SuppHelper
search
Home›Supplements›Vitamin›Vitamin B6›L-Methionine 500 mg NOW
Product Image

L-Methionine 500 mg

NOW
4.7
★ ★ ★ ★ ★
(6568 ratings)
Vitamin B6 20 mg
Product Image
Score 82

A supplement combining a significant dose of L-Methionine with Vitamin B6 to support metabolic processes and detoxification.

scaleQuantity:100 Capsule(s) • (50 servings)
track_changesGoals:
flag Detoxification
flag Metabolism Boost
flag Cardiovascular Support
flag Heart Health
flag Brain Health
flag Cognitive Support
flag Mental Focus
flag Mood Support

leaderboard Score 82

A supplement combining a significant dose of L-Methionine with Vitamin B6 to support metabolic processes and detoxification.

insightsAnalysis

NOW's L-Methionine 500 mg is primarily focused on delivering this essential amino acid, which participates in protein synthesis and various metabolic processes. L-Methionine is particularly noted for its role in methylation, a crucial biochemical process involved in detoxification and the synthesis of other important compounds like S-adenosylmethionine (SAMe).

To support L-Methionine's metabolic functions, the product also contains a useful amount of Vitamin B6 in the form of Pyridoxine Hydrochloride. B6 is a key co-factor for enzymes involved in amino acid metabolism, including those pathways that interact with methionine. This combination makes it a practical choice for individuals looking to support these specific metabolic and detoxification pathways.

thumb_upPros
  • Provides a substantial 1 gram dose of L-Methionine per serving.
  • Includes Vitamin B6 as a key co-factor for methionine metabolism.
  • Cost-effective with a low price per serving.
  • Simple, direct formulation without unnecessary additives.
thumb_downCons
  • Uses Pyridoxine Hydrochloride, not the active P-5-P form of B6.
  • Not a multi-purpose supplement; very specific in its primary ingredients.
warningWarnings
  • Consult a professional if you have liver conditions or are on other medications.
  • L-Methionine can potentially interact with certain medications; seek professional advice.
  • Store in a cool, dry place to maintain capsule integrity.
flagReport analysis
$13.59($0.27 per serving)
Vitacost
$ 13.59
Daily Vita
$ 13.90
Amazon
$ 13.90
Pure Formulas
$ 14.27
iHerb
$ 14.68
iHerb
$ 14.68
flagReport prices
track_changesGoals
flagDetoxification
Impact
Highest effect
L-Methionine is a precursor for compounds involved in liver detoxification pathways, making it highly relevant for this goal. B6 also supports liver function.
View goal →
flagMetabolism Boost
Impact
Highest effect
Both L-Methionine and B6 are fundamentally involved in numerous metabolic pathways, including protein, fat, and carbohydrate processing.
View goal →
flagHeart Health
Impact
Highest effect
L-Methionine and B6 both play roles in homocysteine metabolism, which is a key factor in cardiovascular wellness.
View goal →
flagCardiovascular Support
Impact
Highest effect
The combined roles of B6 and L-Methionine in managing homocysteine levels are beneficial for supporting cardiovascular health.
View goal →
flagBrain Health
Impact
High effect
L-Methionine supports methylation cycles crucial for brain health and neurotransmitter production. B6 is essential for nerve function and cognitive processes.
View goal →
flagCognitive Support
Impact
High effect
L-Methionine contributes to methylation processes vital for brain function, and B6 supports overall neurological health, which can aid cognition.
View goal →
flagMood Support
Impact
High effect
L-Methionine is a precursor to SAMe, which is involved in neurotransmitter synthesis. B6 also supports mood by aiding in neurotransmitter production.
View goal →
flagMental Focus
Impact
High effect
By supporting brain health and neurotransmitter balance, the ingredients can indirectly contribute to better mental clarity and focus.
View goal →
scienceIngredients
IngredientAmount per serving
Vitamin B6
20 mg
L-Methionine
1 Gram(s)
grain_off Gluten Free person Adults 18–50 free_breakfast Dairy Free
flagReport overview
Vitamin B6 70
This product includes a good, supportive dose of Vitamin B6 (Pyridoxine HCl), crucial for the metabolism of L-Methionine, though it's not the active P-5-P form.
scienceView ingredientinventory_2View products
inventory_2Alternative products
88 Value

B-6 100 mg

NOW
4.8
★★★★★
(7115 ratings)
Offers a significantly higher product score and a much lower price per serving, providing exceptional overall value for foundational B6 support if you are primarily interested in the B6 component.
Other sellers (2)
85 Value

P-5-P 50 mg

Nutricost
4.8
★★★★★
(885 ratings)
Provides the activated P-5-P form of Vitamin B6 at a very reasonable price, representing good value for those seeking this specific form without a high cost.
Other sellers (0)
88 Value

P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength

Swanson
4.8
★★★★★
(2590 ratings)
Delivers an activated form of B6 with a high score for a moderate price, making it a strong contender for overall value, especially for those prioritizing the P-5-P form.
Other sellers (1)
90 Performance

Pyridoxal 5'-Phosphate Caps 100 mg

Life Extension
4.9
★★★★★
(3172 ratings)
This provides Vitamin B6 in its activated P-5-P form, which is often considered more bioavailable and efficient for the body's use, potentially offering superior support for metabolic and cognitive goals compared to the B6 HCl in your current product.
Other sellers (2)
88 Performance

P-5-P 100 mg

Nutricost
4.8
★★★★★
(638 ratings)
With 100 mg of the coenzymated P-5-P form, this alternative may offer enhanced support for various bodily processes, including neurotransmitter synthesis and energy metabolism, potentially surpassing the basic B6 HCl.
Other sellers (0)
88 Performance

B-6 100 mg

NOW
4.8
★★★★★
(7115 ratings)
While still Pyridoxine HCl, this product offers a higher rated B6 supplement at a robust 100 mg dose, which can contribute to overall metabolic and neurological health more directly.
Other sellers (2)
72 Budget

Vitamin B6 100 mg

Vitamatic
4.9
★★★★★
(75 ratings)
Offers a substantial 100 mg dose of Pyridoxine Hydrochloride at a significantly lower cost per serving, making it a much more economical choice for focusing on B6 support.
Other sellers (0)
88 Budget

B-6 100 mg

NOW
4.8
★★★★★
(7115 ratings)
Provides 100 mg of Pyridoxine Hydrochloride from a trusted brand at a substantially lower price per serving, offering excellent B6 value if you're looking for a dedicated B6 supplement.
Other sellers (2)
76 Budget

B-6 100 mg

Source Naturals
4.7
★★★★★
(867 ratings)
This option delivers 100 mg of Pyridoxine Hydrochloride for a very budget-friendly price, an effective way to obtain B6 at a considerably lower cost than your current multi-ingredient product.
Other sellers (1)
88 Value

B-6 100 mg

NOW
4.8
★★★★★
(7115 ratings)
Offers a significantly higher product score and a much lower price per serving, providing exceptional overall value for foundational B6 support if you are primarily interested in the B6 component.
Other sellers (2)
85 Value

P-5-P 50 mg

Nutricost
4.8
★★★★★
(885 ratings)
Provides the activated P-5-P form of Vitamin B6 at a very reasonable price, representing good value for those seeking this specific form without a high cost.
Other sellers (0)
88 Value

P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength

Swanson
4.8
★★★★★
(2590 ratings)
Delivers an activated form of B6 with a high score for a moderate price, making it a strong contender for overall value, especially for those prioritizing the P-5-P form.
Other sellers (1)
90 Performance

Pyridoxal 5'-Phosphate Caps 100 mg

Life Extension
4.9
★★★★★
(3172 ratings)
This provides Vitamin B6 in its activated P-5-P form, which is often considered more bioavailable and efficient for the body's use, potentially offering superior support for metabolic and cognitive goals compared to the B6 HCl in your current product.
Other sellers (2)
88 Performance

P-5-P 100 mg

Nutricost
4.8
★★★★★
(638 ratings)
With 100 mg of the coenzymated P-5-P form, this alternative may offer enhanced support for various bodily processes, including neurotransmitter synthesis and energy metabolism, potentially surpassing the basic B6 HCl.
Other sellers (0)
88 Performance

B-6 100 mg

NOW
4.8
★★★★★
(7115 ratings)
While still Pyridoxine HCl, this product offers a higher rated B6 supplement at a robust 100 mg dose, which can contribute to overall metabolic and neurological health more directly.
Other sellers (2)
flagReport alternatives

SuppHelper

Compare supplements smarter. Science-backed, user-rated, updated daily.

Explore

  • Compare Supplements
  • Health Goals
  • Stacks

Legal

  • Privacy Policy
  • Terms of Use
  • Medical Disclaimer

Stay in the Loop

© 2025 SuppHelper. All rights reserved.