Product Image

SharpMind Stress

Solaray
4.7
★ ★ ★ ★ ★
(80 ratings)
Theanine 200 mg
Ashwagandha 120 mg
GABA 100 mg
Shiitake Mushroom 100 mg
Product Image
Score73
A well-dosed calm-focus formula built around L-theanine and branded ashwagandha, with GABA adding modest relaxation support. It is better for stress-related distraction than immediate energy, alertness, or targeted memory support.
How scoring works
Quantity:30 VegCap(s) • (30 servings)
Goals:
Stress Relief
Brain Health
Cognitive Support
Mood Support
Productivity Boost
Sleep Support
Mental Focus

Score 73

A well-dosed calm-focus formula built around L-theanine and branded ashwagandha, with GABA adding modest relaxation support. It is better for stress-related distraction than immediate energy, alertness, or targeted memory support.
How scoring works
$26.39($0.87 per serving)
Walmart
$ 26.39
iHerb
$ 26.39
Pure Formulas
$ 26.39
Vitacost
$ 26.39
Report prices

Analysis

L-theanine at 200 mg and Shoden ashwagandha form the clearest part of the formula. They provide a well-aligned base for calm focus, stress resilience, and mood support without relying on a stimulant.

GABA adds another relaxation pathway, although its 100 mg amount and standard form make it a secondary contributor. Shiitake grown on oat has little clear relevance to the stated stress and cognitive goals at the listed amount.

The blend fits people whose focus or sleep is disrupted by tension more than those seeking immediate alertness or memory support. The Shoden entries appear to repeat leaf, root, and withanolide descriptors for the same branded amount, while the supplied record does not show non-active ingredients.

Who is it for
  • Adults whose focus drops when stress or tension rises
  • People seeking non-stimulant calm-focus support
  • People who want one daily capsule for stress resilience
Best for
  • Stress relief and calm focus
  • Mood support linked to daily tension
  • Relaxation when a busy mind interferes with sleep

Pros

  • Provides 200 mg of L-theanine
  • Uses branded Shoden ashwagandha at a practical amount
  • Combines complementary calm-focus and relaxation pathways

Cons

  • GABA is modestly dosed and lacks a premium source marker
  • Shiitake grown on oat adds little direct value for the main goals
  • No direct support for alertness, brain energy, or circadian timing

Warnings

  • The combined calming ingredients may reduce alertness in sensitive users, so first use is better when driving or demanding work is not required.
  • Review the formula before combining it with sedatives or several other calming supplements because GABA, L-theanine, and ashwagandha may add to relaxation.
  • The supplied record omits non-active ingredients and identifies shiitake grown on oat, which matters for users screening excipients or avoiding oat-derived material.

Nutrient quality

83 Highest impact

Branded ashwagandha and a well-aligned theanine amount provide strong support for stress-related calm and focus. Modest GABA and a small shiitake amount add less certain value.

.

Ingredient transparency

77 High impact

Each listed active has a specific amount and no proprietary blend hides the formula. Repeated Shoden descriptors, missing intake directions, and absent non-active ingredients reduce complete clarity.

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Customer satisfaction

62 Moderate impact

The aggregate rating is favorable, but the review count is limited. No review comments are supplied, so tolerance, drowsiness, and purpose alignment cannot be assessed directly.

.

Value for money

65 High impact

Meaningful theanine and branded ashwagandha provide fair value for a focused stress formula. Premium serving cost and a low-value shiitake addition limit category competitiveness.

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Report analysis

Goals

Stress Relief
Stress Relief
Impact
Highest effect
A+ Goal FitA+ Strength of SupportA CoverageA Formula Quality
Ashwagandha · 120 mgGABA · 100 mgTheanine · 200 mg

Branded Shoden ashwagandha and a well-aligned theanine amount directly support HPA-axis regulation and calm focus. GABA adds a secondary inhibitory pathway without stimulants.

The branded adaptogen and clearly listed amounts provide strong dose confidence. Shiitake is the only notable addition that does not materially strengthen stress relief.

Study evidence
Ashwagandha Supportive 47 studies
GABA Supportive 6 studies
Theanine Supportive 16 studies
Brain Health
Brain Health
Impact
Highest effect
A- Goal FitA- Strength of SupportB CoverageA- Formula Quality
Ashwagandha · 120 mg

Branded Shoden ashwagandha and theanine target stress-related cognitive fatigue and calm focus. GABA adds relaxation, while shiitake contributes little direct cognitive evidence.

Theanine reaches a useful amount and Shoden sits at the lower end of its typical range. Clear amounts and a clinically studied extract support a coherent mental-resilience formula.

Study evidence
Ashwagandha Supportive 12 studies
Theanine Supportive 17 studies
Cognitive Support
Cognitive Support
Impact
Highest effect
A- Goal FitA- Strength of SupportB+ CoverageB+ Formula Quality
Ashwagandha · 120 mgTheanine · 200 mg

Branded ashwagandha and a well-aligned amount of L-theanine form a strong calm-focus and stress-resilience combination. Both ingredients have relevant human evidence, with the most direct benefit expected when stress interferes with attention.

Shoden and L-theanine are clearly disclosed at practical amounts, while the GABA and shiitake additions are less persuasive. The formula is coherent and focused, though it emphasizes stress-related cognition rather than memory or cerebral circulation.

Study evidence
Ashwagandha Supportive 17 studies
Theanine Supportive 25 studies
Mood Support
Mood Support
Impact
Highest effect
A- Goal FitA- Strength of SupportB CoverageB+ Formula Quality
Ashwagandha · 120 mg

Shoden ashwagandha and 200 mg of L-theanine provide direct support for stress resilience and calm focus. Both are supplied at clinically plausible amounts, while oral GABA adds less certain central effects.

The formula covers stress adaptation and acute relaxation with a compact ingredient list. Shiitake contributes little to the selected goal but does not overwhelm an otherwise coherent combination.

Study evidence
Ashwagandha Supportive 29 studies
GABA Supportive 12 studies
Theanine Supportive 12 studies
Productivity Boost
Productivity Boost
Impact
Highest effect
B Goal FitA- Strength of SupportB- CoverageB+ Formula Quality
Theanine · 200 mg

Standardized ashwagandha and L-theanine provide a clear non-stimulant approach to stress-related distraction and mental calm. Both main actives have credible human evidence for stress or attention, though direct output and performance effects vary.

The formula covers stress modulation and calm focus but not acute alertness or strong neurotransmitter precursor support. Ashwagandha and theanine pair coherently for calm focus without stimulant tension.

Study evidence
Ashwagandha Supportive 6 studies
Theanine Supportive 5 studies
Sleep Support
Sleep Support
Impact
High effect
B- Goal FitA- Strength of SupportB CoverageB Formula Quality
Theanine · 200 mg

The formula provides a well-dosed amount of L-theanine with branded Shoden ashwagandha and a modest GABA dose for stress-related relaxation. It may suit a busy mind at night, but it does not directly support circadian timing.

Active amounts are disclosed, and the branded ashwagandha source adds useful quality detail. Shiitake has little clear sleep relevance, while the concentrated group of main actives otherwise keeps the design reasonably focused.

Study evidence
Ashwagandha Supportive 18 studies
GABA Supportive 4 studies
Theanine Supportive 8 studies
Mental Focus
Mental Focus
Impact
High effect
B- Goal FitB+ Strength of SupportC+ CoverageB+ Formula Quality
Theanine · 200 mg

A full L-theanine amount and branded Shoden ashwagandha provide a strong calm-focus base for stress-related distraction. GABA reinforces relaxation, while the mushroom addition has limited direct relevance at the listed amount.

The blend is concise and transparently dosed, with a standardized ashwagandha form that supports dose confidence. Its narrow calming profile lacks alertness, brain-energy, and neurotransmitter-precursor pathways, so it is better for tension than demanding acute performance.

Study evidence
Ashwagandha Supportive 12 studies
Theanine Supportive 19 studies

Ingredients

IngredientAmount per serving
Shoden (Ashwagandha Leaf Extract, Ashwagandha root extract, Withanolides)
 120 mg
L-Theanine
200 mg
Shiitake Mushroom (Oat)
 100 mg
Gamma Amino Butyric Acid
100 mg
Gluten Free Adults 18–50 Vegan Dairy Free Women Vegetarian
Report overview
Theanine · 200 mg OverallScore88
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The explicitly named L-theanine is fully disclosed at a well-aligned amount. Its generic source does not add branded purity assurance. Theanine pricing is premium, while the meaningful dose of branded Shoden ashwagandha improves the value by one tier.

View ingredientView products
Ashwagandha (Ashwagandha Leaf Extract, Ashwagandha root extract, Withanolides) · 120 mg OverallScore84
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

Shoden is a clinically studied extract supplied at the lower end of its usual daily range. The branded amount is clearly represented despite repeated descriptors, although no absorption enhancer is included. A serving cost above the midpoint is partly justified by the supporting theanine and stress-focused ingredients.

View ingredientView products
GABA · 100 mg OverallScore73
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD- Value
The formula discloses a modest amount of standard GABA that fits a multi-ingredient stress product but lacks a premium source marker. A vegetable capsule offers practical delivery, while L-theanine and ashwagandha make GABA only one part of the formula. The cost per serving is high relative to the amount and type of GABA supplied.
View ingredientView products
Loading alternative details
78 Performance

Serenelle

Quality Of Life
<p>Sensoril ashwagandha, theanine, PharmaGABA, and lemon balm are supplied at meaningful amounts in a focused calming formula. Clear active amounts or branded adaptogen forms improve assessability over the original’s incomplete directions and excipient details. Combined calming ingredients can still impair alertness.</p>
75 Performance

Ultra Strength Goodbye Stress

OLLY
<p>Ashwagandha, GABA, theanine, and lemon balm create a coherent calming blend, but all four doses are modest. Clear active amounts or branded adaptogen forms improve assessability over the original’s incomplete directions and excipient details. Combined calming ingredients can still impair alertness.</p>
76 Performance

200 mg of Zen

Allergy Research Group
<p>L-theanine and a substantial GABA amount form a focused relaxation stack with fully disclosed doses. Clear active amounts or branded adaptogen forms improve assessability over the original’s incomplete directions and excipient details. Combined calming ingredients can still impair alertness.</p>
86 Budget

Anxiety & Stress Relief

Nature's Bounty
<p>Ashwagandha and theanine provide a focused, meaningfully dosed stress-support pair without unrelated actives. The lower serving cost improves economy while retaining ashwagandha, GABA, or theanine support. The blend may lean more toward relaxation than daytime focus.</p>
83 Budget

GABA Soothe

Jarrow Formulas
<p>Sensoril ashwagandha, theanine, and GABA create a concise calming formula at useful amounts. The lower serving cost improves economy while retaining ashwagandha, GABA, or theanine support. The blend may lean more toward relaxation than daytime focus.</p>
83 Budget

ZenMind

NutriCology
<p>Branded L-theanine and a substantial GABA amount form a focused relaxation stack with fully disclosed doses. The lower serving cost improves economy while retaining ashwagandha, GABA, or theanine support. The blend may lean more toward relaxation than daytime focus.</p>
74 Value

Chewable GABA

NOW
<p>A substantial GABA amount anchors the calming chewable, while taurine, inositol, and L-theanine provide only modest support. A favorable serving cost and clearer calming actives improve value over the original while preserving stress support. Some options are narrower and may be better suited to evening use.</p>
69 Value

Goodbye Stress Berry Verbena

OLLY
<p>GABA, L-theanine, and lemon balm create a coherent gummy for gentle stress support, but all three amounts are modest. A favorable serving cost and clearer calming actives improve value over the original while preserving stress support. Some options are narrower and may be better suited to evening use.</p>
74 Value

Ashwagandha+ Relax

Himalaya
<p>Ashwagandha anchors a coherent calming blend with GABA and supporting herbs. A favorable serving cost and clearer calming actives improve value over the original while preserving stress support. Some options are narrower and may be better suited to evening use.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
    Fatima K; Malik J; Muskan F; Raza G; Waseem A; Shahid H; Jaffery SF; Khan U; Zaheer MK; Shaikh Y; Rashid AM · Human psychopharmacology · 2024
    Meta-analysis254 participants5 studies pooledStress Relief Mood Support forAshwagandha
  2. The Impact of Ashwagandha on Stress, Sleep Quality, and Food Cravings in College Students: Quantitative Analysis of a Double-Blind Randomized Control Trial.
    O'Connor J; Lindsay K; Baker C; Kirby J; Hutchins A; Harris M · Journal of medicinal food · 2022
    Randomized trial60 participantsStress Relief forAshwagandha
  3. Dual impact of Ashwagandha: Significant cortisol reduction but no effects on perceived stress - A systematic review and meta-analysis.
    Albalawi AA · Nutrition and health · 2025
    Meta-analysis488 participants13 studies pooledStress Relief forAshwagandha
  4. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
    Ritsner MS; Miodownik C; Ratner Y; Shleifer T; Mar M; Pintov L; Lerner V · The Journal of clinical psychiatry · 2011
    Randomized trial60 participantsStress Relief Mood Support forTheanine
  5. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
    Sarris J; Byrne GJ; Cribb L; Oliver G; Murphy J; Macdonald P; Nazareth S; Karamacoska D; Galea S; Short A; Ee C; Birling Y; Menon R; Ng CH · Journal of psychiatric research · 2020
    Randomized trial46 participantsStress Relief Sleep Support forTheanine
  6. Effect of Combined Ingestion of L-Theanine and L-Arginine for Short-Term Psychological Stress in Young Adults: A Randomized Placebo-Controlled Study.
    Furushima D; Sugiyama I; Nomura Y; Unno K; Yamada H · Journal of nutritional science and vitaminology · 2023
    Randomized trial120 participantsStress Relief forTheanine
  7. Effects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
    Zhu X; Zeng Q; Lei Y; Xu D · Frontiers in pharmacology · 2026
    Meta-analysis1,249 participants20 studies pooledMental Focus forAshwagandha
  8. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsMental Focus Mood Support Brain Health Cognitive Support Productivity Boost forAshwagandha
  9. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B · Nutrition reviews · 2025
    Meta-analysis50 studies pooledMental Focus Brain Health Cognitive Support forTheanine
  10. A double-blind, placebo-controlled study evaluating the effects of caffeine and L-theanine both alone and in combination on cerebral blood flow, cognition and mood.
    Dodd FL; Kennedy DO; Riby LM; Haskell-Ramsay CF · Psychopharmacology · 2016
    Randomized trial24 participantsMental Focus forTheanine
  11. Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.
    Rogers PJ; Smith JE; Heatherley SV; Pleydell-Pearce CW · Psychopharmacology · 2008
    Randomized trial48 participantsMental Focus Productivity Boost forTheanine
  12. Promising, but Not Completely Conclusive-The Effect of l-Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials.
    Mátyus RO; Szikora Z; Bodó D; Vargáné Szabó B; Csupor É; Csupor D; Tóth B · Journal of clinical medicine · 2025
    Meta-analysis148 participants5 studies pooledMental Focus forTheanine
  13. Does Ashwagandha supplementation have a beneficial effect on the management of anxiety and stress? A systematic review and meta-analysis of randomized controlled trials.
    Akhgarjand C; Asoudeh F; Bagheri A; Kalantar Z; Vahabi Z; Shab-Bidar S; Rezvani H; Djafarian K · Phytotherapy research : PTR · 2022
    Meta-analysis1,002 participants12 studies pooledMood Support forAshwagandha
  14. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.
    Williams JL; Everett JM; D'Cunha NM; Sergi D; Georgousopoulou EN; Keegan RJ; McKune AJ; Mellor DD; Anstice N; Naumovski N · Plant foods for human nutrition (Dordrecht, Netherlands) · 2020
    Systematic review9 studies pooledMood Support forTheanine
  15. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
    Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
    Meta-analysis29 participants29 studies pooledMood Support forTheanine Mood Support forAshwagandha
  16. Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials.
    Gerolymos C; Saddier E; Boyer L; Fond G · Molecular psychiatry · 2026
    Meta-analysis1,168 participants31 studies pooledMood Support Productivity Boost forTheanine
  17. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsBrain Health Cognitive Support forAshwagandha
  18. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsBrain Health Cognitive Support Mental Focus forAshwagandha
  19. A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
    Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
    Randomized trial85 participantsBrain Health Mental Focus forAshwagandha
  20. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
    Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
    Randomized trial130 participantsBrain Health Sleep Support Stress Relief forAshwagandha
  21. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsBrain Health Cognitive Support Sleep Support forTheanine
  22. A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
    Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
    Randomized trialBrain Health Stress Relief forTheanine
  23. Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
    Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP · Neuropharmacology · 2012
    Randomized trial27 participantsBrain Health Cognitive Support forTheanine
  24. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
    Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T · Journal of medicinal food · 2021
    Randomized trialBrain Health Mental Focus Productivity Boost forTheanine
  25. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
    Randomized trial54 participantsCognitive Support Mental Focus forAshwagandha
  26. Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
    Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
    Randomized trial58 participantsCognitive Support Mental Focus forAshwagandha
  27. Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study.
    Dassanayake TL; Wijesundara D; Kahathuduwa CN; Weerasinghe VS · Nutritional neuroscience · 2023
    Randomized trial32 participantsCognitive Support forTheanine
  28. Acute effects of theanine, caffeine and theanine-caffeine combination on attention.
    Kahathuduwa CN; Dassanayake TL; Amarakoon AMT; Weerasinghe VS · Nutritional neuroscience · 2018
    Clinical trial20 participantsCognitive Support Mental Focus forTheanine
  29. Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.
    Choudhary D; Bhattacharyya S; Bose S · Journal of dietary supplements · 2018
    Randomized trial50 participantsMental Focus forAshwagandha
  30. Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED · Neurology and therapy · 2024
    Randomized trial30 participantsMental Focus Productivity Boost Stress Relief forTheanine
  31. Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study.
    Karunaratne UW; Dassanayake TL · Nutritional neuroscience · 2025
    Randomized trial24 participantsMental Focus forTheanine
  32. A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.
    West RE; Biswas A; Rao R; Tayade H; Ademola J · Journal of medicine and life · 2026
    Randomized trial141 participantsMood Support forAshwagandha
  33. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
    Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
    Randomized trial64 participantsMood Support Stress Relief forAshwagandha
  34. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
    McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
    Randomized trial186 participantsMood Support forAshwagandha
  35. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
    Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
    Randomized trial63 participantsMood Support Stress Relief forGABA
  36. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
    Deligiannidis KM; Kroll-Desrosiers AR; Mo S; Nguyen HP; Svenson A; Jaitly N; Hall JE; Barton BA; Rothschild AJ; Shaffer SA · Psychoneuroendocrinology · 2017
    Cohort study56 participantsMood Support forGABA
  37. The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
    Wang J; Liu G; Xu K; Ai K; Huang W; Zhang J · Human brain mapping · 2023
    Case-control study69 participantsMood Support forGABA
  38. Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis.
    Truong V; Cheng PZ; Lee HC; Lane TJ; Hsu TY; Duncan NW · Psychiatry research. Neuroimaging · 2021
    Observational studyMood Support forGABA
  39. Systematic review of gamma-aminobutyric-acid inhibitory deficits across the reproductive life cycle.
    Vigod SN; Strasburg K; Daskalakis ZJ; Blumberger DM · Archives of women's mental health · 2014
    Systematic review11 studies pooledMood Support forGABA
  40. l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
    Shamabadi A; Kafi F; Arab Bafrani M; Asadigandomani H; A Basti F; Akhondzadeh S · Journal of affective disorders · 2023
    Randomized trial60 participantsMood Support forTheanine
  41. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsMood Support Stress Relief forTheanine Stress Relief forGABA
  42. Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.
    Unno K; Tanida N; Ishii N; Yamamoto H; Iguchi K; Hoshino M; Takeda A; Ozawa H; Ohkubo T; Juneja LR; Yamada H · Pharmacology, biochemistry, and behavior · 2014
    Randomized trial20 participantsMood Support forTheanine
  43. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
    Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
    Meta-analysis400 participants5 studies pooledProductivity Boost forAshwagandha
  44. Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
    Langade D; Thakare V; Kanchi S; Kelgane S · Journal of ethnopharmacology · 2021
    Randomized trial80 participantsProductivity Boost Sleep Support forAshwagandha
  45. Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants.
    Pingali U; Pilli R; Fatima N · Pharmacognosy research · 2014
    Randomized trial20 participantsProductivity Boost forAshwagandha
  46. Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
    Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
    Randomized trial120 participantsProductivity Boost forAshwagandha
  47. Effects of L-theanine on cognition, mood and sleep: evidence from human trials.
    Cotter J; Kilpatrick HE · Frontiers in nutrition · 2026
    Narrative reviewProductivity Boost forTheanine
  48. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults.
    Deshpande A; Irani N; Balkrishnan R; Benny IR · Sleep medicine · 2021
    Randomized trial150 participantsSleep Support forAshwagandha
  49. Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial.
    Thanawala S; Shah R; Alluri KV; Bhupathiraju K; Desomayanandanam P; Bhuvenendran A · Medicine · 2026
    Randomized trial135 participantsSleep Support forAshwagandha
  50. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study.
    Langade D; Kanchi S; Salve J; Debnath K; Ambegaokar D · Cureus · 2020
    Randomized trial60 participantsSleep Support forAshwagandha
  51. Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
    Byun JI; Shin YY; Chung SE; Shin WC · Journal of clinical neurology (Seoul, Korea) · 2020
    Randomized trial40 participantsSleep Support forGABA
  52. Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.
    Imafuku F; Yamamoto K; Tanaka E; Aoki R; Nishino S · Nutrients · 2023
    Randomized trial160 participantsSleep Support forGABA
  53. Reduced γ-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: a link to major depressive disorder?
    Plante DT; Jensen JE; Schoerning L; Winkelman JW · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
    Case-control study40 participantsSleep Support forGABA
  54. GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
    Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
    Randomized trial30 participantsSleep Support Stress Relief forGABA
  55. Comparison Between Efficacy of Oral Melatonin and Oral L-theanine in Improving Sleep in Cancer Patients Suffering From Insomnia: A Randomised Double-blinded Placebo-controlled Study.
    Kurdi MS; As A; Ladhad DA; Mitragotri MV; Baiju A · Indian journal of palliative care · 2024
    Randomized trial120 participantsSleep Support forTheanine
  56. The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis.
    Bulman A; D'Cunha NM; Marx W; Turner M; McKune A; Naumovski N · Sleep medicine reviews · 2025
    Meta-analysis897 participants19 studies pooledSleep Support forTheanine
  57. In Search of a Safe Natural Sleep Aid.
    Rao TP; Ozeki M; Juneja LR · Journal of the American College of Nutrition · 2016
    Narrative reviewSleep Support forTheanine
  58. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
    Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
    Randomized trial60 participantsStress Relief forAshwagandha
  59. Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
    Mishra DN; Kumar M · Heliyon · 2024
    Randomized trial60 participantsStress Relief forAshwagandha
  60. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
    Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
    Randomized trial60 participantsStress Relief forAshwagandha
  61. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
    Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H · Journal of nutritional science and vitaminology · 2011
    Clinical trial30 participantsStress Relief forGABA
  62. Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality.
    Meyerhoff DJ; Mon A; Metzler T; Neylan TC · Sleep · 2014
    Case-control study45 participantsStress Relief forGABA
  63. Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.
    White DJ; de Klerk S; Woods W; Gondalia S; Noonan C; Scholey AB · Nutrients · 2016
    Randomized trial34 participantsStress Relief forTheanine