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GABA 750 mg

The Vitamin Shoppe
4.8
★ ★ ★ ★ ★
(20 ratings)
GABA 750 mg
Product Image
Score77
A focused standard GABA product delivering 750 mg in a single tablet. The added calcium is nutritionally minor and the GABA source is not verified.
How scoring works
Quantity:180 Tablet(s) • (180 servings)
Goals:
Stress Relief
Sleep Support

Score 77

A focused standard GABA product delivering 750 mg in a single tablet. The added calcium is nutritionally minor and the GABA source is not verified.
How scoring works
$34.99($0.19 per serving)
iHerb
$ 34.99
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Analysis

The single tablet supplies 750 mg of standard GABA. The formula also has 37 mg of calcium from dicalcium phosphate.

The upper-range amount may suit people who already know they respond to GABA. It is less appropriate as a first trial because stronger drowsiness can make daytime use or dose adjustment difficult.

The main limitation is that the added calcium is nutritionally minor and the GABA source is not verified. The product fits adults seeking a high-strength tablet in a large package, provided sedative stacking and next-day drowsiness are considered.

Who is it for
  • adults seeking a high-strength tablet in a large package
  • people seeking focused relaxation support without a multi-herb blend
Best for
  • evening relaxation
  • supporting a calmer bedtime routine

Pros

  • Clearly states 750 mg of GABA
  • Single tablet is easy to use
  • 37 mg of calcium from dicalcium phosphate

Cons

  • The added calcium is nutritionally minor and the GABA source is not verified
  • Higher fixed amount offers limited titration flexibility
  • Focused formula does not address broader causes of poor sleep or stress

Warnings

  • GABA may cause drowsiness, dizziness, or reduced alertness.
  • Alcohol, sleep medicines, benzodiazepines, antihistamines, or other sedatives may intensify drowsiness when combined with GABA.
  • Avoid driving or operating machinery until the response to the 750 mg amount is known.

Nutrient quality

79 High impact

The hard tablet and generic GABA source are conventional rather than premium. The GABA amount reaches the high end of the common standalone range, and the high GABA amount provides depth within one calming pathway.

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Ingredient transparency

80 Highest impact

Every listed active has a specific amount and no proprietary blend obscures the formula. Complete intake directions and inactive ingredients are not supplied, leaving part of the label unverified.

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Customer satisfaction

58 Moderate impact

The supplied aggregate satisfaction level is exceptionally strong. The very small feedback volume makes the aggregate uncertain.

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Value for money

88 Highest impact

The high amount supports the modest cost despite basic form quality. The serving provides strong value, and the product is cost-competitive but lacks premium source or delivery features.

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Report analysis

Goals

Stress Relief
Stress Relief
Impact
Highest effect
B+ Goal FitA- Strength of SupportC- CoverageA+ Formula Quality
GABA · 750 mg

GABA directly targets inhibitory neurotransmitter signaling and is supplied at a substantial amount. The formula is focused on a calming pathway rather than broad stress resilience.

The active amount is clear, but the source is unbranded and a hard tablet offers no delivery advantage. Oral GABA response varies because central nervous-system exposure is not fully predictable.

Study evidence
GABA Supportive 6 studies
Sleep Support
Sleep Support
Impact
High effect
C- Goal FitB+ Strength of SupportD+ CoverageA- Formula Quality

GABA targets inhibitory signaling and relaxation, but oral absorption into the brain is uncertain. The single-ingredient formula is calming rather than broadly sleep focused.

The amount sits at the upper end of the useful range and is clearly stated. A conventional tablet and unbranded source add no delivery advantage.

Study evidence
GABA Supportive 4 studies

Ingredients

IngredientAmount per serving
Calcium (Dicalcium Phosphate)
 37 mg
GABA
750 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
GABA · 750 mg OverallScore74
C+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB- Value

The GABA dose sits at the upper end of the preferred range and is clearly stated. An unbranded source and hard-pressed tablet keep ingredient and delivery quality conventional. Its low serving cost offers good value for the active amount.

View ingredientView products
Loading alternative details
74 Performance

Liposomal GABA

Quicksilver Scientific
<p>240 mg GABA with 100 mg L-theanine and phosphatidylcholine broadens the original's single-ingredient approach and may better support relaxation through complementary pathways. The supplied data do not establish how much the liposomal delivery changes absorption, and the serving cost is high.</p>
85 Performance

Pharma GABA 250 mg

Natural Factors Stress-Relax
<p>250 mg fermented branded GABA provides clearer source definition than the original's generic GABA. The branded source improves ingredient definition, although oral GABA effects can vary and drowsiness remains possible.</p>
84 Performance

GABA 500 mg

NOW
<p>500 mg GABA with 2 mg vitamin B6 provides a more conservative amount than the original, which may suit users who are sensitive to drowsiness. Generic sourcing and uncertain oral brain availability limit confidence, and drowsiness remains possible.</p>
84 Budget

GABA

NOW
<p>Lower serving cost and 500 mg GABA make this a more economical option for the same GABA-focused sleep and stress goals. Generic sourcing and uncertain oral brain availability limit confidence, and drowsiness remains possible.</p>
81 Budget

GABA 750 mg

Source Naturals Serene Science
<p>Lower serving cost and 750 mg GABA make this a more economical option for the same GABA-focused sleep and stress goals. Generic sourcing and uncertain oral brain availability limit confidence, while the high amount may increase drowsiness.</p>
83 Budget

GABA 500 mg

Nutricost
<p>Lower serving cost and 500 mg GABA with 2 mg vitamin B6 make this a more economical option for the same GABA-focused sleep and stress goals. Generic sourcing and uncertain oral brain availability limit confidence, and drowsiness remains possible.</p>
83 Value

GABA 500 mg

NOW
<p>Lower serving cost paired with 500 mg GABA with 2 mg vitamin B6 creates a stronger balance of focused calming support and value than the original. Generic sourcing and uncertain oral brain availability limit confidence, and drowsiness remains possible.</p>
83 Value

GABA 500 mg

Swanson
<p>Lower serving cost paired with 500 mg GABA creates a stronger balance of focused calming support and value than the original. Generic sourcing and uncertain oral brain availability limit confidence, and drowsiness remains possible.</p>
81 Value

GABA Powder

Source Naturals Serene Science
<p>Lower serving cost paired with 750 mg GABA creates a stronger balance of focused calming support and value than the original. Generic sourcing and uncertain oral brain availability limit confidence, while the high amount may increase drowsiness.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
    Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
    Randomized trial63 participantsStress Relief forGABA
  2. GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
    Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
    Randomized trial30 participantsStress Relief Sleep Support forGABA
  3. Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
    Byun JI; Shin YY; Chung SE; Shin WC · Journal of clinical neurology (Seoul, Korea) · 2020
    Randomized trial40 participantsSleep Support forGABA
  4. Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.
    Imafuku F; Yamamoto K; Tanaka E; Aoki R; Nishino S · Nutrients · 2023
    Randomized trial160 participantsSleep Support forGABA
  5. Reduced γ-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: a link to major depressive disorder?
    Plante DT; Jensen JE; Schoerning L; Winkelman JW · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
    Case-control study40 participantsSleep Support forGABA
  6. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
    Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H · Journal of nutritional science and vitaminology · 2011
    Clinical trial30 participantsStress Relief forGABA
  7. Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality.
    Meyerhoff DJ; Mon A; Metzler T; Neylan TC · Sleep · 2014
    Case-control study45 participantsStress Relief forGABA
  8. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsStress Relief forGABA