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K2 100 mcg

4.8
★ ★ ★ ★ ★
(1422 ratings)
Vitamin K 100 mcg
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Score83
Best suited to adults seeking a simple once-daily K2 softgel; the MK-7 source and oil carrier are not identified, and the serving value is weaker than larger-count alternatives.
How scoring works
Softgel
Quantity:30 Softgel(s) • (30 servings)
Goals:
Heart Health
General Health
Bone Health
Anti-Aging
Cardiovascular Support

Score 83

Best suited to adults seeking a simple once-daily K2 softgel; the MK-7 source and oil carrier are not identified, and the serving value is weaker than larger-count alternatives.
How scoring works
$19.49($0.64 per serving)
iHerb
$ 19.49
iHerb
$ 19.49
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Analysis

100 mcg of long-acting MK-7 in a softgel provides focused vitamin K2 support at a practical daily amount. The label provides enough detail to judge the central vitamin strategy.

The MK-7 source and oil carrier are not identified, and the serving value is weaker than larger-count alternatives. Format, dose, and companion nutrients determine whether it is appropriate for daily use.

The best fit is adults seeking a simple once-daily K2 softgel. Vitamin K and vitamin D support normal physiology, but the practical benefit depends on baseline intake and individual need.

Who is it for
  • Adults seeking a simple once-daily K2 softgel
  • Adults whose current vitamin intake matches the listed potency
  • Users able to account for vitamin K medication interactions
Best for
  • Long-acting MK-7 form
  • Useful daily amount
  • Users who accept that only thirty servings

Pros

  • Long-acting MK-7 form
  • Useful daily amount
  • Softgel delivery suits a fat-soluble vitamin
  • Focused single-ingredient design

Cons

  • Only thirty servings
  • MK-7 source is not identified
  • Oil carrier is not disclosed
  • Higher serving cost than larger bottles

Warnings

  • The 100 mcg vitamin K serving can counteract warfarin and related vitamin K antagonist anticoagulants.
  • Bile-acid sequestrants and orlistat can reduce absorption of fat-soluble vitamin K, which may make this softgel less reliable.
  • People with fat-malabsorption conditions may not absorb the listed vitamin K consistently and should use an individualized plan.

Nutrient quality

96 Highest impact

MK-7 is a long-acting vitamin K2 form, and the softgel suits a fat-soluble nutrient, and the 100 mcg MK-7 amount is meaningful for daily vitamin K2 support. The vitamin K2 amount is not obviously excessive for general supplementation, while the single active is tightly focused on vitamin K2 support without mismatched additions.

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Ingredient transparency

84 Highest impact

Every listed active ingredient has a specific amount, and no proprietary blend hides the dose of a listed active ingredient. Serving count is supplied, but complete daily-use directions are not provided, while inactive ingredients and excipients are not included in the supplied label details.

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Customer satisfaction

74 High impact

The supplied average rating is strong, and substantial review volume gives the average rating useful credibility. Specific review themes are unavailable, so repeated negatives and real-world fit remain uncertain.

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Value for money

72 High impact

The ingredient forms and dosing generally justify the product positioning, and the high serving cost weakens value relative to simpler alternatives. The focused active profile is not inflated by low-value additions, while the product is reasonably competitive but lacks a clear quality or value advantage.

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Goals

Heart Health
Impact
Highest effect
B+ Goal FitA+ Strength of SupportC- CoverageA+ Formula Quality
Vitamin K · 100 mcg

Vitamin K2 as MK-7 provides targeted support for vascular calcium management. The 100 mcg amount is fully disclosed and well aligned with common daily use.

The single-ingredient design offers strong depth in one pathway but no lipid, blood-pressure, or cardiac-energy support. Vitamin K can oppose warfarin-type anticoagulants, so intake should remain consistent under prescriber guidance.

Study evidence
Vitamin K Mixed 62 studies
General Health
Impact
Highest effect
B+ Goal FitA+ Strength of SupportC- CoverageA Formula Quality
Vitamin K · 100 mcg

MK-7 provides targeted support for proteins that guide normal calcium use in bone and vascular tissues. The clearly stated amount and long-lasting subtype provide strong depth for that specific role.

The streamlined formula is useful for focused vitamin K support but does not cover broader energy, immune, or nutrient needs. MK-7 can reduce the effect of warfarin-type anticoagulants, so people using those medicines need consistent intake planned with their prescriber.

Study evidence
Vitamin K Supportive 34 studies
Bone Health
Impact
Highest effect
B+ Goal FitA- Strength of SupportC- CoverageA Formula Quality
Vitamin K · 100 mcg

MK-7 directly supports activation of bone proteins that bind calcium into the matrix. Human evidence supports its role in vitamin K status and bone metabolism, although a stand-alone effect on fracture risk is less certain.

The 100 mcg amount is clearly disclosed and sits within a clinically used range. The softgel is practical, but its lipid carrier, branded source, and all-trans purity are not identified.

Study evidence
Vitamin K Supportive 78 studies
Anti-Aging
Impact
High effect
B Goal FitA- Strength of SupportC- CoverageA Formula Quality
Vitamin K · 100 mcg

MK-7 supports proteins involved in bone maintenance and vascular calcium control, giving it a meaningful healthy-aging role. The single-softgel serving provides a practical amount in a focused formula.

The active form and quantity are clear, while source, isomer purity, and carrier-oil details are absent. MK-7 can counteract warfarin, so users of that anticoagulant need consistent intake and clinician-guided monitoring.

Study evidence
Vitamin K Supportive 27 studies
Cardiovascular Support
Impact
High effect
B+ Goal FitA- Strength of SupportD+ CoverageA Formula Quality
Vitamin K · 100 mcg

MK-7 supports vascular calcium regulation through vitamin K-dependent proteins. The 100 mcg amount is suitable for daily targeted use and is fully stated.

Generic sourcing and an unnamed softgel carrier leave purity and absorption details uncertain. MK-7 can interfere with stable warfarin dosing, so people using warfarin-type anticoagulants need consistent intake and prescriber guidance.

Study evidence
Vitamin K Supportive 40 studies

Ingredients

IngredientAmount per serving
Vitamin K2 (Menaquinone-7)
100 mcg
Adults 18–50
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The 100 mcg MK-7 dose is well aligned with effective vitamin K2 use. Generic sourcing and an unspecified softgel carrier leave some quality details unresolved. Its serving cost remains within a reasonable range for a full dose.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  2. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  3. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  4. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  5. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  6. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  7. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  8. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  9. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  10. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  11. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  12. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  13. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  14. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  15. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  16. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  17. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  18. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  19. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  20. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K