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Magnesium Citrate

4.8
★ ★ ★ ★ ★
(654 ratings)
Magnesium 400 mg
Product Image
Score85
Three complementary magnesium forms provide a substantial 400 mg serving. Higher cost, three softgels, and added fat limit practical value.
How scoring works
Softgel
Quantity:180 Softgel(s) • (60 servings)
Goals:
General Health
Stress Relief
Energy
Heart Health
Fitness
Bone Health
Cardiovascular Support
Digestive Health

Score 85

Three complementary magnesium forms provide a substantial 400 mg serving. Higher cost, three softgels, and added fat limit practical value.
How scoring works
$34.00($0.56 per serving)
Vitacost
$ 34.00
iHerb
$ 34.00
Pure Formulas
$ 34.00
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Analysis

Three softgels provide a stated 400 mg magnesium blend from citrate, glycinate, and malate. The combination balances moderate absorption from citrate with stronger tolerance and uptake potential from glycinate and malate.

The dose supports broad magnesium-dependent functions, including energy, muscle, nerve, and cardiovascular activity. No named chelation standard or supporting cofactor is disclosed, so the multi-form label is the main quality advantage.

Sixty servings offer a reasonable supply, but the serving cost is above the category midpoint. The softgel format adds 2 g fat and may be less convenient than a simpler two-capsule blend.

Who is it for
  • Adults comfortable with softgels
  • Users seeking broad magnesium support
  • People who can account for dietary and supplemental magnesium
Best for
  • Routine magnesium supplementation
  • Muscle, nerve, and energy support
  • Softgels dosing

Pros

  • Combines citrate, glycinate, and malate
  • Clearly states 400 mg magnesium
  • Sixty-serving supply
  • Strong overall absorption potential

Cons

  • Requires three softgels
  • Serving cost is above average
  • Adds 2 g fat per serving
  • No named chelation standard

Warnings

  • A 400 mg magnesium serving may cause diarrhea or abdominal discomfort
  • Kidney impairment can increase the risk of magnesium accumulation
  • Separate magnesium from tetracycline or quinolone antibiotics and bisphosphonates

Nutrient quality

93 Highest impact

The elemental magnesium amount is meaningful for supplementation. The amount is substantial and may challenge digestive tolerance.

Ingredient transparency

77 High impact

No broad blend hides the core amount, though complex naming reduces clarity. The serving count is supplied, but complete use directions are missing.

Customer satisfaction

91 Highest impact

The aggregate customer rating is strong. Specific experiences are absent, but the strong aggregate rating is broadly consistent with satisfaction.

Value for money

79 High impact

The price is supported mainly by useful core ingredients. The serving cost is high relative to the disclosed formula.

Report analysis

Goals

General Health
Impact
Highest effect
A Goal FitA Strength of SupportC+ CoverageA Formula Quality
Magnesium · 400 mg

Magnesium glycinate, malate, and citrate provide strong absorption potential for a foundational mineral. The substantial amount supports energy metabolism, nerve signaling, and muscle function.

The single-mineral design offers depth rather than broad wellness coverage. A full serving may loosen stools or cause digestive discomfort, particularly because citrate is included.

Study evidence
Magnesium Supportive 114 studies
Stress Relief
Impact
Highest effect
B+ Goal FitA+ Strength of SupportB- CoverageA+ Formula Quality
Magnesium · 400 mg

Magnesium supports nerve regulation and muscle relaxation, especially when status is low. The 400 mg amount is useful and combines citrate, glycinate, and malate rather than poorly absorbed oxide.

All forms are clear and provide a strong foundational mineral strategy. The formula lacks an adaptogen or calming amino acid, so coverage remains concentrated in one pathway.

Study evidence
Magnesium Supportive 13 studies
Energy
Impact
Highest effect
B+ Goal FitA Strength of SupportC CoverageA+ Formula Quality
Magnesium · 400 mg

Magnesium is essential for ATP-producing enzymes and can meaningfully support energy when intake or status is low. The substantial amount and use of citrate, glycinate, and malate provide strong dose and form quality.

The formula remains a focused deficiency-correction tool rather than a broad alertness or stamina blend. A full serving may cause loose stools, and people with impaired kidney function face greater risk from magnesium accumulation.

Study evidence
Magnesium Supportive 4 studies
Heart Health
Impact
Highest effect
B+ Goal FitA- Strength of SupportB- CoverageA- Formula Quality
Magnesium · 400 mg

The 400 mg magnesium amount provides focused mineral support for vascular relaxation and cardiac electrical signaling. Human evidence is relevant, especially when magnesium intake or status is low.

Citrate, glycinate, and malate forms are all disclosed, though the label presentation makes their individual contribution unclear. The full amount may loosen stools, particularly because magnesium citrate is included.

Study evidence
Magnesium Supportive 158 studies
Fitness
Impact
High effect
C+ Goal FitA Strength of SupportC- CoverageA Formula Quality
Magnesium · 400 mg

The blend provides a substantial 400 mg magnesium amount in citrate, glycinate, and malate forms for muscle and energy support. Its benefit is most likely when magnesium intake is inadequate or exercise losses are high.

Multiple well-known forms and a fully disclosed total make the formula easy to assess. It remains a focused mineral product, so it does not directly cover power, endurance, hydration, or muscle repair.

Study evidence
Magnesium Disputed 29 studies
Bone Health
Impact
High effect
B- Goal FitA Strength of SupportD+ CoverageB Formula Quality
Magnesium · 400 mg

Magnesium citrate, glycinate, and malate provide substantial support for skeletal mineral structure and vitamin D metabolism. These forms are favorable, though the label does not clarify how the total is divided among them.

The formula has strong single-mineral depth but no calcium, vitamin D, vitamin K, or matrix-building nutrients. A 400 mg supplemental amount may cause diarrhea or cramping, especially in sensitive users, and impaired kidney function can increase magnesium accumulation risk.

Study evidence
Magnesium Supportive 48 studies

Ingredients

IngredientAmount per serving
Calories
20 Calorie(s)
Total Fat
2 Gram(s)
Magnesium (Magnesium Citrate, Magnesium Glycinate, Magnesium Malate)
400 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyD+ Value
+1

Glycinate and malate give the magnesium blend strong absorption potential alongside citrate. The 400 mg elemental amount is well aligned with the therapeutic range. The dose is well targeted, while an above-median serving cost and generic sourcing limit value.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  2. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  3. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  4. Magnesium Levels in Drinking Water and Coronary Heart Disease Mortality Risk: A Meta-Analysis.
    Jiang L; He P; Chen J; Liu Y; Liu D; Qin G; Tan N · Nutrients · 2016
    Meta-analysis77,821 participants10 studies pooledHeart Health forMagnesium
  5. Effects of Magnesium Citrate, Magnesium Oxide, and Magnesium Sulfate Supplementation on Arterial Stiffness: A Randomized, Double-Blind, Placebo-Controlled Intervention Trial.
    Schutten JC; Joris PJ; Groendijk I; Eelderink C; Groothof D; van der Veen Y; Westerhuis R; Goorman F; Danel RM; de Borst MH; Bakker SJL · Journal of the American Heart Association · 2022
    Randomized trial164 participantsHeart Health forMagnesium
  6. Low serum magnesium and cardiovascular mortality in chronic heart failure: a propensity-matched study.
    Adamopoulos C; Pitt B; Sui X; Love TE; Zannad F; Ahmed A · International journal of cardiology · 2009
    Cohort study1,569 participantsHeart Health forMagnesium
  7. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  8. Effects of long-term magnesium supplementation on endothelial function and cardiometabolic risk markers: A randomized controlled trial in overweight/obese adults.
    Joris PJ; Plat J; Bakker SJ; Mensink RP · Scientific reports · 2018
    Randomized trial52 participantsCardiovascular Support forMagnesium
  9. Serum magnesium and outcomes in heart failure with reduced ejection fraction: the GALACTIC-HF trial.
    Chimura M; Docherty KF; Jhund PS; Yang M; Ono R; Henderson AD; Metra M; Liu G; Divanji PH; Heitner SB; Kupfer S; Malik FI; Felker GM; Solomon SD; Teerlink JR; McMurray JJV · European heart journal · 2026
    Randomized trial6,147 participantsCardiovascular Support forMagnesium
  10. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  11. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  12. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  13. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  14. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  15. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  16. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  17. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  18. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  19. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  20. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  21. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  22. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  23. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  24. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy Fitness forMagnesium
  25. Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort.
    Welch AA; Skinner J; Hickson M · Nutrients · 2018
    Cross-sectional study156,575 participantsFitness forMagnesium
  26. Dietary Magnesium Is Positively Associated With Skeletal Muscle Power and Indices of Muscle Mass and May Attenuate the Association Between Circulating C-Reactive Protein and Muscle Mass in Women.
    Welch AA; Kelaiditi E; Jennings A; Steves CJ; Spector TD; MacGregor A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
    Cross-sectional study2,570 participantsFitness forMagnesium
  27. Nutritional intake as a determinant of high-speed resistance and multicomponent training efficacy on strength in older women at risk of sarcopenia. A randomized clinical trial.
    Polo-Ferrero L; Recio-Rodriguez JI; González-Manzano S; Martín-Vallejo J; Barbero-Iglesias FJ; Montero-Errasquín B; Cruz-Jentoft AJ; Méndez-Sánchez R · Clinical nutrition (Edinburgh, Scotland) · 2025
    Randomized trial80 participantsFitness forMagnesium
  28. Minerals and Sarcopenia in Older Adults: An Updated Systematic Review.
    van Dronkelaar C; Fultinga M; Hummel M; Kruizenga H; Weijs PJM; Tieland M · Journal of the American Medical Directors Association · 2023
    Systematic review45 studies pooledFitness forMagnesium
  29. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  30. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  31. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  32. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  33. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  34. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  35. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  36. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  37. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  38. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  39. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  40. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  41. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  42. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  43. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  44. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  45. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  46. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium