Product Image

Super B-Complex with Folic Acid plus Vitamin C

Nature's Bounty
4.7
★ ★ ★ ★ ★
(71274 ratings)
Niacin 25 mg
Biotin 1000 mcg
Thiamin 25 mg
Riboflavin 20 mg
Vitamin B12 100 mcg
Product Image
Score84

A practical, broad B complex with moderate vitamin B6 and a substantial biotin amount. Conventional forms are the main quality trade-off.

How scoring works
Quantity:150 Tablet(s) • (150 servings)
Goals:
General Health
Energy
Metabolism Boost
Hair Health

Score 84

A practical, broad B complex with moderate vitamin B6 and a substantial biotin amount. Conventional forms are the main quality trade-off.

How scoring works
$13.43($0.08 per serving)
Walmart
$ 13.43
iHerb
$ 14.19
Amazon
$ 14.19
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Analysis

The tablet covers the main B vitamins with 25 mg thiamine, 20 mg riboflavin, 25 mg niacinamide, 5 mg vitamin B6, and 666 mcg DFE folate. Those amounts support normal energy metabolism without pushing vitamin B6 into the very high range found in many B-100 formulas.

Cyanocobalamin and standard pyridoxine are conventional rather than activated forms. The clearly disclosed 1,000 mcg biotin amount is substantial, while 60 mg vitamin C adds modest antioxidant support.

A one-tablet serving and large supply suit general daily use when a broad B complex is wanted. Hair support remains limited because biotin alone does not address protein, iron, zinc, or other common nutritional factors.

Who is it for
  • Adults seeking broad B-vitamin coverage
  • People wanting moderate rather than extreme vitamin B6
  • Users who prefer one daily tablet
Best for
  • Normal energy metabolism
  • General B-vitamin coverage
  • Biotin supplementation

Pros

  • Broad B-vitamin profile
  • Moderate 5 mg vitamin B6 amount
  • Clearly disclosed 1,000 mcg biotin
  • Includes 60 mg vitamin C
  • Large serving supply

Cons

  • Uses conventional cyanocobalamin
  • Folate form is not specified
  • Limited choline and no broader mineral coverage

Warnings

  • The 1,000 mcg biotin amount can interfere with some laboratory tests
  • Tell the testing provider about biotin use before blood work
  • People sensitive to niacin should note the 25 mg niacinamide amount

Nutrient quality

80 Highest impact

The formula covers the major B vitamins at useful amounts for routine metabolic support. Cyanocobalamin, pyridoxine, ordinary riboflavin, and unspecified folate limit form quality, while the biotin amount is unusually high.

Ingredient transparency

84 Highest impact

The major B vitamins have separate amounts and no hidden blend obscures the core formula. Complete usage directions and the inactive-ingredient list are not supplied here.

Customer satisfaction

78 High impact

The very strong average rating is supported by an exceptionally large review base. No review excerpts describe tolerance, effectiveness, or repeated complaints, so those experiences remain uncertain.

Value for money

93 Highest impact

A long supply and focused nutrient profile provide excellent everyday value. Basic forms prevent premium quality, but few low-value additions dilute the serving.

Report analysis

Goals

General Health
Daily Energy Vitality
General Health
Impact
Highest effect
A- Goal FitB- Strength of SupportB CoverageB+ Formula Quality
Folate · 666 mcg DFEVitamin B12 · 100 mcgVitamin C · 60 mg

A broad B-vitamin profile supports energy metabolism, red blood cell formation, and basic nutritional coverage. Vitamin C adds modest antioxidant support.

Cyanocobalamin, folic acid, and pyridoxine are serviceable but less optimized than active coenzyme forms. The 1,000 mcg biotin amount may interfere with some laboratory tests and should be reported before blood work.

Study evidence
Vitamin B12 Adverse 66 studies
Vitamin C Supportive 56 studies
Energy
Energy
Impact
High effect
A- Goal FitB- Strength of SupportC+ CoverageA- Formula Quality
Vitamin B5 · 5.5 mgRiboflavin · 20 mgThiamin · 25 mgVitamin B12 · 100 mcg

The B-complex directly supports enzymes involved in converting food into usable cellular energy. Meaningful amounts of thiamine, riboflavin, niacin, B6, folate, and B12 make the metabolic coverage stronger than a token energy label.

Several forms are basic rather than active, including cyanocobalamin and pyridoxine, and the coated tablet adds no absorption advantage. The high biotin amount can interfere with thyroid, cardiac, and hormone laboratory tests, so it should be disclosed before blood testing.

Study evidence
Riboflavin Mixed 6 studies
Thiamin Disputed 12 studies
Vitamin B12 Disputed 14 studies
Metabolism Boost
Metabolic B-Vitamins
Metabolism Boost
Impact
High effect
C Goal FitC+ Strength of SupportC CoverageA- Formula Quality
Biotin · 1000 mcgNiacin · 25 mgVitamin B12 · 100 mcgRiboflavin · 20 mgThiamin · 25 mgVitamin B5 · 5.5 mgVitamin B6 · 5 mg

A broad B-complex supports the enzymes that convert carbohydrate, fat, and protein into cellular energy. The formula is better suited to correcting nutrient gaps than actively increasing energy expenditure.

Several B vitamins are supplied at useful amounts, but most use standard forms and vitamin B12 is cyanocobalamin. The biotin amount may interfere with some laboratory tests and should be disclosed before blood work.

Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Riboflavin Mixed 5 studies
Thiamin Supportive 11 studies
Vitamin B12 Supportive 10 studies
Hair Health
Hair Health
Impact
Moderate effect
D+ Goal FitB- Strength of SupportC CoverageC Formula Quality
Biotin · 1000 mcgVitamin C · 60 mg

Biotin, folate, B12, and vitamin C provide nutritional cofactors for rapidly dividing follicle cells, but benefits are most likely when a deficiency exists. The broad B-complex lacks iron, zinc, structural amino acids, or a targeted hormonal ingredient.

Most amounts are clear, with D-biotin identified, while cyanocobalamin and pyridoxine are basic forms. The 1,000 mcg biotin amount can interfere with some laboratory tests, so clinicians and laboratories need to know about its use.

Study evidence
Biotin Supportive 4 studies
Folate Mixed 15 studies
Vitamin B12 Disputed 17 studies
Vitamin C Mixed 5 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
 60 mg
Thiamine (Thiamine Mononitrate, Vitamin B1)
 25 mg
Riboflavin (Vitamin B2)
 20 mg
Niacin (Niacinamide)
 25 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 5 mg
Folate
666 mcg DFE
Vitamin B12 (Cyanocobalamin)
 100 mcg
Biotin (D-Biotin)
 1000 mcg
Pantothenic Acid (D-Calcium Pantothenate)
 5.5 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free Vegetarian
Report overview
Niacin (Niacinamide) · 25 mg OverallScore84
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

The B-complex provides a clearly identified niacinamide amount appropriate for routine multi-nutrient use. Its coated tablet has no stated release technology, but the dose and form are straightforward. A low serving cost makes it an efficient source within a broader B-vitamin formula.

View ingredientView products
Biotin (D-Biotin) · 1000 mcg OverallScore73
A Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyC Value

The 1,000 mcg amount offers moderate potency and explicitly uses the active d-biotin isomer. Standard tablet delivery is less clean than a capsule or liquid, while the broader B-complex supports neutral value. The biotin dose may interfere with some laboratory tests, so it should be disclosed before blood work.

View ingredientView products
Thiamin (Thiamine Mononitrate, Vitamin B1) · 25 mg OverallScore65
B- Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyD- Value

The 25 mg thiamine mononitrate amount provides moderate potency rather than a high-dose targeted amount. The form and dose are clearly disclosed, but the coated tablet offers no specialized absorption technology. Value for thiamine alone is weak, and the 1,000 mcg biotin amount can interfere with some laboratory tests.

View ingredientView products
Loading alternative details
85 Performance

B-Complex Plus

Pure Encapsulations
<p>Methylfolate, methylcobalamin, P-5-P, and activated riboflavin improve form quality substantially over the original basic forms. Niacin is elevated, but restrained vitamin B6 and full B-complex coverage suit routine use better than many high-potency formulas.</p>
82 Performance

High Potency Vitamin B Complex

Lake Avenue Nutrition
<p>Active riboflavin, P-5-P, methylfolate, and methylcobalamin provide more refined forms plus choline and pantothenic acid. The high niacin blend may cause flushing or stomach upset, making it more potent but less gentle than the original.</p>
79 Performance

Coenzyme B-Complex Advanced

Country Life
<p>Active B-vitamin forms and PQQ provide broader metabolic support than the original conventional B-complex. Aggressive vitamin B6 and niacin reduce suitability for routine use, so the form-quality advantage comes with a higher dosing burden.</p>
81 Budget

B-Complex with Folic Acid plus Vitamin C

Nature's Bounty
<p>Broad B-vitamin coverage with vitamin C closely matches the original at a lower serving cost. Forms remain conventional and thiamine entries are duplicated, but the generally sensible amounts preserve its everyday-use profile.</p>
80 Budget

B-Complex plus Vitamin C

21st Century
<p>Vitamin C, thiamine, riboflavin, niacin, vitamin B6, and pantothenic acid provide an inexpensive energy-metabolism base. Missing folate, vitamin B12, and biotin make it less complete than the original, but the serving cost is lower.</p>
80 Budget

Super Vitamin B-Complex

Spring Valley
<p>Broad measured B-vitamin coverage comes at a lower serving cost and supports the same energy purpose. Chemical forms are not supplied and thiamine is high, so ingredient quality is harder to judge than in the original.</p>
83 Value

High Potency Vitamin B Complex

Lake Avenue Nutrition
<p>Active riboflavin, P-5-P, methylfolate, methylcobalamin, choline, and pantothenic acid offer refined coverage at a modest serving cost. The unclear share of flush-producing nicotinic acid is a trade-off, but the long supply supports value.</p>
74 Value

Advanced Absorption Mega B-Complex

Irwin Naturals
<p>A broad B-vitamin profile with methylcobalamin adds more complete high-potency coverage at a still-modest serving cost. Duplicated entries and substantial vitamin B6 reduce clarity and long-term suitability, but value remains reasonable for occasional targeted use.</p>
76 Value

Biotin Forte

Nature's Way
<p>Biotin, vitamin C, and supporting B vitamins focus more directly on hair-related nutrition at a low serving cost. Elevated vitamin B6 and high biotin still require care with routine use and laboratory testing.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  2. High-dose oral thiamine versus placebo for chronic fatigue in patients with primary biliary cholangitis: A crossover randomized clinical trial.
    Bager P; Bossen L; Gantzel R; Grønbæk H · PloS one · 2024
    Randomized trial36 participantsEnergy forThiamin
  3. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  4. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  5. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health forBiotin
  6. Effects of NAD+ precursor supplementation on glucose and lipid metabolism in humans: a meta-analysis.
    Zhong O; Wang J; Tan Y; Lei X; Tang Z · Nutrition & metabolism · 2022
    Meta-analysis14,750 participants40 studies pooledMetabolism Boost forNiacin
  7. Changes in glucose metabolism, C-reactive protein, and liver enzymes following intake of NAD + precursor supplementation: a systematic review and meta-regression analysis.
    Sohouli MH; Tavakoli S; Reis MG; Hekmatdoost A; Guimarães NS · Nutrition & metabolism · 2024
    Meta-analysis9,256 participants45 studies pooledMetabolism Boost forNiacin
  8. Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults.
    Dhir S; Tarasenko M; Napoli E; Giulivi C · Frontiers in psychiatry · 2026
    Narrative reviewMetabolism Boost forThiamin
  9. Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials.
    Nakanishi N; Abe Y; Matsuo M; Tampo A; Yamada K; Hatakeyama J; Yoshida M; Yamamoto R; Higashibeppu N; Nakamura K; Kotani J · Clinical nutrition (Edinburgh, Scotland) · 2024
    Meta-analysis3,494 participants35 studies pooledMetabolism Boost forThiamin
  10. Disorders of flavin adenine dinucleotide metabolism: MADD and related deficiencies.
    Mereis M; Wanders RJA; Schoonen M; Dercksen M; Smuts I; van der Westhuizen FH · The international journal of biochemistry & cell biology · 2024
    Systematic reviewMetabolism Boost forRiboflavin
  11. Riboflavin and riboflavin-derived cofactors in adolescent girls with anorexia nervosa.
    Capo-chichi CD; Guéant JL; Lefebvre E; Bennani N; Lorentz E; Vidailhet C; Vidailhet M · The American journal of clinical nutrition · 1999
    Clinical trial34 participantsMetabolism Boost forRiboflavin
  12. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  13. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  14. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  15. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Boost forRiboflavin
  16. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  17. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  18. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  19. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  20. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  21. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  22. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  23. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  24. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  25. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsGeneral Health forVitamin B12
  26. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsGeneral Health forVitamin B12
  27. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsGeneral Health forVitamin B12
  28. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsGeneral Health forVitamin B12
  29. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsGeneral Health forVitamin B12
  30. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  31. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  32. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  33. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  34. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  35. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health forBiotin
  36. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  37. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
    Meta-analysis2,538 participants18 studies pooledHair Health forFolate
  38. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forFolate Hair Health forVitamin B12
  39. Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
    Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
    Randomized trialHair Health forFolate
  40. Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
    Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
    Randomized trialHair Health forFolate
  41. Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
    Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
    Randomized trialHair Health forFolate
  42. Factors Associated with Premature Hair Graying in a Young Indian Population.
    Chakrabarty S; Krishnappa PG; Gowda DG; Hiremath J · International journal of trichology · 2016
    Case-control study74 participantsHair Health forVitamin B12
  43. Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
    İritaş SY · Dermatology practical & conceptual · 2026
    Case-control study600 participantsHair Health forVitamin B12
  44. Hair Loss After Laparoscopic Sleeve Gastrectomy.
    Katsogridaki G; Tzovaras G; Sioka E; Perivoliotis K; Zachari E; Magouliotis D; Tasiopoulou V; Chatedaki C; Zacharoulis D · Obesity surgery · 2019
    Cohort study50 participantsHair Health forVitamin B12
  45. Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.
    Sonthalia S; Priya A; Tobin DJ · Indian journal of dermatology · 2022
    Cross-sectional study71 participantsHair Health forVitamin B12
  46. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  47. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  48. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  49. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  50. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  51. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Boost forBiotin
  52. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Boost forBiotin
  53. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Boost forBiotin
  54. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Boost forBiotin
  55. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Boost forBiotin
  56. Niacin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Boost forNiacin
  57. Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans.
    Fangmann D; Theismann EM; Türk K; Schulte DM; Relling I; Hartmann K; Keppler JK; Knipp JR; Rehman A; Heinsen FA; Franke A; Lenk L; Freitag-Wolf S; Appel E; Gorb S; Brenner C; Seegert D; Waetzig GH; Rosenstiel P; Schreiber S; Schwarz K; Laudes M · Diabetes care · 2018
    Clinical trialMetabolism Boost forNiacin
  58. The differential impact of three different NAD+ boosters on circulatory NAD and microbial metabolism in humans.
    Christen S; Redeuil K; Goulet L; Giner MP; Breton I; Rota R; Frézal A; Nazari A; Van den Abbeele P; Godin JP; Nutten S; Cuenoud B · Nature metabolism · 2026
    Randomized trial65 participantsMetabolism Boost forNiacin
  59. Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance.
    Linke A; Sonnabend M; Fasshauer M; Höllriegel R; Schuler G; Niebauer J; Stumvoll M; Blüher M · Atherosclerosis · 2009
    Randomized trial30 participantsMetabolism Boost forNiacin
  60. Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus.
    Vaag A; Skött P; Damsbo P; Gall MA; Richter EA; Beck-Nielsen H · The Journal of clinical investigation · 1991
    Clinical trial12 participantsMetabolism Boost forNiacin
  61. Anaemia during pregnancy: could riboflavin deficiency be implicated?
    Duffy B; McNulty H; Ward M; Pentieva K · The Proceedings of the Nutrition Society · 2026
    Narrative reviewMetabolism Boost forRiboflavin
  62. Effects of riboflavin and folic acid supplementation on plasma homocysteine levels in healthy subjects.
    Chuang CZ; Boyles A; Legardeur B; Su J; Japa S; Lopez-S A · The American journal of the medical sciences · 2006
    Non-randomized trial34 participantsMetabolism Boost forRiboflavin
  63. Plasma vitamin profiles and their associations with metabolic health and mental wellbeing in midlife Asian women.
    Tan KML; Tint MT; Cabral RM; Lau R; Kee MZL; Garg V; De Iorio M; Tan SSL; Eriksson JG · Scientific reports · 2026
    Cohort study662 participantsMetabolism Boost forThiamin
  64. High-resolution plasma metabolomics and thiamine status in critically Ill adult patients.
    Gundogan K; Nellis MM; Ozer NT; Ergul SS; Sahin GG; Temel S; Yuksel RC; Teeny S; Alvarez JA; Sungur M; Jones DP; Ziegler TR · Metabolomics : Official journal of the Metabolomic Society · 2024
    Cross-sectional study76 participantsMetabolism Boost forThiamin
  65. Pathophysiology, prevention, and treatment of beriberi after gastric surgery.
    Wilson RB · Nutrition reviews · 2021
    Narrative reviewMetabolism Boost forThiamin
  66. Red blood cell transketolase activity and the effect of thiamine supplementation in patients with chronic liver disease.
    Rossouw JE; Labadarios D; Krasner N; Davis M; Williams R · Scandinavian journal of gastroenterology · 1978
    Single-arm trialMetabolism Boost forThiamin
  67. Association of maternal vitamin B12 and folate levels in early pregnancy with gestational diabetes: a prospective UK cohort study (PRiDE study).
    Saravanan P; Sukumar N; Adaikalakoteswari A; Goljan I; Venkataraman H; Gopinath A; Bagias C; Yajnik CS; Stallard N; Ghebremichael-Weldeselassie Y; Fall CHD · Diabetologia · 2022
    Cohort study4,746 participantsMetabolism Boost forVitamin B12
  68. First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders.
    Olivieri G; Bordugo A; Burnyte B; Costetti A; Couce ML; Diogo L; Feillet F; Froese DS; Greco B; Gueant JL; Hannibal L; Hörster F; Kožich V; La Marca G; Manoli I; Mochel F; Orazi L; Pérez B; Schiff M; Schwahn BC; Schwartz I; Stepien KM; Sykut-Cegielska J; Tangeraas T; Zetterström RH; Dionisi-Vici C; Huemer M · Journal of inherited metabolic disease · 2026
    Guideline / consensusMetabolism Boost forVitamin B12
  69. Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism.
    Carmel R; Melnyk S; James SJ · Blood · 2003
    Observational study39 participantsMetabolism Boost forVitamin B12
  70. Efficacy of sublingual and oral vitamin B12 versus intramuscular administration: insights from a systematic review and meta-analysis.
    Mazur M; Ndokaj A; Salerno C; Vallone J; Ardan R; Bietolini S; Carrouel F; Wilk A; Sarig R; Ottolenghi L; Bourgeois D · Frontiers in pharmacology · 2026
    Meta-analysis6,098 participants16 studies pooledMetabolism Boost forVitamin B12
  71. Diagnosis and treatment of vitamin B12 deficiency in children.
    Kanvinde P; Khurana R; Mudaliar S · Frontiers in nutrition · 2026
    Narrative reviewMetabolism Boost forVitamin B12