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Women's Multi 40+ Organic Berry

4.6
★ ★ ★ ★ ★
(6858 ratings)
Folate 120 mcg
Vitamin K 120 mcg
Product Image
Score68
A convenient vitamin gummy covers several basics, but weak folate, unclear vitamin K, and missing bone minerals limit its goal fit.
How scoring works
Quantity:120 Gummy(ies) • (30 servings)
Goals:
General Health
Bone Health
Anti-Aging
Heart Health

Score 68

A convenient vitamin gummy covers several basics, but weak folate, unclear vitamin K, and missing bone minerals limit its goal fit.
How scoring works

Also available as

1 option
Standard • 120 Gummy(ies) servings B9 400 mcg, K 120 mcg • 120 Gummy(ies) • 30 servings $26.59 ($0.88 per serving)
$26.59($0.88 per serving)
iHerb
$ 26.59
Pure Formulas
$ 26.59
Amazon
$ 26.59
Walmart
$ 26.59
Vitacost
$ 26.59
iHerb
$ 26.59
Vitacost
$ 27.69
Report prices

Analysis

The formula provides useful vitamin C, D3, vitamin E, B vitamins, and several trace minerals in a gummy format. Methylcobalamin is a favorable B12 choice for routine nutritional coverage.

Folate is supplied at a low amount without a named form. Vitamin K is present at a meaningful amount, but the missing K1 or K2 identity makes targeted bone and cardiovascular relevance uncertain.

The formula does not supply meaningful calcium or magnesium despite its bone-health positioning. Four gummies and a notable carbohydrate amount add inconvenience and reduce nutrient density.

Who is it for
  • Women over forty who prefer gummies
  • Adults seeking basic vitamin support
  • People unable to swallow tablets
Best for
  • General vitamin backup
  • Vitamin C and D3 intake
  • Methylcobalamin support

Pros

  • Lichen-derived vitamin D3
  • Methylcobalamin form
  • Useful vitamin C
  • Broad vitamin list

Cons

  • Low and unidentified folate
  • Vitamin K form is not disclosed
  • No meaningful calcium or magnesium
  • Four gummies add carbohydrates

Warnings

  • People using warfarin or another vitamin K-sensitive anticoagulant should keep vitamin K intake consistent and review the gummy with their prescriber.

Nutrient quality

67 High impact

Lichen-derived vitamin D3 and methylcobalamin are useful forms, but folate, vitamin K, and most other forms are unspecified. The vitamin amounts are generally conservative and avoid an obvious excess.

Ingredient transparency

77 High impact

Every listed nutrient has a specific amount. No proprietary blend hides any listed active dose; daily directions and a complete inactive-ingredient list are not supplied.

Customer satisfaction

68 High impact

The supplied rating is favorable, with substantial volume behind it. Detailed feedback themes are absent, leaving repeated complaints and purpose fit uncertain.

Value for money

56 Moderate impact

A few good forms provide some quality, but missing form detail and limited depth weaken the premium. The serving cost is moderate for a gummy but still high relative to nutrient depth.

Report analysis

Goals

General Health
General Health
Impact
High effect
B+ Goal FitD+ Strength of SupportC CoverageB- Formula Quality
Folate · 120 mcgVitamin B12 · 9.6 mcgVitamin D · 20 mcgVitamin K · 120 mcgSelenium · 25 mcgZinc · 1.5 mgVitamin C · 90 mg

The varied vitamin profile supports several basic functions linked to daily resilience, including antioxidant protection and energy metabolism. Familiar vitamins and minerals provide stronger evidence than a formula built around experimental wellness ingredients.

Nutritional depth is mixed because folate, zinc, manganese, and several B vitamins are supplied in modest amounts. Unspecified forms for vitamin K, folate, and most minerals add uncertainty, while the gummy base brings a notable carbohydrate load.

Study evidence
Folate Supportive 80 studies
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Zinc Supportive 60 studies
Bone Health
Bone Health
Impact
Moderate effect
C+ Goal FitC- Strength of SupportD+ CoverageD Formula Quality
Vitamin K · 120 mcgVitamin D · 20 mcgManganese · 0.2 mgZinc · 1.5 mgVitamin C · 90 mg

Vitamin D3 provides direct support for calcium absorption, and vitamin K may contribute to mineral handling. The lichen-derived D3 source is clearly identified.

No calcium or magnesium is included, and the vitamin K subtype is not disclosed. The broad gummy multivitamin contains many unrelated nutrients and carbohydrates, making it weak as targeted bone support.

Study evidence
Manganese Adverse 12 studies
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Zinc Supportive 33 studies
Anti-Aging
Anti-Aging
Impact
Moderate effect
C- Goal FitC- Strength of SupportC CoverageC- Formula Quality
Folate · 120 mcgVitamin B12 · 9.6 mcgVitamin K · 120 mcgVitamin D · 20 mcg

The broad vitamin mix supports basic antioxidant, bone, and methylation needs, but it lacks a strongly targeted healthy-aging active. Vitamin D3 and methylcobalamin are favorable choices, while the vitamin K and folate forms are not identified.

Many nutrients are supplied at modest amounts, so breadth comes at the expense of depth. The gummy format also adds carbohydrate without improving the formula's aging-specific contribution.

Study evidence
Folate Supportive 16 studies
Vitamin D Supportive 50 studies
Vitamin K Supportive 27 studies
Zinc Supportive 10 studies
Heart Health
Heart Health
Impact
Moderate effect
C Goal FitD- Strength of SupportC CoverageC+ Formula Quality
Vitamin K · 120 mcgVitamin B12 · 9.6 mcgVitamin B6 · 3.7 mgFolate · 120 mcgVitamin D · 20 mcg

B vitamins plus vitamins D and K create several plausible links to vascular and homocysteine support. The folate amount is modest, and the label does not identify the folate or vitamin K forms.

Methylcobalamin and vitamin D3 are useful form choices within the broader blend. The gummy is better suited to general nutrient coverage than focused cardiovascular support.

Study evidence
Folate Supportive 116 studies
Vitamin D Mixed 164 studies
Vitamin K Mixed 62 studies

Ingredients

IngredientAmount per serving
Calories
35 Calorie(s)
Total Carbohydrates
8 Gram(s)
Vitamin A
450 mcg
Vitamin C
90 mg
Vitamin D (Lichen, Vitamin D3)
 20 mcg
Vitamin E
11.5 mg
Vitamin K
120 mcg
Thiamin
0.6 mg
Riboflavin
0.6 mg
Niacin
8 mg
Vitamin B6
3.7 mg
Folate
120 mcg
Vitamin B12 (Methylcobalamin)
 9.6 mcg
Biotin
114 mcg
Pantothenic Acid
4 mg
Zinc
1.5 mg
Selenium
25 mcg
Manganese
0.2 mg
Chromium
35 mcg
Gluten Free Vegan Kosher Dairy Free Women 50+ Organic Women 18–50 Vegetarian
Report overview
Folate · 120 mcg OverallScore16
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The label does not identify the folate form, so its bioavailability cannot be judged. The listed amount is too low for strong folate support. Some vitamin B12 is included, but it does not meet the stated co-supplementation benchmark. Value is only moderate for the folate quality provided.

View ingredientView products
Vitamin K · 120 mcg OverallScore4
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The listed vitamin K amount could be useful, but the label does not reveal its form. An effective MK-7 dose therefore cannot be confirmed. The serving cost is moderate, yet the carbohydrate-based gummy and missing lipid carrier weaken its fit for targeted vitamin K2 use.

View ingredientView products
Loading alternative details
86 Performance

Methyl B-12 Methyl Folate Lonzenge Natural Cherry Flavor

Solaray
<p>Branded methylfolate and methylcobalamin provide stronger form quality than the gummy's unspecified folate and preserve B12 support. The lozenge omits vitamin K and the rest of the women's 40-plus nutrient profile, while the B12 amount favors targeted use.</p>
87 Performance

Vitamin D3 25 mcg (1000 IU) & K2 120 mcg

Natural Factors
<p>Moderate vitamin D3 and MK-7 create a clear, balanced D-and-K pairing compared with the gummy's unidentified vitamin K form. It is a focused formula rather than a complete women's 40-plus multivitamin, and vitamin K requires medication review with warfarin-type drugs.</p>
86 Performance

B-6 B-12 Folic Acid Drop Ins Natural Mixed Berry Flavor

KAL
<p>Active B6, methylfolate, and methylcobalamin improve B-vitamin form quality and make the active profile easy to assess. The concentrated B12 formula omits vitamin K and most of the women's 40-plus multivitamin nutrients, so it suits targeted use rather than full replacement.</p>
88 Budget

MegaFolinic 800 mcg

Source Naturals
<p>Active folinic acid replaces the gummy's unspecified folate with a clearly identified form at a much lower serving cost. It is a high-potency single nutrient rather than a women's 40-plus multivitamin and omits vitamin K, so total folate and vitamin B12 status still matter.</p>
88 Budget

Vitamin K2 MK-7 100 mcg

Nutricost
<p>MK-7 provides a specific, long-acting vitamin K2 form at far better serving value than the gummy. The capsule does not replace the women's 40-plus multivitamin's folate or wider nutrient coverage, and vitamin K can interfere with warfarin-type medicines.</p>
86 Budget

Liquid D-3 & MK-7

NOW
<p>Vitamin D3 and MK-7 provide clearly specified bone-related nutrients at a lower serving cost without the gummy's carbohydrate load. The liquid is not a full women's 40-plus multivitamin, and total vitamin D intake plus anticoagulant use require consideration.</p>
87 Value

Methyl Folate 800 mcg

KAL
<p>Active methylfolate supplies clearly identified folate with a long, economical supply and no gummy carbohydrate load. The amount is targeted and not paired with B12, while vitamin K and the rest of the women's 40-plus multivitamin remain absent.</p>
85 Value

Vitamin K2 MenaQ7 100 mcg

AN Amazing Nutrition Amazing Formulas
<p>Natto-derived MK-7 provides transparent vitamin K2 support with strong serving efficiency. It does not supply folate or broad women's 40-plus nutrition, and vitamin K can oppose warfarin-type medicines.</p>
86 Value

Vitamins D3 2500 IU (62.5 mcg) & K2 120 mcg

NaturesPlus
<p>MK-7 and vitamin D3 provide focused bone and cardiovascular nutrients at strong serving value without gummy carbohydrates. The tablet does not replace folate or the broader women's 40-plus formula, while vitamin D and anticoagulant use require individual review.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  2. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
    Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Meta-analysis6,759 participants19 studies pooledBone Health forVitamin K
  3. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  4. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  5. Association of vitamin K with cardiovascular events and all-cause mortality: a systematic review and meta-analysis.
    Chen HG; Sheng LT; Zhang YB; Cao AL; Lai YW; Kunutsor SK; Jiang L; Pan A · European journal of nutrition · 2020
    Meta-analysis222,592 participants21 studies pooledCardiovascular Support forVitamin K
  6. Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease.
    van den Heuvel EG; van Schoor NM; Lips P; Magdeleyns EJ; Deeg DJ; Vermeer C; den Heijer M · Maturitas · 2014
    Cohort study577 participantsCardiovascular Support forVitamin K
  7. One-carbon metabolism-related compounds are associated with epigenetic aging biomarkers: results from the cross-sectional National Health and Nutrition Examination Survey 1999-2002.
    Bozack AK; Khodasevich D; Nwanaji-Enwerem JC; Gladish N; Shen H; Daredia S; Gamble M; Needham BL; Rehkopf DH; Cardenas A · The American journal of clinical nutrition · 2025
    Cross-sectional study2,346 participantsAnti-Aging forFolate
  8. Longitudinal associations of one-carbon metabolism biomarkers with biological and epigenetic aging in older adults in India.
    Wang J; Crimmins E; Kim JK; Chang NS; Dey S; Lee J; Thyagarajan B; Vivek S · GeroScience · 2026
    Cohort studyAnti-Aging forFolate
  9. Associations between leukocyte telomere length and three measures of folate status: a cross-sectional analysis of NHANES 1999-2002.
    Xue Q; Chen H · Frontiers in nutrition · 2026
    Cross-sectional study7,324 participantsAnti-Aging forFolate
  10. Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging.
    Kado DM; Karlamangla AS; Huang MH; Troen A; Rowe JW; Selhub J; Seeman TE · The American journal of medicine · 2005
    Cohort study499 participantsAnti-Aging forFolate
  11. Blood folate is associated with asymptomatic or partially symptomatic Alzheimer's disease in the Nun study.
    Wang H; Odegaard A; Thyagarajan B; Hayes J; Cruz KS; Derosiers MF; Tyas SL; Gross MD · Journal of Alzheimer's disease : JAD · 2012
    Cohort study60 participantsAnti-Aging forFolate
  12. Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
    Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Cohort study389,217 participantsAnti-Aging forVitamin D
  13. Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
    Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Cohort study9,940 participantsAnti-Aging forVitamin D
  14. Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
    Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
    Cohort study1,292 participantsAnti-Aging forVitamin D
  15. Vitamin D deficit is associated with accelerated brain aging in the general population.
    Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
    Cross-sectional study1,865 participantsAnti-Aging forVitamin D
  16. Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
    Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Cohort study1,759 participantsAnti-Aging forVitamin D
  17. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  18. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  19. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  20. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  21. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  22. The Association between Dietary Nutrient Intake and Acceleration of Aging: Evidence from NHANES.
    Ma J; Li P; Jiang Y; Yang X; Luo Y; Tao L; Guo X; Gao B · Nutrients · 2024
    Cross-sectional study4,692 participantsAnti-Aging forZinc
  23. The immune system and the impact of zinc during aging.
    Haase H; Rink L · Immunity & ageing : I & A · 2010
    Narrative reviewAnti-Aging forZinc
  24. Associations between serum trace elements and biological age acceleration in the Chinese elderly: A community-based study investigating the mediating role of inflammatory markers and the moderating effect of physical activity.
    Wang Y; Zhu W; Zhang T; Liu Q; Zou M; Xie Y; Wang M; Wang TS; Pang Y; Jing T; Zhang R · Journal of hazardous materials · 2025
    Observational studyAnti-Aging forZinc
  25. Bidirectional associations of zinc supplement intake with biological ageing interacted by metabolic equivalent of task: A large-scale population-based Biobank study.
    Zhou Y; Zhou J; Li Z; Wang J; Li H; Yin X; Gao J; Wu Y; Li J; Sun YX; Li Y; Wang W; Eser PO; Assimes TL; He J; Chen G · Clinical nutrition (Edinburgh, Scotland) · 2025
    Cross-sectional study68,947 participantsAnti-Aging forZinc
  26. Zinc, metallothioneins, longevity: effect of zinc supplementation on antioxidant response: a Zincage study.
    Mocchegiani E; Zincage Consortium · Rejuvenation research · 2008
    Narrative reviewAnti-Aging forZinc
  27. Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
    Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
    Cross-sectional study2,640 participantsBone Health forManganese
  28. The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
    Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
    Narrative reviewBone Health forManganese
  29. Associations of multiple metals with bone mineral density: A population-based study in US adults.
    Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
    Cross-sectional studyBone Health forManganese
  30. Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
    Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
    Cross-sectional study31 participantsBone Health forManganese
  31. Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
    Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
    Cross-sectional study9,732 participantsBone Health forManganese
  32. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  33. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  34. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  35. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  36. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  37. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  38. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  39. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  40. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  41. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
    Elmståhl S; Gullberg B; Janzon L; Johnell O; Elmståhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
    Cohort study6,576 participantsBone Health forZinc
  42. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
    Randomized trial147 participantsBone Health forZinc
  43. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
    Randomized trial242 participantsBone Health forZinc
  44. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
    Randomized trial60 participantsBone Health forZinc
  45. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
    Meta-analysis40 studies pooledBone Health forZinc
  46. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  47. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  48. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  49. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  50. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  51. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  52. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  53. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  54. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  55. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  56. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  57. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  58. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  59. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  60. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  61. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  62. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  63. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  64. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  65. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  66. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  67. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  68. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  69. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  70. Folic Acid Therapy Reduces the First Stroke Risk Associated With Hypercholesterolemia Among Hypertensive Patients.
    Qin X; Li J; Spence JD; Zhang Y; Li Y; Wang X; Wang B; Sun N; Chen F; Guo J; Yin D; Sun L; Tang G; He M; Fu J; Cai Y; Shi X; Ye P; Chen H; Zhao S; Chen M; Gao C; Kong X; Hou FF; Huang Y; Huo Y · Stroke · 2017
    Randomized trial20,702 participantsHeart Health forFolate
  71. Periconception Red Blood Cell Folate and Offspring Congenital Heart Disease : Nested Case-Control and Mendelian Randomization Studies.
    Chen H; Zhang Y; Wang D; Chen X; Li M; Huang X; Jiang Y; Dou Y; Wang Y; Ma X; Sheng W; Jia B; Yan W; Huang G; SPCC (Shanghai Preconception Cohort) Group · Annals of internal medicine · 2022
    Case-control study985 participantsHeart Health forFolate
  72. Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies.
    Jayedi A; Zargar MS · Critical reviews in food science and nutrition · 2020
    Meta-analysis369,746 participants11 studies pooledHeart Health forFolate
  73. Folate Biomarkers, Folate Intake, and Risk of Death From All Causes, Cardiovascular Disease, and Cancer: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.
    Fallah M; Karim Dehnavi M; Lotfi K; Aminianfar A; Azadbakht L; Esmaillzadeh A · Nutrition reviews · 2025
    Meta-analysis423,304 participants25 studies pooledHeart Health forFolate
  74. The association between folic acid supplementation and congenital heart defects: Systematic review and meta-analysis.
    Wondemagegn AT; Afework M · SAGE open medicine · 2022
    Meta-analysis37 studies pooledHeart Health forFolate
  75. Vitamin D supplementation for cardiometabolic risk markers in pregnant women based on the gestational diabetes mellitus or obesity status : a randomized clinical trial.
    Yin WJ; Wang P; Ma SS; Tao RX; Hu HL; Jiang XM; Zhang Y; Tao FB; Zhu P · European journal of nutrition · 2024
    Randomized trial1,537 participantsHeart Health forVitamin D
  76. Paricalcitol and endothelial function in chronic kidney disease trial.
    Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
    Randomized trial88 participantsHeart Health forVitamin D
  77. Vitamin D Supplementation, Serum 25(OH)D Concentrations and Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis.
    Mirhosseini N; Rainsbury J; Kimball SM · Frontiers in cardiovascular medicine · 2020
    Meta-analysis81 studies pooledHeart Health forVitamin D
  78. Does vitamin D supplementation modulate metabolic risk factors of cardiovascular disease? A systematic review and meta-analysis of clinical trials.
    Abumweis S; Alqadi S; Al Tarteer A; Alrefai W; Alzoughool F; Jew S; Qudah T · Asia Pacific journal of clinical nutrition · 2026
    Meta-analysis45 studies pooledHeart Health forVitamin D
  79. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisHeart Health forVitamin D
  80. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsHeart Health forVitamin K
  81. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K
  82. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsHeart Health forVitamin K
  83. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsHeart Health forVitamin K