Product Image

Vitastack Orange

ALLMAX
4.5
★ ★ ★ ★ ★
(168 ratings)
Manganese 9 mg
Niacin 45 mg
Phosphorus 565 mg
Thiamin 15 mg
Potassium 115 mg
Vitamin C 725 mg
Choline 42 mg
Product Image
Score44
A broad all-in-one powder whose many specialty ingredients are mostly too lightly dosed to matter. Undisclosed caffeine from guarana and high manganese are the biggest drawbacks.
How scoring works
Quantity:250 Gram(s) • (30 servings)
Goals:
Bone Health

Score 44

A broad all-in-one powder whose many specialty ingredients are mostly too lightly dosed to matter. Undisclosed caffeine from guarana and high manganese are the biggest drawbacks.
How scoring works
$34.99($1.16 per serving)
iHerb
$ 39.88
Nutrition Faktory
$ 34.99
Report prices

Analysis

A wide nutrient base covers general vitamins, minerals, amino acids, and several antioxidant pathways. Powder delivery may appeal to users who prefer a drink over multiple capsules.

Joint actives and many herbs or enzymes are present only in token amounts, so the long label overstates practical depth. Guarana is included without a disclosed caffeine yield, and manganese and folate are high enough to complicate routine stacking.

The product fits users who want an all-in-one flavored powder and tolerate stimulants. It is a poor match for caffeine-sensitive people or those seeking meaningful joint dosing from a transparent, focused formula.

Who is it for
  • Adults who prefer powdered multinutrients
  • Stimulant-tolerant users
  • People seeking broad rather than focused coverage
Best for
  • Drink-based micronutrient coverage
  • Broad general nutrition
  • Users who value convenience over formula simplicity

Pros

  • Wide vitamin and mineral coverage
  • Includes amino acids, herbs, and enzymes
  • Powder format avoids a large tablet burden

Cons

  • Many specialty ingredients appear at token doses
  • Caffeine yield from guarana is not disclosed
  • Joint actives are too small for focused support

Warnings

  • Guarana supplies caffeine, but the amount is not disclosed; caffeine-sensitive users should avoid assuming it is stimulant-free.
  • The high manganese amount can become excessive when combined with other mineral supplements.
  • High folate intake may be inappropriate when stacked with fortified foods or another high-dose multivitamin.

Nutrient quality

44 Lower impact

Several core nutrients use favorable forms and substantial amounts. Many specialty ingredients are lightly dosed, while several nutrients appear unnecessarily aggressive.

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Ingredient transparency

43 Lower impact

Many individual actives are quantified and several forms are specific. Combined matrices, repeated totals, incomplete directions, and missing inactive ingredients sharply reduce clarity.

.

Customer satisfaction

63 Moderate impact

The supplied average rating is strong. The review count provides useful evidence but is not extensive.

.

Value for money

29 Situational impact

Useful core nutrient forms provide some value. A high serving cost and many lightly dosed extras make the formula inefficient.

.
Report analysis

Goals

Bone Health
Bone Health
Impact
High effect
B+ Goal FitC+ Strength of SupportB- CoverageF Formula Quality
Phosphorus · 565 mgMagnesium · 50 mgCalcium · 775 mgVitamin D · 12 mcgCopper · 0.2 mgManganese · 9 mgBoron · 700 mcgZinc · 10 mgVitamin C · 725 mgGlycine · 50 mg

Calcium, phosphorus, vitamin D3, and vitamin C provide a broad foundation for mineralization and collagen support. Trace minerals extend coverage across several bone-remodeling pathways.

Magnesium and glycine are small relative to the rest of the formula, and several forms are less attractive. The exceptionally crowded blend makes the product unfocused despite its meaningful structural-mineral content.

Study evidence
Calcium Supportive 144 studies
Glycine Disputed 6 studies
Magnesium Supportive 48 studies
Phosphorus Supportive 44 studies
Silicon Supportive 13 studies
Vitamin C Supportive 46 studies
Immunity
Immunity
Impact
Moderate effect
B Goal FitB- Strength of SupportB- CoverageF Formula Quality
Magnesium · 50 mgVitamin C · 725 mgZinc · 10 mgVitamin A · 1500 mcgVitamin D · 12 mcgSelenium · 30 mcg

A substantial vitamin C amount plus vitamins A and D, zinc, selenium, and vitamin E creates very broad immune-related coverage. The powder format and partial mineral buffering make the vitamin C component practical.

Zinc and selenium are modest, while a seventy-plus-ingredient performance blend spreads doses across many unrelated compounds. The crowded design favors label breadth over meaningful depth in the immune pathways.

Study evidence
Selenium Mixed 37 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Vitamin E Supportive 21 studies
Zinc Supportive 73 studies
Skin Health
Skin Health
Impact
Moderate effect
C+ Goal FitC Strength of SupportC+ CoverageD+ Formula Quality
Zinc · 10 mgVitamin C · 725 mgGlycine · 50 mgCopper · 0.2 mgSelenium · 30 mcgSilicon · 40.5 mgVitamin E · 64 mg

A high vitamin C amount, broad vitamin E forms, beta-carotene, zinc, and silicon provide several skin-relevant antioxidant and collagen-cofactor pathways. The powder offers breadth but is designed as an all-purpose performance stack.

Silicon reaches a useful elemental amount, though silicon dioxide has limited absorption and glycine is far too low for structural support. CoQ10 is also token-sized, while guarana adds stimulant exposure unrelated to skin.

Study evidence
Glycine Disputed 2 studies
Silicon Supportive 16 studies
Vitamin C Supportive 53 studies
Vitamin E Supportive 38 studies
Zinc Supportive 66 studies
Nail Health
Nail Health
Impact
Moderate effect
C Goal FitC+ Strength of SupportB- CoverageF Formula Quality
Silicon · 40.5 mgBiotin · 30 mcg

Silica, vitamin C, zinc, biotin, MSM, glycine, and histidine touch several pathways involved in nail structure. Many structural ingredients are lightly dosed, while the extremely broad sports stack devotes most of its formula to unrelated goals.

Most individual amounts and forms are disclosed, including a substantial silica entry, but the enormous ingredient count reduces focus. Guarana adds stimulant exposure, and the shellfish-derived glucosamine ingredients are unsuitable for people with a relevant shellfish allergy.

Study evidence
Biotin Supportive 8 studies
Silicon Supportive 2 studies
Vitamin C Supportive 1 study
Zinc No effect 1 study
General Health
General Health
Impact
Moderate effect
B Goal FitC- Strength of SupportC+ CoverageF Formula Quality
Folate · 1336 mcg DFEVitamin B12 · 27 mcgVitamin D · 12 mcgMagnesium · 50 mgBoron · 700 mcgGlycine · 50 mgSelenium · 30 mcgTaurine · 200 mgZinc · 10 mgVitamin C · 725 mg

A very broad nutrient stack covers vitamins, minerals, amino acids, botanicals, enzymes, and several structural compounds. The formula contains meaningful vitamin C and calcium along with some clearly identified active forms.

Many additional ingredients are present at very small amounts, and repeated full totals across several source forms make true source contributions difficult to interpret. Guarana leaves total caffeine exposure unclear, while shellfish-derived glucosamine makes the powder unsuitable for people with a shellfish allergy.

Study evidence
Vitamin C Supportive 56 studies
Hair Health
Hair Health
Impact
Moderate effect
C- Goal FitC Strength of SupportC- CoverageD+ Formula Quality
Biotin · 30 mcgVitamin D · 12 mcgZinc · 10 mgVitamin C · 725 mg

Silicon, high vitamin C, zinc, amino acids, vitamin D, biotin, selenium, and copper provide structural cofactors and broad follicle nutrition. The silicon amount is promising, but its dioxide form has weak absorption and the amino acids are mostly small.

Vitamin C and listed silicon reach meaningful amounts. Low biotin, modest zinc, poor copper balance, and many performance-oriented extras reduce the depth and focus of the hair support.

Study evidence
Biotin Supportive 4 studies
Copper Adverse 4 studies
Selenium Disputed 7 studies
Silicon Supportive 2 studies
Vitamin C Mixed 5 studies
Vitamin D Disputed 34 studies
Zinc Supportive 22 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene)
 1500 mcg
Vitamin C (Ascorbic Acid, Calcium Ascorbate, Sodium Ascorbate)
 725 mg
Vitamin D (Cholecalciferol)
 12 mcg
Vitamin E (D-Alpha-Tocopheryl Succinate, Tocopherol, Tocotrienols)
 64 mg
Thiamine (Thiamine Hydrochloride, Vitamin B1)
 15 mg
Riboflavin (Vitamin B2)
 2.5 mg
Vitamin B3 (Niacin, Niacinamide)
 45 mg
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Hydrochloride)
 2.5 mg
Folate
1336 mcg DFE
Vitamin B12 (Cyanocobalamin, Methylcobalamin)
 27 mcg
Biotin
30 mcg
Pantothenic Acid (D-Calcium Pantothenate)
 10 mg
Choline (Choline Bitartrate)
 42 mg
Calcium (Calcium Ascorbate, Calcium Glucarate, Dicalcium Phosphate)
 775 mg
Phosphorus (Dicalcium Phosphate, Phosphorus Amino Acid Chelate)
 565 mg
Magnesium (Magnesium Aspartate, Magnesium Oxide)
 50 mg
Zinc (Zinc Aspartate)
 10 mg
Selenium (Selenium Amino Acid Chelate)
 30 mcg
Copper (Copper Amino Acid Chelate)
 0.2 mg
Manganese (Manganese Amino Acid Chelate)
 9 mg
Chromium (Chromium Polynicotinate)
 120 mcg
Potassium (Potassium Aspartate, Potassium Phosphate, Tripotassium Citrate)
 115 mg
Advanced BCAA Matrix
400 mg
L-Taurine
200 mg
L-Tyrosine
200 mg
L-Arginine Hydrochloride
104 mg
Methylsulfonylmethane
100 mg
D-Glucuronolactone
100 mg
Guarana, Powder (Paullinia cupana)
 100 mg
Milk Thistle seed extract (Silymarin)
 100 mg
L-Glutamine
100 mg
Ginseng Root Extract (Panax ginseng Root Concentrate, Panax quinquefolius Root Extract)
 94 mg
Glucosamine HCl (Shellfish)
 79 mg
Glucosamine Sulfate 2KCl (Shellfish)
 79 mg
Inositol
75 mg
Ginkgo biloba Leaf Extract (Ginkgo Flavone Glycosides, Terpene Lactones)
 60 mg
Lipase (Rhizopus oryzae)
 59 mg
Amylase (Aspergillus oryzae)
 52 mg
L-Glycine
50 mg
Protease (Bacillus subtilis)
 45 mg
Chondroitin Sulfate Sodium (Bovine)
 42 mg
Silica (Silicon Dioxide)
 40.5 mg
Red Wine Extract (Vitis vinifera Fruit Extract)
 40 mg
Pomegranate extract (Ellagic Acid)
 33 mg
Rutin
30 mg
Grape seed extract (Proanthocyanidins)
 25 mg
Turmeric extract (Curcuminoids)
 25 mg
L-Histidine Hydrochloride
25 mg
L-Citrulline (L-Citrulline Malate)
 25 mg
Alpha Lipoic Acid
25 mg
Bromelain (Ananas comosus)
 20 mg
Coenzyme Q10 (Ubidecarenone)
 10 mg
Black Pepper Fruit Extract (Piperine)
 2.5 mg
Papain (Carica papaya)
 2 mg
Boron (Boron Amino Acid Chelate)
 700 mcg
Adults 18–50
Report overview
Manganese (Manganese Amino Acid Chelate) · 9 mg OverallScore84
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

An amino acid chelate provides a high-quality manganese form with good absorption potential. The 9 mg amount is clearly disclosed and falls within the preferred range without exceeding the upper limit. The serving is expensive when judged for manganese value.

View ingredientView products
Niacin (Niacinamide) · 45 mg OverallScore74
B+ Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyC Value

A blend of niacin and niacinamide fits the broad multinutrient design, with an amount aligned to common multivitamin use. Powder delivery is immediate and offers no specialized release control, while one niacin form remains imprecise. The extensive formula may justify some premium, but vitamin B3 alone contributes little to its high serving cost.

View ingredientView products
Thiamin (Thiamine Hydrochloride, Vitamin B1) · 15 mg OverallScore65
B- Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyD- Value

Thiamine hydrochloride is a standard water-soluble form with reliable basic availability. The 15 mg dose is moderately potent and clearly disclosed. Cost per active dose is high for thiamin within a broad multinutrient powder.

View ingredientView products
Loading alternative details
81 Performance

Target-Mins Calcium Magnesium Potassium 500 mg : 500 mg : 99 mg

Country Life
<p>Stronger ingredient and goal alignment makes this a more capable alternative, with 500mg of Calcium as Calcium Alpha-Ketoglutarate. Its coverage of Calcium and Potassium supports the intended comparison, though the input does not provide independent testing or absorption evidence.</p>
69 Performance

Extra Strength Hair Skin & Nails

21st Century
<p>Stronger ingredient and goal alignment makes this a more capable alternative, with 1500mcg of Vitamin A as Retinyl Palmitate. Its coverage of Niacin and Choline supports the intended comparison, though the input does not provide independent testing or absorption evidence.</p>
68 Performance

Hair Skin & Nails

Sundown
<p>Stronger ingredient and goal alignment makes this a more capable alternative, with 1500mcg of Vitamin A as Vitamin A Palmitate. Its coverage of Niacin and Choline supports the intended comparison, though the input does not provide independent testing or absorption evidence.</p>
81 Budget

Target-Mins Calcium Magnesium Potassium 500 mg : 500 mg : 99 mg

Country Life
<p>Lower serving cost makes this a more economical option while the label provides 500mg of Calcium as Calcium Alpha-Ketoglutarate. Its overlap with Calcium and Potassium keeps the comparison relevant, though the provided data does not include independent testing.</p>
69 Budget

Extra Strength Hair Skin & Nails

21st Century
<p>Lower serving cost makes this a more economical option while the label provides 1500mcg of Vitamin A as Retinyl Palmitate. Its overlap with Niacin and Choline keeps the comparison relevant, though the provided data does not include independent testing.</p>
68 Budget

Hair Skin & Nails

Sundown
<p>Lower serving cost makes this a more economical option while the label provides 1500mcg of Vitamin A as Vitamin A Palmitate. Its overlap with Niacin and Choline keeps the comparison relevant, though the provided data does not include independent testing.</p>
81 Value

Target-Mins Calcium Magnesium Potassium 500 mg : 500 mg : 99 mg

Country Life
<p>Better value comes from a lower serving cost alongside 500mg of Calcium as Calcium Alpha-Ketoglutarate. The formula remains aligned with Calcium and Potassium, though the provided data does not establish absorption or independent testing.</p>
69 Value

Extra Strength Hair Skin & Nails

21st Century
<p>Better value comes from a lower serving cost alongside 1500mcg of Vitamin A as Retinyl Palmitate. The formula remains aligned with Niacin and Choline, though the provided data does not establish absorption or independent testing.</p>
68 Value

Hair Skin & Nails

Sundown
<p>Better value comes from a lower serving cost alongside 1500mcg of Vitamin A as Vitamin A Palmitate. The formula remains aligned with Niacin and Choline, though the provided data does not establish absorption or independent testing.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
    Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
    Randomized trial80 participantsAnti-Inflammatory Support forBromelain
  2. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
    Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
    Meta-analysis6 studies pooledAnti-Inflammatory Support forBromelain
  3. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
    Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
    Randomized trial12 participantsAnti-Inflammatory Support forBromelain
  4. An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
    Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
    Randomized trial42 participantsAnti-Inflammatory Support forBromelain
  5. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
    Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
    Narrative reviewAnti-Inflammatory Support forBromelain
  6. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  7. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  8. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  9. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  10. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  11. Glycine treatment decreases proinflammatory cytokines and increases interferon-gamma in patients with type 2 diabetes.
    Cruz M; Maldonado-Bernal C; Mondragón-Gonzalez R; Sanchez-Barrera R; Wacher NH; Carvajal-Sandoval G; Kumate J · Journal of endocrinological investigation · 2009
    Randomized trial74 participantsAnti-Inflammatory Support forGlycine
  12. Effect of oral glycine on the clinical, spirometric and inflammatory status in subjects with cystic fibrosis: a pilot randomized trial.
    Vargas MH; Del-Razo-Rodríguez R; López-García A; Lezana-Fernández JL; Chávez J; Furuya MEY; Marín-Santana JC · BMC pulmonary medicine · 2018
    Randomized trial13 participantsAnti-Inflammatory Support forGlycine
  13. Subgingival air polishing (glycine powder) versus minocycline hydrochloride: efficacy in residual periodontal pockets following endoscope-assisted scaling and root planing.
    Guo X; Bai H; Lu X; Guo J; Qi Y; Huo X; Li S · Clinical oral investigations · 2026
    Randomized trial80 participantsAnti-Inflammatory Support forGlycine
  14. Long-term Implant Maintenance: A Systematic Review of Home and Professional Care Strategies in Supportive Implant Therapy.
    Araújo TG; Moreira CS; Neme RA; Luan H; Bertolini M · Brazilian dental journal · 2024
    Systematic review13 studies pooledAnti-Inflammatory Support forGlycine
  15. Analysis of the factors influencing the occurrence of peri-implantitis in patients with implant-supported restoration and study on the maintenance effect of subgingival sandblasting.
    Pan T; Meng W; Zhang M; Xie Y; Chen Z; Zhou M; Yin L; Xie H · BMC oral health · 2026
    Randomized trial198 participantsAnti-Inflammatory Support forGlycine
  16. The effects of rutin flavonoid supplement on glycemic status, lipid profile, atherogenic index of plasma, brain-derived neurotrophic factor (BDNF), some serum inflammatory, and oxidative stress factors in patients with type 2 diabetes mellitus: A double-blind, placebo-controlled trial.
    Bazyar H; Moradi L; Zaman F; Zare Javid A · Phytotherapy research : PTR · 2023
    Randomized trial50 participantsAnti-Inflammatory Support forRutin
  17. Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature.
    Muvhulawa N; Dludla PV; Ziqubu K; Mthembu SXH; Mthiyane F; Nkambule BB; Mazibuko-Mbeje SE · Pharmacological research · 2022
    Systematic reviewAnti-Inflammatory Support forRutin
  18. Rutin-loaded chitosan microspheres: Characterization and evaluation of the anti-inflammatory activity.
    Cosco D; Failla P; Costa N; Pullano S; Fiorillo A; Mollace V; Fresta M; Paolino D · Carbohydrate polymers · 2018
    OtherAnti-Inflammatory Support forRutin
  19. Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-controlled trial.
    Henrotin Y; Pap T; Lieten S; Badot V; Dubuc JE; Urbin-Choffray D; von Eynatten M; Johansen OE; Rau S; Brabants K · RMD open · 2025
    Randomized trial45 participantsAnti-Inflammatory Support forRutin
  20. The Impact of the Combination of Proteolytic Enzyme and Rutin on the Post-operative Management of Inflammation: A Randomized, Controlled, Double-Blind, Comparative Clinical Trial
    Rathi PC, Rathi CL, Risbud SP, Ganu GP · Cureus · 2024
    Randomized trial65 participantsAnti-Inflammatory Support forRutin
  21. Oxidative stress and inflammation in obesity after taurine supplementation: a double-blind, placebo-controlled study.
    Rosa FT; Freitas EC; Deminice R; Jordão AA; Marchini JS · European journal of nutrition · 2015
    Randomized trial24 participantsAnti-Inflammatory Support forTaurine
  22. Effect of taurine supplementation on preventing ventilator-associated pneumonia in pediatrics under mechanical ventilation, a randomized controlled double-blind clinical trial.
    Shirzad-Yazdi N; Shorafa E; Abootalebi SN; Heidari R; Hojabri K; Doostfatemeh M; Masjedi F; Vazin A; Shafiekhani M · Frontiers in pediatrics · 2025
    Randomized trial77 participantsAnti-Inflammatory Support forTaurine
  23. Effect of taurine in muscle damage markers and inflammatory cytokines in running exercise.
    Wang Y; Xu T; Zhao H; Gu C; Li Z · Frontiers in physiology · 2022
    Non-randomized trial10 participantsAnti-Inflammatory Support forTaurine
  24. Exercise and taurine in inflammation, cognition, and peripheral markers of blood-brain barrier integrity in older women.
    Chupel MU; Minuzzi LG; Furtado G; Santos ML; Hogervorst E; Filaire E; Teixeira AM · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2018
    Randomized trial48 participantsAnti-Inflammatory Support forTaurine
  25. Taurine supplementation has anti-atherogenic and anti-inflammatory effects before and after incremental exercise in heart failure.
    Ahmadian M; Roshan VD; Aslani E; Stannard SR · Therapeutic advances in cardiovascular disease · 2017
    Randomized trialAnti-Inflammatory Support forTaurine
  26. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  27. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  28. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  29. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  30. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  31. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  32. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  33. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  34. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  35. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  36. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  37. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  38. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  39. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  40. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  41. Implantoplasty Versus Glycine Air Abrasion for the Surgical Treatment of Peri-implantitis: A Randomized Clinical Trial.
    Lasserre JF; Brecx MC; Toma S · The International journal of oral & maxillofacial implants · 2020
    Randomized trial31 participantsBone Health forGlycine
  42. Amino Acid Intakes Are Associated With Bone Mineral Density and Prevalence of Low Bone Mass in Women: Evidence From Discordant Monozygotic Twins.
    Jennings A; MacGregor A; Spector T; Cassidy A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
    Cross-sectional study135 participantsBone Health forGlycine
  43. Type V osteogenesis imperfecta: a new form of brittle bone disease.
    Glorieux FH; Rauch F; Plotkin H; Ward L; Travers R; Roughley P; Lalic L; Glorieux DF; Fassier F; Bishop NJ · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2001
    Other3 participantsBone Health forGlycine
  44. Associations of Dietary and Circulating Choline and Glycine With Bone Mineral Density: UK Biobank Analyses With Mendelian Randomization.
    Chen S; Lu R; Zhang Y; Li Y; Cao X; Yang H; Lin J · International journal of endocrinology · 2026
    Cross-sectional study18,769 participantsBone Health forGlycine
  45. Metabolomic insights into amino acid signatures and pathways associated with osteoporosis in Iranian elderly population.
    Dehghanbanadaki H; Soltani A; Majidi Z; Rezaei-Tavirani M; Shafiee G; Ostovar A; Bandarian F; Najjar N; Larijani B; Nabipour I; Khashayar P; Fahimfar N; Razi F · Frontiers in medicine · 2025
    Cross-sectional study1,916 participantsBone Health forGlycine
  46. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  47. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  48. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  49. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  50. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  51. Dairy product consumption, eating habits, sedentary behaviour and physical activity association with bone mineral density among adolescent boys: a cross-sectional observational study.
    Kopiczko A; Czapla M; Juárez-Vela R; Ross C; Uchmanowicz B · BMC pediatrics · 2024
    Cross-sectional study115 participantsBone Health forPhosphorus
  52. Burosumab Improved Histomorphometric Measures of Osteomalacia in Adults with X-Linked Hypophosphatemia: A Phase 3, Single-Arm, International Trial.
    Insogna KL; Rauch F; Kamenický P; Ito N; Kubota T; Nakamura A; Zhang L; Mealiffe M; San Martin J; Portale AA · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020
    Single-arm trial14 participantsBone Health forPhosphorus
  53. Early high calcium and phosphorus intake by parenteral nutrition prevents short-term bone strength decline in preterm infants.
    Pereira-da-Silva L; Costa A; Pereira L; Filipe A; Virella D; Leal E; Moreira A; Rosa M; Mendes L; Serelha M · Journal of pediatric gastroenterology and nutrition · 2011
    Randomized trialBone Health forPhosphorus
  54. Phosphate Metabolism in Health and Disease.
    Peacock M · Calcified tissue international · 2021
    Narrative reviewBone Health forPhosphorus
  55. Expert consensus on clinical management of metabolic bone disease of prematurity (2021).
    Yan-Mei C; Xin-Zhu L; Rong Z; Xi-Hong L; Xiao-Mei T; Ping-Yang C; Zhi-Chun F; Nutritional Committee of Neonatology Branch of Chinese Medical Doctor Association; Neonatal Nutrition and Health Management Group, Professional Committee of Child Health, Chinese Medical Doctor Association; Editorial Committee of Chinese Journal of Contemporary Pediatrics. · Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021
    Guideline / consensusBone Health forPhosphorus
  56. The effect of choline-stabilized orthosilicic acid in patients with peri-implantitis: an exploratory randomized, double-blind, placebo controlled study.
    Teughels W; Celik GU; Tarce M; De Cock I; Persyn SM; Haytac MC · BMC oral health · 2021
    Randomized trial21 participantsBone Health forSilicon
  57. Calcium Phosphate Modified with Silicon vs. Bovine Hydroxyapatite for Alveolar Ridge Preservation: Densitometric Evaluation, Morphological Changes and Histomorphometric Study.
    Cadenas-Vacas G; Martínez-Rodríguez N; Barona-Dorado C; Sánchez-Labrador L; Cortés-Bretón Brinkmann J; Meniz-García C; Martínez-González JM · Materials (Basel, Switzerland) · 2021
    Non-randomized trialBone Health forSilicon
  58. Silicon: a review of its potential role in the prevention and treatment of postmenopausal osteoporosis.
    Price CT; Koval KJ; Langford JR · International journal of endocrinology · 2013
    Narrative reviewBone Health forSilicon
  59. Osteogenic Effect of a Bioactive Calcium Alkali Phosphate Bone Substitute in Humans.
    Knabe C; Adel-Khattab D; Rezk M; Cheng J; Berger G; Gildenhaar R; Wilbig J; Günster J; Rack A; Heiland M; Knauf T; Stiller M · Bioengineering (Basel, Switzerland) · 2023
    Clinical trial38 participantsBone Health forSilicon
  60. Silicon and bone health.
    Jugdaohsingh R · The journal of nutrition, health & aging · 2007
    Narrative reviewBone Health forSilicon
  61. Can Dietary Intake of Vitamin C-Oriented Foods Reduce the Risk of Osteoporosis, Fracture, and BMD Loss? Systematic Review With Meta-Analyses of Recent Studies.
    Zeng LF; Luo MH; Liang GH; Yang WY; Xiao X; Wei X; Yu J; Guo D; Chen HY; Pan JK; Huang HT; Liu Q; Guan ZT; Han YH; Zhao D; Zhao JL; Hou SR; Wu M; Lin JT; Li JH; Liang WX; Ou AH; Wang Q; Li ZP; Liu J · Frontiers in endocrinology · 2020
    Meta-analysis19,484 participants17 studies pooledBone Health forVitamin C
  62. Dietary vitamin C intake and the risk of hip fracture: a dose-response meta-analysis.
    Sun Y; Liu C; Bo Y; You J; Zhu Y; Duan D; Cui H; Lu Q · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Meta-analysis6 studies pooledBone Health forVitamin C
  63. Smoking, antioxidant vitamins, and the risk of hip fracture.
    Melhus H; Michaëlsson K; Holmberg L; Wolk A; Ljunghall S · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1999
    Cohort study66,651 participantsBone Health forVitamin C
  64. Micronutrients and the risk of hip fracture: Case-control study.
    Torbergsen AC; Watne LO; Wyller TB; Frihagen F; Strømsøe K; Bøhmer T; Mowe M · Clinical nutrition (Edinburgh, Scotland) · 2018
    Case-control study189 participantsBone Health forVitamin C
  65. Favorable effect of dietary vitamin C on bone mineral density in postmenopausal women (KNHANES IV, 2009): discrepancies regarding skeletal sites, age, and vitamin D status.
    Kim YA; Kim KM; Lim S; Choi SH; Moon JH; Kim JH; Kim SW; Jang HC; Shin CS · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Cross-sectional study1,196 participantsBone Health forVitamin C
  66. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  67. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  68. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  69. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  70. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  71. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health Nail Health forBiotin Skin Health forSilicon
  72. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health forBiotin
  73. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  74. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  75. Menkes disease and response to copper histidine: An Indian case series.
    Yoganathan S; Sudhakar SV; Arunachal G; Thomas M; Subramanian A; George R; Danda S · Annals of Indian Academy of Neurology · 2022
    Case series4 participantsHair Health forCopper
  76. Trace element levels in alopecia areata.
    Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
    Case-control study100 participantsHair Health forCopper
  77. UV damage to hair and the effect of antioxidants and metal chelators.
    Millington KR; Marsh JM · International journal of cosmetic science · 2021
    In vitro / ex vivo studyHair Health forCopper
  78. Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
    Marsh JM; Davis MG; Lucas RL; Reilman R; Styczynski PB; Li C; Mamak M; McComb DW; Williams RE; Godfrey S; Navqi KR; Chechik V · International journal of cosmetic science · 2016
    In vitro / ex vivo studyHair Health forCopper
  79. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  80. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
    Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
    Observational study1,407 participantsHair Health forSelenium
  81. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
    Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
    Randomized trial64 participantsHair Health forSelenium
  82. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
    Meta-analysis764 participantsHair Health forSelenium
  83. Scientific opinion on the tolerable upper intake level for selenium.
    EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
    Systematic reviewHair Health forSelenium
  84. Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin.
    Barel A; Calomme M; Timchenko A; De Paepe K; Demeester N; Rogiers V; Clarys P; Vanden Berghe D · Archives of dermatological research · 2006
    Randomized trial50 participantsHair Health Nail Health forSilicon
  85. Effect of oral intake of choline-stabilized orthosilicic acid on hair tensile strength and morphology in women with fine hair
    R R Wickett, E Kossmann, A Barel, N Demeester, P Clarys, D Vanden Berghe, M Calomme · Archives of Dermatological Research · 2007
    Randomized trial48 participantsHair Health forSilicon
  86. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  87. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  88. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  89. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  90. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  91. Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis.
    Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Meta-analysis2,039 participants14 studies pooledHair Health forVitamin D
  92. Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
    Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
    Randomized trial60 participantsHair Health forVitamin D
  93. Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
    Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
    Meta-analysisHair Health forVitamin D
  94. Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
    El Taieb MA; Hegazy EM; Ibrahim HM; Osman AB; Abualhamd M · Archives of dermatological research · 2020
    Randomized trial60 participantsHair Health forVitamin D
  95. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
    Chen Y; Dong X; Wang Y; Li Y; Xiong L; Li L · Journal of cosmetic dermatology · 2024
    Meta-analysis10,670 participants23 studies pooledHair Health forVitamin D
  96. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  97. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  98. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  99. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  100. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  101. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  102. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  103. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  104. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  105. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  106. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  107. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  108. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  109. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  110. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  111. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  112. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  113. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  114. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  115. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  116. Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects.
    Meydani SN; Barklund MP; Liu S; Meydani M; Miller RA; Cannon JG; Morrow FD; Rocklin R; Blumberg JB · The American journal of clinical nutrition · 1990
    Randomized trial32 participantsImmunity forVitamin E
  117. Immunomodulatory effects of palm-derived tocotrienol-rich fraction in healthy volunteers following influenza vaccination: A randomised clinical trial.
    Chen S; Ahmad B; Palanisamy UD; Hafid SRA; Selvaduray KR; Radhakrishnan AK · Nutrition research (New York, N.Y.) · 2026
    Randomized trial150 participantsImmunity forVitamin E
  118. Effects of supplementation with tocotrienol-rich fraction on immune response to tetanus toxoid immunization in normal healthy volunteers.
    Mahalingam D; Radhakrishnan AK; Amom Z; Ibrahim N; Nesaretnam K · European journal of clinical nutrition · 2011
    Randomized trialImmunity forVitamin E
  119. Vitamin E and beta-carotene supplementation and hospital-treated pneumonia incidence in male smokers.
    Hemilä H; Virtamo J; Albanes D; Kaprio J · Chest · 2004
    Randomized trial29,133 participantsImmunity forVitamin E
  120. Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial.
    Meydani SN; Meydani M; Blumberg JB; Leka LS; Siber G; Loszewski R; Thompson C; Pedrosa MC; Diamond RD; Stollar BD · JAMA · 1997
    Randomized trial88 participantsImmunity forVitamin E
  121. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  122. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  123. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  124. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  125. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  126. Biotin for the treatment of nail disease: what is the evidence?
    Lipner SR; Scher RK · The Journal of dermatological treatment · 2018
    Narrative reviewNail Health forBiotin
  127. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy.
    Colombo VE; Gerber F; Bronhofer M; Floersheim GL · Journal of the American Academy of Dermatology · 1991
    Other32 participantsNail Health forBiotin
  128. Treatment of brittle nail with a hydroxypropyl chitosan-based lacquer, alone or in combination with oral biotin: A randomized, assessor-blinded trial.
    Chiavetta A; Mazzurco S; Secolo MP; Tomarchio G; Milani M · Dermatologic therapy · 2020
    Randomized trial50 participantsNail Health forBiotin
  129. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forBiotin Nail Health forZinc
  130. Nail Supplements: When, How, and Why?
    Zaraa I; Richert B · Skin appendage disorders · 2026
    Narrative reviewNail Health forSilicon
  131. Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
    Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
    Other20 participantsNail Health forVitamin C
  132. Assessment of the skin efficacy and acceptability of a cosmetic product in the treatment of the forearm hypertrichosis in female patients.
    Berardesca E; Cameli N; Piacentini M; Veraldi S; Celleno L · Journal of cosmetic dermatology · 2021
    Non-randomized trial69 participantsSkin Health forGlycine
  133. Antiirritant properties of polyols and amino acids.
    Korponyai C; Kovács RK; Erös G; Dikstein S; Kemény L · Dermatitis : contact, atopic, occupational, drug · 2011
    Clinical trialSkin Health forGlycine
  134. The Efficacy of a Silicone Sheet in Postoperative Scar Management.
    Kim JS; Hong JP; Choi JW; Seo DK; Lee ES; Lee HS · Advances in skin & wound care · 2018
    Randomized trialSkin Health forSilicon
  135. A non-inferiority study to compare the effect of silica gel fiber dressing with alginate dressing on healing of venous leg ulcers.
    Zhang L; Yang J; Wang H; Cai Y; Zhao W; Dong R; Liu D; Lu X · Wound management & prevention · 2023
    Randomized trial130 participantsSkin Health forSilicon
  136. Retrospective Study on the Clinical Superiority of the Vacuum-Assisted Closure System with a Silicon-based Dressing over the Conventional Tie-over Bolster Technique in Skin Graft Fixation.
    Chou PR; Wu SH; Hsieh MC; Huang SH · Medicina (Kaunas, Lithuania) · 2020
    Cohort study26 participantsSkin Health forSilicon
  137. Silicon gel sheeting for preventing and treating hypertrophic and keloid scars.
    O'Brien L; Pandit A · The Cochrane database of systematic reviews · 2006
    Meta-analysis559 participants13 studies pooledSkin Health forSilicon
  138. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  139. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  140. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  141. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  142. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  143. Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis.
    Javanbakht MH; Keshavarz SA; Djalali M; Siassi F; Eshraghian MR; Firooz A; Seirafi H; Ehsani AH; Chamari M; Mirshafiey A · The Journal of dermatological treatment · 2011
    Randomized trial45 participantsSkin Health forVitamin E
  144. Serum vitamin E levels and chronic inflammatory skin diseases: A systematic review and meta-analysis.
    Liu X; Yang G; Luo M; Lan Q; Shi X; Deng H; Wang N; Xu X; Zhang C · PloS one · 2022
    Meta-analysis20 studies pooledSkin Health forVitamin E
  145. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forVitamin E Skin Health forZinc
  146. Effects of tocotrienol on aging skin: A systematic review.
    Ghazali NI; Mohd Rais RZ; Makpol S; Chin KY; Yap WN; Goon JA · Frontiers in pharmacology · 2022
    Systematic reviewSkin Health forVitamin E
  147. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
    Stahl W; Heinrich U; Jungmann H; Sies H; Tronnier H · The American journal of clinical nutrition · 2000
    Randomized trialSkin Health forVitamin E
  148. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  149. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  150. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  151. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  152. What did we learn in 35 years of research on nutrition and supplements for age-related macular degeneration: a systematic review.
    Pameijer EM; Heus P; Damen JAA; Spijker R; Hooft L; Ringens PJ; Imhof SM; van Leeuwen R · Acta ophthalmologica · 2023
    Systematic review27 studies pooledVision Support forCopper
  153. Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2.
    Agrón E; Mares J; Clemons TE; Swaroop A; Chew EY; Keenan TDL; AREDS and AREDS2 Research Groups · Ophthalmology · 2021
    Cohort study8,242 participantsVision Support forCopper
  154. Association between late age-related macular degeneration and dietary intake of copper, iron, zinc and selenium: a 2005-2008 NHANES cross-sectional observational study.
    Lu Y; Li C; Liu Y; Wu T; Lu P · BMC ophthalmology · 2025
    Observational study4,996 participantsVision Support forCopper
  155. Associations between dietary nutrient intake and the risk of multiple age-related ocular diseases: evidence from longitudinal analysis.
    Yang Y; Zou H · The journal of nutrition, health & aging · 2026
    Cohort study103,192 participantsVision Support forCopper
  156. Dietary habits and dietary nutrient intake in patients with age-related macular degeneration: A case-control study.
    Šalková Kráľová J; Kolář P; Kapounová Z; Veselý P; Derflerová Brázdová Z · Central European journal of public health · 2023
    Case-control study151 participantsVision Support forCopper
  157. Effect of Ginkgo biloba extracts in the prevention of posterior capsule opacification after cataract surgery: A randomized clinical trial.
    Amiri AA; Jafari R; Amiri AA; Rad HA; Daneshvar F; Charati JY; Amiri AA · Oman journal of ophthalmology · 2025
    Randomized trial144 participantsVision Support forGinkgo
  158. Effect of Ginkgo biloba extract on preexisting visual field damage in normal tension glaucoma.
    Quaranta L; Bettelli S; Uva MG; Semeraro F; Turano R; Gandolfo E · Ophthalmology · 2003
    Randomized trial27 participantsVision Support forGinkgo
  159. [Ginkgo extract in impaired vision--treatment with special extract EGb 761 of impaired vision due to dry senile macular degeneration].
    Fies P; Dienel A · Wiener medizinische Wochenschrift (1946) · 2002
    Randomized trial99 participantsVision Support forGinkgo
  160. Short-term effects of Ginkgo biloba extract on peripapillary retinal blood flow in normal tension glaucoma.
    Park JW; Kwon HJ; Chung WS; Kim CY; Seong GJ · Korean journal of ophthalmology : KJO · 2012
    Randomized trial30 participantsVision Support forGinkgo
  161. [The course of color vision in early diabetic retinopathy treated with Ginkgo biloba extract. A preliminary double-blind versus placebo study].
    Lanthony P; Cosson JP · Journal francais d'ophtalmologie · 1989
    Randomized trial29 participantsVision Support forGinkgo
  162. Effects of taurine supplementation on VDT work induced visual stress.
    Zhang M; Bi LF; Ai YD; Yang LP; Wang HB; Liu ZY; Sekine M; Kagamimori S · Amino acids · 2005
    Randomized trial25 participantsVision Support forTaurine
  163. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  164. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  165. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  166. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  167. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc