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Niacinamide 500 mg

Nature's Way
4.6
★ ★ ★ ★ ★
(2957 ratings)
Niacin 500 mg
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Score81
A strong-value, transparent niacinamide capsule with focused skin relevance, balanced by narrow coverage and high-dose safety considerations.
How scoring works
Quantity:100 Capsule(s) • (100 servings)
Goals:
Skin Health

Score 81

A strong-value, transparent niacinamide capsule with focused skin relevance, balanced by narrow coverage and high-dose safety considerations.
How scoring works
$9.99($0.09 per serving)
Vitacost
$ 9.99
Vitacost
$ 9.99
Pure Formulas
$ 9.99
iHerb
$ 9.99
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Analysis

Niacinamide supports cellular energy and may contribute to skin-barrier metabolism without the flushing associated with nicotinic acid. The exact form and substantial amount are clearly stated.

The single ingredient cannot provide collagen, hydration, or broad antioxidant coverage for skin. It also does not produce the lipid effects expected from nicotinic acid.

The low serving cost suits adults who specifically want oral niacinamide. People using it long term should consider liver health, digestive tolerance, and total intake from other B3 products.

Who is it for
  • Adults seeking a non-flushing B3 form
  • Value-focused niacinamide users
  • People wanting a simple capsule
Best for
  • Focused niacinamide supplementation
  • Skin-barrier nutrient support
  • Cellular energy metabolism

Pros

  • Chemical form is explicit
  • Strong practical value
  • Simple single-ingredient formula

Cons

  • No structural skin ingredients
  • Weak cardiovascular alignment
  • Amount exceeds routine nutritional needs

Warnings

  • The large niacinamide amount may cause nausea or digestive effects
  • People with significant liver disease should seek guidance before regular use
  • Long-term high intake may affect glucose control in susceptible users

Nutrient quality

75 High impact

Niacinamide is a usable non-flushing vitamin B3 form supplied well above nutritional requirements. Its heart-health fit is limited, and the elevated amount reduces balance for routine use.

Ingredient transparency

87 Highest impact

The active amount and serving size are clear, with no proprietary blend hiding the formula. Non-active ingredients and complete usage directions are not supplied.

Customer satisfaction

70 High impact

The average rating is strong, with a large review count supporting the signal. No detailed reviews are supplied to assess repeated complaints or intended-use experiences.

Value for money

91 Highest impact

The simple formula and long supply provide good practical value. The elevated amount remains less suitable for users who need only basic vitamin B3 intake.

Report analysis

Goals

Skin Health
Impact
High effect
C Goal FitA- Strength of SupportD CoverageA+ Formula Quality

Niacinamide supports cellular energy and skin-barrier biology, but oral use is less directly supported than topical application for common skin goals. The 500 mg amount is substantial and clearly disclosed.

A standalone capsule cannot cover collagen structure, hydration, or a broad antioxidant network. At this high oral amount, niacinamide may cause nausea or other digestive effects and warrants caution with significant liver disease.

Study evidence
Niacin Supportive 61 studies

Ingredients

IngredientAmount per serving
Niacin (Niacinamide)
500 mg
Gluten Free Adults 18–50 Vegan Dairy Free Women Vegetarian
Report overview
A Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value

A clearly labeled 500 mg niacinamide dose fits skin and general niacin use without the classic niacin flush. The capsule has standard immediate delivery and no unnecessary precursor claims. The very low serving cost creates strong value.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of Nicotinamide in Skin Cancer and Actinic Keratoses Chemoprophylaxis, and Adverse Effects Related to Nicotinamide: A Systematic Review and Meta-Analysis.
    Mainville L; Smilga AS; Fortin PR · Journal of cutaneous medicine and surgery · 2022
    Meta-analysis3,039 participants29 studies pooledSkin Health forNiacin
  2. Nicotinamide for Skin-Cancer Chemoprevention in Transplant Recipients.
    Allen NC; Martin AJ; Snaidr VA; Eggins R; Chong AH; Fernandéz-Peñas P; Gin D; Sidhu S; Paddon VL; Banney LA; Lim A; Upjohn E; Schaider H; Ganhewa AD; Nguyen J; McKenzie CA; Prakash S; McLean C; Lochhead A; Ibbetson J; Dettrick A; Landgren A; Allnutt KJ; Allison C; Davenport RB; Mumford BP; Wong B; Stagg B; Tedman A; Gribbin H; Edwards HA; De Rosa N; Stewart T; Doolan BJ; Kok Y; Simpson K; Low ZM; Kovitwanichkanont T; Scolyer RA; Dhillon HM; Vardy JL; Chadban SJ; Bowen DG; Chen AC; Damian DL · The New England journal of medicine · 2023
    Randomized trial158 participantsSkin Health forNiacin
  3. A Foodborne Outbreak Traced to Niacin Overenrichment.
    Hudson PJ; Vogt RL · Journal of food protection · 2023
    Case-control study21 participantsSkin Health forNiacin
  4. The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparative trial.
    Chiu PC; Chan CC; Lin HM; Chiu HC · Journal of cosmetic dermatology · 2008
    Randomized trial52 participantsSkin Health forNiacin
  5. The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.
    Hakozaki T; Minwalla L; Zhuang J; Chhoa M; Matsubara A; Miyamoto K; Greatens A; Hillebrand GG; Bissett DL; Boissy RE · The British journal of dermatology · 2002
    Randomized trial138 participantsSkin Health forNiacin
  6. Niacinamide: A B vitamin that improves aging facial skin appearance.
    Bissett DL; Oblong JE; Berge CA · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2005
    Randomized trial50 participantsSkin Health forNiacin
  7. Nicotinamide for Skin Cancer Chemoprevention.
    Breglio KF; Knox KM; Hwang J; Weiss R; Maas K; Zhang S; Yao L; Madden C; Xu Y; Hartman RI; Wheless L · JAMA dermatology · 2025
    Cohort study33,822 participantsSkin Health forNiacin
  8. Niacin intake and risk of skin cancer in US women and men.
    Park SM; Li T; Wu S; Li WQ; Weinstock M; Qureshi AA; Cho E · International journal of cancer · 2017
    Cohort study114,116 participantsSkin Health forNiacin
  9. Evaluation of anti-wrinkle effects of a novel cosmetic containing niacinamide.
    Kawada A; Konishi N; Oiso N; Kawara S; Date A · The Journal of dermatology · 2008
    Randomized trial30 participantsSkin Health forNiacin
  10. Chemoprevention of keratinocyte carcinomas and actinic keratoses in adults who were immunocompetent: a systematic review.
    Susanto A; Morgan E; Lindsay D; Collins LG · Clinical and experimental dermatology · 2026
    Systematic review7,355 participants11 studies pooledSkin Health forNiacin
  11. A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention.
    Chen AC; Martin AJ; Choy B; Fernández-Peñas P; Dalziell RA; McKenzie CA; Scolyer RA; Dhillon HM; Vardy JL; Kricker A; St George G; Chinniah N; Halliday GM; Damian DL · The New England journal of medicine · 2015
    Randomized trial386 participantsSkin Health forNiacin