily requirements and undermining its effectiveness for bone and overall mineral balance.
- Contains only 400 IU of Vitamin D3, which is considerably below the 1000-5000 IU or more often recommended by health professionals for optimal levels.
- Uses synthetic forms of Folate (Folic Acid) and Vitamin B12 (Cyanocobalamin), which may not be optimally utilized by all individuals, particularly those with MTHFR gene variations.
- The very high dose of Vitamin A (12,000 IU) could potentially be excessive or lead to accumulation over time, especially if other dietary sources of Vitamin A are high.
- The high quantity of Pyridoxine Hydrochloride (Vitamin B6) at 85mg daily, while generally safe, might cause neuropathy in very sensitive individuals with long-term use, though this is rare at this dose.
- Individuals prone to B6-induced neuropathy should monitor intake due to the high Pyridoxine Hydrochloride content and consider alternative forms if issues arise.
- Pregnant individuals should consult a healthcare professional regarding Vitamin A dosage, as 12000 IU can be high if combined with other dietary sources or supplements.
- Individuals with hemochromatosis or who are iron-sensitive should avoid this product due to the iron content unless advised by a doctor, as excessive iron can be harmful.
$13.59($0.22 per serving)
 iHerb | $ 13.59 | |
 Pure Formulas | $ 15.75 |
bolt Effectiveness for goals
B vitamins, including Thiamine, Riboflavin, Niacinamide, B6, Folate, B12, Biotin, and Pantothenic Acid, play crucial roles in cellular metabolism. They help convert food into energy, support nerve function, and maintain healthy skin, hair, and eyes. This combination supports various metabolic processes throughout the body.
Vitamins A, C, and E are known for their antioxidant properties. They work together to help protect cells from oxidative stress and free radical damage. Vitamin C also supports collagen formation and immune function, while Vitamin A is important for vision and immune health, and Vitamin E supports cell membrane integrity.
Zinc, copper, and selenium are essential trace minerals that often interact in the body. While they each have distinct roles in immune function and antioxidant defense, their absorption can sometimes be competitive. Supplements often balance these to ensure adequate intake of each without significantly hindering the others.
Different forms of calcium and magnesium, such as calcium citrate, calcium ascorbate, magnesium oxide, and magnesium citrate, can offer varied absorption profiles. Calcium supports bone health and nerve function, while magnesium is involved in over 300 enzymatic reactions, including muscle and nerve function. Using multiple forms aims to enhance bioavailability and address diverse physiological needs.
Choline is essential for cell membrane structure, neurotransmitter synthesis, and fat metabolism. Inositol is involved in cell signaling and nerve transmission. Para-Aminobenzoic Acid (PABA) is sometimes included for its reported effects on skin, hair, and certain metabolic pathways, though its essentiality in human nutrition is still debated.
schedule Dosage, timing & forms
Generally, it is recommended to take multivitamin and mineral supplements with a meal. This can help enhance the absorption of fat-soluble vitamins and may reduce the potential for stomach upset. Taking it consistently at the same time each day can also help establish a routine.
Calcium can sometimes interfere with the absorption of non-heme iron. While many broad-spectrum supplements combine them, individuals with specific iron needs might consider separating their intake by a few hours. Pairing iron with Vitamin C can help enhance its absorption.
Certain ingredients, such as Vitamin K, Iron, and Calcium, have the potential to interact with some medications, including blood thinners, certain antibiotics, and thyroid hormones. It is always advisable to consult a healthcare professional before starting any new supplement, especially if you are taking prescription medications. They can provide personalized advice regarding potential interactions.
There is no strict rule for taking a multivitamin and mineral supplement in the morning versus the evening. The most important factor is consistency, so choose a time that fits best into your daily routine. Taking it with your largest meal of the day is often recommended to optimize nutrient absorption.
Combining different forms of a nutrient, like Calcium Citrate and Calcium Ascorbate, can offer varied absorption profiles and provide additional benefits. Calcium Citrate is often well-absorbed, while Calcium Ascorbate provides both calcium and Vitamin C. This approach can also enhance overall nutrient availability.
health_and_safety Safety & interactions
This supplement contains Vitamin E, which at high doses may have mild anticoagulant effects. Individuals taking blood-thinning medications should consult their healthcare provider before use to assess potential interactions. Iron and some other minerals can also interact with certain medications.
This supplement contains iodine, which is essential for thyroid function but can interact with certain thyroid medications or affect individuals with pre-existing thyroid conditions. It's advisable to discuss this with a healthcare professional before use. Iron can also impact the absorption of thyroid hormones.
Iron can interfere with the absorption of certain antibiotics, like tetracyclines and quinolones, and thyroid hormones. It may also compete with calcium for absorption if taken simultaneously in large amounts. Separate doses by a few hours if recommended by a healthcare provider.
Some individuals may experience stomach upset, nausea, or constipation, especially due to iron or high doses of Vitamin C. Taking the supplement with food can often help reduce these gastrointestinal effects. If symptoms persist, consult a healthcare provider.
This supplement contains 11 mg of iron. Individuals with iron overload conditions such as hemochromatosis should avoid iron supplementation unless specifically advised by their doctor. Unnecessary iron intake can exacerbate these conditions.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Total Carbohydrates | 1 Gram(s) |
Vitamin A | 12000 IU |
Vitamin C | 250 mg |
Vitamin D3 | 400 IU |
Vitamin E | 100 IU |
Thiamine | 85 mg |
Riboflavin | 85 mg |
Niacinamide | 85 mg |
Vitamin B6 | 85 mg |
Folate | 420 mcg |
Vitamin B12 | 85 mcg |
Biotin | 85 mcg |
Pantothenic Acid | 85 mg |
Calcium | 40 mg |
Iron | 11 mg |
Iodine | 150 mcg |
Magnesium | 20 mg |
Zinc | 15 mg |
Selenium | 50 mcg |
Copper | 1 mg |
Manganese | 6 mg |
Chromium | 100 mcg |
Molybdenum | 100 mcg |
Potassium | 10 mg |
Choline Bitartrate | 85 mg |
Para-Aminobenzoic Acid | 85 mg |
Inositol | 85 mg |
Bioflavonoid Complex | 25 mg |
Rutin | 21 mg |
Hesperidin | 5 mg |
Boron | 1 mg |
Categories
Thiamin 90.0
Providing 85mg of Thiamine (Vitamin B1) is a very high dose, far exceeding the daily recommended allowance. This can be beneficial for energy production, nervous system support, and addressing potential deficiencies, particularly for those with high metabolic demands or absorption issues. This high potency is a strength for B1 status and widely recognized for its role in energy.
Riboflavin 90.0
At 85mg, the Riboflavin (Vitamin B2) content is exceptionally high, significantly surpassing daily needs. This potency strongly supports cellular energy production, antioxidant defense, and healthy vision. This elevated dose ensures comprehensive coverage for B2-dependent metabolic pathways, and is a key factor in energy-related user reviews.
Vitamin B5 90.0
With 85mg of Pantothenic Acid (Vitamin B5), this product delivers a very high dose that is highly beneficial for energy metabolism, adrenal gland function, and stress response. This strong concentration ensures excellent support for these physiological processes, often a reason for positive user feedback regarding energy.
Goals
Metabolism Boost 80.0
Mega-One excels in providing high doses of almost all B vitamins (Thiamine, Riboflavin, Niacinamide, Pantothenic Acid, B6, B12, Biotin, Folate), which are fundamental coenzymes for energy production and macronutrient metabolism. The inclusion of Chromium and Iodine further supports metabolic functions. This comprehensive B-vitamin profile makes it highly effective for boosting overall metabolic efficiency.
Energy 80.0
Mega-One is particularly strong for energy support due to its very high concentrations of B vitamins, which are crucial for cellular energy production. These vitamins help the body efficiently convert carbohydrates, fats, and proteins into usable energy, often leading to noticeable improvements in energy levels reported in online reviews. The inclusion of iron also helps prevent iron-deficiency related fatigue.
Productivity Boost 80.0
By providing a comprehensive and high-potency array of B vitamins and essential minerals, this product significantly supports energy metabolism and cellular function, which are foundational for sustained productivity. The energy-boosting effects derived from efficient nutrient conversion contribute to improved stamina and mental alertness, indirectly enhancing overall productivity throughout the day, a common theme in user reviews.
Recommended Alternatives
85 Value 
Alive! Men's Ultra Potency Complete Multivitamin
Nature's Way
4.7
★★★★★
(35418 ratings)
This men's multivitamin offers a powerful blend of high-potency vitamins and minerals, along with targeted blends for male health, at a price per serving comparable to or slightly lower than Mega-One. Its superior ingredient forms and comprehensive support make it an excellent value for a high-quality multi.
75 Value 
Formula V VM-75
Solgar
4.7
★★★★★
(5458 ratings)
Solgar's VM-75 is a well-established multivitamin that provides a strong 'B-complex' profile and good levels of other essential vitamins and minerals. It offers a noticeable upgrade in quality and potency compared to Mega-One at a similar or slightly lower price per serving, representing solid value for general nutritional support.
70 Value 
Super Multi Iron Free
Natural Factors
4.7
★★★★★
(1054 ratings)
This iron-free multivitamin offers a balanced spectrum of vitamins and minerals, including some beneficial forms, at a lower price per serving than Mega-One. It is a good choice for individuals who do not require supplemental iron but still seek a comprehensive daily multi with improved ingredient quality for the cost.
90 Performance 
Two-Per-Day Capsules
Life Extension
4.7
★★★★★
(85932 ratings)
Life Extension's Two-Per-Day is consistently rated highly by nutritionists for its superior formulation, incorporating highly bioavailable and active forms of vitamins (e.g., L-5-Methyltetrahydrofolate, Methylcobalamin, Pyridoxal 5'-Phosphate) and chelated minerals. It provides comprehensive antioxidant and cellular support, significantly surpassing Mega-One in quality and efficacy.
92 Performance 
Source of Life Gold Tablets
Natures Plus
4.7
★★★★★
(1852 ratings)
This product sets a high standard for whole-food based multivitamins, delivering an extensive blend of organic nutrients, enzymes, and probiotics. Its commitment to bioavailable forms and synergistic ingredients offers a very high level of comprehensive nutritional support, making it a top-tier choice for those prioritizing ingredient quality.
95 Performance 
Advanced Nutrients
Thorne
4.6
★★★★★
(851 ratings)
Thorne is renowned for its exceptionally high-quality, hypoallergenic formulations that utilize highly bioavailable forms of nutrients, including activated B vitamins and chelated minerals. This product offers a meticulously balanced and potent blend of essential vitamins, minerals, and phytonutrients, designed for optimal absorption and comprehensive health support, making it a superior choice recommended by many practitioners.
65 Budget 
Daily Vits
NOW
4.7
★★★★★
(7216 ratings)
This NOW product offers a comprehensive range of daily vitamins and minerals at a significantly lower cost per serving compared to Mega-One. It provides solid foundational support for general health and well-being, making it a very economical choice.
72 Budget 
One Daily Superfood Multi-Vitamin no Iron
Paradise Earth's Blend
4.7
★★★★★
(5870 ratings)
This multivitamin provides good value by including a broad range of vitamins, minerals, and superfood blends at a lower price per serving than Mega-One. Its use of more bioavailable forms like methylcobalamin for B12 and L-Methylfolate for Folate makes it a superior option for nutrient absorption and overall effectiveness compared to many budget multis.
80 Budget 
Alive! Once Daily Women's Ultra Potency
Nature's Way
4.7
★★★★★
(61246 ratings)
This women's-specific multivitamin offers a higher potency and more diverse array of ingredients, including various beneficial blends, at a comparable or slightly lower price per serving. Its comprehensive nutrient profile and inclusion of whole-food concentrates make it a robust choice for overall health support.
85 Value
Alive! Men's Ultra Potency Complete Multivitamin
Nature's Way
4.7
★★★★★
(35418 ratings)
This men's multivitamin offers a powerful blend of high-potency vitamins and minerals, along with targeted blends for male health, at a price per serving comparable to or slightly lower than Mega-One. Its superior ingredient forms and comprehensive support make it an excellent value for a high-quality multi.
75 Value
Formula V VM-75
Solgar
4.7
★★★★★
(5458 ratings)
Solgar's VM-75 is a well-established multivitamin that provides a strong 'B-complex' profile and good levels of other essential vitamins and minerals. It offers a noticeable upgrade in quality and potency compared to Mega-One at a similar or slightly lower price per serving, representing solid value for general nutritional support.
70 Value
Super Multi Iron Free
Natural Factors
4.7
★★★★★
(1054 ratings)
This iron-free multivitamin offers a balanced spectrum of vitamins and minerals, including some beneficial forms, at a lower price per serving than Mega-One. It is a good choice for individuals who do not require supplemental iron but still seek a comprehensive daily multi with improved ingredient quality for the cost.
90 Performance
Two-Per-Day Capsules
Life Extension
4.7
★★★★★
(85932 ratings)
Life Extension's Two-Per-Day is consistently rated highly by nutritionists for its superior formulation, incorporating highly bioavailable and active forms of vitamins (e.g., L-5-Methyltetrahydrofolate, Methylcobalamin, Pyridoxal 5'-Phosphate) and chelated minerals. It provides comprehensive antioxidant and cellular support, significantly surpassing Mega-One in quality and efficacy.
92 Performance
Source of Life Gold Tablets
Natures Plus
4.7
★★★★★
(1852 ratings)
This product sets a high standard for whole-food based multivitamins, delivering an extensive blend of organic nutrients, enzymes, and probiotics. Its commitment to bioavailable forms and synergistic ingredients offers a very high level of comprehensive nutritional support, making it a top-tier choice for those prioritizing ingredient quality.
95 Performance
Advanced Nutrients
Thorne
4.6
★★★★★
(851 ratings)
Thorne is renowned for its exceptionally high-quality, hypoallergenic formulations that utilize highly bioavailable forms of nutrients, including activated B vitamins and chelated minerals. This product offers a meticulously balanced and potent blend of essential vitamins, minerals, and phytonutrients, designed for optimal absorption and comprehensive health support, making it a superior choice recommended by many practitioners.