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L-Tryptophan 1000 mg

4.6
★ ★ ★ ★ ★
(231 ratings)
Vitamin B6 44 mg
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Score72
A clear high-dose tryptophan formula with supporting B6, but medication interactions and weak B6 value matter.
How scoring works
Tablet
Quantity:90 Tablet(s) • (45 servings)
Goals:

Score 72

A clear high-dose tryptophan formula with supporting B6, but medication interactions and weak B6 value matter.
How scoring works
$36.73($0.81 per serving)
Vitacost
$ 36.73
iHerb
$ 36.73
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Analysis

The serving combines two grams of L-tryptophan with 44 mg of pyridoxine hydrochloride. Tryptophan clearly dominates the formula, while B6 serves as a metabolic cofactor.

Pyridoxine is less direct than active P-5-P, and no riboflavin is listed to support conversion. The substantial tryptophan amount can add to serotonergic effects from several antidepressant classes.

The focused two-ingredient design is easy to assess, but it is expensive if the goal is vitamin B6. It best fits adults considering tryptophan who have already reviewed medication interactions.

Who is it for
  • Adults specifically seeking L-tryptophan
  • Users without serotonergic medication conflicts
  • People wanting B6 as a supporting cofactor
Best for
  • Targeted tryptophan intake
  • Two-ingredient simplicity
  • Evening amino-acid supplementation

Pros

  • Substantial tryptophan amount
  • Clearly quantified actives
  • Focused formula

Cons

  • Uses precursor-form B6
  • High cost for B6 alone
  • No riboflavin cofactor

Warnings

  • Do not combine L-tryptophan with SSRIs, SNRIs, or MAO inhibitors without prescriber approval
  • Tryptophan may cause drowsiness and should not be taken before driving
  • Long-term 44 mg B6 use should not be stacked with other high-B6 products

Nutrient quality

78 High impact

A substantial tryptophan amount and supporting vitamin B6 create a coherent formula. High B6 and sedating tryptophan reduce suitability for casual routine use.

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Ingredient transparency

76 High impact

All listed active amounts are clear and no proprietary blend hides a dose. Inactive ingredients and complete daily-use directions are not supplied.

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Customer satisfaction

65 High impact

The supplied aggregate rating is strong. The review count provides useful but not extensive rating evidence.

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Value for money

65 Moderate impact

A substantial tryptophan amount provides real formula value. The high serving cost and basic B6 form keep value only fair.

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Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride)
 44 mg
L-Tryptophan
2 Gram(s)
Gluten Free Adults 18–50 Dairy Free
Report overview
Vitamin B6 (Pyridoxine Hydrochloride) · 44 mg OverallScore62
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The vitamin amount falls in the preferred range, but it uses pyridoxine hydrochloride rather than the active P-5-P form. The single-tablet serving is practical and clearly states the B6 form. Value for B6 is weak because the serving cost is high for the synthetic form.

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89 Performance

P-5-P 50 mg

Country Life
<p>Active pyridoxal phosphate provides a meaningful B6 serving in a focused format. Compared with the original, the active B6 form avoids a conversion step, although the supplied dose may still exceed ordinary nutritional needs.</p>
89 Performance

BioCoenzymated Pyridoxal 5'-Phosphate 50 mg

Natural Factors
<p>Active pyridoxal phosphate provides a meaningful B6 serving in a focused format. Compared with the original, the active B6 form avoids a conversion step, although the supplied dose may still exceed ordinary nutritional needs.</p>
89 Performance

P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength

Swanson
<p>Active pyridoxal phosphate provides a meaningful B6 serving in a focused format. Compared with the original, the active B6 form avoids a conversion step, although the supplied dose may still exceed ordinary nutritional needs.</p>
80 Budget

B6 100 mg

Spring Valley
<p>Pyridoxine hydrochloride provides a clearly stated but very high B6 serving. Its lower serving cost improves affordability versus the original, although the supplied safety and form limitations still matter for long-term use.</p>
80 Budget

B-6 100 mg

21st Century
<p>Pyridoxine hydrochloride provides a clearly stated but very high B6 serving. Its lower serving cost improves affordability versus the original, although the supplied safety and form limitations still matter for long-term use.</p>
80 Budget

B-6 100 mg

NOW
<p>Pyridoxine hydrochloride provides a clearly stated but very high B6 serving. Its lower serving cost improves affordability versus the original, although the supplied safety and form limitations still matter for long-term use.</p>
87 Value

Vitamin B-6 50 mg

Nature's Way
<p>A mixed active and precursor B6 blend provides a meaningful B6 serving in a focused format. It combines retaining an active or partly active B6 form with a lower serving cost, although the dose and long-term-use cautions remain important.</p>
84 Value

P-5-P 50 mg

Nutricost
<p>Active P-5-P provides ready-to-use vitamin B6 in a simple high-potency capsule. It combines retaining an active or partly active B6 form with a lower serving cost, although the dose and long-term-use cautions remain important.</p>
85 Value

Vitamin B6 25 mg

Solgar
<p>Pyridoxine hydrochloride provides a meaningful B6 serving in a focused format. It combines keeping the ingredient panel focused and clearly stated with a lower serving cost, although the dose and long-term-use cautions remain important.</p>
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