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Omega-3 2100 with Vitamin D Vanilla Flavor

Oceanblue Professional
4.7
★ ★ ★ ★ ★
(118 ratings)
Omega-3 2100 mg
Product Image
Score74
Concentrated omega-3 plus vitamin D offers strong nutritional depth. Missing EPA and DHA detail and the ethyl ester form require consideration.
How scoring works
Quantity:120 Softgel(s) • (60 servings)
Goals:
Joint Health
Skin Health
Metabolism Boost

Score 74

Concentrated omega-3 plus vitamin D offers strong nutritional depth. Missing EPA and DHA detail and the ethyl ester form require consideration.
How scoring works
$45.04($0.75 per serving)
iHerb
$ 45.04
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Analysis

The formula provides 2,100 mg total omega-3 ethyl esters plus 50 mcg vitamin D3. Mixed tocopherols add some oxidation protection to the concentrated fatty-acid serving.

The amount is meaningful for skin and joint inflammatory pathways, while vitamin D adds bone and muscle relevance. EPA and DHA are not separated, so the specific active profile cannot be confirmed.

Sixty servings provide useful depth at a moderate cost. Ethyl esters absorb less efficiently than triglyceride forms without a fat-containing meal, and source and purity evidence are missing.

Who is it for
  • Adults seeking high-total omega-3
  • People wanting omega-3 with vitamin D
  • Users willing to take softgels with food
Best for
  • High-dose omega-3 supplementation
  • Secondary joint support
  • Omega-3 plus vitamin D routines

Pros

  • Provides 2,100 mg total omega-3
  • Includes 50 mcg vitamin D3
  • Uses mixed tocopherols
  • Concentrated serving

Cons

  • EPA and DHA are not separated
  • Ethyl ester form is less favorable without food
  • Oil source is unknown
  • Purity testing is absent

Warnings

  • Take ethyl ester omega-3 with a fat-containing meal
  • High-dose omega-3 may increase bleeding tendency with anticoagulant medicines
  • Count vitamin D from all supplements to avoid excessive intake

Nutrient quality

82 Highest impact

A concentrated omega-3 amount, useful vitamin D, and antioxidant support create strong active depth. The ethyl-ester form and missing EPA, DHA, source, and purity details temper the quality case.

Ingredient transparency

69 High impact

Listed active ingredients carry amounts and no proprietary blend hides a supplied dose. Missing fatty-acid detail, complete directions, or an excipient list keeps disclosure incomplete.

Customer satisfaction

62 Moderate impact

The supplied average rating is strong and the review volume is limited. Specific comments are absent, so repeated complaints and purpose-specific experiences cannot be assessed.

Value for money

83 Highest impact

Concentrated active delivery and relevant supporting nutrients provide strong value. Incomplete fatty-acid and sourcing detail prevents a top-tier comparison.

Report analysis

Goals

Joint Health
Joint Health
Impact
Highest effect
A- Goal FitB Strength of SupportC+ CoverageA- Formula Quality
Omega-3 · 2100 mg

A concentrated 2100 mg omega-3 serving provides strong potential for inflammatory joint support, while vitamin D3 adds a bone-support pathway. The total amount is substantial and the softgel format suits fatty acids.

EPA and DHA are not separately disclosed, and the ethyl-ester form is less readily absorbed than triglyceride forms unless taken with a meal. Missing oil source and purity verification limit confidence in product quality.

Study evidence
Omega-3 Supportive 40 studies
Vitamin D Supportive 111 studies
Skin Health
Skin Health
Impact
High effect
B Goal FitB- Strength of SupportB- CoverageA Formula Quality
Vitamin E · 2 mgOmega-3 · 2100 mg

A concentrated omega-3 serving can support skin-barrier lipids and normal inflammatory balance. Vitamin D3 and mixed tocopherols add complementary nutrient and antioxidant support, but missing EPA and DHA amounts weaken precision.

The ethyl-ester form and total amount are disclosed, while the oil source and independent purity testing are not. People using anticoagulant or antiplatelet therapy should review high-dose omega-3 use with a clinician.

Study evidence
Omega-3 Supportive 35 studies
Metabolism Boost
Metabolism Boost
Impact
High effect
C- Goal FitB+ Strength of SupportC CoverageA Formula Quality
Omega-3 · 2100 mgVitamin D · 50 mcg

Concentrated omega-3s and vitamin D3 may support insulin sensitivity and general metabolic health. The formula does not directly raise metabolic rate or provide thermogenic stimulation.

The omega-3 amount is substantial, but ethyl esters are less efficiently absorbed than triglyceride forms and EPA and DHA are not separated. The streamlined formula provides depth in fatty-acid nutrition while covering only a narrow metabolic pathway.

Study evidence
Omega-3 Supportive 42 studies
Vitamin D Supportive 65 studies

Ingredients

IngredientAmount per serving
Calories
25 Calorie(s)
Total Fat
2 Gram(s)
Vitamin D3 (Cholecalciferol)
 50 mcg
Vitamin E (Mixed Tocopherols)
 2 mg
Total Omega-3 Fatty Acids Ethyl Esters
2100 mg
Adults 18–50
Report overview
Omega-3 · 2100 mg OverallScore55
D- Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyA+ Value

The label identifies ethyl-ester omega-3s and mixed tocopherols but does not name the oil source. EPA and DHA are not separated, while the disclosed omega-3 amount indicates a very concentrated formula. Cost per disclosed active gram is excellent, though independent purity verification is missing.

View ingredientView products
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Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  2. Prenatal Omega-3 Supplementation and Eczema Risk among Offspring at Age 36 Months.
    Berman D; Clinton C; Limb R; Somers EC; Romero V; Mozurkewich E · Insights in allergy, asthma & bronchitis · 2020
    Randomized trial84 participantsSkin Health forOmega-3
  3. Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial.
    Stonehouse W; Benassi-Evans B; Bednarz J; Vincent AD; Hall S; Hill CL · The American journal of clinical nutrition · 2022
    Randomized trial235 participantsJoint Health forOmega-3
  4. Effect of Losartan and Fish Oil on Plasma IL-6 and Mobility in Older Persons. The ENRGISE Pilot Randomized Clinical Trial.
    Pahor M; Anton SD; Beavers DP; Cauley JA; Fielding RA; Kritchevsky SB; Leeuwenburgh C; Lewis KH; Liu CK; Lovato LC; Lu J; Manini TM; McDermott MM; Miller ME; Newman AB; Radziszewska B; Stowe CL; Tracy RP; Walkup MP; Wu SS; Ambrosius WT · The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Randomized trial289 participantsJoint Health forOmega-3
  5. Supplementation of fish oil and olive oil in patients with rheumatoid arthritis.
    Berbert AA; Kondo CR; Almendra CL; Matsuo T; Dichi I · Nutrition (Burbank, Los Angeles County, Calif.) · 2005
    Randomized trial43 participantsJoint Health forOmega-3
  6. Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials.
    Wang W; Xu Y; Zhou J; Zang Y · Clinical rheumatology · 2024
    Meta-analysis1,018 participants18 studies pooledJoint Health forOmega-3
  7. Impact of type and dose of oral polyunsaturated fatty acid supplementation on disease activity in inflammatory rheumatic diseases: a systematic literature review and meta-analysis.
    Sigaux J; Mathieu S; Nguyen Y; Sanchez P; Letarouilly JG; Soubrier M; Czernichow S; Flipo RM; Sellam J; Daïen C · Arthritis research & therapy · 2022
    Meta-analysis1,420 participants30 studies pooledJoint Health forOmega-3
  8. A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain.
    Goldberg RJ; Katz J · Pain · 2007
    Meta-analysis17 studies pooledJoint Health forOmega-3
  9. Knee effusion-synovitis volume measurement and effects of vitamin D supplementation in patients with knee osteoarthritis.
    Wang X; Cicuttini F; Jin X; Wluka AE; Han W; Zhu Z; Blizzard L; Antony B; Winzenberg T; Jones G; Ding C · Osteoarthritis and cartilage · 2018
    Randomized trial413 participantsJoint Health forVitamin D
  10. Vitamin D Deficiency Leads to Poorer Health Outcomes and Greater Length of Stay After Total Knee Arthroplasty and Supplementation Improves Outcomes: A Systematic Review and Meta-Analysis.
    Vivek K; Kamal R; Perera E; Gupte CM · JBJS reviews · 2024
    Meta-analysis146,054 participants10 studies pooledJoint Health forVitamin D
  11. Does vitamin D improve symptomatic and structural outcomes in knee osteoarthritis? A systematic review and meta-analysis.
    Zhao ZX; He Y; Peng LH; Luo X; Liu M; He CS; Chen J · Aging clinical and experimental research · 2021
    Meta-analysis1,599 participants6 studies pooledJoint Health forVitamin D
  12. Baseline 25-hydroxyvitamin D levels predict the effects of vitamin D supplementation on joint symptoms and cartilage loss in patients with knee osteoarthritis.
    Wang T; Zheng S; Jin X; Cen H; Zhu Z; Han W; Wluka A; Cicuttini F; Cao P; Ding C · Rheumatology advances in practice · 2025
    Randomized trial413 participantsJoint Health forVitamin D
  13. The Efficacy and Safety of Disease-Modifying Osteoarthritis Drugs for Knee and Hip Osteoarthritis-a Systematic Review and Network Meta-Analysis.
    Yang W; Sun C; He SQ; Chen JY; Wang Y; Zhuo Q · Journal of general internal medicine · 2021
    Meta-analysis11,890 participants28 studies pooledJoint Health forVitamin D
  14. Effects of omega-3 supplementation on glucose and lipid metabolism in patients with gestational diabetes: A meta-analysis of randomized controlled trials.
    Liu W; Gao M; Yang S; Sun C; Bi Y; Li Y; Wang J; Yuan X · Journal of diabetes and its complications · 2023
    Meta-analysis331 participants6 studies pooledMetabolism Boost forOmega-3
  15. Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism.
    Green CJ; Pramfalk C; Charlton CA; Gunn PJ; Cornfield T; Pavlides M; Karpe F; Hodson L · BMJ open diabetes research & care · 2021
    Randomized trial38 participantsMetabolism Boost forOmega-3
  16. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsMetabolism Boost Skin Health forOmega-3
  17. The Effects of Flaxseed Oil Omega-3 Fatty Acids Supplementation on Metabolic Status of Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Mirmasoumi G; Fazilati M; Foroozanfard F; Vahedpoor Z; Mahmoodi S; Taghizadeh M; Esfeh NK; Mohseni M; Karbassizadeh H; Asemi Z · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2018
    Randomized trial60 participantsMetabolism Boost forOmega-3
  18. A combination of omega-3 and plant sterols regulate glucose and lipid metabolism in individuals with impaired glucose regulation: a randomized and controlled clinical trial.
    Wang JF; Zhang HM; Li YY; Xia S; Wei Y; Yang L; Wang D; Ye JJ; Li HX; Yuan J; Pan RR · Lipids in health and disease · 2019
    Randomized trial200 participantsMetabolism Boost forOmega-3
  19. Effects of vitamin D supplementation on insulin resistance and lipid metabolic profiles in women with gestational diabetes mellitus: A randomized controlled trial.
    Duan Y; Zhang S; Ma X; Li L; Jia K · African journal of reproductive health · 2026
    Randomized trial120 participantsMetabolism Boost forVitamin D
  20. Vitamin D3 improves glucose metabolism and attenuates inflammation in prediabetic human and mice.
    Zhang Y; Ni P; Miao Y; Chen H; Tang L; Song H; Li W; Li X · The Journal of nutritional biochemistry · 2024
    Randomized trialMetabolism Boost forVitamin D
  21. Effects of vitamin D and calcium supplementation on pancreatic β cell function, insulin sensitivity, and glycemia in adults at high risk of diabetes: the Calcium and Vitamin D for Diabetes Mellitus (CaDDM) randomized controlled trial.
    Mitri J; Dawson-Hughes B; Hu FB; Pittas AG · The American journal of clinical nutrition · 2011
    Randomized trial92 participantsMetabolism Boost forVitamin D
  22. The Effects of Vitamin D Supplementation on Glycemic Control, Lipid Profiles and C-Reactive Protein Among Patients with Cardiovascular Disease: a Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Ostadmohammadi V; Milajerdi A; Ghayour-Mobarhan M; Ferns G; Taghizadeh M; Badehnoosh B; Mirzaei H; Asemi Z · Current pharmaceutical design · 2020
    Meta-analysis630 participants8 studies pooledMetabolism Boost forVitamin D
  23. The Effect of Improved Serum 25-Hydroxyvitamin D Status on Glycemic Control in Diabetic Patients: A Meta-Analysis.
    Mirhosseini N; Vatanparast H; Mazidi M; Kimball SM · The Journal of clinical endocrinology and metabolism · 2017
    Meta-analysis1,528 participants24 studies pooledMetabolism Boost forVitamin D
  24. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  25. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  26. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3