B-6 100 mg
NOW
B-6 100 mg
4.8
★ ★ ★ ★ ★
(6041 ratings)
Vitamin B6 100 mg
Score 85.0
An affordable and widely popular Vitamin B6 supplement (pyridoxine HCl) from a reputable brand, offering a high dose for general health and metabolic support.
Quantity: 100 Capsule(s)Servings size: 1 Capsule(s) (100 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
leaderboard Score 85.0
An affordable and widely popular Vitamin B6 supplement (pyridoxine HCl) from a reputable brand, offering a high dose for general health and metabolic support.
insights Analysis
The NOW B-6 100 mg product provides Vitamin B6 in the common pyridoxine hydrochloride form, at a potent dose of 100mg. This dosage significantly exceeds the recommended daily allowance, aiming for therapeutic effects to support various metabolic functions. NOW is a well-established brand known for its quality testing and commitment to natural ingredients, which is generally reflected positively in online reviews. The product's high review count (5580) indicates widespread popularity and consumer satisfaction. Nutritionists acknowledge pyridoxine HCl as an effective form of B6, though many also highlight the benefits of the active P-5-P form for enhanced bioavailability, particularly for individuals with genetic variations affecting B6 metabolism.
- Highly affordable with a very low price per serving.
- Comes from NOW, a trusted brand known for quality and value.
- Large serving count provides a long-lasting supply.
- High review count reflects widespread consumer satisfaction.
- Uses Pyridoxine Hydrochloride (HCl) form, which may be less bioavailable than P-5-P for some individuals.
- The 100mg dose is high and might be excessive for some users, potentially requiring consultation with a healthcare professional.
$5.09($0.05 per serving)
 Vitacost | $ 5.09 | |
 Daily Vita | $ 5.20 | |
 Pure Formulas | $ 5.35 | |
 iHerb | $ 5.50 | |
 Amazon | $ 7.49 |
bolt Effectiveness for goals
Yes, Vitamin B6 is a widely recognized and often recommended treatment for nausea and vomiting in pregnancy, commonly known as morning sickness. It is considered a first-line pharmacological therapy for mild to moderate symptoms. Pregnant individuals should consult their healthcare provider before taking any supplements.
Vitamin B6, or pyridoxine, is crucial for over 100 enzyme reactions, primarily involved in protein metabolism, red blood cell formation, and nervous system health. It plays a key role in metabolic processes that convert food into energy. Maintaining adequate B6 levels supports overall health and proper bodily functions.
Absolutely, Vitamin B6 is vital for brain development and function, and for maintaining a healthy nervous system. It is involved in the synthesis of several key neurotransmitters, such as serotonin, dopamine, and GABA, which regulate mood, sleep, and cognitive processes. Adequate B6 intake is essential for proper nerve signaling.
Some studies suggest that Vitamin B6 supplementation may help reduce certain PMS symptoms, particularly mood swings, irritability, and breast tenderness. The exact mechanism is not fully understood, but it may involve its role in neurotransmitter synthesis. However, evidence is mixed, and more robust research is needed.
Vitamin B6 is involved in the production of neurotransmitters like serotonin and norepinephrine, which are critical for mood regulation. Some research indicates that B6 supplementation may positively influence mood and reduce symptoms of depression, particularly in individuals with a deficiency. However, it should not replace prescribed treatments for mental health conditions.
schedule Dosage, timing & forms
The Recommended Dietary Allowance (RDA) for adult men and women (19-50 years) is 1.3 mg per day. For those over 50, it is 1.7 mg for men and 1.5 mg for women. These recommendations are for healthy individuals.
Yes, taking excessively high doses of Vitamin B6, particularly from supplements, can be harmful. The most well-known adverse effect is sensory neuropathy, which can cause numbness and tingling in the extremities. This risk increases with doses significantly above the Tolerable Upper Intake Level (UL) of 100 mg/day.
The Tolerable Upper Intake Level (UL) for Vitamin B6 in adults is 100 mg per day. Consuming amounts significantly above this UL, particularly from supplements, can lead to adverse effects like peripheral neuropathy. It is advisable not to exceed this limit without professional guidance.
There is no specific "best" time to take Vitamin B6; it can be taken at any time of day. Consistency in taking the supplement is generally more important than the exact timing. Some individuals may prefer to take it with a meal to avoid potential stomach upset.
Vitamin B6 supplements commonly contain pyridoxine hydrochloride (pyridoxine HCl). The active coenzyme form, pyridoxal 5'-phosphate (P5P), is also available in some supplements. Other forms like pyridoxal and pyridoxamine also exist in food.
health_and_safety Safety & interactions
Long-term intake of high doses, typically exceeding 200 mg per day, can lead to sensory peripheral neuropathy, characterized by numbness, tingling, and pain in the extremities. Other less common side effects might include skin lesions, photosensitivity, and gastrointestinal issues. These effects usually resolve after discontinuing supplementation.
For adults, the tolerable upper intake level (UL) for Vitamin B6 is set at 100 mg per day from supplements and fortified foods. Consuming amounts above this UL regularly increases the risk of adverse effects, primarily neurological damage. This limit is established to prevent potential harm.
The primary and most concerning symptom of Vitamin B6 toxicity, typically from chronic high doses, is sensory peripheral neuropathy. This involves symptoms like numbness, tingling, and burning pain, often starting in the hands and feet. Other less common signs might include skin lesions or gastrointestinal upset.
Yes, Vitamin B6 can interact with several medications. For instance, it may reduce the effectiveness of levodopa (used for Parkinson's disease) and can interact with anti-seizure medications like phenytoin and phenobarbital. It is important to consult a healthcare provider when combining Vitamin B6 supplements with prescription drugs.
Vitamin B6 is generally considered safe during pregnancy and breastfeeding when taken within recommended dietary allowances. Higher doses might be used under medical supervision for specific conditions like severe morning sickness. Always discuss any supplementation with a healthcare provider to ensure appropriate dosing.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B6 | 100 mg |
Categories
Vitamin B6 85.0
As a standalone Vitamin B6 supplement, it provides a substantial dose and excellent value. While it uses the more common HCl form rather than the active P-5-P, it remains a highly effective and popular choice for addressing B6 needs.
Goals
Energy 80.0
Vitamin B6 is crucial for the metabolism of carbohydrates, fats, and proteins into energy, and this 100mg dose supports cellular energy production pathways effectively. Users often report improved energy levels, especially if deficient, as B6 aids in nutrient conversion.
General Health 80.0
This dosage supports various essential bodily functions, including red blood cell formation, immune system function, and the regulation of homocysteine levels, which is important for cardiovascular health. It serves as a foundational nutrient for overall metabolic processes and systemic well-being.
Brain Health 75.0
As a cofactor in the synthesis of important neurotransmitters like serotonin and dopamine, B6 plays a significant role in cognitive function and nerve signal transmission. While beneficial, the pyridoxine HCl form might not be as readily utilized by some individuals for direct brain health support compared to the active P-5-P form.
Recommended Alternatives
82 Value 
B-50
NOW
4.7
★★★★★
(30076 ratings)
This NOW B-50 Complex provides a balanced dose of 50mg B6 along with other essential B vitamins, offering more comprehensive support for overall metabolic health from a trusted brand at a reasonable price.
85 Value 
B-50 Complex
21st Century
4.7
★★★★★
(8446 ratings)
The 21st Century B-50 Complex offers 50mg of B6 as part of a comprehensive B vitamin blend, delivering excellent value for a full spectrum B-complex, especially for budget-conscious consumers seeking broader benefits.
80 Value 
B-50 Complex 50 mg
Source Naturals
4.7
★★★★★
(2521 ratings)
Source Naturals' B-50 Complex provides 50mg of B6 and other B vitamins, representing good value for a reputable brand's comprehensive B-complex, addressing various metabolic needs.
95 Performance 
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
4.8
★★★★★
(1062 ratings)
This Swanson product offers Vitamin B6 in its active P-5-P form, which is more bioavailable and often preferred by nutritionists, potentially providing more direct and efficient benefits for individuals seeking superior absorption.
90 Performance 
Vitamin B-6 50 mg
Nature's Way
4.8
★★★★★
(1720 ratings)
Nature's Way provides a 50mg P-5-P supplement, which is a highly bioavailable form of B6, making it a better choice for those prioritizing absorption and direct utilization, often preferred over the HCl form.
88 Performance 
B-Complex '100'
Solgar
4.7
★★★★★
(446 ratings)
This Solgar B-Complex offers 100mg of B6 alongside a full spectrum of other B vitamins from a premium brand, making it a superior choice for holistic B vitamin support rather than just isolated B6.
83 Budget 
B-6 100 mg
Source Naturals
4.7
★★★★★
(819 ratings)
This Source Naturals product offers the same 100mg dose of Pyridoxine HCl at a slightly higher, but still very competitive, price per serving, providing similar efficacy for general B6 needs.
80 Budget 
B-6 100 mg
Nature's Bounty
4.8
★★★★★
(269 ratings)
Nature's Bounty provides a comparable 100mg Pyridoxine HCl supplement, offering a reliable option from another well-known brand, though at a slightly higher cost per serving compared to NOW.
78 Budget 
Folic Acid B6 & B12
Mason Natural
4.8
★★★★★
(2530 ratings)
This Mason Natural product offers 50mg of B6 as part of a B-complex with Folic Acid and B12, providing broader B vitamin support at a very low price point, making it a cost-effective option if other B vitamins are also desired.
82 Value
B-50
NOW
4.7
★★★★★
(30076 ratings)
This NOW B-50 Complex provides a balanced dose of 50mg B6 along with other essential B vitamins, offering more comprehensive support for overall metabolic health from a trusted brand at a reasonable price.
85 Value
B-50 Complex
21st Century
4.7
★★★★★
(8446 ratings)
The 21st Century B-50 Complex offers 50mg of B6 as part of a comprehensive B vitamin blend, delivering excellent value for a full spectrum B-complex, especially for budget-conscious consumers seeking broader benefits.
80 Value
B-50 Complex 50 mg
Source Naturals
4.7
★★★★★
(2521 ratings)
Source Naturals' B-50 Complex provides 50mg of B6 and other B vitamins, representing good value for a reputable brand's comprehensive B-complex, addressing various metabolic needs.
95 Performance
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
4.8
★★★★★
(1062 ratings)
This Swanson product offers Vitamin B6 in its active P-5-P form, which is more bioavailable and often preferred by nutritionists, potentially providing more direct and efficient benefits for individuals seeking superior absorption.
90 Performance
Vitamin B-6 50 mg
Nature's Way
4.8
★★★★★
(1720 ratings)
Nature's Way provides a 50mg P-5-P supplement, which is a highly bioavailable form of B6, making it a better choice for those prioritizing absorption and direct utilization, often preferred over the HCl form.
88 Performance
B-Complex '100'
Solgar
4.7
★★★★★
(446 ratings)
This Solgar B-Complex offers 100mg of B6 alongside a full spectrum of other B vitamins from a premium brand, making it a superior choice for holistic B vitamin support rather than just isolated B6.