Extra Strength Hair Skin & Nails
21st Century
Extra Strength Hair Skin & Nails
4.6
★ ★ ★ ★ ★
(16870 ratings)
Biotin 5000 mcg
Vitamin B5 15 mg
Choline 10 mg
Thiamin 5 mg
Horsetail 3 mg
Niacin 25 mg
Phosphorus 180 mg
Score 75.0
A biotin-focused supplement with a good range of B vitamins and essential minerals, effective for primary hair, skin, and nail goals, but with insufficient doses of collagen and horsetail for significant impact beyond general nutritional support.
Quantity: 90 Tablet(s)Servings size: 3 Tablet(s) (30 servings)
Selected goals:
Other goals:
Bone Health
Heart Health
Joint Health
Muscle Gain
Energy
leaderboard Score 75.0
A biotin-focused supplement with a good range of B vitamins and essential minerals, effective for primary hair, skin, and nail goals, but with insufficient doses of collagen and horsetail for significant impact beyond general nutritional support.
insights Analysis
21st Century's Extra Strength Hair Skin & Nails is primarily a multivitamin formulation heavily emphasizing biotin, a crucial nutrient for the health of hair, skin, and nails. Its 5000mcg biotin content aligns with doses commonly recommended and found effective in online reviews for promoting hair growth and nail strength, especially in individuals with deficiencies. The product also includes a robust spectrum of B vitamins, vital for energy metabolism and overall cellular function, alongside essential minerals like Calcium, Phosphorus, Zinc, and Manganese, which contribute to bone, skin, and general health. While the formula is well-rounded for general nutritional support, the inclusion of ingredients like collagen (50mg) and horsetail (3mg) at such low quantities is largely symbolic rather than therapeutically effective for promoting 'extra strength' benefits in those areas, as evidence-based dosages for these ingredients are typically in gram amounts for collagen and hundreds of milligrams for horsetail extract.
- Contains a high and effective dose of Biotin (5000mcg) for noticeable benefits in hair and nail growth.
- Includes a comprehensive blend of B vitamins that support energy metabolism and overall cellular health.
- Provides essential minerals like Zinc, Calcium, and Phosphorus which contribute to skin, nail, and bone health.
- Widely available and has a large number of positive customer reviews, indicating general user satisfaction with its core benefits.
- The collagen content (50mg) is significantly underdosed, rendering it largely ineffective for its stated goals of skin elasticity or joint health.
- The horsetail powder content (3mg) is extremely low and unlikely to provide meaningful silica for hair and nail strengthening.
- Some listed goals like 'Testosterone Support' are not directly addressed or supported by the product's ingredients.
- High doses of biotin, while beneficial for some, can interfere with certain laboratory blood tests, potentially leading to inaccurate results.
- Individuals taking this supplement should inform their healthcare providers, especially if undergoing laboratory tests, as high biotin levels can interfere with certain assays, including thyroid function tests.
$9.88($0.32 per serving)
 Amazon | $ 9.88 | |
 iHerb | $ 9.99 |
bolt Effectiveness for goals
Biotin, a B vitamin, is essential for the metabolism of fats, carbohydrates, and proteins, including keratin. Keratin is a primary protein that forms hair and nails, and Biotin supports its formation, which may help strengthen these tissues. Many supplements contain Biotin to promote healthier hair and stronger nails.
Collagen is a fundamental structural protein found in the skin, providing its firmness, elasticity, and hydration. As natural collagen production declines with age, supplementing with hydrolyzed collagen may help support skin's integrity. It aims to reduce the appearance of fine lines and improve overall skin texture.
Vitamins A, C, and E are potent antioxidants that help protect skin cells from damage caused by free radicals. Vitamin C is crucial for collagen synthesis and brightens skin, while Vitamin A supports healthy cell turnover. Vitamin E contributes to skin moisture and can aid in overall skin repair.
Zinc is an essential mineral vital for cell growth, immune function, and protein synthesis, all of which are critical for healthy skin and hair. It plays a role in wound healing and can help regulate the oil glands around hair follicles. Adequate zinc intake may support hair strength and clear skin.
Horsetail powder is recognized as a natural source of silica, a compound believed to be beneficial for connective tissues. Silica may support the structural integrity of hair strands and nails, potentially contributing to their strength, elasticity, and overall healthy appearance. Its role is often linked to enhancing collagen formation.
schedule Dosage, timing & forms
Yes, very high doses of biotin, such as those found in some supplements, can interfere with certain lab tests, particularly those that use biotin-streptavidin technology. It's advisable to inform your doctor about all supplements you are taking before any lab work. Your doctor may recommend discontinuing biotin a few days prior to testing.
Yes, fat-soluble vitamins like A, D, and E are best absorbed when taken with a meal that contains some dietary fat. This helps facilitate their absorption into the body by stimulating bile production. Taking them without food may reduce their bioavailability.
High doses of certain minerals can potentially compete for absorption pathways. For example, very high levels of calcium might interfere with zinc absorption. However, the amounts typically found in balanced multi-nutrient supplements are generally formulated to minimize significant competition for most individuals.
Calcium carbonate typically requires stomach acid for optimal absorption and is best taken with food. Dicalcium phosphate is a common source of both calcium and phosphorus, and its absorption characteristics are generally good, often less dependent on stomach acid than calcium carbonate. Both forms contribute to overall calcium intake.
While there's no strict rule, many people prefer to take B vitamins in the morning or early afternoon because they play a role in energy metabolism. Taking them later in the day might, for some individuals, interfere with sleep due to their energizing effects. Consistency is often more important than the exact timing.
health_and_safety Safety & interactions
High doses of biotin, an ingredient often found in these supplements, can potentially affect the results of various lab tests, including those for thyroid function and cardiac markers. It is advisable to inform your healthcare provider about all supplements you are taking before any lab work. This helps ensure accurate diagnostic results.
Ingredients like Vitamin A, Vitamin E, and certain bioflavonoids (such as rutin) can potentially interact with anticoagulant medications. Individuals on blood thinners should consult their healthcare provider before using supplements containing these ingredients to assess potential risks.
The safety of specific nutrient combinations during pregnancy and breastfeeding has not been fully established for all ingredients. It is crucial to consult a healthcare professional before taking any new supplement during these periods to assess potential risks and benefits for both mother and child.
Minerals such as calcium, magnesium, and zinc can interfere with the absorption and effectiveness of various medications, including some antibiotics and thyroid hormones. Taking these supplements separately from medications, as advised by a healthcare provider, may help minimize interactions.
This supplement provides Vitamin A as Retinyl Palmitate. Excessive intake of Vitamin A from multiple sources, including other supplements or a diet high in liver, can lead to accumulation and potential adverse effects. It is advisable to monitor total daily Vitamin A intake from all sources.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin A | 1500 mcg |
Vitamin C | 60 mg |
Vitamin D3 | 25 mcg |
Vitamin E | 6.75 mg |
Thiamine | 5 mg |
Riboflavin | 2 mg |
Niacin | 25 mg |
Vitamin B6 | 5 mg |
Folate | 334 mcg DFE |
Vitamin B12 | 8 mcg |
Biotin | 5000 mcg |
Pantothenic Acid | 15 mg |
Choline | 10 mg |
Calcium | 372 mg |
Phosphorus | 180 mg |
Magnesium | 50 mg |
Zinc | 7.5 mg |
Manganese | 2 mg |
PABA | 10 mg |
Inositol | 30 mg |
Citrus Bioflavonoid / Rutin Complex | 38 mg |
Horsetail powder | 3 mg |
Collagen | 50 mg |
Categories
Biotin 90.0
The 5000mcg dose of D-Biotin is a standout feature, providing a robust amount that is highly effective for addressing deficiencies and promoting significant improvements in hair, skin, and nail strength and growth, as widely supported by consumer reviews and some research.
Niacin 75.0
The Niacinamide form is included at 25mg, which is a good dose for general metabolic support without causing the 'niacin flush' associated with nicotinic acid. It contributes effectively to energy and cardiovascular health indirectly.
Thiamin 70.0
Thiamin (Vitamin B1) is included at 5mg as Thiamine Hydrochloride, a standard and effective dose for its role in carbohydrate metabolism and nervous system function, contributing to the product's energy goals.
Goals
Hair Health 85.0
The substantial 5000mcg dose of Biotin is the primary driver for hair health benefits, a quantity widely recognized and clinically studied for its role in strengthening hair and reducing breakage, particularly in cases of deficiency. The inclusion of B vitamins and zinc further supports overall scalp and hair follicle health.
Nail Health 80.0
Biotin is highly effective for strengthening brittle nails and promoting growth, with 5000mcg being a robust dose for this purpose. The presence of Calcium, Phosphorus, and Manganese also provides foundational support for nail integrity.
Energy 75.0
The comprehensive array of B vitamins (Thiamine, Riboflavin, Niacin, Pantothenic Acid, B6, B12, Folate) are crucial cofactors in energy metabolism, helping the body convert food into energy efficiently. This makes the product a good contributor to general energy levels.
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