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Sublingual Liquid B Complex

Nature's Bounty
4.8
★ ★ ★ ★ ★
(1408 ratings)
Vitamin B12 1200 mcg
Vitamin B5 30 mg
Product Image
Score79
A convenient liquid with several useful B vitamins and active riboflavin. Very high cyanocobalamin and an incomplete B-complex profile are the main drawbacks.
How scoring works
Quantity:2 Fluid Ounce(s) • (59 servings)
Goals:
Energy
General Health
Productivity Boost
Hair Health

Score 79

A convenient liquid with several useful B vitamins and active riboflavin. Very high cyanocobalamin and an incomplete B-complex profile are the main drawbacks.
How scoring works
$6.28($0.10 per serving)
Vitacost
$ 7.49
iHerb
$ 6.28
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Analysis

The blend supplies B12, B6, niacin, riboflavin, and pantothenic acid in a compact liquid. Riboflavin 5-phosphate is a useful form, and the serving is straightforward to measure.

B12 reaches 1,200 mcg as cyanocobalamin, which is far more than many routine users need. Missing thiamine, folate, and biotin mean the product is not a complete B-complex despite its name.

The product fits people who want a few key B vitamins in liquid form at low serving cost. Users seeking balanced B-vitamin coverage should choose a more complete formula.

Who is it for
  • Adults who prefer liquid supplements
  • Users seeking selected B vitamins rather than a complete complex
Best for
  • Low-cost liquid B-vitamin use
  • Avoiding tablets and capsules

Pros

  • Uses riboflavin 5-phosphate
  • Fully disclosed active amounts
  • Convenient sublingual liquid
  • Low serving cost

Cons

  • Omits several common B-complex nutrients
  • Uses cyanocobalamin
  • B12 amount is very high
  • Uses pyridoxine hydrochloride

Warnings

  • The 1,200 mcg B12 amount is far above basic daily needs and may be unnecessary for routine use.
  • Measure the liquid consistently to avoid accidental overuse.
  • People combining multiple B-complex products should account for the added niacin and vitamin B6.

Nutrient quality

84 Highest impact

The B vitamins form a coherent complex at generally meaningful amounts. Mixed form quality limits the formula compared with an all-active blend.

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Ingredient transparency

84 Highest impact

Active names and amounts are clearly stated, with no hidden proprietary dose. Complete intake directions and a full inactive-ingredient list are not included in the supplied data.

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Customer satisfaction

73 High impact

Supplied satisfaction metrics indicate a strong result with a meaningful response pool. Detailed experience themes are absent, so recurring complaints and real-world purpose fit remain uncertain.

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Value for money

71 High impact

Serving value appears moderate relative to the disclosed form and amount. The focused formula avoids low-value extras.

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Report analysis

Goals

Energy
Energy
Impact
Highest effect
A Goal FitA- Strength of SupportC+ CoverageA Formula Quality
Vitamin B5 · 30 mgRiboflavin · 1.7 mgVitamin B12 · 1200 mcg

A broad B-vitamin mix supports food-to-energy metabolism, with a high vitamin B12 amount and active riboflavin phosphate. Sublingual liquid delivery may suit people who avoid tablets.

Cyanocobalamin is less preferred than methylcobalamin, but all key active amounts are clearly disclosed. The formula strongly supports metabolic cofactors without providing acute alertness or adaptogenic coverage.

Study evidence
Riboflavin Mixed 6 studies
Vitamin B12 Disputed 14 studies
General Health
General Health
Impact
Highest effect
A- Goal FitA- Strength of SupportB- CoverageA- Formula Quality
Vitamin B12 · 1200 mcg

The liquid B-vitamin blend supports energy metabolism, nerve function, and normal red blood cell production. A substantial B12 amount and sublingual delivery may suit people who have difficulty swallowing tablets.

Cyanocobalamin is less bioactive than preferred B12 forms, but the exact amount is clear. The formula is focused and economical, though it leaves out several B vitamins and does not provide broad mineral or essential-fat support.

Study evidence
Vitamin B12 Adverse 66 studies
Productivity Boost
Productivity Boost
Impact
High effect
C+ Goal FitB Strength of SupportC- CoverageB+ Formula Quality
Vitamin B12 · 1200 mcgVitamin B12 · 1200 mcgVitamin B6 · 2 mg

High-dose B12 and companion B vitamins may support mental stamina when low status contributes to fatigue. Deficiency correction is well supported, but evidence for added productivity in people with adequate B-vitamin status is limited.

The 1,200 mcg B12 serving is substantial, while the other B vitamins provide useful foundational amounts. The B-complex design is coherent for nutritional energy support without conflicting ingredients.

Study evidence
Vitamin B12 Supportive 15 studies
Vitamin B12 No effect 17 studies
Hair Health
Hair Health
Impact
High effect
D+ Goal FitB+ Strength of SupportD CoverageB+ Formula Quality

High-dose B12 may support hair shedding caused by B12 deficiency, while the other B vitamins provide general follicle nutrition. Deficiency correction is well supported, but the blend has limited evidence for improving hair in replete users.

The 1,200 mcg B12 amount is substantial and companion B vitamins meet useful nutritional levels. The B-complex design is coherent for deficiency-oriented support without opposing ingredients.

Study evidence
Vitamin B12 Disputed 17 studies

Ingredients

IngredientAmount per serving
Riboflavin (Riboflavin 5'-Phosphate Sodium)
 1.7 mg
Niacin (Niacinamide)
 20 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 2 mg
Vitamin B12 (Cyanocobalamin)
 1200 mcg
Pantothenic Acid (Dexpanthenol)
 30 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free Vegetarian
Report overview
Vitamin B12 (Cyanocobalamin) · 1200 mcg OverallScore75
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The liquid supplies a high B12 dose with sublingual delivery. Cyanocobalamin is less aligned with the preferred bioactive forms, but the format may help people who avoid tablets. Strong active-dose efficiency supports its value.

View ingredientView products
Vitamin B5 (Dexpanthenol) · 30 mg OverallScore59
A- Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyF Value

Dexpanthenol is a specific provitamin B5 form that converts readily to pantothenic acid. The 30 mg dose meets basic needs but remains below the collection median for stronger metabolic support. Cost per equivalent 500 mg amount is poor despite the low serving cost.

View ingredientView products
Loading alternative details
89 Performance

Methyl B-12 1000 mcg & Methyl Folate 400 mcg plus P-5-P Lemon Flavor

Jarrow Formulas
<p>Methyl B-12 1000 mcg & Methyl Folate 400 mcg plus P-5-P Lemon Flavor offers a more purposeful option because it combines methylcobalamin with methylfolate and active B6. The active forms sharpen B12 and methylation support, but it omits the original riboflavin, niacin, and pantothenic acid coverage.</p>
84 Performance

Vitamin B12 5000 mcg

Global Healing
<p>Vitamin B12 5000 mcg offers a more purposeful option because it combines adenosylcobalamin, hydroxocobalamin, and methylcobalamin in a liquid. The active B12 form is easier to assess than the original cyanocobalamin, but the narrower formula does not replace the other B vitamins.</p>
87 Performance

B12 Energizer+ Natural Cherry Flavor

Advanced Nutrition by Zahler
<p>B12 Energizer+ Natural Cherry Flavor offers a more purposeful option because it supplies a clearly disclosed high amount of methylcobalamin. The active B12 form is easier to assess than the original cyanocobalamin, but the narrower formula does not replace the other B vitamins.</p>
86 Budget

Vitamin B12 2000 mcg

Nutricost
<p>Vitamin B12 2000 mcg costs less per serving, and it supplies 2,000 mcg methylcobalamin in a focused formula. The active B12 form is easier to assess than the original cyanocobalamin, but the narrower formula does not replace the other B vitamins.</p>
87 Budget

Fully Active B12 1500 mcg

Doctor's Best
<p>Fully Active B12 1500 mcg costs less per serving, and it supplies 1,500 mcg methylcobalamin in a focused formula. The active B12 form is easier to assess than the original cyanocobalamin, but the narrower formula does not replace the other B vitamins.</p>
87 Budget

B12 Methylcobalamin 1000 mcg

Natural Factors
<p>B12 Methylcobalamin 1000 mcg costs less per serving, and it supplies 1,000 mcg methylcobalamin in a focused formula. The active B12 form is easier to assess than the original cyanocobalamin, but the narrower formula does not replace the other B vitamins.</p>
86 Value

Quick Dissolve B-12 Methylcobalamin 2500 mcg

Nature's Bounty
<p>Quick Dissolve B-12 Methylcobalamin 2500 mcg pairs useful ingredient quality with favorable serving value because it supplies 2,500 mcg methylcobalamin in a quick-dissolve format. The active B12 form is easier to assess than the original cyanocobalamin, but the narrower formula does not replace the other B vitamins.</p>
85 Value

Sublingual Methylcobalamin 1000 mcg

Solgar
<p>Sublingual Methylcobalamin 1000 mcg pairs useful ingredient quality with favorable serving value because it supplies 1,000 mcg methylcobalamin in a sublingual format. The active B12 form is easier to assess than the original cyanocobalamin, but the narrower formula does not replace the other B vitamins.</p>
85 Value

Vegan B12 2500 mcg

DEVA
<p>Vegan B12 2500 mcg pairs useful ingredient quality with favorable serving value because it supplies 2,500 mcg methylcobalamin in a simple formula. The active B12 form is easier to assess than the original cyanocobalamin, but the narrower formula does not replace the other B vitamins.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  6. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  7. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  8. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  9. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  10. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  11. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsGeneral Health forVitamin B12
  12. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsGeneral Health forVitamin B12
  13. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsGeneral Health forVitamin B12
  14. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsGeneral Health forVitamin B12
  15. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsGeneral Health forVitamin B12
  16. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forVitamin B12
  17. Factors Associated with Premature Hair Graying in a Young Indian Population.
    Chakrabarty S; Krishnappa PG; Gowda DG; Hiremath J · International journal of trichology · 2016
    Case-control study74 participantsHair Health forVitamin B12
  18. Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
    İritaş SY · Dermatology practical & conceptual · 2026
    Case-control study600 participantsHair Health forVitamin B12
  19. Hair Loss After Laparoscopic Sleeve Gastrectomy.
    Katsogridaki G; Tzovaras G; Sioka E; Perivoliotis K; Zachari E; Magouliotis D; Tasiopoulou V; Chatedaki C; Zacharoulis D · Obesity surgery · 2019
    Cohort study50 participantsHair Health forVitamin B12
  20. Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.
    Sonthalia S; Priya A; Tobin DJ · Indian journal of dermatology · 2022
    Cross-sectional study71 participantsHair Health forVitamin B12
  21. Effects of Folic Acid and Vitamin B12, Alone and in Combination on Cognitive Function and Inflammatory Factors in the Elderly with Mild Cognitive Impairment: A Single-blind Experimental Design.
    Ma F; Zhou X; Li Q; Zhao J; Song A; An P; Du Y; Xu W; Huang G · Current Alzheimer research · 2020
    Randomized trial240 participantsProductivity Boost forVitamin B12
  22. Effects of Physical Activity and Micronutrients on Cognitive Performance in Children Aged 6 to 11 Years: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Meli AM; Ali A; Mhd Jalil AM; Mohd Yusof H; Tan MMC · Medicina (Kaunas, Lithuania) · 2022
    Meta-analysisProductivity Boost forVitamin B12
  23. Cognitive function in an elderly population: interaction between vitamin B12 status, depression, and apolipoprotein E ε4: the Hordaland Homocysteine Study.
    Vogiatzoglou A; Smith AD; Nurk E; Drevon CA; Ueland PM; Vollset SE; Nygaard HA; Engedal K; Tell GS; Refsum H · Psychosomatic medicine · 2013
    Cross-sectional study1,935 participantsProductivity Boost forVitamin B12
  24. Cognitive profile and inflammatory markers in children and adolescents with specific learning disorder: a cross-sectional study.
    Balatacı U; Ay B · Frontiers in pediatrics · 2026
    Case-control study108 participantsProductivity Boost forVitamin B12
  25. Association between vitamin B12 levels and cognitive impairment in older adults.
    Aguilar-Navarro SG; Carbajal-Silva JC; Palacios-Hernández MGI; Gutiérrez-Gutierrez LA; Ávila-Funes JA; Mimenza-Alvarado AJ · Gaceta medica de Mexico · 2023
    Cross-sectional study241 participantsProductivity Boost forVitamin B12
  26. Effects of vitamin B12 on performance and circadian rhythm in normal subjects.
    Mayer G; Kröger M; Meier-Ewert K · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 1997
    Randomized trial20 participantsProductivity Boost forVitamin B12
  27. Prenatal vitamin B12 status and cognitive functioning in children at 4 years of age: The ECLIPSES Study.
    Cruz-Rodríguez J; Canals-Sans J; Hernández-Martínez C; Voltas-Moreso N; Arija V · Maternal & child nutrition · 2023
    Cohort study249 participantsProductivity Boost forVitamin B12
  28. Dietary intakes and biomarker patterns of folate, vitamin B6, and vitamin B12 can be associated with cognitive impairment by hypermethylation of redox-related genes NUDT15 and TXNRD1.
    An Y; Feng L; Zhang X; Wang Y; Wang Y; Tao L; Qin Z; Xiao R · Clinical epigenetics · 2020
    Cohort study2,533 participantsProductivity Boost forVitamin B12
  29. Homocysteine, folate, and vitamins B6 and B12 blood levels in relation to cognitive performance: the Maine-Syracuse study.
    Elias MF; Robbins MA; Budge MM; Elias PK; Brennan SL; Johnston C; Nagy Z; Bates CJ · Psychosomatic medicine · 2008
    Cross-sectional study812 participantsProductivity Boost forVitamin B12