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Melatonin 3 mg

Life Extension
4.7
★ ★ ★ ★ ★
(6727 ratings)
Melatonin 3 mg
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Score85
A straightforward 3 mg capsule for sleep initiation, with limited overnight coverage and only indirect relevance to broader health goals.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Sleep Support
General Health
Immunity
Brain Health

Score 85

A straightforward 3 mg capsule for sleep initiation, with limited overnight coverage and only indirect relevance to broader health goals.
How scoring works
$7.50($0.12 per serving)
Pure Formulas
$ 7.50
Vitacost
$ 7.97
Vitacost
$ 7.83
Amazon
$ 7.50
iHerb
$ 7.50
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Analysis

A 3 mg melatonin serving is commonly used for falling asleep and circadian alignment. The single-active capsule makes the amount transparent and avoids a crowded formula.

Immediate delivery has no special role in repeated nighttime waking or early awakening. It also does not directly address memory, focus, immune nutrition, or other broad health pathways.

The product fits adults wanting a conventional sleep-onset capsule rather than a multi-ingredient blend. Sensitive users may still find 3 mg more than needed and should judge the dose by morning alertness as well as bedtime effect.

Who is it for
  • Adults seeking a conventional 3 mg melatonin capsule
  • People whose main concern is falling asleep
Best for
  • Sleep-onset and circadian support
  • A simple 60-serving routine

Pros

  • Clearly provides 3 mg of melatonin
  • Uses a focused single-active formula
  • Offers 60 servings

Cons

  • No sustained-release feature is shown
  • May be more than dose-sensitive users need
  • Broader brain and immune relevance is indirect

Warnings

  • Melatonin can cause drowsiness or next-day grogginess, so it should not be taken before driving or another task that requires alertness.

Nutrient quality

92 Highest impact

Standard oral delivery suits sleep onset but offers no overnight-release feature. The practical amount supports sleep without obvious excess.

Ingredient transparency

84 Highest impact

The shown active ingredients have clear amounts and no proprietary blend hides a key dose. Daily directions and a complete inactive-ingredient list are not supplied.

Customer satisfaction

71 High impact

The supplied aggregate rating is favorable and supported by a very large review volume. Detailed feedback is unavailable, so repeated complaints and fit with the intended use cannot be judged.

Value for money

90 Highest impact

The formula provides strong practical value for its dose and delivery features. The focused active profile preserves category competitiveness.

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Goals

Sleep Support
Impact
Highest effect
A+ Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Melatonin · 3 mg

Melatonin directly supports circadian timing and can help shorten the time needed to fall asleep. The 3 mg amount is clearly disclosed and fits a commonly used sleep-onset range.

Standard immediate-release capsule delivery is straightforward for sleep initiation. It does not provide sustained release for repeated nighttime waking or early awakening.

Study evidence
Melatonin Supportive 181 studies
General Health
Impact
High effect
B- Goal FitA- Strength of SupportD+ CoverageA Formula Quality

The melatonin amount is well suited to occasional sleep-onset and circadian support. Better sleep timing may contribute to daily well-being, but the formula does not address broader nutritional needs.

The dose is clear and convenient in one capsule. Immediate release may help with falling asleep but does not specifically support sleep maintenance.

Study evidence
Melatonin Supportive 69 studies
Immunity
Impact
Moderate effect
D+ Goal FitC Strength of SupportF CoverageA Formula Quality

Melatonin may support immunity indirectly through restorative sleep and has some immune-signaling activity, but it is not a primary immune nutrient. The 3 mg amount is clearly disclosed in a standard capsule intended mainly for sleep support.

The single-ingredient design is focused but covers only one indirect pathway. The amount may cause next-morning drowsiness in sensitive users, so it should not be taken before driving.

Study evidence
Melatonin Supportive 10 studies
Brain Health
Impact
Moderate effect
D- Goal FitC+ Strength of SupportF CoverageA Formula Quality

Melatonin supports circadian timing and sleep, which can indirectly affect cognitive function. A clearly disclosed 3 mg amount is active for sleep but does not directly target memory, focus, or neuroprotection.

The single-active capsule is easy to assess and free from unrelated additions. Melatonin may cause next-day drowsiness or vivid dreams, and this amount can be more than some sensitive users need.

Study evidence
Melatonin Supportive 29 studies

Ingredients

IngredientAmount per serving
Melatonin
3 mg
Gluten Free Adults 18–50
Report overview
Melatonin · 3 mg OverallScore69
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA- Value

The 3 mg dose aligns well with physiological sleep support and is clearly provided in one capsule. Standard capsule delivery may support sleep onset but offers no sustained-release benefit for staying asleep. Value is favorable, while no independent purity certification is supplied.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.
    Sletten TL; Magee M; Murray JM; Gordon CJ; Lovato N; Kennaway DJ; Gwini SM; Bartlett DJ; Lockley SW; Lack LC; Grunstein RR; Rajaratnam SMW; Delayed Sleep on Melatonin (DelSoM) Study Group · PLoS medicine · 2019
    Randomized trial116 participantsSleep Support forMelatonin
  3. Comparative Efficacy, Tolerability, and Acceptability of Donanemab, Lecanemab, Aducanumab, Melatonin, and Aerobic Exercise for a Short Time on Cognitive Function in Mild Cognitive Impairment and Mild Alzheimer's Disease: A Systematic Review and Network Meta-Analysis.
    Terao I; Kodama W · Journal of Alzheimer's disease : JAD · 2024
    Meta-analysis4,599 participants10 studies pooledBrain Health forMelatonin
  4. Melatonin for sleep and cognitive outcomes in older adults with cognitive impairment: a meta-analysis of randomised controlled trials.
    Mdluli NT; Banda KJ; Chang YC · Age and ageing · 2025
    Meta-analysis516 participants10 studies pooledBrain Health forMelatonin
  5. Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer's disease: a 6-month, randomized, placebo-controlled, multicenter trial.
    Wade AG; Farmer M; Harari G; Fund N; Laudon M; Nir T; Frydman-Marom A; Zisapel N · Clinical interventions in aging · 2015
    Randomized trial80 participantsBrain Health forMelatonin
  6. Early Oral Melatonin Supplementation Supports White Matter Maturation in Preterm Infants: Neuroprotective Insights of an Antioxidant Molecule.
    Garofoli F; Asteggiano C; Minniti ML; Accorsi P; Albertini R; Angelini M; Aversa S; Ballante E; Cabini RF; Caporali C; Cociglio S; Franco V; Longo S; Malerba L; Materia V; Mazzocchi L; Naboni C; Palmisani M; Pullega C; Pisoni C; Preda L; Riboli A; Risso FM; Rognone E; Savini G; Simoncelli AM; Villani P; Tzialla C; Pinelli L; Fazzi E; Chiapparini L; Borgatti R; Ghirardello S; Pichiecchio A; Orcesi S · Journal of pineal research · 2026
    Randomized trial54 participantsBrain Health forMelatonin
  7. Efficacy and Safety of Melatonin in Migraine Prophylaxis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Abouelmagd ME; Aldemerdash MA; Khatatbeh AA; Osman ASA; Abbas A; Allam S; AlEdani EM; Aldemerdash A; Monteith TS · Current pain and headache reports · 2026
    Meta-analysis788 participants9 studies pooledBrain Health forMelatonin
  8. Melatonin for preventing and treating jet lag.
    Herxheimer A; Petrie KJ · The Cochrane database of systematic reviews · 2001
    Systematic review10 studies pooledGeneral Health forMelatonin
  9. Pediatric Prolonged-Release Melatonin for Sleep in Children with Autism Spectrum Disorder: Impact on Child Behavior and Caregiver's Quality of Life.
    Schroder CM; Malow BA; Maras A; Melmed RD; Findling RL; Breddy J; Nir T; Shahmoon S; Zisapel N; Gringras P · Journal of autism and developmental disorders · 2019
    Randomized trial125 participantsGeneral Health forMelatonin
  10. Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials.
    Fatemeh G; Sajjad M; Niloufar R; Neda S; Leila S; Khadijeh M · Journal of neurology · 2022
    Meta-analysis23 studies pooledGeneral Health forMelatonin
  11. Efficacy of melatonin for chronic insomnia: Systematic reviews and meta-analyses.
    Choi K; Lee YJ; Park S; Je NK; Suh HS · Sleep medicine reviews · 2022
    Meta-analysis24 studies pooledGeneral Health forMelatonin
  12. Effectiveness of melatonin for the treatment of nocturia: a randomized controlled trial.
    Leerasiri P; Pariyaeksut P; Hengrasmee P; Asumpinwong C · International urogynecology journal · 2023
    Randomized trial60 participantsGeneral Health forMelatonin
  13. Exogenous melatonin boosts vaccine-induced immunity in individuals with high pre-existing influenza immunity.
    Oda K; Danko J; Villasante E; Bergmann-Leitner E; Lee R; Wijayalath W · Frontiers in immunology · 2025
    Randomized trialImmunity forMelatonin
  14. Evaluation of melatonin effectiveness in the adjuvant treatment of ulcerative colitis.
    Chojnacki C; Wisniewska-Jarosinska M; Walecka-Kapica E; Klupinska G; Jaworek J; Chojnacki J · Journal of physiology and pharmacology : an official journal of the Polish Physiological Society · 2012
    Randomized trial60 participantsImmunity forMelatonin
  15. Pineal-opioid system interactions in the control of immunoinflammatory responses.
    Lissoni P; Barni S; Tancini G; Fossati V; Frigerio F · Annals of the New York Academy of Sciences · 1995
    Clinical trial130 participantsImmunity forMelatonin
  16. Influenza vaccine response is predicted by chronotype and differentially associated with pre- and post-vaccination sleep.
    Harrison EM; Lee RU; Porter CK; Isidean SD; Easterling AP; White L; Boulifard DA; DeTizio K; Liang Z; Sedegah M; Danko J; Glickman GL · Brain, behavior, & immunity - health · 2026
    Randomized trialImmunity forMelatonin
  17. Mechanisms and clinical evidence to support melatonin's use in severe COVID-19 patients to lower mortality.
    Tan DX; Reiter RJ · Life sciences · 2022
    Narrative review19 participantsImmunity forMelatonin
  18. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  19. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  20. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  21. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin