Product Image

Enzyme Nutrition Multi-Vitamin Two Daily

Enzymedica
4.6
★ ★ ★ ★ ★
(210 ratings)
Vitamin A 5000 IU
Vitamin E 50 IU
Iron 3 mg
Vitamin D 400 IU
Folate 400 mcg
Product Image
Score55
Broad vitamins and diverse natural vitamin E forms are useful, but shallow minerals and unquantified specialty blends limit transparency and value.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
General Health
Hair Health

Score 55

Broad vitamins and diverse natural vitamin E forms are useful, but shallow minerals and unquantified specialty blends limit transparency and value.
How scoring works
$22.49($0.74 per serving)
Vitacost
$ 31.99
iHerb
$ 22.49
Report prices

Analysis

Beta-carotene, vitamin D3, natural mixed tocopherols and tocotrienols, B vitamins, folate, and trace minerals create broad multivitamin coverage. The vitamin E profile is more diverse than a simple alpha-tocopherol-only product.

Calcium, magnesium, iron, selenium, copper, and several other minerals are present at small amounts. Vitamin B12 form is not given, while enzymes, probiotics, ATP, and botanical entries lack usable potency information.

Two capsules per serving are reasonable, but the premium cost is not matched by ingredient-level clarity. The product is best judged as a general multivitamin rather than as a meaningful enzyme or probiotic supplement.

Who is it for
  • Adults seeking broad daily vitamin coverage
  • People who value mixed tocopherols and tocotrienols
Best for
  • General multivitamin use
  • Vitamin E diversity
  • Two-capsule daily nutrition

Pros

  • Uses vitamin D3
  • Includes mixed natural tocopherols and tocotrienols
  • Broad B-vitamin profile
  • Beta-carotene vitamin A source

Cons

  • Most mineral amounts are low
  • Vitamin B12 form is unspecified
  • Enzyme and probiotic potency cannot be assessed
  • Weak value for the disclosure level

Warnings

  • Vitamin K content matters for people taking warfarin, who should keep intake consistent.
  • The unquantified enzyme and botanical entries limit screening for individual sensitivities.

Nutrient quality

68 High impact

Natural mixed vitamin E and vitamin D3 strengthen the broad multivitamin base. Zero-quantity specialty entries and lightly dosed minerals make the signature enzyme formula difficult to assess.

Ingredient transparency

42 Lower impact

Many vitamin and mineral amounts are stated. Zero-quantity enzyme, probiotic, and ATP entries plus a broad botanical listing prevent assessment of important advertised features.

Customer satisfaction

68 High impact

The supplied satisfaction metric is generally positive and response volume is substantial. Specific firsthand feedback was not supplied, so recurring complaints and purpose alignment remain uncertain.

Value for money

46 Lower impact

Natural vitamin E adds quality, but the high cost is not well supported by unquantified specialty ingredients. More focused or transparent alternatives are likely to offer better category value.

Report analysis

Goals

General Health
General Health
Impact
High effect
A- Goal FitD+ Strength of SupportB- CoverageD Formula Quality
Folate · 400 mcgVitamin B12 · 15 mcgVitamin D · 400 IUMagnesium · 5 mgVitamin K · 30 mcgSelenium · 25 mcgZinc · 7.5 mgVitamin C · 20 mg

A wide range of vitamins provides routine support for energy metabolism, antioxidant needs, and nutritional gaps. Several vitamin amounts are suitable for maintenance.

Most minerals are present only in small amounts, and important forms such as vitamin B12 are not identified. Unquantified enzyme, probiotic, and botanical blends weaken transparency and make the broader claims difficult to assess.

Hair Health
Hair Health
Impact
Moderate effect
C- Goal FitC- Strength of SupportC- CoverageC+ Formula Quality
Biotin · 150 mcgVitamin D · 400 IUZinc · 7.5 mgIron · 3 mgVitamin C · 20 mg

Biotin, zinc, selenium, vitamin D, vitamin E, vitamin A, low-dose iron, and B vitamins provide broad maintenance nutrition for hair. Most goal-relevant amounts are modest, so the formula is more likely to help basic dietary coverage than targeted shedding or thickness concerns.

Natural mixed tocopherols and tocotrienols are useful antioxidant forms. Low iron, zinc, selenium, vitamin C, and vitamin D and several unspecified mineral forms limit its effectiveness as a dedicated hair supplement.

Study evidence
Biotin Supportive 4 studies
Iron Disputed 25 studies
Selenium Disputed 7 studies
Vitamin A Disputed 13 studies
Vitamin C Mixed 5 studies
Vitamin D Disputed 34 studies
Vitamin E No effect 3 studies
Zinc Supportive 22 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene)
 5000 IU
Vitamin C (Citrus Concentrate)
 20 mg
Vitamin D3 (Cholecalciferol)
 400 IU
Vitamin E (Mixed Tocopherols, Natural, Mixed Tocotrienols, Natural)
 50 IU
Vitamin K (Alfalfa)
 30 mcg
Thiamine (Vitamin B1)
 3 mg
Riboflavin (Vitamin B2)
 3 mg
Niacin (Niacinamide, Vitamin B3)
 20 mg
Vitamin B2 (Lactobacillus bulgaricus)
 3 mg
Folate (Alfalfa)
 400 mcg
Vitamin B12
15 mcg
Biotin
150 mcg
Pantothenic Acid (Vitamin B5)
 10 mg
Calcium (Lactobacillus bulgaricus)
 5 mg
Iron (Lactobacillus bulgaricus)
 3 mg
Iodine
75 mcg
Magnesium (Lactobacillus bulgaricus)
 5 mg
Zinc
7.5 mg
Selenium (Lactobacillus bulgaricus)
 25 mcg
Copper (Lactobacillus bulgaricus)
 50 mcg
Manganese (Lactobacillus bulgaricus)
 1 mg
Chromium
25 mcg
Molybdenum
10 mcg
Serratiopeptidase
0 NP
Vanadium
5 mcg
Adenosine Triphosphate
0 NP
Nutrient Enhancing Enzyme Blend
0 NP
Superfoods & Botanicals
75 mg
Lactobacillus acidophilus DDS-1
0 NP
Gluten Free Adults 18–50 Dairy Free
Report overview
Vitamin A (Beta-Carotene) · 5000 IU OverallScore74
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value

The beta-carotene dose is well centered for routine vitamin A support, but its natural or synthetic source is not stated. The dry capsule contains no listed lipid carrier and may depend on food for effective absorption. Strong dose disclosure and a broad multivitamin profile partly balance its relatively high cost as a vitamin A source.

View ingredientView products
Vitamin E (Mixed Tocopherols, Natural, Mixed Tocotrienols, Natural) · 50 IU OverallScore69
D+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB- Value

Natural mixed tocopherols and mixed tocotrienols create a broad vitamin E profile. The combined amount reaches a useful general-support level, though the label does not identify individual isomers or a d-alpha prefix. The moderate serving cost offers fair value for the inclusion of tocotrienols.

View ingredientView products
Iron (Lactobacillus bulgaricus) · 3 mg OverallScore54
C- Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value

Fermented iron offers a specialized food-based source, while the vegetable capsule supports practical digestive tolerance. The iron amount is low, and zinc may compete with iron absorption. The serving cost is high, and two units modestly reduce convenience.

View ingredientView products
Loading alternative details
78 Performance

Children's Chewable

Thompson
Natural-form vitamin E, vitamin D3, beta-carotene, folate, and iron preserve the main multivitamin collections with fewer unverifiable specialty claims. Some minerals are lightly dosed, but the low serving cost and clearer amounts improve practicality.
74 Performance

Children's Chewable Multi-Vitamin & Mineral Supplement Natural Grape Flavor!

Natures Plus Source of Life Animal Parade
Methylfolate, methylcobalamin, vitamin D3, natural-form vitamin E, beta-carotene, and named mineral complexes improve nutrient-form quality. Light mineral doses remain, but the label is more useful than the original’s zero-amount enzyme and probiotic entries.
70 Performance

Mega-Kid Berry

Source Naturals
Vitamin D3, natural-form vitamin E, beta-carotene, folate, and iron provide broad overlap in a child-friendly chewable. Tiny botanical additions and bee-pollen allergy concerns are limitations, yet the core nutrient profile is easier to judge.
75 Budget

Flintstones Complete

Bayer
Broad children’s vitamin and mineral coverage comes at a much lower serving cost and avoids undosed enzyme, probiotic, and ATP entries. Several nutrient forms are still unspecified, so absorption quality cannot be compared fully.
75 Budget

Multi Adult Gummies

Nature Made
A low-cost gummy supplies broad vitamins, including vitamin D3, without the original’s unquantified specialty additions. It omits iron and many minerals, but the simpler formula offers clearer practical value.
71 Budget

Norwegian Cod Liver Oil 1000 mg Fresh Orange Flavor

AN Amazing Nutrition Amazing Omega
Vitamin D3, natural vitamin E, vitamin A, and cod liver oil provide a focused lower-cost option for several overlapping nutrients. It is not a complete multivitamin, and preformed vitamin A calls for care with other sources.
74 Value

Children's Multivitamin Gummies

Equate
A simple gummy supplies modest vitamin coverage at much better serving value. It sacrifices iron, mineral breadth, and named nutrient forms, but avoids charging for undosed specialty ingredients.
70 Value

Flintstones Gummies Complete

Bayer
Useful vitamin D and folate support basic daily coverage in a convenient, economical gummy. The formula lacks iron and has label ambiguity, but its value is easier to justify than unquantified enzyme and probiotic features.
67 Value

Multivitamin with Omega-3

Nature Made Kids First
Vitamin D3 and a child-focused vitamin profile offer practical daily coverage at a lower serving cost. Unquantified fish oil and less preferred vitamin forms limit quality, but the formula remains more economical than the original.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health forBiotin
  2. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health forBiotin
  3. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  4. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  5. The Association Between Alopecia Areata and Iron Deficiency Anemia: A Large-Scale Population-Based Case-Control Study.
    Davidovici B; Drutin Y; Ben-Tov A; Mimouni D; Wohl Y · Journal of personalized medicine · 2026
    Case-control study100,203 participantsHair Health forIron
  6. Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis.
    Treister-Goltzman Y; Yarza S; Peleg R · Skin appendage disorders · 2022
    Meta-analysis10,029 participants36 studies pooledHair Health forIron
  7. Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Versus Sleeve Gastrectomy.
    Chinisaz F; Maleki T; Najjari K; Miratashi Yazdi SA · Obesity surgery · 2026
    Cohort study261 participantsHair Health forIron
  8. Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium.
    Thamotharan N; Harikumar MV; Sundaram M; Swaminathan A; Rangarajan S · Cureus · 2026
    Cross-sectional study100 participantsHair Health forIron
  9. Diagnosis and treatment of female alopecia: Focusing on the iron deficiency-related alopecia.
    Lin CS; Chan LY; Wang JH; Chang CH · Tzu chi medical journal · 2023
    Cohort study155 participantsHair Health forIron
  10. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  11. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
    Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
    Observational study1,407 participantsHair Health forSelenium
  12. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
    Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
    Randomized trial64 participantsHair Health forSelenium
  13. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
    Meta-analysis764 participantsHair Health forSelenium
  14. Scientific opinion on the tolerable upper intake level for selenium.
    EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
    Systematic reviewHair Health forSelenium
  15. Topical tretinoin for hair growth promotion.
    Bazzano GS; Terezakis N; Galen W · Journal of the American Academy of Dermatology · 1986
    Non-randomized trial56 participantsHair Health forVitamin A
  16. A review of isotretinoin in the treatment of frontal fibrosing alopecia.
    Shahpar A; Nezhad NZ; Sahaf AS; Ahramiyanpour N · Journal of cosmetic dermatology · 2024
    Systematic review232 participants15 studies pooledHair Health forVitamin A
  17. Efficacy of Isotretinoin and Acitretin in Treatment of Frontal Fibrosing Alopecia: Retrospective Analysis of 54 Cases.
    Rakowska A; Gradzińska A; Olszewska M; Rudnicka L · Journal of drugs in dermatology : JDD · 2018
    Cohort study54 participantsHair Health forVitamin A
  18. Systemic Treatments for Lichen Planopilaris and Frontal Fibrosing Alopecia: A Retrospective Study of 315 Patients.
    Willaert M; Van Dongen T; Dikrama P; Nijsten T; Hijnen D; Waalboer-Spuij R · Acta dermato-venereologica · 2025
    Cohort study315 participantsHair Health forVitamin A
  19. Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes.
    Sharma A; Goren A; Dhurat R; Agrawal S; Sinclair R; Trüeb RM; Vañó-Galván S; Chen G; Tan Y; Kovacevic M; Situm M; McCoy J · Dermatologic therapy · 2020
    Single-arm trialHair Health forVitamin A
  20. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  21. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  22. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  23. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  24. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  25. Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis.
    Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Meta-analysis2,039 participants14 studies pooledHair Health forVitamin D
  26. Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
    Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
    Randomized trial60 participantsHair Health forVitamin D
  27. Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
    Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
    Meta-analysisHair Health forVitamin D
  28. Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
    El Taieb MA; Hegazy EM; Ibrahim HM; Osman AB; Abualhamd M · Archives of dermatological research · 2020
    Randomized trial60 participantsHair Health forVitamin D
  29. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
    Chen Y; Dong X; Wang Y; Li Y; Xiong L; Li L · Journal of cosmetic dermatology · 2024
    Meta-analysis10,670 participants23 studies pooledHair Health forVitamin D
  30. Effects of tocotrienol supplementation on hair growth in human volunteers.
    Beoy LA; Woei WJ; Hay YK · Tropical life sciences research · 2014
    Randomized trial38 participantsHair Health forVitamin E
  31. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
    Zhou L; Zhu W; Chen Y · Frontiers in nutrition · 2026
    Meta-analysis1,658 participants19 studies pooledHair Health forVitamin E
  32. Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss: A Systematic Review.
    Drake L; Reyes-Hadsall S; Martinez J; Heinrich C; Huang K; Mostaghimi A · JAMA dermatology · 2023
    Systematic review30 studies pooledHair Health forVitamin E
  33. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  34. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  35. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  36. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  37. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc