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Zinc Picolinate 22 mg

Swanson
4.9
★ ★ ★ ★ ★
(28715 ratings)
Zinc 22 mg
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Score87

A well-absorbed picolinate form and practical amount make this suitable for routine zinc support. It remains a narrow single-nutrient option.

How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Immunity
General Health
Testosterone Support
Skin Health
Hair Health

Score 87

A well-absorbed picolinate form and practical amount make this suitable for routine zinc support. It remains a narrow single-nutrient option.

How scoring works
$9.79($0.16 per serving)
Walmart
$ 9.79
iHerb
$ 9.79
iHerb
$ 9.79
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Analysis

Zinc picolinate is a well-absorbed form, and the 22 mg serving is clearly disclosed. The amount is meaningful without crossing the adult upper intake level.

The capsule suits people looking to support zinc status for immune, skin, hair, or hormone-related needs. Benefits are most plausible when food intake or baseline zinc status is inadequate.

No copper or complementary nutrients are present, so the product remains targeted rather than comprehensive. Extended use should account for zinc from food and other supplements.

Who is it for
  • Adults seeking a well-absorbed daily zinc capsule
  • People with inadequate dietary zinc intake
Best for
  • Routine targeted zinc support
  • Immune and skin support when zinc intake is low

Pros

  • Uses zinc picolinate
  • Amount stays below the adult upper intake level
  • Active form and quantity are fully disclosed
  • Favorable value for the form

Cons

  • Does not include copper
  • Offers no broader vitamin or mineral coverage
  • Benefits may be limited when zinc status is already adequate

Warnings

  • 22 mg may cause nausea when taken on an empty stomach.
  • Long-term use alongside other zinc supplements can reduce copper absorption, so total zinc intake matters.
  • Zinc can reduce absorption of tetracycline or quinolone antibiotics, so dose spacing should follow the medicine instructions.

Nutrient quality

94 Highest impact

Zinc picolinate is a well-regarded form with favorable absorption. The amount stays within a practical maintenance range for most adults.

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Ingredient transparency

83 Highest impact

The elemental amount and picolinate form are stated clearly. Directions and inactive ingredients are not supplied, limiting full label transparency.

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Customer satisfaction

74 High impact

The supplied aggregate rating indicates exceptionally strong customer satisfaction. Specific comments are unavailable, so complaint patterns and intended-use fit cannot be verified.

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Value for money

95 Highest impact

A premium form and low serving cost create strong value. The simple dose and label compare well within the category.

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Report analysis

Goals

Immunity
Immunity
Impact
Highest effect
A Goal FitA+ Strength of SupportC CoverageA+ Formula Quality
Zinc · 22 mg

Zinc picolinate supplies a well-absorbed immune nutrient at a meaningful maintenance amount. Zinc directly supports immune-cell development, signaling, and normal protective barriers.

The single-mineral design does not cover vitamin D, vitamin C, or antioxidant pathways. Continuous use alongside other zinc products may reduce copper absorption, so total long-term zinc intake matters.

Study evidence
Zinc Supportive 73 studies
General Health
General Health
Impact
Highest effect
A Goal FitA Strength of SupportC CoverageA+ Formula Quality
Zinc · 22 mg

Zinc picolinate provides a well-absorbed form of a foundational mineral involved in immune readiness, DNA synthesis, and many enzyme reactions. The 22 mg amount is clearly disclosed and can meaningfully support people whose intake is inadequate.

The focused formula does not cover other major nutritional gaps, so it works better as targeted support than a complete wellness product. Long-term daily use without copper may contribute to copper depletion, especially when other zinc sources raise total intake.

Study evidence
Zinc Supportive 60 studies
Testosterone Support
Testosterone Support
Impact
Highest effect
B+ Goal FitA Strength of SupportC CoverageA Formula Quality
Zinc · 22 mg

The well-absorbed zinc form and meaningful amount provide solid foundational support for testosterone production, especially when zinc intake is low. Zinc alone cannot address stress regulation or free-hormone pathways.

The clearly stated amount makes the formula easy to assess and avoids uncertainty from a blend. Long-term daily use at this amount may reduce copper absorption, so people using other zinc products should consider their total intake.

Study evidence
Zinc Disputed 7 studies
Skin Health
Skin Health
Impact
High effect
B Goal FitA Strength of SupportD+ CoverageA+ Formula Quality
Zinc · 22 mg

Zinc supports normal skin repair, inflammation control, and antioxidant defenses. Evidence is most relevant when low zinc intake or status is limiting normal repair.

The 22 mg amount is substantial for routine support, and zinc picolinate is a highly absorbable form with clear disclosure. Copper is not included, but this moderate amount poses less balance concern than higher-dose zinc when other zinc sources are limited.

Study evidence
Zinc Supportive 66 studies
Hair Health
Hair Health
Impact
High effect
B Goal FitA- Strength of SupportD+ CoverageA- Formula Quality
Zinc · 22 mg

Zinc picolinate supplies a well-absorbed mineral form that may support follicles when zinc intake is low. The moderate amount and clear label make the contribution credible without relying on a large blend.

The product does not cover structural proteins, iron status, or hormonal causes of thinning. Prolonged daily zinc use can reduce copper absorption, so total zinc and copper intake matter over time.

Study evidence
Zinc Supportive 22 studies

Ingredients

IngredientAmount per serving
Zinc (Zinc Picolinate)
 22 mg
Adults 18–50
Report overview
Zinc (Zinc Picolinate) · 22 mg OverallScore90
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value

Zinc picolinate provides a highly absorbable form suited to routine supplementation. The moderate dose supports maintenance while keeping copper-depletion risk relatively low even without added copper. The serving cost remains favorable for the premium form.

View ingredientView products
Loading alternative details
81 Performance

Zinc Picolinate 22 mg

Solgar
Strong zinc-form quality and a practical dose make this a more dependable routine option than the original. Picolinate offers strong absorption potential at a useful maintenance amount. The focused formula and very low serving cost make it a practical choice without an obvious dosing excess.
81 Performance

Chelated Zinc 30 mg

Swanson
Strong zinc-form quality and a practical dose make this a more dependable routine option than the original. A branded glycinate chelate offers excellent absorption potential at a substantial amount. The simple capsule is highly economical, though sustained use without copper may impair mineral balance.
80 Performance

Zinc Chelate 30 mg

Nature's Way
Strong zinc-form quality and a practical dose make this a more dependable routine option than the original. Zinc bisglycinate provides a well-absorbed form at a robust daily amount. The focused capsule is clearly labeled and very inexpensive, but no copper is included.
82 Budget

L-OptiZinc 30 mg

NOW
Lower recurring cost makes this a more economical zinc option than the original while retaining a clearly characterized active profile. Zinc monomethionine provides excellent absorption potential at a substantial amount. A small copper addition is helpful but remains too low to fully balance sustained high zinc use.
82 Budget

Zinc Picolinate 25 mg

Thompson
Lower recurring cost makes this a more economical zinc option than the original while retaining a clearly characterized active profile. Picolinate is a well-absorbed zinc form, and the amount is meaningful without crossing the usual adult upper limit. The simple formula and very low serving cost make it a practical zinc supplement.
82 Budget

Zinc 30 mg

Nature's Life
Lower recurring cost makes this a more economical zinc option than the original while retaining a clearly characterized active profile. Zinc picolinate with copper provides a coherent, economical mineral-balance formula. The zinc amount is substantial, and repeated copper entries make the total less clear than it should be.
90 Value

OptiZinc

Source Naturals
The combination of form quality, practical dosing, and serving value provides a stronger quality-to-cost balance than the original. Zinc methionine provides a well-absorbed chelated form at a robust amount, and added copper offers partial balance. The copper amount is small relative to the zinc, but the formula is safer for sustained use than unbalanced high-dose options.
89 Value

Chelated Zinc 30 mg

Carlson
The combination of form quality, practical dosing, and serving value provides a stronger quality-to-cost balance than the original. Glycinate chelate offers high-quality absorption and tolerance at a robust amount. Zinc glycinate chelate is a highly regarded form for absorption and tolerance.
86 Value

Zinc 30 mg

Nature Made
The combination of form quality, practical dosing, and serving value provides a stronger quality-to-cost balance than the original. Zinc gluconate provides a meaningful amount in a focused, very inexpensive tablet. It is suitable for targeted use, although prolonged daily intake at this level without copper may gradually disturb copper balance.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  2. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  3. Zinc for infection prevention in children with sickle cell anemia: a randomized double-blind placebo-controlled trial.
    Namazzi R; Opoka R; Conroy AL; Datta D; Tagoola A; Bond C; Goings MJ; Ryu MS; Cusick SE; Krebs NF; Jang JH; Tu W; Ware RE; John CC · Blood advances · 2023
    Randomized trial252 participantsImmunity forZinc
  4. Effects of Zinc Supplementation on Inflammatory Skin Diseases: A Systematic Review of the Clinical Evidence.
    Dhaliwal S; Nguyen M; Vaughn AR; Notay M; Chambers CJ; Sivamani RK · American journal of clinical dermatology · 2020
    Systematic review22 studies pooledSkin Health forZinc
  5. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  6. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forZinc
  7. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  8. Hair Loss and Zinc Deficiency: A Cross-Sectional Study.
    Liran O; Vered S; Cohen B; Shapiro Ben David S; Nakhleh A; Rahamim-Cohen D; Azuri J; Adler L · Healthcare (Basel, Switzerland) · 2025
    Cross-sectional study23,975 participantsHair Health forZinc
  9. Role of zinc in chronic telogen effluvium in serum and hair of patients with alopecia.
    Zufishan S; Haque Z; Nazar S; Afaq E; Aamir E; Rafique S · JPMA. The Journal of the Pakistan Medical Association · 2024
    Case-control study100 participantsHair Health forZinc
  10. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  11. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  12. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  13. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  14. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  15. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  16. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  17. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  18. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  19. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  20. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  21. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  22. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  23. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  24. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  25. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  26. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  27. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  28. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  29. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc