Product Image

Ocu Support

NOW
4.6
★ ★ ★ ★ ★
(928 ratings)
Zinc 25 mg
Selenium 100 mcg
Vitamin A 25000 IU
Rutin 100 mg
Riboflavin 20 mg
Green Tea 150 mg
Product Image
Score78
A strong eye formula with branded lutein, bilberry, NAC, EGCG, and quality mineral forms. Very high beta-carotene is a decisive drawback for current or former smokers.
How scoring works
Quantity:120 Capsule(s) • (40 servings)
Goals:
Immunity
Vision Support
Skin Health
General Health

Score 78

A strong eye formula with branded lutein, bilberry, NAC, EGCG, and quality mineral forms. Very high beta-carotene is a decisive drawback for current or former smokers.
How scoring works

Also available as

1 option
Clinical Strength • 90 Capsule(s) servings Clinical Strength • 90 Capsule(s) • 30 servings $19.70 ($0.65 per serving)
$23.10($0.57 per serving)
Daily Vita
$ 23.10
iHerb
$ 24.49
Vitacost
$ 24.49
Amazon
$ 23.44
Pure Formulas
$ 24.09
Report prices

Analysis

The formula supplies 10 mg branded lutein, zeaxanthin, bilberry anthocyanins, NAC, EGCG, rutin, zinc, and selenium. These ingredients cover macular pigments, antioxidant defenses, and several supportive pathways for vision.

Zinc and selenium use well-regarded forms, and natural vitamin E adds further antioxidant support. The 25,000 IU beta-carotene amount is unusually high, while zeaxanthin is modest relative to lutein.

Three capsules fit adults seeking a comprehensive eye formula who are not current or former smokers. Medication use and total antioxidant intake deserve review because vitamin E, green tea, zinc, and beta-carotene are all substantial.

Who is it for
  • Nonsmoking adults seeking broad eye support
  • People wanting branded lutein with bilberry and NAC
  • Users who have reviewed total zinc and vitamin E intake
Best for
  • Macular pigment support
  • Broad ocular antioxidant coverage
  • Combining lutein with bilberry and zinc

Pros

  • Provides 10 mg branded FloraGLO lutein
  • Includes bilberry anthocyanins, NAC, EGCG, and rutin
  • Uses zinc monomethionine and selenomethionine
  • Contains natural vitamin E
  • Covers several vision-support pathways

Cons

  • Beta-carotene amount is very high
  • Zeaxanthin is modest beside lutein
  • Requires three capsules
  • High zinc and vitamin E limit casual stacking

Warnings

  • Current and former smokers should avoid high-dose supplemental beta-carotene because it may increase lung-cancer risk in these groups.
  • The substantial vitamin E amount may increase bleeding tendency with anticoagulant or antiplatelet medicines.
  • Twenty-five milligrams of zinc should not be stacked long term without accounting for copper intake.
  • Green-tea extract may not suit people with caffeine sensitivity if residual caffeine is present but undisclosed.

Nutrient quality

75 High impact

Well-chosen eye nutrients and useful forms provide a strong targeted formula. Aggressive beta-carotene and vitamin E amounts substantially reduce balance.

.

Ingredient transparency

81 Highest impact

Active ingredients and standardized markers are clearly disclosed without hidden blends. Missing intake directions and capsule excipients are the main transparency gaps.

.

Customer satisfaction

69 High impact

Aggregate satisfaction is strong and supported by a substantial evidence base. No firsthand experience details are supplied, so recurring complaints and purpose alignment cannot be checked.

.

Value for money

84 Highest impact

Useful ingredients and a sound category position support good value. The package compares well with similar products.

.
Report analysis

Goals

Immunity
Immunity
Impact
Highest effect
A- Goal FitB+ Strength of SupportA- CoverageA- Formula Quality
Vitamin C · 300 mgZinc · 25 mgVitamin A · 25000 IUSelenium · 100 mcg

Vitamin A, vitamin C, zinc monomethionine, L-selenomethionine, N-acetyl cysteine, and bilberry anthocyanins cover several immune and antioxidant pathways. Zinc and selenium use high-quality forms and reach substantial amounts.

The product is designed for eye health, and green tea potency is not quantified despite naming EGCG. The very high beta-carotene amount is unsuitable for current and former smokers because supplemental high-dose beta-carotene may add risk for that group.

Study evidence
Green Tea Not classified 2 studies
Selenium Mixed 37 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Zinc Supportive 73 studies
Vision Support
Vision Support
Impact
High effect
B+ Goal FitB Strength of SupportB- CoverageC+ Formula Quality
Zinc · 25 mgVitamin E · 134 mgVitamin C · 300 mgVitamin A · 25000 IU

Lutein, zeaxanthin, zinc, vitamins C and E, and bilberry give the formula clear ocular relevance. The branded lutein amount is useful, but zeaxanthin is low compared with the balance used in established macular formulas.

High beta-carotene and the absence of copper keep it from closely matching an AREDS2-style design. Current and former smokers should avoid the high-dose beta-carotene because it may add risk for that group.

Study evidence
Zinc Supportive 39 studies
Skin Health
Skin Health
Impact
High effect
B- Goal FitA- Strength of SupportC CoverageC- Formula Quality
Zinc · 25 mgVitamin C · 300 mgSelenium · 100 mcgGreen Tea · 150 mgVitamin E · 134 mg

High-dose beta-carotene, vitamin C, vitamin E, zinc, and lutein provide strong antioxidant coverage with some skin-repair support. OptiZinc and branded lutein improve selected forms.

The eye-health formula lacks collagen, copper, ceramides, and hydration actives, so skin benefits remain mostly antioxidant. Its many ocular ingredients do not create a comprehensive skin formula.

Study evidence
Vitamin C Supportive 53 studies
Vitamin E Supportive 38 studies
Zinc Supportive 66 studies
General Health
General Health
Impact
High effect
C- Goal FitB+ Strength of SupportD+ CoverageB+ Formula Quality
Selenium · 100 mcgZinc · 25 mgVitamin C · 300 mg

A focused eye-support formula contributes antioxidants and trace minerals but does not cover general health broadly. Lutein, zeaxanthin, bilberry, premium zinc, selenium, and antioxidant vitamins are disclosed in credible forms.

Its narrow visual-health emphasis leaves many foundational nutrient and systemic pathways unaddressed. The formula is coherent for eye support but works poorly as a stand-alone general-health product.

Study evidence
Selenium Supportive 70 studies
Zinc Supportive 60 studies
Hair Health
Hair Health
Impact
Moderate effect
C- Goal FitB- Strength of SupportC- CoverageD- Formula Quality
Zinc · 25 mgVitamin C · 300 mg

Bioavailable zinc, selenium, vitamin C, vitamin E, and N-acetyl cysteine support follicle nutrition and antioxidant defenses. Zinc reaches a substantial amount in a well-regarded monomethionine form.

The eye-health formula lacks iron, biotin, vitamin D, structural protein, and an androgen-targeted active. Its high beta-carotene content is unsuitable for current or former smokers because supplemental high doses may add lung-cancer risk.

Study evidence
Selenium Disputed 7 studies
Vitamin C Mixed 5 studies
Vitamin E No effect 3 studies
Zinc Supportive 22 studies
Nail Health
Nail Health
Impact
Moderate effect
D Goal FitC+ Strength of SupportD+ CoverageD+ Formula Quality

Zinc monomethionine, vitamin C, selenium, and N-acetyl cysteine provide a limited mineral and sulfur-supportive link to nails. The mineral forms are well characterized and fully disclosed.

No biotin, collagen, keratin, or silicon is present, and the product is designed for eye health. Its nail contribution is narrow and largely dependent on correcting zinc or antioxidant nutrient gaps.

Study evidence
Selenium Adverse 1 study
Vitamin C Supportive 1 study
Zinc No effect 1 study
Metabolism Boost
Metabolism Boost
Impact
Moderate effect
C- Goal FitC+ Strength of SupportD- CoverageF Formula Quality
Riboflavin · 20 mgZinc · 25 mgGreen Tea · 150 mg

Green tea extract provides the main direct link to metabolic support, while selenium, zinc, and riboflavin serve broader nutritional roles. Most of the formula is designed for eye and antioxidant support rather than metabolism.

The green tea extract is identified with EGCG, but the available label data do not state the standardized EGCG or caffeine amount. Strong doses of eye-focused carotenoids and antioxidants make the product coherent for another goal, not for broad metabolic pathway coverage.

Study evidence
Green Tea Supportive 31 studies
Riboflavin Mixed 5 studies
Selenium Mixed 28 studies
Zinc Supportive 12 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene)
 25000 IU
Vitamin C (Ascorbic Acid)
 300 mg
Vitamin E (D-Alpha-Tocopheryl Succinate)
 134 mg
Riboflavin (Vitamin B2)
 20 mg
Zinc (L-OptiZinc Monomethionine)
 25 mg
Selenium (L-Selenomethionine)
 100 mcg
Bilberry extract (Anthocyanins)
 100 mg
Lutein (FloraGLO Marigold flowers extract)
 10 mg
Green Tea extract (EGCG)
 150 mg
N-Acetyl Cysteine
100 mg
Rutin powder (Sophora japonica)
 100 mg
Zeaxanthin (FloraGLO Marigold flowers extract)
 500 mcg
Gluten Free Adults 18–50 Kosher Dairy Free
Report overview
Zinc (L-OptiZinc Monomethionine) · 25 mg OverallScore82
A+ Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

A premium monomethionine source supports absorption and stomach tolerance. The label clearly states 25 mg of elemental zinc, a robust amount that is unlikely to disrupt copper balance. The multi-unit serving may be burdensome, while cost efficiency is poor for the dose.

View ingredientView products
Selenium (L-Selenomethionine) · 100 mcg OverallScore77
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

Explicit L-selenomethionine offers high bioavailability and clear isomer disclosure. The maintenance dose leaves a wide safety margin below the daily upper limit. The very high standardized cost makes selenium efficiency weak despite other included nutrients.

View ingredientView products
Vitamin A (Beta-Carotene) · 25000 IU OverallScore67
D+ Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyA+ Value

A very high beta-carotene dose is paired with an unspecified source and a dry capsule. Its low standardized cost is favorable, but the amount exceeds the preferred routine range. Current and former smokers should avoid high-dose beta-carotene supplements because this intake may add risk for that group.

View ingredientView products
Loading alternative details
83 Performance

ACES+Zn

Carlson
<p>Natural vitamin E, buffered vitamin C, zinc citrate, and selenomethionine provide a concise antioxidant formula with strong forms. Vitamin E remains high for routine use and the formula omits the original lutein, zeaxanthin, and bilberry.</p>
76 Performance

Immune Active

Metagenics
<p>Vitamin C, zinc glycinate, N-acetylcysteine, decaffeinated green tea, and quercetin create a coherent antioxidant alternative without the original extreme beta-carotene amount. Zinc is still high for long-term use and the green-tea marker content is not stated.</p>
75 Performance

Clinical Strength Ocu Support

NOW
<p>Lutein, natural vitamin E, carotenoids, zinc, and multiple antioxidants keep the formula closely centered on vision support. Vitamin A and vitamin E remain relatively high, while several accessory antioxidants are only modestly dosed.</p>
77 Budget

Healthy Eyes Lutein and Antioxidants

21st Century
<p>Lutein with antioxidant vitamins preserves the basic vision-support role at a much lower serving cost. The lutein dose is modest and zinc oxide reaches a high amount, so form quality and long-term mineral balance remain limitations.</p>
76 Budget

Ocuvite Lutein & Antioxidants

Bausch & Lomb
<p>Marigold-derived lutein with antioxidant vitamins provides a lower-cost route to basic eye support. Lutein remains modest and zinc oxide is high, but the overall formula is less crowded than the original.</p>
76 Budget

Immufight Daily defense

Solaray
<p>Buffered vitamin C, vitamin D3, zinc citrate, and selenomethionine provide lower-cost antioxidant and immune support with favorable mineral forms. It lacks lutein and zeaxanthin for direct vision support, and grapefruit-seed extract may alter exposure to some medicines.</p>
81 Value

ACES+Zn

Carlson
<p>Buffered vitamin C, natural vitamin E, zinc citrate, and selenomethionine combine favorable forms with competitive serving value. Vitamin E is high and dedicated eye carotenoids are absent, but the antioxidant core is easier to assess.</p>
74 Value

PreserVision AREDS Soft Gels

Bausch & Lomb
<p>Substantial antioxidant vitamins and zinc provide a focused vision-support pattern at favorable serving value. Beta-carotene, synthetic vitamin E, zinc oxide, and cupric oxide are weaker choices, and current or former smokers should avoid concentrated beta-carotene supplements.</p>
72 Value

Multi Men's Prime

Swanson
<p>Broad vitamins and several good mineral forms offer much stronger general-nutrition value at a very low serving cost. The crowded formula uses many lightly dosed botanicals and provides less targeted vision support than the original.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  2. Treatment response to antioxidants and zinc based on CFH and ARMS2 genetic risk allele number in the Age-Related Eye Disease Study.
    Awh CC; Hawken S; Zanke BW · Ophthalmology · 2015
    Randomized trial989 participantsVision Support forZinc
  3. Efficacy of Selenium Supplementation in Graves' Orbitopathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Trial Sequential Analysis.
    Kostadinov N; Kirovakov Z; Penchev P · Journal of clinical medicine · 2026
    Meta-analysis303 participants5 studies pooledVision Support forSelenium
  4. Selenium, selenoproteins and vision.
    Flohé L · Developments in ophthalmology · 2005
    Narrative reviewVision Support forSelenium
  5. Toxic risks and nutritional benefits of traditional diet on near visual contrast sensitivity and color vision in the Brazilian Amazon.
    Fillion M; Lemire M; Philibert A; Frenette B; Weiler HA; Deguire JR; Guimarães JR; Larribe F; Barbosa F; Mergler D · Neurotoxicology · 2014
    Cross-sectional study228 participantsVision Support forSelenium
  6. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  7. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  8. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  9. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  10. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  11. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  12. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  13. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  14. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  15. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  16. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  17. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
    Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
    Observational study1,407 participantsHair Health forSelenium
  18. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
    Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
    Randomized trial64 participantsHair Health forSelenium
  19. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
    Meta-analysis764 participantsHair Health forSelenium
  20. Scientific opinion on the tolerable upper intake level for selenium.
    EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
    Systematic reviewHair Health forSelenium
  21. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  22. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  23. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  24. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  25. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  26. Effects of tocotrienol supplementation on hair growth in human volunteers.
    Beoy LA; Woei WJ; Hay YK · Tropical life sciences research · 2014
    Randomized trial38 participantsHair Health forVitamin E
  27. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
    Zhou L; Zhu W; Chen Y · Frontiers in nutrition · 2026
    Meta-analysis1,658 participants19 studies pooledHair Health forVitamin E
  28. Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss: A Systematic Review.
    Drake L; Reyes-Hadsall S; Martinez J; Heinrich C; Huang K; Mostaghimi A · JAMA dermatology · 2023
    Systematic review30 studies pooledHair Health forVitamin E
  29. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  30. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  31. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  32. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  33. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  34. Preventive effects of tea and tea catechins against influenza and acute upper respiratory tract infections: a systematic review and meta-analysis
    Mai Umeda, Takeichiro Tominaga, Kazuya Kozuma, Hidefumi Kitazawa, Daisuke Furushima, Masanobu Hibi, Hiroshi Yamada · European Journal of Nutrition · 2021
    Meta-analysis3,748 participants10 studies pooledImmunity forGreen Tea
  35. Prevention of Acute Upper Respiratory Infections by Consumption of Catechins in Healthcare Workers: A Randomized, Placebo-Controlled Trial
    Daisuke Furushima, Takuma Nishimura, Norikata Takuma, Ryo Iketani, Tomohito Mizuno, Yuji Matsui, Tohru Yamaguchi, Yu Nakashima, Shinji Yamamoto, Masanobu Hibi, Hiroshi Yamada · Nutrients · 2019
    Randomized trial255 participantsImmunity forGreen Tea
  36. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  37. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  38. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  39. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  40. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  41. Depressed immune response to tetanus in children with vitamin A deficiency.
    Semba RD; Muhilal; Scott AL; Natadisastra G; Wirasasmita S; Mele L; Ridwan E; West KP; Sommer A · The Journal of nutrition · 1992
    Randomized trial236 participantsImmunity forVitamin A
  42. Impact of a single megadose of vitamin A at delivery on breastmilk of mothers and morbidity of their infants.
    Roy SK; Islam A; Molla A; Akramuzzaman SM; Jahan F; Fuchs G · European journal of clinical nutrition · 1997
    Randomized trial50 participantsImmunity forVitamin A
  43. Vitamin A supplementation reduces measles morbidity in young African children: a randomized, placebo-controlled, double-blind trial.
    Coutsoudis A; Broughton M; Coovadia HM · The American journal of clinical nutrition · 1991
    Randomized trial60 participantsImmunity forVitamin A
  44. Vitamin A supplementation enhances specific IgG antibody levels and total lymphocyte numbers while improving morbidity in measles.
    Coutsoudis A; Kiepiela P; Coovadia HM; Broughton M · The Pediatric infectious disease journal · 1992
    Randomized trial60 participantsImmunity forVitamin A
  45. Vitamin A supplementation reduces the monocyte chemoattractant protein-1 intestinal immune response of Mexican children.
    Long KZ; Santos JI; Estrada Garcia T; Haas M; Firestone M; Bhagwat J; Dupont HL; Hertzmark E; Rosado JL; Nanthakumar NN · The Journal of nutrition · 2006
    Randomized trial127 participantsImmunity forVitamin A
  46. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  47. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  48. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  49. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  50. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  51. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  52. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  53. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  54. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  55. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  56. Effect of green tea on glucose control and insulin sensitivity: a meta-analysis of 17 randomized controlled trials.
    Liu K; Zhou R; Wang B; Chen K; Shi LY; Zhu JD; Mi MT · The American journal of clinical nutrition · 2013
    Meta-analysis1,133 participants17 studies pooledMetabolism Boost forGreen Tea
  57. Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans.
    Venables MC; Hulston CJ; Cox HR; Jeukendrup AE · The American journal of clinical nutrition · 2008
    Randomized trial23 participantsMetabolism Boost forGreen Tea
  58. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans.
    Dulloo AG; Duret C; Rohrer D; Girardier L; Mensi N; Fathi M; Chantre P; Vandermander J · The American journal of clinical nutrition · 1999
    Randomized trial10 participantsMetabolism Boost forGreen Tea
  59. A 60-Day Green Tea Extract Supplementation Counteracts the Dysfunction of Adipose Tissue in Overweight Post-Menopausal and Class I Obese Women.
    Rondanelli M; Gasparri C; Perna S; Petrangolini G; Allegrini P; Fazia T; Bernardinelli L; Cavioni A; Mansueto F; Oberto L; Patelli Z; Tartara A; Riva A · Nutrients · 2022
    Randomized trial28 participantsMetabolism Boost forGreen Tea
  60. Epigallocatechin gallate alleviates non-alcoholic fatty liver disease through the inhibition of the expression and activity of Dipeptide kinase 4.
    Yang M; Yan R; Sha R; Wang X; Zhou S; Li B; Zheng Q; Cao Y · Clinical nutrition (Edinburgh, Scotland) · 2024
    Randomized trialMetabolism Boost forGreen Tea
  61. Disorders of flavin adenine dinucleotide metabolism: MADD and related deficiencies.
    Mereis M; Wanders RJA; Schoonen M; Dercksen M; Smuts I; van der Westhuizen FH · The international journal of biochemistry & cell biology · 2024
    Systematic reviewMetabolism Boost forRiboflavin
  62. Anaemia during pregnancy: could riboflavin deficiency be implicated?
    Duffy B; McNulty H; Ward M; Pentieva K · The Proceedings of the Nutrition Society · 2026
    Narrative reviewMetabolism Boost forRiboflavin
  63. Effects of riboflavin and folic acid supplementation on plasma homocysteine levels in healthy subjects.
    Chuang CZ; Boyles A; Legardeur B; Su J; Japa S; Lopez-S A · The American journal of the medical sciences · 2006
    Non-randomized trial34 participantsMetabolism Boost forRiboflavin
  64. Riboflavin and riboflavin-derived cofactors in adolescent girls with anorexia nervosa.
    Capo-chichi CD; Guéant JL; Lefebvre E; Bennani N; Lorentz E; Vidailhet C; Vidailhet M · The American journal of clinical nutrition · 1999
    Clinical trial34 participantsMetabolism Boost forRiboflavin
  65. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledMetabolism Boost forRiboflavin
  66. Effects of selenium supplementation on glucose homeostasis, inflammation, and oxidative stress in gestational diabetes: Randomized, double-blind, placebo-controlled trial.
    Asemi Z; Jamilian M; Mesdaghinia E; Esmaillzadeh A · Nutrition (Burbank, Los Angeles County, Calif.) · 2016
    Randomized trial70 participantsMetabolism Boost forSelenium
  67. Metabolic response to selenium supplementation in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial.
    Jamilian M; Razavi M; Fakhrie Kashan Z; Ghandi Y; Bagherian T; Asemi Z · Clinical endocrinology · 2016
    Randomized trial70 participantsMetabolism Boost forSelenium
  68. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forSelenium
  69. The Effects of Selenium Supplementation on Gene Expression Related to Insulin and Lipid Metabolism, and Pregnancy Outcomes in Patients with Gestational Diabetes Mellitus: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Karamali M; Dastyar F; Badakhsh MH; Aghadavood E; Amirani E; Asemi Z · Biological trace element research · 2021
    Randomized trial36 participantsMetabolism Boost forSelenium
  70. Glycemic and lipid responses to selenium-enriched vs. zeaxanthin-enriched eggs in patients with type 2 diabetes: a 12-week randomized controlled trial.
    Niu X; Zhang Y; Liu Y; Zhu Y; Fang B; Hu C; Xu X; Wang R; Sang Y; Zhang Q; Guo J · Frontiers in nutrition · 2026
    Randomized trial58 participantsMetabolism Boost forSelenium
  71. The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects: A phase 2 randomized, placebo-controlled trial with a multi-arm, parallel-group design.
    Karandish M; Mozaffari-Khosravi H; Mohammadi SM; Cheraghian B; Azhdari M · Phytotherapy research : PTR · 2021
    Randomized trial84 participantsMetabolism Boost forZinc
  72. Relationship between zinc and glucose metabolism in Japanese adults.
    Suka M; Tsuruta H; Takao T; Yanagisawa H · Diabetology international · 2026
    Cross-sectional study533 participantsMetabolism Boost forZinc
  73. Zinc and the Innovative Zinc-α2-Glycoprotein Adipokine Play an Important Role in Lipid Metabolism: A Critical Review.
    Banaszak M; Górna I; Przysławski J · Nutrients · 2021
    Narrative reviewMetabolism Boost forZinc
  74. Capsaicin and Zinc Signalling Pathways as Promising Targets for Managing Insulin Resistance and Type 2 Diabetes.
    Ferdowsi PV; Ahuja KDK; Beckett JM; Myers S · Molecules (Basel, Switzerland) · 2023
    Narrative reviewMetabolism Boost forZinc
  75. Zinc and Diabetes: A Connection between Micronutrient and Metabolism.
    Ahmad R; Shaju R; Atfi A; Razzaque MS · Cells · 2024
    Narrative reviewMetabolism Boost forZinc
  76. Acute selenium toxicity associated with a dietary supplement.
    MacFarquhar JK; Broussard DL; Melstrom P; Hutchinson R; Wolkin A; Martin C; Burk RF; Dunn JR; Green AL; Hammond R; Schaffner W; Jones TF · Archives of internal medicine · 2010
    Observational study201 participantsNail Health forSelenium
  77. Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
    Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
    Other20 participantsNail Health forVitamin C
  78. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forZinc
  79. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  80. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  81. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  82. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  83. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  84. Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis.
    Javanbakht MH; Keshavarz SA; Djalali M; Siassi F; Eshraghian MR; Firooz A; Seirafi H; Ehsani AH; Chamari M; Mirshafiey A · The Journal of dermatological treatment · 2011
    Randomized trial45 participantsSkin Health forVitamin E
  85. Serum vitamin E levels and chronic inflammatory skin diseases: A systematic review and meta-analysis.
    Liu X; Yang G; Luo M; Lan Q; Shi X; Deng H; Wang N; Xu X; Zhang C · PloS one · 2022
    Meta-analysis20 studies pooledSkin Health forVitamin E
  86. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forVitamin E Skin Health forZinc
  87. Effects of tocotrienol on aging skin: A systematic review.
    Ghazali NI; Mohd Rais RZ; Makpol S; Chin KY; Yap WN; Goon JA · Frontiers in pharmacology · 2022
    Systematic reviewSkin Health forVitamin E
  88. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
    Stahl W; Heinrich U; Jungmann H; Sies H; Tronnier H · The American journal of clinical nutrition · 2000
    Randomized trialSkin Health forVitamin E
  89. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  90. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  91. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  92. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  93. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  94. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  95. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  96. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc