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B-Complex with Metafolin L-5-MTHF

Douglas Laboratories
4.4
★ ★ ★ ★ ★
(44 ratings)
Vitamin B12 400 mcg
Riboflavin 12.7 mg
Vitamin B6 16.7 mg
Niacin 108 mg
Vitamin B5 100 mg
Biotin 400 mcg
Thiamin 100 mg
Product Image
Score 85

An advanced B-complex with key active forms like Metafolin, methylcobalamin, P-5-P, and Riboflavin 5-Phosphate, providing high-potency support for energy, cognition, and metabolism.

scaleQuantity:60 Capsule(s) • (60 servings)
track_changesGoals:
flag Brain Health
flag Cognitive Support
flag Energy
flag General Health
flag Mental Focus
flag Metabolism Boost
flag Cardiovascular Support
flag Heart Health

leaderboard Score 85

An advanced B-complex with key active forms like Metafolin, methylcobalamin, P-5-P, and Riboflavin 5-Phosphate, providing high-potency support for energy, cognition, and metabolism.

insightsAnalysis

Douglas Laboratories B-Complex with Metafolin L-5-MTHF offers a sophisticated blend of B vitamins, with a strong emphasis on providing nutrients in their active, readily usable forms. It notably features Metafolin, a preferred active form of folate, along with methylcobalamin for Vitamin B12, pyridoxal 5-phosphate (P-5-P) for Vitamin B6, and Riboflavin 5-Phosphate for Riboflavin. This is particularly beneficial for those with genetic variations affecting nutrient conversion.

The product delivers high doses of most B vitamins, ensuring comprehensive support for energy production, nervous system health, and DNA synthesis. It also includes Inositol Hexanicotinate, a non-flushing form of Niacin, which contributes to cardiovascular health without discomfort. While some traditional B forms are still present, the overall focus is on activated nutrients.

This B-complex is an excellent choice for individuals who require or prefer advanced, highly bioavailable forms of B vitamins. Its high potency and specific ingredient choices make it a premium option for targeted nutritional support.

thumb_upPros
  • Contains active forms of critical B vitamins (Metafolin, Methylcobalamin, P-5-P, Riboflavin 5-Phosphate).
  • High doses of most B vitamins for robust physiological support.
  • Uses Inositol Hexanicotinate for Niacin, a non-flushing form.
  • Excellent for individuals with genetic variations affecting B vitamin metabolism.
thumb_downCons
  • Some B vitamins are still present in non-active forms (Thiamine Hydrochloride, Pyridoxine Hydrochloride alongside P-5-P).
  • High combined Niacin dose (216mg) might be higher than some individuals need.
  • Lower review count compared to more established mass-market brands.
warningWarnings
  • The very high combined dose of Niacin (216mg), even with non-flushing forms, should be considered; consult a healthcare professional for individual suitability.
  • Individuals with specific health conditions or taking medications should consult a professional before use due to the high potency.
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$28.00($0.46 per serving)
Pure Formulas
$ 28.00
Vitacost
$ 28.00
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track_changesGoals
flagEnergy
Impact
Highest effect
With a high concentration of active B vitamin forms, this complex is highly effective at supporting cellular energy production. It provides superior cofactors for optimizing the conversion of nutrients into usable energy.
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flagMetabolism Boost
Impact
Highest effect
The advanced, active forms of B vitamins are directly involved in optimizing nutrient metabolism. This formula is designed to significantly enhance metabolic efficiency across a wide range of pathways.
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flagCognitive Support
Impact
Highest effect
Active B vitamins (Metafolin, Methylcobalamin, P-5-P) are crucial for neurotransmitter synthesis and nerve cell health. This directly supports cognitive processes like memory, learning, and mental clarity.
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flagBrain Health
Impact
Highest effect
The comprehensive profile of active B vitamins provides robust support for overall brain health, neuronal integrity, and neurological function, especially important for homocysteine metabolism and myelin sheath maintenance.
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flagMental Focus
Impact
Highest effect
By optimizing brain energy metabolism and supporting balanced neurotransmitter production through active B vitamins, this complex can significantly contribute to improved mental clarity and sustained focus.
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flagGeneral Health
Impact
Highest effect
This is an outstanding choice for comprehensive general health support, providing essential coenzyme forms of B vitamins. It offers broad-spectrum benefits for daily well-being and cellular function.
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flagMood Support
Impact
Highest effect
Active forms of folate, B6, and B12 are essential for the synthesis of mood-regulating neurotransmitters like serotonin and dopamine. This product provides strong support for maintaining emotional balance.
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flagStress Relief
Impact
Highest effect
B vitamins are vital for adrenal function and a healthy stress response. The high potency and active forms in this complex provide significant support to the nervous system, helping the body manage stress more effectively.
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scienceIngredients
IngredientAmount per serving
Thiamine
100 mg
Riboflavin
12.7 mg
Niacin
108 mg
Vitamin B6
16.7 mg
Folate
667 mcg DFE
Vitamin B12
400 mcg
Biotin
400 mcg
Pantothenic Acid
100 mg
grain_off Gluten Free person Adults 18–50
flagReport overview
Vitamin B12 90
This product features 400mcg of Methylcobalamin, the active and highly bioavailable form of Vitamin B12. This is an excellent choice for direct cellular utilization and optimal neurological support.
scienceView ingredientinventory_2View products
Vitamin B6 85
This product contains a total of 33.4mg of Vitamin B6, incorporating both the active Pyridoxal 5-Phosphate (P-5-P) and Pyridoxine Hydrochloride. The inclusion of the active form is highly beneficial for bioavailability.
scienceView ingredientinventory_2View products
Riboflavin 85
It delivers a total of 25.4mg of Riboflavin, combining its basic form with the active coenzyme form, Riboflavin 5-Phosphate. This dual approach ensures optimal utilization for energy production and cellular processes.
scienceView ingredientinventory_2View products
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