Product Image

Ultra Strength Goodbye Stress

OLLY
4.3
★ ★ ★ ★ ★
(11971 ratings)
Theanine 100 mg
GABA 100 mg
Ashwagandha 125 mg
Product Image
Score75
A practical, transparent calming softgel with a coherent blend, though extract quality details are limited.
How scoring works
Quantity:60 Softgel(s) • (30 servings)
Goals:
Stress Relief
Sleep Support
Mood Support
Productivity Boost
Cognitive Support
Brain Health
Mental Focus

Score 75

A practical, transparent calming softgel with a coherent blend, though extract quality details are limited.
How scoring works
$19.99($0.66 per serving)
Vitacost
$ 20.49
iHerb
$ 19.99
Walmart
$ 19.99
Amazon
$ 19.99
Report prices

Analysis

Theanine and GABA provide direct calming support at moderate amounts. Ashwagandha and lemon balm broaden the formula with botanical stress and relaxation pathways.

The active design is focused and does not hide ingredients in a proprietary blend. Ashwagandha standardization and fuller extract details are missing, limiting comparison with better-characterized formulas.

The softgel serving is convenient and reasonably valued. Strong aggregate feedback does not establish effectiveness, but it supports some confidence in the product experience.

Who is it for
  • Adults seeking everyday stress support
  • People who prefer softgels
  • Users avoiding melatonin
Best for
  • Daytime calm
  • Evening relaxation
  • Stress-related tension

Pros

  • Clear amounts for all actives
  • Coherent four-ingredient formula
  • Convenient softgel format

Cons

  • Ashwagandha standardization is not supplied
  • May be too calming for some daytime users
  • No magnesium or broader sleep nutrients

Warnings

  • The combined calming ingredients may cause drowsiness
  • Ashwagandha may affect thyroid function and warrants caution with thyroid medicine
  • Avoid combining with alcohol or sedatives until individual response is known

Nutrient quality

81 Highest impact

The four ingredients form a coherent and conservatively dosed calming blend. Missing standardization and modest amounts limit potency.

.

Ingredient transparency

82 Highest impact

Active names and doses are clearly disclosed. Non-active ingredients and complete usage directions remain missing.

.

Customer satisfaction

64 Moderate impact

The supplied average rating is mixed. No specific review comments were supplied, so repeated negative experiences cannot be assessed.

.

Value for money

69 High impact

A concise formula provides reasonable everyday utility. Modest doses and mixed aggregate satisfaction limit competitiveness.

.
Report analysis

Goals

Stress Relief
Stress Relief
Impact
Highest effect
A Goal FitB Strength of SupportA- CoverageA+ Formula Quality
Ashwagandha · 125 mgGABA · 100 mgTheanine · 100 mg

OLLY Ultra Strength Goodbye Stress has a supplied customer average of 4.32 from 11831 reviews, and NSF finished-product certification is reported in the prior collection research.

The ashwagandha, GABA, L-theanine, and lemon-balm combination is highly aligned with stress relief, while calming effects may add to sedatives or alcohol, and ashwagandha has pregnancy, thyroid, autoimmune, liver, and medication cautions.

Study evidence
Ashwagandha Supportive 47 studies
GABA Supportive 6 studies
Theanine Supportive 16 studies
Sleep Support
Sleep Support
Impact
Highest effect
A+ Goal FitB- Strength of SupportB+ CoverageA- Formula Quality
Theanine · 100 mg

Ultra Strength Goodbye Stress from OLLY covers circadian regulation, nervous-system relaxation, mineral or physical relaxation support, producing strong alignment with sleep support.

Collection-specific evidence indicates moderate dose adequacy and good form or disclosure quality, with the main limitation being variable evidence across the included calming actives.

Study evidence
Ashwagandha Supportive 18 studies
GABA Supportive 4 studies
Theanine Supportive 8 studies
Mood Support
Mood Support
Impact
Highest effect
B Goal FitB+ Strength of SupportB CoverageA Formula Quality
Ashwagandha · 125 mg

Ultra Strength Goodbye Stress appears best understood as a purpose-built multi-pathway stress formula, and the configured scores reflect that degree of Mood Support alignment.

Supplied customer feedback averages 4.32 from 11,831 reviews; combined calming effects may impair alertness, and ashwagandha still carries thyroid-related cautions.

Study evidence
Ashwagandha Supportive 29 studies
GABA Supportive 12 studies
Theanine Supportive 12 studies
Productivity Boost
Productivity Boost
Impact
High effect
B Goal FitB- Strength of SupportC+ CoverageB Formula Quality
Theanine · 100 mg

Ultra Strength Goodbye Stress aligns with Productivity Boost mainly through Ashwagandha and Theanine, while the supplied collection analyses average 62.8 and supplied customer feedback is 4.32 from 11,831 reviews.

Its strongest feature is dose adequacy, while coverage remains intentionally narrow; it appears better suited to a targeted role within a broader routine.

Study evidence
Ashwagandha Supportive 6 studies
Theanine Supportive 5 studies
Cognitive Support
Cognitive Support
Impact
High effect
C+ Goal FitB- Strength of SupportC CoverageB+ Formula Quality
Ashwagandha · 125 mgTheanine · 100 mg

Ultra Strength Goodbye Stress pairs 100 mg L-theanine with 125 mg ashwagandha for calm-focus support, but the formula remains narrow and stress-oriented.

Customer feedback averages 4.32 from 11831 reviews; The multi-ingredient label and possible sedative, stimulant, or medication interactions deserve review.

Study evidence
Ashwagandha Supportive 17 studies
Theanine Supportive 25 studies
Brain Health
Brain Health
Impact
High effect
C+ Goal FitB- Strength of SupportC+ CoverageB Formula Quality
Ashwagandha · 125 mg

Ultra Strength Goodbye Stress may support mental resilience or cognition through its disclosed actives, with the strength of alignment depending on direct cognitive ingredients and form quality.

The dose and formula structure support a moderate contribution, while evidence quality and pathway coverage remain the main constraints.

Study evidence
Ashwagandha Supportive 12 studies
Theanine Supportive 17 studies
Mental Focus
Mental Focus
Impact
High effect
D+ Goal FitB- Strength of SupportC+ CoverageB Formula Quality
Theanine · 100 mg

Ultra Strength Goodbye Stress uses L-theanine, ashwagandha, and GABA to support calm attention, stress resilience, and calming.

11,831 supplied reviews average 4.32, while the focus mechanism remains indirect.

Study evidence
Ashwagandha Supportive 12 studies
Theanine Supportive 19 studies

Ingredients

IngredientAmount per serving
Calories
5 Calorie(s)
Total Fat
0.5 Gram(s)
Ashwagandha extract
125 mg
GABA
100 mg
L-Theanine
100 mg
Lemon Balm extract
75 mg
Gluten Free Adults 18–50
Report overview
Theanine · 100 mg OverallScore79
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Ultra Strength Goodbye Stress provides 100 mg of clearly disclosed L-theanine, placing the dose in the rubric's optimal tier. Customer satisfaction is favorable at 4.32 from 11831 reviews, and Ultra Goodbye Stress is listed by NSF as a certified finished product. Ashwagandha, GABA, and lemon balm may add calming effects, so users should watch for unwanted drowsiness or medication overlap.

View ingredientView products
GABA · 100 mg OverallScore70
B- Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyD- Value

Ultra Strength Goodbye Stress provides 100 mg of clearly disclosed GABA in easy-to-swallow softgels and has a very large customer-review base, though experiences with the ashwagandha component vary. The GABA is unbranded, and a $0.66 serving price remains high for a standard 100 mg source; people using medicines or managing thyroid, pregnancy, or sedation concerns should review the full formula carefully.

View ingredientView products
Ashwagandha · 125 mg OverallScore46
F Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyF Value

Ultra Strength Goodbye Stress provides 125 mg of generic ashwagandha extract without a stated marker percentage at $0.66 per serving, with 4.32 from 11,831 supplied reviews. NCCIH notes possible stomach upset, drowsiness, rare liver injury, medication interactions, and avoidance during pregnancy or breastfeeding.

View ingredientView products
Loading alternative details
78 Performance

Serenelle

Quality Of Life
<p>Sensoril, 200 mg of theanine, 125 mg of PharmaGABA, and 300 mg of lemon balm provide stronger forms and amounts across the same calming ingredients. The serving costs more, but the formulation is more substantial.</p>
83 Performance

ZenMind

NutriCology
<p>Suntheanine at 200 mg and GABA at 550 mg deliver much higher amounts of two shared calming ingredients. Ashwagandha and lemon balm are absent, while the stronger calming load may increase drowsiness.</p>
73 Performance

SharpMind Stress

Solaray
<p>Standardized Shoden ashwagandha and 200 mg of theanine strengthen ingredient quality and calm-focus support while matching the original GABA amount. Shiitake has unclear practical value, and complete directions and excipients were not supplied.</p>
86 Budget

Anxiety & Stress Relief

Nature's Bounty
<p>Lower serving cost provides 600 mg of ashwagandha extract and 200 mg of theanine, well above the original amounts. GABA and lemon balm are omitted, but the concentrated two-ingredient formula is easier to assess.</p>
83 Budget

GABA Soothe

Jarrow Formulas
<p>Lower serving cost retains ashwagandha, GABA, and theanine in a concise formula. Sensoril is supplied at 225 mg, while GABA and theanine match the original 100 mg amounts.</p>
79 Budget

Superior Sleep

Doctor's Best
<p>Lower serving cost includes Sensoril, 200 mg of theanine, 100 mg of GABA, melatonin, and 5-HTP for stronger nighttime coverage. The sleep additions may cause morning grogginess and require care with serotonergic medicines.</p>
62 Value

Stress Relief Plus

EB Earth's Bounty
<p>Slightly lower serving cost provides Sensoril ashwagandha, 200 mg of theanine, and magnesium citrate for broader stress support. A proprietary herbal blend and relatively high vitamin B6 and chromium amounts weaken transparency and suitability.</p>
74 Value

Chewable GABA

NOW
<p>Much lower serving cost and 500 mg of GABA create a strong value option for users prioritizing that ingredient. Ashwagandha and lemon balm are absent, and theanine is only 20 mg, so it is less complete.</p>
79 Value

Relax Magnesium Powder Berry

youtheory
<p>Comparable serving value combines 300 mg of magnesium citrate with the same 100 mg amounts of theanine and GABA. It omits ashwagandha and lemon balm, but the ingredient amounts are clearly stated and purposeful.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
    Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
    Randomized trial60 participantsStress Relief forAshwagandha
  2. Dual impact of Ashwagandha: Significant cortisol reduction but no effects on perceived stress - A systematic review and meta-analysis.
    Albalawi AA · Nutrition and health · 2025
    Meta-analysis488 participants13 studies pooledStress Relief forAshwagandha
  3. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
    Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
    Randomized trial63 participantsStress Relief Mood Support forGABA
  4. Effect of Combined Ingestion of L-Theanine and L-Arginine for Short-Term Psychological Stress in Young Adults: A Randomized Placebo-Controlled Study.
    Furushima D; Sugiyama I; Nomura Y; Unno K; Yamada H · Journal of nutritional science and vitaminology · 2023
    Randomized trial120 participantsStress Relief forTheanine
  5. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
    Sarris J; Byrne GJ; Cribb L; Oliver G; Murphy J; Macdonald P; Nazareth S; Karamacoska D; Galea S; Short A; Ee C; Birling Y; Menon R; Ng CH · Journal of psychiatric research · 2020
    Randomized trial46 participantsStress Relief Sleep Support forTheanine
  6. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsBrain Health Cognitive Support forAshwagandha
  7. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsBrain Health Cognitive Support Mental Focus forAshwagandha
  8. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsBrain Health Cognitive Support Productivity Boost forAshwagandha
  9. A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
    Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
    Randomized trial85 participantsBrain Health Mental Focus forAshwagandha
  10. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
    Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
    Randomized trial130 participantsBrain Health Sleep Support Stress Relief forAshwagandha
  11. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsBrain Health Cognitive Support Sleep Support forTheanine
  12. A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
    Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
    Randomized trialBrain Health Stress Relief forTheanine
  13. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B · Nutrition reviews · 2025
    Meta-analysis50 studies pooledBrain Health Cognitive Support Mental Focus forTheanine
  14. Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
    Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP · Neuropharmacology · 2012
    Randomized trial27 participantsBrain Health Cognitive Support forTheanine
  15. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
    Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T · Journal of medicinal food · 2021
    Randomized trialBrain Health Mental Focus Productivity Boost forTheanine
  16. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
    Randomized trial54 participantsCognitive Support Mental Focus forAshwagandha
  17. Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
    Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
    Randomized trial58 participantsCognitive Support Mental Focus forAshwagandha
  18. Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study.
    Dassanayake TL; Wijesundara D; Kahathuduwa CN; Weerasinghe VS · Nutritional neuroscience · 2023
    Randomized trial32 participantsCognitive Support forTheanine
  19. Acute effects of theanine, caffeine and theanine-caffeine combination on attention.
    Kahathuduwa CN; Dassanayake TL; Amarakoon AMT; Weerasinghe VS · Nutritional neuroscience · 2018
    Clinical trial20 participantsCognitive Support Mental Focus forTheanine
  20. Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.
    Choudhary D; Bhattacharyya S; Bose S · Journal of dietary supplements · 2018
    Randomized trial50 participantsMental Focus forAshwagandha
  21. Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED · Neurology and therapy · 2024
    Randomized trial30 participantsMental Focus Productivity Boost Stress Relief forTheanine
  22. Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study.
    Karunaratne UW; Dassanayake TL · Nutritional neuroscience · 2025
    Randomized trial24 participantsMental Focus forTheanine
  23. A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.
    West RE; Biswas A; Rao R; Tayade H; Ademola J · Journal of medicine and life · 2026
    Randomized trial141 participantsMood Support forAshwagandha
  24. Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
    Fatima K; Malik J; Muskan F; Raza G; Waseem A; Shahid H; Jaffery SF; Khan U; Zaheer MK; Shaikh Y; Rashid AM · Human psychopharmacology · 2024
    Meta-analysis254 participants5 studies pooledMood Support forAshwagandha
  25. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
    Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
    Randomized trial64 participantsMood Support Stress Relief forAshwagandha
  26. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
    McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
    Randomized trial186 participantsMood Support forAshwagandha
  27. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
    Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
    Meta-analysis29 participants29 studies pooledMood Support forAshwagandha
  28. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
    Deligiannidis KM; Kroll-Desrosiers AR; Mo S; Nguyen HP; Svenson A; Jaitly N; Hall JE; Barton BA; Rothschild AJ; Shaffer SA · Psychoneuroendocrinology · 2017
    Cohort study56 participantsMood Support forGABA
  29. The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
    Wang J; Liu G; Xu K; Ai K; Huang W; Zhang J · Human brain mapping · 2023
    Case-control study69 participantsMood Support forGABA
  30. Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis.
    Truong V; Cheng PZ; Lee HC; Lane TJ; Hsu TY; Duncan NW · Psychiatry research. Neuroimaging · 2021
    Observational studyMood Support forGABA
  31. Systematic review of gamma-aminobutyric-acid inhibitory deficits across the reproductive life cycle.
    Vigod SN; Strasburg K; Daskalakis ZJ; Blumberger DM · Archives of women's mental health · 2014
    Systematic review11 studies pooledMood Support forGABA
  32. l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
    Shamabadi A; Kafi F; Arab Bafrani M; Asadigandomani H; A Basti F; Akhondzadeh S · Journal of affective disorders · 2023
    Randomized trial60 participantsMood Support forTheanine
  33. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
    Ritsner MS; Miodownik C; Ratner Y; Shleifer T; Mar M; Pintov L; Lerner V · The Journal of clinical psychiatry · 2011
    Randomized trial60 participantsMood Support Stress Relief forTheanine
  34. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.
    Williams JL; Everett JM; D'Cunha NM; Sergi D; Georgousopoulou EN; Keegan RJ; McKune AJ; Mellor DD; Anstice N; Naumovski N · Plant foods for human nutrition (Dordrecht, Netherlands) · 2020
    Systematic review9 studies pooledMood Support forTheanine
  35. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsMood Support Stress Relief forTheanine Stress Relief forGABA
  36. Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.
    Unno K; Tanida N; Ishii N; Yamamoto H; Iguchi K; Hoshino M; Takeda A; Ozawa H; Ohkubo T; Juneja LR; Yamada H · Pharmacology, biochemistry, and behavior · 2014
    Randomized trial20 participantsMood Support forTheanine
  37. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
    Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
    Meta-analysis400 participants5 studies pooledProductivity Boost forAshwagandha
  38. Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
    Langade D; Thakare V; Kanchi S; Kelgane S · Journal of ethnopharmacology · 2021
    Randomized trial80 participantsProductivity Boost Sleep Support forAshwagandha
  39. Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants.
    Pingali U; Pilli R; Fatima N · Pharmacognosy research · 2014
    Randomized trial20 participantsProductivity Boost forAshwagandha
  40. Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
    Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
    Randomized trial120 participantsProductivity Boost forAshwagandha
  41. Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials.
    Gerolymos C; Saddier E; Boyer L; Fond G · Molecular psychiatry · 2026
    Meta-analysis1,168 participants31 studies pooledProductivity Boost forTheanine
  42. Effects of L-theanine on cognition, mood and sleep: evidence from human trials.
    Cotter J; Kilpatrick HE · Frontiers in nutrition · 2026
    Narrative reviewProductivity Boost forTheanine
  43. Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.
    Rogers PJ; Smith JE; Heatherley SV; Pleydell-Pearce CW · Psychopharmacology · 2008
    Randomized trial48 participantsProductivity Boost forTheanine
  44. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults.
    Deshpande A; Irani N; Balkrishnan R; Benny IR · Sleep medicine · 2021
    Randomized trial150 participantsSleep Support forAshwagandha
  45. Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial.
    Thanawala S; Shah R; Alluri KV; Bhupathiraju K; Desomayanandanam P; Bhuvenendran A · Medicine · 2026
    Randomized trial135 participantsSleep Support forAshwagandha
  46. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study.
    Langade D; Kanchi S; Salve J; Debnath K; Ambegaokar D · Cureus · 2020
    Randomized trial60 participantsSleep Support forAshwagandha
  47. Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
    Byun JI; Shin YY; Chung SE; Shin WC · Journal of clinical neurology (Seoul, Korea) · 2020
    Randomized trial40 participantsSleep Support forGABA
  48. Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.
    Imafuku F; Yamamoto K; Tanaka E; Aoki R; Nishino S · Nutrients · 2023
    Randomized trial160 participantsSleep Support forGABA
  49. Reduced γ-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: a link to major depressive disorder?
    Plante DT; Jensen JE; Schoerning L; Winkelman JW · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
    Case-control study40 participantsSleep Support forGABA
  50. GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
    Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
    Randomized trial30 participantsSleep Support Stress Relief forGABA
  51. Comparison Between Efficacy of Oral Melatonin and Oral L-theanine in Improving Sleep in Cancer Patients Suffering From Insomnia: A Randomised Double-blinded Placebo-controlled Study.
    Kurdi MS; As A; Ladhad DA; Mitragotri MV; Baiju A · Indian journal of palliative care · 2024
    Randomized trial120 participantsSleep Support forTheanine
  52. The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis.
    Bulman A; D'Cunha NM; Marx W; Turner M; McKune A; Naumovski N · Sleep medicine reviews · 2025
    Meta-analysis897 participants19 studies pooledSleep Support forTheanine
  53. In Search of a Safe Natural Sleep Aid.
    Rao TP; Ozeki M; Juneja LR · Journal of the American College of Nutrition · 2016
    Narrative reviewSleep Support forTheanine
  54. Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
    Mishra DN; Kumar M · Heliyon · 2024
    Randomized trial60 participantsStress Relief forAshwagandha
  55. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
    Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
    Randomized trial60 participantsStress Relief forAshwagandha
  56. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
    Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H · Journal of nutritional science and vitaminology · 2011
    Clinical trial30 participantsStress Relief forGABA
  57. Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality.
    Meyerhoff DJ; Mon A; Metzler T; Neylan TC · Sleep · 2014
    Case-control study45 participantsStress Relief forGABA
  58. Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.
    White DJ; de Klerk S; Woods W; Gondalia S; Noonan C; Scholey AB · Nutrients · 2016
    Randomized trial34 participantsStress Relief forTheanine