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Gastro-Ease

4.7
★ ★ ★ ★ ★
(3777 ratings)
Zinc 16.5 mg
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Score68

A balanced zinc amount is paired with weak form disclosure and a specialized digestive ingredient. It makes more sense for its digestive purpose than as a zinc supplement.

How scoring works
Capsule
Quantity:60 Capsule(s) • (60 servings)
Goals:
General Health
Immunity

Score 68

A balanced zinc amount is paired with weak form disclosure and a specialized digestive ingredient. It makes more sense for its digestive purpose than as a zinc supplement.

How scoring works
$33.00($0.55 per serving)
Vitacost
$ 33.00
iHerb
$ 33.00
Pure Formulas
$ 33.00
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Analysis

The capsule provides 16.5 mg of elemental zinc without naming its chemical form. That omission leaves absorption and stomach tolerance uncertain.

Pylopass Lactobacillus reuteri gives the formula a digestive focus rather than broader zinc support. Listing the bacterial ingredient only by weight does not show a viable organism count.

The zinc amount is appropriate for maintenance and stays below the adult upper intake level. Buyers who only need zinc would get clearer form disclosure and better value from a dedicated product.

Who is it for
  • Adults specifically seeking the zinc and Pylopass combination
  • People whose main interest is digestive support with added zinc
Best for
  • Specialized digestive-use routines
  • Users who value the two-ingredient combination more than zinc value

Pros

  • Balanced elemental zinc amount
  • Stays below the adult upper intake level
  • Simple two-active capsule
  • Clearly names the Pylopass ingredient

Cons

  • Does not identify the zinc compound
  • Bacterial ingredient lacks a viable count
  • Poor value when judged for zinc alone
  • Limited relevance to non-digestive goals

Warnings

  • 16.5 mg may cause nausea when taken on an empty stomach.
  • Long-term use alongside other zinc supplements can reduce copper absorption, so total zinc intake matters.
  • Zinc can reduce absorption of tetracycline or quinolone antibiotics, so dose spacing should follow the medicine instructions.

Nutrient quality

77 High impact

The zinc compound is not identified, so absorption and tolerance cannot be evaluated. The amount stays within a practical maintenance range for most adults.

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Ingredient transparency

67 High impact

The elemental amount is shown, but the zinc form is missing. Directions and inactive ingredients are not supplied, limiting full label transparency.

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Customer satisfaction

72 High impact

The supplied aggregate rating indicates strong customer satisfaction. Specific comments are unavailable, so complaint patterns and intended-use fit cannot be verified.

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Value for money

56 Moderate impact

The digestive specialty ingredient may justify some cost, but value is poor when judged for zinc delivery. Missing zinc-form detail further weakens comparison.

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Report analysis

Goals

General Health
General Health
Impact
High effect
B- Goal FitB- Strength of SupportC- CoverageA- Formula Quality
Zinc · 16.5 mg

A maintenance-range zinc amount contributes to foundational immune and metabolic support. Pylopass Lactobacillus reuteri is more specifically aimed at digestive use, so the formula is not a broad daily wellness supplement.

The elemental zinc amount and bacterial ingredient are individually listed, but the zinc compound is missing. That omission makes absorption and tolerance harder to assess despite otherwise useful dose disclosure.

Study evidence
Zinc Supportive 60 studies
Immunity
Immunity
Impact
High effect
A Goal FitC- Strength of SupportD+ CoverageB Formula Quality
Zinc · 16.5 mg

Zinc supports foundational immune, enzyme, antioxidant, and tissue-repair functions. The formula focuses mainly on zinc-dependent pathways, with limited added mineral breadth.

The 50 mg zinc amount exceeds the adult tolerable upper intake level and is poorly suited to routine long-term use. A daily 50 mg zinc amount exceeds the adult upper limit and may cause nausea or copper deficiency with extended use.

Study evidence
Zinc Supportive 73 studies
Skin Health
Skin Health
Impact
Moderate effect
C- Goal FitC+ Strength of SupportD CoverageC Formula Quality
Zinc · 16.5 mg

Zinc provides a meaningful amount for normal skin repair and cell turnover. The zinc compound is not identified, which prevents a useful assessment of absorption or tolerance.

Lactobacillus reuteri is included for digestive use and does not add established skin-specific support in this formulation. The combination is therefore narrower and less transparent than a focused, well-specified zinc product.

Study evidence
Zinc Supportive 66 studies
Testosterone Support
Testosterone Support
Impact
Moderate effect
C- Goal FitB- Strength of SupportF CoverageD Formula Quality
Zinc · 16.5 mg

The 16.5 mg zinc amount may support normal testosterone production when zinc status is low. The added Lactobacillus reuteri is aimed at gastrointestinal use and does not have established direct endocrine value here.

Zinc is dosed within the stated target range, but its chemical form is not disclosed. The two-ingredient formula is coherent for digestive support rather than for broad testosterone support.

Study evidence
Zinc Disputed 7 studies
Hair Health
Hair Health
Impact
Moderate effect
C Goal FitC+ Strength of SupportF CoverageD Formula Quality
Zinc · 16.5 mg

A maintenance amount of zinc can support follicle function when intake is inadequate. The rationale is credible for deficiency, while the added bacterium has no provided hair-specific evidence.

The zinc amount is appropriate for routine nutritional support and is not merely a trace inclusion. The elemental amount is stated, but the missing zinc compound prevents assessment of absorption.

Study evidence
Zinc Supportive 22 studies

Ingredients

IngredientAmount per serving
Zinc
16.5 mg
Pylopass Lactobacillus reuteri
100 mg
Adults 18–50
Report overview
Zinc · 16.5 mg OverallScore47
F Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyF Value

The maintenance-range zinc amount is appropriate for routine use, and the vegetarian capsule is convenient. The zinc compound is not identified, preventing a meaningful assessment of absorption or tolerance. A very high serving cost makes it poor value as a zinc supplement, even though the combination formula may serve a different digestive purpose.

View ingredientView products
Loading alternative details
82 Performance

Zinc 30 mg

Nature's Life
A clearly named zinc compound makes absorption and tolerance easier to assess than with the original label. Zinc picolinate with copper provides a coherent, economical mineral-balance formula. The zinc amount is substantial, and repeated copper entries make the total less clear than it should be.
81 Performance

Zinc Picolinate 22 mg

Solgar
A clearly named zinc compound makes absorption and tolerance easier to assess than with the original label. Picolinate offers strong absorption potential at a useful maintenance amount. The focused formula and very low serving cost make it a practical choice without an obvious dosing excess.
81 Performance

Chelated Zinc 30 mg

Swanson
A clearly named zinc compound makes absorption and tolerance easier to assess than with the original label. A branded glycinate chelate offers excellent absorption potential at a substantial amount. The simple capsule is highly economical, though sustained use without copper may impair mineral balance.
94 Budget

Zinc-L-Carnosine Complex

California Gold Nutrition
Lower recurring cost makes this a more economical zinc option than the original while retaining a clearly characterized active profile. Zinc L-carnosine provides a well-regarded complex at a moderate zinc amount, creating a focused and balanced formula. The label separately lists zinc, the complex, and carnosine, which is informative but can make the dose relationship look more complicated than it is.
82 Budget

L-OptiZinc 30 mg

NOW
Lower recurring cost makes this a more economical zinc option than the original while retaining a clearly characterized active profile. Zinc monomethionine provides excellent absorption potential at a substantial amount. A small copper addition is helpful but remains too low to fully balance sustained high zinc use.
82 Budget

Zinc Picolinate 25 mg

Thompson
Lower recurring cost makes this a more economical zinc option than the original while retaining a clearly characterized active profile. Picolinate is a well-absorbed zinc form, and the amount is meaningful without crossing the usual adult upper limit. The simple formula and very low serving cost make it a practical zinc supplement.
90 Value

Zinc Chelate 30 mg

Nature's Way
The combination of form quality, practical dosing, and serving value provides a stronger quality-to-cost balance than the original. Zinc bisglycinate provides a well-absorbed form at a robust daily amount. The focused capsule is clearly labeled and very inexpensive, but no copper is included.
90 Value

OptiZinc

Source Naturals
The combination of form quality, practical dosing, and serving value provides a stronger quality-to-cost balance than the original. Zinc methionine provides a well-absorbed chelated form at a robust amount, and added copper offers partial balance. The copper amount is small relative to the zinc, but the formula is safer for sustained use than unbalanced high-dose options.
89 Value

Chelated Zinc 30 mg

Carlson
The combination of form quality, practical dosing, and serving value provides a stronger quality-to-cost balance than the original. Glycinate chelate offers high-quality absorption and tolerance at a robust amount. Zinc glycinate chelate is a highly regarded form for absorption and tolerance.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  2. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  3. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  4. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  5. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  6. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  7. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  8. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  9. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  10. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  11. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  12. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  13. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  14. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  15. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  16. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  17. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  18. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  19. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  20. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forZinc
  21. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  22. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  23. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  24. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  25. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc