BioCoenzymated Methylfolate 1000 mcg
Natural Factors
Score 78
A high-potency active folate (5-MTHF) tablet with a complementary low dose of methylcobalamin B12, ideal for synergistic metabolic support.
Score 78
A high-potency active folate (5-MTHF) tablet with a complementary low dose of methylcobalamin B12, ideal for synergistic metabolic support.
Analysis
This Natural Factors product focuses on providing 1700 mcg DFE of active (6S)-5-Methyltetrahydrofolic Acid Glucosamine Salt, also known as 5-MTHF, which is the body's preferred and readily usable form of folate. It also includes a small, complementary dose of 50 mcg of methylcobalamin B12. This combination is highly beneficial because folate and B12 are critical cofactors in the methylation cycle, essential for DNA synthesis, cell division, and homocysteine metabolism.
While the B12 dose is relatively low for direct energy boosting, its inclusion is strategic to work synergistically with the high-potency folate, especially since active folate can sometimes mask a B12 deficiency if not supplemented. This makes it an excellent choice for those primarily seeking advanced folate support, with added B12 for comprehensive metabolic harmony. The tablet form is convenient for daily use.
Pros
- Features active 5-MTHF folate, directly usable by the body.
- Provides a substantial dose of folate (1700 mcg DFE).
- Includes methylcobalamin B12 for synergistic metabolic support.
- From a respected brand with a good customer review count.
Cons
- The B12 dose (50 mcg) is very low for those seeking primary B12 supplementation.
- Higher price per serving due to the active forms of nutrients.
- Might not be suitable for individuals only looking for high-dose B12.
Warnings
- Individuals taking certain medications, particularly for mood, seizures, or specific health conditions, should consult a healthcare professional due to folate interactions.
- High doses of folate can potentially mask a B12 deficiency; ensure B12 status is monitored if this is your primary B12 source.
$14.19($0.23 per serving)
 Vitacost | $ 14.19 | |
 iHerb | $ 15.37 | |
| iHerb | $ 15.37 |
Goals
Impact
Highest effect
This combination is exceptionally effective in maintaining healthy homocysteine levels, a critical factor for robust cardiovascular wellness.
Impact
Highest effect
Instrumental in supporting the maintenance of healthy homocysteine levels, directly contributing to heart health.
Impact
Highest effect
Active folate and B12 are crucial for neurotransmitter synthesis and brain health, offering strong support for cognitive functions.
Impact
Highest effect
The synergistic action of active folate and B12 is highly beneficial for nervous system health and processes that impact mood regulation.
Impact
Highest effect
This combination provides excellent support for nerve health, myelin maintenance, and overall brain function.
Impact
Highest effect
The synergistic action of active folate and B12 is fundamental for numerous physiological processes, offering broad support for general health.
Impact
Highest effect
Optimal levels of active folate and B12 are essential for robust brain function, which can directly enhance mental clarity and focus.
Impact
Highest effect
Active folate and B12 are essential for various metabolic pathways, providing strong support for overall metabolic function.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Folate | 1700 mcg DFE |
Vitamin B12 | 50 mcg |
Vitamin B12 75
While the B12 dose is modest, its active form combined with high-potency active folate offers synergistic B12-related benefits for metabolic support.
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