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Extend-Release Magnesium

4.7
★ ★ ★ ★ ★
(3183 ratings)
Magnesium 250 mg
Product Image
Score80
A practical, affordable extended-release blend with a useful amount, but an undisclosed oxide share creates absorption uncertainty.
How scoring works
Capsule
Quantity:60 Capsule(s) • (60 servings)
Goals:
General Health
Energy
Stress Relief
Heart Health
Bone Health
Digestive Health
Cardiovascular Support

Score 80

A practical, affordable extended-release blend with a useful amount, but an undisclosed oxide share creates absorption uncertainty.
How scoring works
$9.75($0.16 per serving)
Vitacost
$ 9.75
iHerb
$ 9.75
Pure Formulas
$ 9.75
Vitacost
$ 9.75
iHerb
$ 9.75
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Analysis

Magnesium citrate supports moderate absorption, while extended-release oxide may spread digestive exposure over time. Because the formula does not state how much each source contributes, systemic delivery is difficult to predict.

The named elemental amount is appropriate for many routine magnesium needs without reaching the largest doses in this group. A single capsule and extended-release format may suit users who prefer simple, steady use.

Serving value is favorable according to the collection analysis. The formula remains focused on one mineral and does not provide a cofactor or the certainty of a fully chelated product.

Who is it for
  • Adults wanting a once-daily extended-release magnesium
  • Budget-conscious users comfortable with a mixed citrate-and-oxide formula
Best for
  • Routine magnesium support
  • Users seeking a moderate amount in one capsule

Pros

  • Includes magnesium citrate
  • Useful stated elemental amount
  • Extended-release format
  • Low serving cost

Cons

  • Contains lower-absorption oxide
  • Form proportions are unknown
  • No complementary cofactor

Warnings

  • Citrate and oxide can still cause loose stools or abdominal discomfort despite the extended-release design.
  • People with impaired kidney function may not clear supplemental magnesium safely.
  • Magnesium can reduce absorption of some antibiotics and thyroid medicine, so follow the prescribed spacing instructions.

Nutrient quality

83 Highest impact

Citrate improves the form mix and the supplemental amount is practical. Unknown form proportions and reliance on extended-release oxide limit absorption confidence.

Ingredient transparency

76 High impact

The total active amounts and forms are stated. Form proportions, full directions, and non-active ingredients remain unclear.

Customer satisfaction

71 High impact

The aggregate satisfaction metric is strong and supported by a useful volume of ratings. Specific firsthand feedback is absent, so recurring complaints and purpose fit cannot be assessed.

Value for money

90 Highest impact

A practical serving, focused formula, and low serving cost support good value. Unclear form proportions keep it below fully citrate or glycinate products on quality.

Report analysis

Goals

General Health
Stress Resilience
General Health
Impact
Highest effect
A Goal FitA- Strength of SupportD+ CoverageA Formula Quality
Magnesium · 250 mg

Magnesium directly supports energy metabolism, muscle function, and nervous-system balance. The focused formula provides a meaningful elemental amount.

Citrate adds a moderately absorbed source, while oxide has weaker absorption and an undisclosed share of the blend. Extended release may improve timing but does not resolve that form-quality uncertainty.

Study evidence
Magnesium Supportive 114 studies
Energy
Energy
Impact
High effect
A- Goal FitB+ Strength of SupportD+ CoverageA Formula Quality
Magnesium · 250 mg

A useful magnesium amount supports ATP-related enzyme activity and normal muscle function. Citrate improves the profile of an otherwise oxide-based extended-release formula.

The contribution of each source is not disclosed, so effective absorption remains uncertain. The single-mineral design is focused but does not address alertness or stress resilience.

Study evidence
Magnesium Supportive 4 studies
Stress Relief
Calm and Tension Relief
Stress Relief
Impact
High effect
B- Goal FitB Strength of SupportD+ CoverageA- Formula Quality
Magnesium · 250 mg

Magnesium supports nervous-system regulation and muscle relaxation, with the clearest benefit when intake is inadequate. Its physiological role is established, while human evidence for reducing perceived stress in otherwise replete users is less robust than for targeted adaptogens or theanine.

The 250 mg elemental magnesium amount meets a meaningful stress-support range. Citrate improves the blend, while the undisclosed proportion of extended-release oxide leaves absorption uncertain.

Study evidence
Magnesium Supportive 13 studies
Heart Health
Healthy Blood Pressure
Heart Health
Impact
High effect
B- Goal FitB+ Strength of SupportD+ CoverageB+ Formula Quality
Magnesium · 250 mg

A meaningful magnesium amount supports normal rhythm and vascular tone. Citrate improves the blend, while the unknown share of lower-absorption oxide leaves some uncertainty.

The focused formula provides depth in one established heart-related mineral pathway. It does not address lipids, cellular energy, or homocysteine balance.

Study evidence
Magnesium Supportive 158 studies
Bone Health
Bone Mineral Density
Bone Health
Impact
High effect
B+ Goal FitB- Strength of SupportC- CoverageB Formula Quality
Magnesium · 250 mg

The extended-release blend provides a practical magnesium amount for bone and mineral metabolism. Magnesium citrate improves the blend and the dose is fully disclosed.

An unknown share comes from poorly absorbed oxide, and no calcium, vitamin D, or vitamin K is included. It works best as a focused magnesium supplement rather than a comprehensive skeletal formula.

Study evidence
Magnesium Supportive 48 studies
Digestive Health
Bowel Regularity
Digestive Health
Impact
High effect
B- Goal FitB Strength of SupportD+ CoverageA Formula Quality
Magnesium · 250 mg

Magnesium citrate provides direct stool-softening potential, while extended-release oxide may prolong exposure. The formula remains focused on motility rather than broad gut health.

The total amount is useful and both forms are named, though their proportions are not. Loose stools or cramping are possible, and kidney impairment raises the risk from magnesium accumulation.

Study evidence
Magnesium Supportive 50 studies
Cardiovascular Support
Heart Muscle and Rhythm
Cardiovascular Support
Impact
High effect
B- Goal FitB Strength of SupportD+ CoverageA Formula Quality
Magnesium · 250 mg

Magnesium provides direct support for vascular tone and normal cardiac electrical activity. Human evidence is relevant, but the product does not address lipid management, nitric oxide production, or cardiac energy.

The 250 mg elemental amount is useful and extended release may improve tolerance. A mixed citrate and oxide system provides uncertain absorption because the proportion of each form is not stated.

Study evidence
Magnesium Supportive 123 studies

Ingredients

IngredientAmount per serving
Magnesium (Magnesium Citrate, ZumXR Magnesium Oxide)
 250 mg
Gluten Free Adults 18–50
Report overview
Magnesium (Magnesium Citrate, ZumXR Magnesium Oxide) · 250 mg OverallScore61
F Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyC Value

The formula supplies a useful elemental amount through citrate and extended-release oxide. Citrate may improve the blend, but the oxide proportion is not stated and the release system does not establish chelation quality. A low serving cost makes it practical, with absorption uncertainty as the main trade-off.

View ingredientView products
Loading alternative details
81 Performance

Ultra-Mag

Source Naturals
<p>A broad organic magnesium blend supplies strong form diversity and a substantial amount at an economical cost. Compared with Extend-Release Magnesium, its magnesium form and supporting ingredients may be a better fit where citrate improves the blend, but the oxide proportion and absorption benefit of the release system are not established, while the label does not clarify each form share, while high supplemental magnesium and prolonged B6 use may affect tolerability.</p>
85 Performance

Magnesium Bisglycinate Chelate

Healthy Origins
<p>TRAACS magnesium bisglycinate provides premium absorption quality, a useful elemental amount, and exceptional serving value in a clean powder. Compared with Extend-Release Magnesium, its magnesium form and supporting ingredients may be a better fit where citrate improves the blend, but the oxide proportion and absorption benefit of the release system are not established, while the product is narrow rather than comprehensive, and its relatively weak satisfaction metric deserves consideration despite the strong formula.</p>
75 Performance

NeuroMag

Designs for Health
<p>Branded magnesium L-threonate provides a well-characterized specialty form at its typical elemental amount. Compared with Extend-Release Magnesium, its magnesium form and supporting ingredients may be a better fit where citrate improves the blend, but the oxide proportion and absorption benefit of the release system are not established, while strong customer sentiment cannot fully offset a very high serving cost.</p>
80 Budget

Magnesium Caps 500 mg

Life Extension
<p>Citrate, succinate, and a named glycinate chelate strengthen a multi-form magnesium blend, while oxide lowers average absorption. Its lower recurring cost than Extend-Release Magnesium makes it a more economical magnesium option, while the large supplemental amount may cause diarrhea or cramping, although the very low serving cost provides strong value for users who tolerate it.</p>
79 Budget

Target-Mins Magnesium Caps With Silica 300 mg

Country Life
<p>The mineral blend combines useful magnesium forms with oxide and a substantial horsetail-derived silica amount. Its lower recurring cost than Extend-Release Magnesium makes it a more economical magnesium option, while strong customer sentiment and highly economical servings make the larger supply attractive.</p>
74 Budget

Magnesium 500 mg

Nature's Life
<p>Absorbable forms improve the blend, but magnesium oxide lowers its overall absorption quality. Its lower recurring cost than Extend-Release Magnesium makes it a more economical magnesium option, while active doses are stated, while missing excipient and full use details limit transparency.</p>
84 Value

Magnesium Bisglycinate Chelate

Healthy Origins
<p>TRAACS magnesium bisglycinate provides premium absorption quality and a useful elemental amount in a clean tablet. Compared with Extend-Release Magnesium, its magnesium profile offers a practical quality-to-cost trade-off despite no confirmed cost advantage, while the focused formula offers strong value but remains limited to one foundational mineral pathway.</p>
91 Value

Krebs Magnesium Potassium Complex

Nature's Way
<p>Magnesium lysinate and malate provide favorable forms at a useful amount, with a modest potassium contribution. Compared with Extend-Release Magnesium, its magnesium profile offers a practical quality-to-cost trade-off despite no confirmed cost advantage, while the focused formula offers excellent serving value.</p>
88 Value

Magnesium Bisglycinate Powder

NOW
<p>Magnesium bisglycinate supplies a well-absorbed form at a practical, moderate amount. Compared with Extend-Release Magnesium, its magnesium profile and lower recurring cost create a more favorable quality-to-cost balance, while no meaningful dose or formulation concern is evident from the supplied facts.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  2. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  3. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  4. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  5. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  6. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  7. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  8. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  9. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  10. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  11. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  12. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  13. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  14. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  15. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  16. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  17. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  18. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  19. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  20. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  21. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  22. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  23. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  24. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  25. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  26. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  27. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  28. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  29. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  30. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  31. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  32. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium