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Liver Detox

Protocol For Life Balance
4.9
★ ★ ★ ★ ★
(2715 ratings)
Methionine
L-Carnitine 50 mg
Gluthathione 100 mg
Milk Thistle 300 mg
Turmeric 30 mg
Product Image
Score59
A credible milk-thistle and antioxidant formula, weakened by light extras, hidden enzymes, and modest value.
How scoring works
Quantity:90 Capsule(s) • (30 servings)
Goals:
Detoxification

Score 59

A credible milk-thistle and antioxidant formula, weakened by light extras, hidden enzymes, and modest value.
How scoring works
$26.00($0.86 per serving)
Pure Formulas
$ 28.00
Amazon
$ 26.00
Vitacost
$ 28.00
iHerb
$ 28.00
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Analysis

Milk thistle is the strongest active and is supported by NAC, reduced glutathione, grape-seed extract, and alpha-lipoic acid. Together they provide several antioxidant and glutathione-related pathways.

Schisandra is relevant, but carnitine, turmeric, methionine, and barberry appear at light amounts. The herbal-enzyme blend lacks component names and activity units.

The formula is broad but relatively expensive for its modest supporting doses. A simpler product may be easier to assess for users focused on one liver-support ingredient.

Who is it for
  • Adults seeking broad liver-support nutrients
  • Users who prefer milk thistle with NAC and glutathione
  • People comfortable with multi-botanical formulas
Best for
  • Milk-thistle supplementation
  • Antioxidant support
  • Detoxification-oriented routines

Pros

  • Substantial named milk-thistle extracts
  • Includes reduced glutathione and NAC
  • Several complementary antioxidants

Cons

  • Hidden enzyme-blend contents
  • Many additions are lightly dosed
  • Relatively high serving cost

Warnings

  • Alpha-lipoic acid may lower blood glucose and interact with diabetes medication
  • Barberry makes the formula unsuitable during pregnancy
  • Undisclosed enzyme ingredients limit allergy assessment

Nutrient quality

66 High impact

Standardized milk thistle anchors a coherent liver-support formula. Most supporting actives are modest and an opaque enzyme blend weakens focus.

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Ingredient transparency

54 Moderate impact

Most core active amounts are visible. An undisclosed blend and missing non-active ingredients reduce transparency.

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Customer satisfaction

72 High impact

The supplied average rating is exceptionally strong. No specific review comments were supplied, so repeated negative experiences cannot be assessed.

.

Value for money

43 Lower impact

Standardized milk thistle provides some practical value. High serving cost and a diluted formula reduce competitiveness.

.
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Goals

Detoxification
Detoxification
Impact
High effect
B+ Goal FitD Strength of SupportC+ CoverageC+ Formula Quality
Milk Thistle · 300 mg

Milk thistle, NAC, reduced glutathione, and alpha-lipoic acid make the formula directly relevant to liver protection and antioxidant recycling. The active mix is much more targeted than a general cleanse, but most supporting compounds are supplied at modest amounts.

Milk thistle is not standardized to a stated silymarin percentage, so its active dose cannot be confirmed. Several small botanicals add breadth without enough disclosure or dose to show a meaningful contribution.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Carbohydrates
1 Gram(s)
Milk Thistle Extract (Milk Thistle Fruit Extract, Milk Thistle Seed Extract)
 300 mg
Herbal-Enzyme Blend
90 mg
L-Glutathione, Reduced
100 mg
N-Acetyl Cysteine
100 mg
Grape Seed Extract (Polyphenols)
 100 mg
Alpha Lipoic Acid
100 mg
L-Carnitine (L-Carnitine Tartrate)
 50 mg
Scute
50 mg
Schisandra
100 mg
Barberry
30 mg
Turmeric
30 mg
L-Methionine
20 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Methionine · 20 mg OverallScore58
A- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyD- Value

The preferred L-form is clearly disclosed, but the amount is too low for focused methionine supplementation. No formal purity grade or branded amino acid source is stated. The above-midpoint serving cost may reflect the wider liver-support formula rather than meaningful methionine value.

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L-Carnitine (L-Carnitine Tartrate) · 50 mg OverallScore44
B- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

L-carnitine tartrate is a suitable form for fitness support, but its amount is far too low to anchor an L-carnitine supplement. The label does not state elemental yield or identify a quality-controlled branded source. The formula is primarily a liver-support blend, leaving very poor value for shoppers focused on carnitine.

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Gluthathione · 100 mg OverallScore40
D- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyD- Value

Reduced L-glutathione provides a recognized active form, but no branded source or purity claim is disclosed. The clearly listed amount is a maintenance-level dose rather than a high-potency serving. Its above-median serving cost limits glutathione-specific value within the broader liver formula.

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Loading alternative details
69 Performance

Liver Detox & Blood Refresh

Irwin Naturals
<p>It is a stronger formulation match because 270 mg of silymarin is paired with vitamin C, selenium, burdock, and dandelion. Compared with the original’s broad but mostly modestly dosed milk-thistle and antioxidant blend, many additional herbs, algae, and powders are too lightly dosed to contribute much, and cayenne may aggravate reflux.</p>
74 Performance

Active Liver

New Nordic
<p>It is a stronger formulation match because 250 mg of milk-thistle extract is paired with 222 mg of artichoke and 150 mg of turmeric. Compared with the original’s broad but mostly modestly dosed milk-thistle and antioxidant blend, the extract weights are useful, but active-marker yields are not supplied.</p>
77 Performance

Liver Support Factors

Country Life
<p>It is a stronger formulation match because 400 mg of methionine is paired with choline, milk thistle, artichoke, and turmeric. Compared with the original’s broad but mostly modestly dosed milk-thistle and antioxidant blend, most botanical extracts lack active-marker standardization and several companion amounts are modest.</p>
66 Budget

Advanced Liver Support

Super Nutrition
<p>It is a more economical option because paired milk-thistle fruit and seed extracts are supported by 100 mg each of glutathione, NAC, grape polyphenols, and alpha-lipoic acid. Compared with the original’s broad but mostly modestly dosed milk-thistle and antioxidant blend, the enzyme blend is hidden and many secondary additions are modestly dosed.</p>
80 Budget

Silymarin Complex

California Gold Nutrition
<p>It is a more economical option because 300 mg of milk thistle is paired with dandelion, artichoke, turmeric, ginger, and piperine. Compared with the original’s broad but mostly modestly dosed milk-thistle and antioxidant blend, the active silymarin yield is not supplied and the supporting botanicals remain modest.</p>
81 Budget

Milk Thistle Phytosome 150 mg

Natural Factors HerbalFactors
<p>It is a more economical option because a 150 mg milk-thistle phytosome is paired with dandelion, turmeric, and artichoke. Compared with the original’s broad but mostly modestly dosed milk-thistle and antioxidant blend, the phytosome improves the absorption case, although the active silymarin yield is not supplied.</p>
65 Value

Super Thisilyn

Nature's Way
<p>It offers a useful quality-to-cost balance because 175 mg of milk thistle is paired with artichoke, NAC, methionine, turmeric, and alpha-lipoic acid. Compared with Liver Detox, milk-thistle potency is unclear and the proprietary vegetable blend reduces transparency.</p>
63 Value

Liver Refresh

NOW
<p>It offers a useful quality-to-cost balance because 300 mg of milk-thistle flavonoids is paired with 100 mg each of glutathione, NAC, grape polyphenols, and alpha-lipoic acid. Compared with Liver Detox, the enzyme blend is hidden and many additional herbs and amino acids are modestly dosed.</p>
79 Value

Silymarin Complex

California Gold Nutrition
<p>It offers a useful quality-to-cost balance because 300 mg of milk thistle is paired with dandelion, artichoke, turmeric, ginger, and piperine. Compared with Liver Detox, the active silymarin yield is not supplied and the smaller herbs add breadth rather than verified potency.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  2. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  3. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  4. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle
  5. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle