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Vitamin D3 50 mcg (2000 IU) + K2 90 mcg

4.9
★ ★ ★ ★ ★
(4626 ratings)
Vitamin K 90 mcg
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Score84
A balanced D3 and MK-7 formula with clear forms and useful amounts. Two dry capsules per serving reduce convenience and lack an identified fat carrier.
How scoring works
Capsule
Quantity:30 Capsule(s) • (15 servings)
Goals:
Bone Health
Heart Health
Cardiovascular Support

Score 84

A balanced D3 and MK-7 formula with clear forms and useful amounts. Two dry capsules per serving reduce convenience and lack an identified fat carrier.
How scoring works
$8.42($0.56 per serving)
Pure Formulas
$ 8.42
iHerb
$ 8.42
iHerb
$ 8.42
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Analysis

The serving combines cholecalciferol with a practical amount of menaquinone-7. Both forms are clearly identified and address complementary vitamin D and K pathways.

No carrier oil or other fat-based delivery is listed in the supplied record. Taking the capsules with a meal containing fat may be more practical for absorption of these fat-soluble vitamins.

Two capsules per serving are unnecessary for such a simple formula but still manageable. It fits users who want moderate D3 with MK-7 and do not mind the short package duration.

Who is it for
  • Adults seeking moderate D3 with MK-7
  • People comfortable with two capsules per serving
  • Users who can take it with a fat-containing meal
Best for
  • Daily D3 and K2 support
  • Bone calcium-management nutrition
  • Moderate combined dosing

Pros

  • Uses cholecalciferol
  • Provides 90 mcg of MK-7
  • Clearly states both active amounts
  • Avoids unrelated ingredients

Cons

  • Requires two capsules
  • No fat carrier is stated
  • Package provides only 15 servings
  • Less convenient than one-unit alternatives

Warnings

  • Vitamin K2 can oppose warfarin and related vitamin K antagonists.
  • Count the 50 mcg vitamin D amount alongside other D-containing supplements.

Nutrient quality

94 Highest impact

Cholecalciferol and menaquinone-7 are well-regarded forms. Both vitamins are supplied in meaningful amounts for bone support.

Ingredient transparency

82 Highest impact

Every active ingredient has a specific amount. Inactive ingredients are not supplied.

Customer satisfaction

74 High impact

The supplied average indicates very strong aggregate satisfaction. No detailed experience reports are available to identify repeated complaints or confirm perceived benefits.

Value for money

83 Highest impact

The high-quality forms support reasonable value for the cost. Serving value appears moderate for a focused vitamin combination.

Report analysis

Goals

Bone Health
Impact
Highest effect
A Goal FitA Strength of SupportB- CoverageA+ Formula Quality
Vitamin K · 90 mcgVitamin D · 50 mcg

Vitamin D3 and MK-7 form a strong pair for calcium absorption and placement in bone. Human evidence supports both nutrient roles, although the formula does not supply the calcium or protein matrix itself.

The 90 mcg MK-7 amount is clinically aligned, while the 50 mcg vitamin D3 amount suits common supplemental use. The dry capsules lack a stated lipid carrier. MK-7 can oppose warfarin, so users of that anticoagulant need consistent intake and prescriber-guided monitoring.

Study evidence
Vitamin K Supportive 78 studies
Heart Health
Impact
Highest effect
B+ Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 90 mcgVitamin D · 50 mcg

Vitamin D3 and MK-7 form a well-aligned calcium-management pair with meaningful vascular relevance. The combination supports proper calcium use but does not address lipids, blood pressure, or cardiac cellular energy.

Both vitamin forms and amounts are clearly disclosed, although the dry capsule lacks a stated lipid carrier. People taking warfarin or other vitamin K antagonist medicines should keep vitamin K intake consistent and follow their prescriber’s guidance.

Study evidence
Vitamin K Mixed 62 studies
Cardiovascular Support
Impact
Highest effect
B- Goal FitA+ Strength of SupportC CoverageA+ Formula Quality
Vitamin K · 90 mcgVitamin D · 50 mcg

Vitamin D3 and MK-7 form a logical pair for calcium handling and vascular support. Both amounts are clearly disclosed and reach practical daily ranges.

The formula does not address lipids, blood pressure, cardiac energy, or endothelial nitric oxide. MK-7 can counteract warfarin, so people using vitamin K antagonist anticoagulants need consistent intake and clinician-guided monitoring.

Study evidence
Vitamin D Mixed 170 studies
Vitamin K Supportive 40 studies

Ingredients

IngredientAmount per serving
Vitamin D (Cholecalciferol)
50 mcg
Vitamin K2 (Menaquinone-7)
90 mcg
Gluten Free Adults 18–50
Report overview
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

MK-7 is supplied at a clinically aligned dose alongside vitamin D. The generic source lacks branded or all-trans verification, and the dry capsules provide no stated lipid carrier or meal guidance. Vitamin K2 can interfere with vitamin K antagonist anticoagulants such as warfarin, so users of those medicines need clinician-guided consistency.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  2. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
    Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Meta-analysis6,759 participants19 studies pooledBone Health forVitamin K
  3. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  4. Comparison of concurrent treatment with vitamin K2 and risedronate compared with treatment with risedronate alone in patients with osteoporosis: Japanese Osteoporosis Intervention Trial-03.
    Tanaka S; Miyazaki T; Uemura Y; Miyakawa N; Gorai I; Nakamura T; Fukunaga M; Ohashi Y; Ohta H; Mori S; Hagino H; Hosoi T; Sugimoto T; Itoi E; Orimo H; Shiraki M · Journal of bone and mineral metabolism · 2018
    Randomized trial1,874 participantsBone Health forVitamin K
  5. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  6. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  7. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  8. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  9. Interventions to Attenuate Cardiovascular Calcification Progression: A Systematic Review of Randomized Clinical Trials.
    Murali S; Smith ER; Tiong MK; Tan SJ; Toussaint ND · Journal of the American Heart Association · 2024
    Systematic review9,901 participants49 studies pooledCardiovascular Support forVitamin K
  10. Intake of dietary phylloquinone and menaquinones and risk of stroke.
    Vissers LE; Dalmeijer GW; Boer JM; Monique Verschuren WM; van der Schouw YT; Beulens JW · Journal of the American Heart Association · 2014
    Cohort study35,476 participantsCardiovascular Support forVitamin K
  11. Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease.
    van den Heuvel EG; van Schoor NM; Lips P; Magdeleyns EJ; Deeg DJ; Vermeer C; den Heijer M · Maturitas · 2014
    Cohort study577 participantsCardiovascular Support forVitamin K
  12. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  13. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  14. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  15. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support forVitamin D
  16. A Randomized Trial of Vitamin D Supplementation on Vascular Function in CKD.
    Kumar V; Yadav AK; Lal A; Kumar V; Singhal M; Billot L; Gupta KL; Banerjee D; Jha V · Journal of the American Society of Nephrology : JASN · 2017
    Randomized trial120 participantsCardiovascular Support forVitamin D
  17. Randomized, placebo-controlled, double-blind clinical trial on the contributions of vitamin D in the control of cardiovascular risk factors, depressive symptoms and suicide risk.
    Porto C; Petribu K; Barbosa N; Magalhães R; Lira C; Porto AB; Markman-Filho B; Lordsleem A; Calado E; Magalhães J; Sougey E; Silva T; Junio A; Bandeira F; Leão R · American heart journal plus : cardiology research and practice · 2025
    Randomized trial224 participantsCardiovascular Support forVitamin D
  18. Dose responses of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency: A placebo controlled randomized trial.
    Raed A; Bhagatwala J; Zhu H; Pollock NK; Parikh SJ; Huang Y; Havens R; Kotak I; Guo DH; Dong Y · PloS one · 2017
    Randomized trial70 participantsCardiovascular Support forVitamin D
  19. Paricalcitol and endothelial function in chronic kidney disease trial.
    Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
    Randomized trial88 participantsCardiovascular Support forVitamin D
  20. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  21. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  22. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K