Product Image

Cal-Snack Calcium Magnesium Vanilla Orange Flavor

4.3
★ ★ ★ ★ ★
(129 ratings)
Calcium 1000 mg
Magnesium 500 mg
Product Image
Score58
Better package value helps this chewable option, but confusing totals, basic mineral forms, and very low vitamin D2 keep it mediocre.
How scoring works
Wafer
Quantity:120 Wafer(s) • (60 servings)
Goals:
Energy
Bone Health
General Health
Heart Health

Score 58

Better package value helps this chewable option, but confusing totals, basic mineral forms, and very low vitamin D2 keep it mediocre.
How scoring works

Also available as

1 option
60 servings Calcium 1000 mg, Magnesium 500 mg • 60 Wafer(s) • 30 servings $21.69 ($0.72 per serving)
$31.49($0.52 per serving)
iHerb
$ 31.49
Vitacost
$ 31.49
Report prices

Analysis

Calcium citrate and magnesium aspartate improve a formula that also includes carbonate and oxide. The chewable vanilla-orange format may be easier than swallowing several tablets.

Repeated calcium and magnesium quantities leave the true elemental totals uncertain. Vitamin D2 is supplied at only a small amount and is less preferred than D3.

The larger package improves value compared with the smaller wafer bottle. Four grams of carbohydrate per serving and unclear mineral exposure remain meaningful drawbacks.

Who is it for
  • Adults preferring flavored chewable minerals
  • Users wanting a longer-lasting wafer package
Best for
  • Pill-free calcium and magnesium
  • Chewable mineral supplementation

Pros

  • Includes citrate and aspartate forms
  • Accessible chewable format
  • Larger bottle improves serving value

Cons

  • Mineral totals are unclear
  • Includes carbonate and oxide forms
  • Vitamin D2 contribution is minimal

Warnings

  • The potentially substantial magnesium amount may cause diarrhea or cramping
  • Check total calcium exposure against dietary intake because the repeated label amounts are unclear
  • Separate calcium from thyroid hormone, bisphosphonates, and certain antibiotics

Nutrient quality

54 Moderate impact

Citrate and aspartate improve the blend, but carbonate, magnesium oxide, and ergocalciferol are less favorable forms, and the 1,000 mg calcium amount is too concentrated for one sitting, and 500 mg magnesium is also aggressive for some users. The concentrated calcium and magnesium amounts may reduce absorption efficiency and digestive comfort, while the minerals fit bone support, but the sweetened wafer format adds little nutritional benefit.

.

Ingredient transparency

69 High impact

Total mineral amounts are shown, but repeated amounts across forms make each form contribution unclear, and no proprietary blend hides the amount of a listed core mineral. Serving count is supplied, but complete daily-use directions are not provided, while inactive ingredients and excipients are not included in the supplied label details.

.

Customer satisfaction

59 Moderate impact

The supplied average rating is modest relative to competing products, and the limited review count reduces confidence in the average rating. Specific review themes are unavailable, so repeated negatives and real-world fit remain uncertain.

.

Value for money

46 Lower impact

Weak forms or concentrated dosing make the formula difficult to justify on quality alone, and the high serving cost weakens value relative to similar mineral formulas. The wafer adds carbohydrate and flavoring overhead without improving the mineral profile, while form, dose, or serving-value limitations make it less competitive than similar products.

.
Report analysis

Goals

Energy
Energy
Impact
High effect
A Goal FitB- Strength of SupportC+ CoverageB Formula Quality
Vitamin D · 1.25 mcgMagnesium · 500 mg

Calcium and magnesium provide meaningful mineral coverage for skeletal, muscular, and metabolic functions. The formula mixes better-absorbed citrate or aspartate with lower-quality carbonate and oxide forms, while the vitamin D amount is too small to add much support.

The wafer format adds carbohydrate and makes the formula less streamlined than a simple tablet or capsule. The high magnesium amount may cause loose stools or abdominal discomfort, especially because part of it comes from magnesium oxide.

Study evidence
Magnesium Supportive 4 studies
Vitamin D Supportive 32 studies
Bone Health
Bone Health
Impact
High effect
B+ Goal FitC+ Strength of SupportC+ CoverageB+ Formula Quality
Magnesium · 500 mgCalcium · 1000 mgVitamin D · 1.25 mcg

Calcium and magnesium provide substantial structural and remodeling minerals, while vitamin D offers only a token amount and uses D2. Citrate and aspartate improve the mineral mixes, but carbonate and oxide lower average absorption quality.

The 1,000 mg calcium serving is larger than the body generally absorbs efficiently at once, and 500 mg supplemental magnesium may cause digestive upset. The formula lacks vitamin K2 and organic matrix support, leaving calcium placement and flexibility pathways incomplete.

Study evidence
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Vitamin D Supportive 202 studies
General Health
General Health
Impact
High effect
B+ Goal FitC+ Strength of SupportC CoverageB- Formula Quality
Vitamin D · 1.25 mcgMagnesium · 500 mg

Calcium and magnesium provide foundational support for bones, muscles, nerves, and normal energy metabolism. Both mineral amounts are substantial, making the formula more useful for a defined intake gap than as a broad daily wellness product.

Magnesium oxide and calcium carbonate reduce the quality of the otherwise mixed-form mineral blend, while the vitamin D2 amount is very small. The large calcium and magnesium serving may cause constipation, loose stools, or reduced absorption of thyroid medicine and certain antibiotics when taken at the same time.

Study evidence
Magnesium Supportive 114 studies
Vitamin D Supportive 115 studies
Heart Health
Heart Health
Impact
High effect
B- Goal FitB Strength of SupportC- CoverageC+ Formula Quality
Magnesium · 500 mgVitamin D · 1.25 mcg

Magnesium provides relevant support for heart rhythm and vascular tone at a substantial 500 mg amount. Aspartate adds a useful form, but oxide is also present and the contribution from each form is unclear.

A 1,000 mg calcium amount makes the wafers more focused on bone-mineral nutrition than cardiovascular support, while the small vitamin D2 amount adds little. Substantial calcium and magnesium may cause digestive discomfort and require caution in people with impaired kidney function.

Study evidence
Magnesium Supportive 158 studies
Stress Relief
Stress Relief
Impact
Moderate effect
C+ Goal FitC+ Strength of SupportC- CoverageC- Formula Quality
Vitamin D · 1.25 mcgMagnesium · 500 mg

Magnesium provides relevant foundational support for nervous-system regulation and may help with stress-related tension. The disclosed amount appears substantial enough to contribute meaningfully.

The aspartate and oxide blend has mixed absorption, with oxide limiting form quality. Added calcium contributes little direct stress support and makes the formula less focused.

Study evidence
Magnesium Supportive 13 studies
Cardiovascular Support
Cardiovascular Support
Impact
Moderate effect
B- Goal FitC+ Strength of SupportD CoverageF Formula Quality
Magnesium · 500 mgVitamin D · 1.25 mcg

Magnesium supports vascular tone and normal cardiac rhythm, giving it a direct but narrow cardiovascular role. Human evidence supports magnesium for blood-pressure and rhythm support, especially when intake is inadequate.

The disclosed magnesium amount is substantial and reaches a commonly used supplemental range. Magnesium aspartate is paired with poorly absorbed oxide, and vitamin D uses the less preferred D2 form.

Study evidence
Magnesium Supportive 123 studies
Vitamin D Mixed 170 studies

Ingredients

IngredientAmount per serving
Calories
20 Calorie(s)
Total Carbohydrates
4 Gram(s)
Vitamin D (Ergocalciferol)
 1.25 mcg
Calcium (Calcium Carbonate, Calcium Citrate)
 1000 mg
Magnesium (Magnesium Aspartate, Magnesium Oxide)
 500 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
Calcium (Calcium Carbonate, Calcium Citrate) · 1000 mg OverallScore56
B Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyD+ Value

The wafer combines citrate and carbonate at a high 1,000 mg serving. Mixed forms offer some absorption benefit, but the large dose and carbohydrate content reduce efficiency and purity. Moderate cost produces average value.

View ingredientView products
Magnesium (Magnesium Aspartate, Magnesium Oxide) · 500 mg OverallScore52
F Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value
+1

The label clearly states magnesium, but the blend combines moderate-absorption aspartate with poorly absorbed oxide. Vitamin D adds useful bone-health support, while the calcium level does not exceed the stated competition threshold. The above-median serving cost weakens value for a mixed-quality source.

View ingredientView products
Loading alternative details
94 Performance

Cal/Mag 500 mg/250 mg

NaturesPlus
<p>Chelated calcium and magnesium provide a balanced, focused mineral formula with stronger form quality than products relying heavily on carbonate or oxide. The simple serving is easy to assess, though vitamin D and vitamin K are not included.</p>
92 Performance

Magnesium Bisglycinate Chelate

Healthy Origins
<p>TRAACS magnesium bisglycinate provides a well-absorbed form at a useful amount and avoids the weaker oxide forms found in many combinations. The powder covers magnesium only, so a separate calcium source is needed when both minerals are intended.</p>
92 Performance

Calcium Citrate Pure Powder

NOW
<p>Calcium citrate provides a well-absorbed, clearly disclosed calcium source in an adjustable powder. The focused formula omits magnesium, vitamin D, and vitamin K, so it works better as a targeted calcium option than as a complete replacement.</p>
87 Budget

600 Calcium Supplement

21st Century
<p>A straightforward calcium carbonate tablet provides a much lower-cost source of calcium at a practical supplemental amount. Carbonate works best with food, and the formula omits magnesium, vitamin D, and other bone-supporting cofactors found in broader products.</p>
86 Budget

Calcium Carbonate

NOW
<p>A pure calcium carbonate powder offers substantial calcium with excellent serving value and no unrelated actives. Food and stomach acid aid carbonate absorption, while the calcium-only design leaves magnesium and vitamin D uncovered.</p>
85 Budget

Calcium 600 with Vitamin D3

Nature's Bounty
<p>Calcium with vitamin D3 provides an economical, meaningfully dosed bone-support pairing. Calcium carbonate is best taken with food, and the formula does not replace the original magnesium coverage.</p>
94 Value

Krebs Magnesium Potassium Complex

Nature's Way
<p>Magnesium lysinate and malate provide favorable forms at a useful amount, with modest potassium adding complementary mineral support. Serving value is strong, but the formula requires a separate calcium source when calcium is also needed.</p>
90 Value

Calcium Citrate +D3 Petites

21st Century
<p>Calcium citrate with vitamin D3 combines a practical amount, favorable absorption, and accessible serving value. The focused formula does not provide magnesium, and missing excipient details modestly limit transparency.</p>
88 Value

Albion Chelated Calcium 180 mg

Swanson Ultra
<p>Calcium glycinate chelate with a small vitamin D3 addition offers a useful balance of form quality and value. The supplied product name and serving amount conflict, so the current label should be checked, and magnesium still needs separate coverage.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  2. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  3. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  4. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  5. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  6. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  7. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  8. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  9. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  10. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  11. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  12. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  13. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  14. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  15. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  16. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  17. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  18. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  19. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium Cardiovascular Support forVitamin D
  20. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  21. A Randomized Trial of Vitamin D Supplementation on Vascular Function in CKD.
    Kumar V; Yadav AK; Lal A; Kumar V; Singhal M; Billot L; Gupta KL; Banerjee D; Jha V · Journal of the American Society of Nephrology : JASN · 2017
    Randomized trial120 participantsCardiovascular Support forVitamin D
  22. Randomized, placebo-controlled, double-blind clinical trial on the contributions of vitamin D in the control of cardiovascular risk factors, depressive symptoms and suicide risk.
    Porto C; Petribu K; Barbosa N; Magalhães R; Lira C; Porto AB; Markman-Filho B; Lordsleem A; Calado E; Magalhães J; Sougey E; Silva T; Junio A; Bandeira F; Leão R · American heart journal plus : cardiology research and practice · 2025
    Randomized trial224 participantsCardiovascular Support forVitamin D
  23. Dose responses of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency: A placebo controlled randomized trial.
    Raed A; Bhagatwala J; Zhu H; Pollock NK; Parikh SJ; Huang Y; Havens R; Kotak I; Guo DH; Dong Y · PloS one · 2017
    Randomized trial70 participantsCardiovascular Support forVitamin D
  24. Paricalcitol and endothelial function in chronic kidney disease trial.
    Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
    Randomized trial88 participantsCardiovascular Support forVitamin D
  25. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  26. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  27. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  28. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  29. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  30. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  31. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  32. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  33. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  34. Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
    López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
    Meta-analysis345 participants5 studies pooledEnergy forVitamin D
  35. Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
    Randomized trial40 participantsEnergy forVitamin D
  36. Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
    Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
    Randomized trial91 participantsEnergy forVitamin D
  37. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
    Elfituri S · Reumatologia · 2024
    Randomized trial68 participantsEnergy forVitamin D
  38. The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
    Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
    Randomized trial40 participantsEnergy forVitamin D
  39. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  40. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  41. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  42. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  43. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  44. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  45. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  46. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  47. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  48. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  49. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  50. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  51. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  52. Predictive Model of Nail Consistency Using Scanning Electron Microscopy with Energy-Dispersive X-Ray.
    Mingorance Álvarez E; Martínez Quintana R; Pérez Pico AM; Mayordomo R · Biology · 2021
    Cross-sectional study57 participantsNail Health forCalcium
  53. Recommendations for the definition, evaluation, and treatment of nail psoriasis in adult patients with no or mild skin psoriasis: A dermatologist and nail expert group consensus.
    Rigopoulos D; Baran R; Chiheb S; Daniel CR; Di Chiacchio N; Gregoriou S; Grover C; Haneke E; Iorizzo M; Pasch M; Piraccini BM; Rich P; Richert B; Rompoti N; Rubin AI; Singal A; Starace M; Tosti A; Triantafyllopoulou I; Zaiac M · Journal of the American Academy of Dermatology · 2019
    Guideline / consensusNail Health forVitamin D
  54. Vitamins for the Management of Nail Disease: A Literature Review.
    Curtis KL; Lipner SR · Skin appendage disorders · 2025
    Narrative reviewNail Health forVitamin D
  55. Nail involvement in psoriatic arthritis.
    Sobolewski P; Walecka I; Dopytalska K · Reumatologia · 2019
    Narrative reviewNail Health forVitamin D
  56. Psoriasis treatment in difficult locations: scalp, nails, and intertriginous areas.
    Wozel G · Clinics in dermatology · 2009
    Narrative reviewNail Health forVitamin D
  57. Nail psoriasis: clinical presentation and best practice recommendations.
    Edwards F; de Berker D · Drugs · 2010
    Narrative reviewNail Health forVitamin D
  58. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  59. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  60. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  61. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  62. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  63. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  64. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  65. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  66. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  67. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium
  68. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsTestosterone Support forVitamin D
  69. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsTestosterone Support forVitamin D
  70. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsTestosterone Support forVitamin D
  71. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
  72. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsTestosterone Support forVitamin D