Product Image

Omega-3 2100 with Vitamin K2 & D3 Natural Orange Flavor

Oceanblue Professional
4.9
★ ★ ★ ★ ★
(144 ratings)
Vitamin K 100 mcg
Omega-3 2100 mg
Protein 1 Gram(s)
Product Image
Score75
A concentrated omega-3 formula with useful D3 and branded K2 in two softgels. Ethyl-ester delivery, no separate EPA and DHA amounts, and vitamin K interactions are the main trade-offs.
How scoring works
Quantity:60 Softgel(s) • (30 servings)
Goals:
General Health
Heart Health
Cardiovascular Support
Bone Health
Anti-Aging
Skin Health

Score 75

A concentrated omega-3 formula with useful D3 and branded K2 in two softgels. Ethyl-ester delivery, no separate EPA and DHA amounts, and vitamin K interactions are the main trade-offs.
How scoring works
$42.49($1.41 per serving)
Vitacost
$ 46.75
iHerb
$ 42.49
iHerb
$ 42.49
Vitacost
$ 46.75
Report prices

Analysis

The formula combines a substantial total omega-3 amount with 50 mcg of vitamin D3 and 100 mcg of branded MenaQ7 vitamin K2. That pairing provides coherent support for cardiovascular and bone health in a compact two-softgel serving.

The omega fats are supplied as ethyl esters, which generally depend more on a fat-containing meal for absorption than triglyceride forms. EPA and DHA are not broken out individually, so the exact balance of the two main active omega-3s remains unclear.

People seeking combined omega-3, D3, and K2 support may find the formula convenient despite its premium positioning. Vitamin K2 makes it inappropriate for unsupervised use with warfarin-type anticoagulants, and the high total omega-3 amount also warrants attention alongside blood-thinning therapy.

Who is it for
  • Adults seeking omega-3, vitamin D3, and vitamin K2 together
  • People focused on cardiovascular and bone support
  • Users willing to take the softgels with a fat-containing meal
Best for
  • Combined heart and bone support
  • High-total-omega-3 supplementation
  • Convenient D3 and K2 intake

Pros

  • Provides 2.1 g of total omega-3 fatty acids
  • Includes 50 mcg of vitamin D3
  • Uses branded MenaQ7 vitamin K2
  • Combines three complementary nutrients in two softgels
  • Natural orange flavor may reduce fishy taste

Cons

  • Uses the less readily absorbed ethyl-ester omega-3 form
  • Does not disclose separate EPA and DHA amounts
  • Premium serving cost may limit long-term value
  • Requires a fat-containing meal for better ethyl-ester absorption
  • Not suitable for everyone because of vitamin K2

Warnings

  • Vitamin K2 can interfere with warfarin-type anticoagulants, so use requires clinician-guided monitoring.
  • The high omega-3 amount may increase bleeding tendency when combined with anticoagulant or antiplatelet medicines.
  • Fish-derived omega-3 softgels are unsuitable for people with fish allergy.
  • The 50 mcg vitamin D3 serving should be counted with other vitamin D supplements to avoid unnecessary stacking.

Nutrient quality

90 Highest impact

The omega amount is substantial, while vitamin D3 and branded MK-7 are well-regarded forms. Ethyl esters are less favorable than triglyceride oils, and the EPA-to-DHA profile is not shown.

Ingredient transparency

75 High impact

Total omega fatty acids and both vitamins have specific amounts and forms. The missing EPA and DHA split, daily directions, and inactive ingredients leave important gaps.

Customer satisfaction

66 High impact

The aggregate rating is exceptionally strong, but the evidence base is fairly small. No review excerpts are supplied, so repeated complaints and purpose-specific experiences cannot be assessed.

Value for money

64 Moderate impact

Substantial omega quantity and premium MK-7 support part of the high cost. Missing EPA and DHA amounts make the expensive serving harder to compare with concentrated competitors.

Report analysis

Goals

General Health
General Health
Impact
Highest effect
A+ Goal FitA+ Strength of SupportA- CoverageA+ Formula Quality
Vitamin D · 50 mcgVitamin K · 100 mcg

A substantial omega-3 serving plus vitamin D3 and branded vitamin K2 supports cardiovascular, bone, immune, and inflammatory balance. Each major active has a well-established role in foundational health.

The omega-rich softgel supports absorption of both fat-soluble vitamins, and every active amount is clearly disclosed. Branded MenaQ7 provides strong source identity and the combination is notably coherent. Vitamin K2 can counteract warfarin and other vitamin K antagonist anticoagulants, so users of those medicines should keep intake consistent and coordinate changes with their prescriber.

Study evidence
Vitamin K Supportive 34 studies
Heart Health
Heart Health
Impact
Highest effect
A+ Goal FitA- Strength of SupportA- CoverageA+ Formula Quality
Vitamin K · 100 mcgVitamin D · 50 mcg

A substantial omega-3 serving joins branded MK-7 and vitamin D3 for lipid and calcium-management support. The softgel delivers the fat-soluble vitamins in an appropriate lipid base.

Specific EPA and DHA amounts are not disclosed, limiting judgment of omega-3 potency. Vitamin K2 can oppose warfarin and related medicines, so users need consistent intake and prescriber guidance.

Study evidence
Vitamin K Mixed 62 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A Goal FitA- Strength of SupportB+ CoverageA+ Formula Quality
Vitamin K · 100 mcgVitamin D · 50 mcg

A substantial omega-3 amount combines with vitamin D3 and branded MK-7 for lipid support and calcium management. The formula addresses several cardiovascular mechanisms in a concise softgel design.

EPA and DHA are not disclosed separately, and the omega-3s use an ethyl-ester form. Vitamin K2 can counteract warfarin and other vitamin K antagonist anticoagulants, so intake should remain consistent.

Study evidence
Vitamin D Mixed 170 studies
Vitamin K Supportive 40 studies
Bone Health
Bone Health
Impact
Highest effect
B+ Goal FitA Strength of SupportB- CoverageA- Formula Quality
Vitamin K · 100 mcgVitamin D · 50 mcg

A 100 mcg branded MK-7 dose and 50 mcg vitamin D3 provide a strong regulatory pair for calcium absorption and placement. The omega-rich softgel supports absorption of both fat-soluble vitamins.

No calcium, magnesium, or matrix-building protein is supplied, so users must obtain those structural materials elsewhere. The vitamin K2 amount can oppose warfarin and other vitamin K antagonists, making consistent intake important.

Study evidence
Omega-3 Supportive 32 studies
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
B+ Goal FitB Strength of SupportB+ CoverageA Formula Quality
Omega-3 · 2100 mgVitamin K · 100 mcgVitamin D · 50 mcg

Omega-3 fats, vitamin D3, and branded MK-7 provide broad support for cardiovascular and skeletal health as people age. The active amounts are clearly useful, and the softgel supplies a suitable fat base for the vitamins.

The omega-3 is an ethyl ester and the label does not separate EPA from DHA, which weakens precision and form quality. MK-7 can counteract warfarin and other vitamin K antagonists, so people using those medicines need consistent vitamin K intake.

Study evidence
Omega-3 Supportive 56 studies
Vitamin K Supportive 27 studies
Skin Health
Skin Health
Impact
High effect
B+ Goal FitB+ Strength of SupportB- CoverageB- Formula Quality
Omega-3 · 2100 mg

A concentrated omega-three serving may support skin-barrier lipids and balanced inflammatory signaling. Vitamin D3 and branded vitamin K2 add a coherent bone-focused pairing.

The oil uses a less absorbable ethyl ester form and does not disclose EPA or DHA separately. The added vitamins broaden the formula but contribute little direct skin targeting.

Study evidence
Omega-3 Supportive 35 studies

Ingredients

IngredientAmount per serving
Calories
30 Calorie(s)
Total Fat
3 Gram(s)
Cholesterol
15 mg
Protein
1 Gram(s)
Vitamin D (Cholecalciferol)
 50 mcg
Total Omega-3 Fatty Acids Ethyl Esters
2100 mg
Vitamin K2 (Mena Q7)
 100 mcg
Adults 18–50
Report overview
Vitamin K (Mena Q7) · 100 mcg OverallScore90
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

Branded MenaQ7 supplies a clearly disclosed 100 mcg MK-7 dose with strong source quality. The omega-rich softgel supports absorption, while branded MK-7, vitamin D3, and omega fatty acids partly justify the high serving cost. The 100 mcg vitamin K amount can counteract warfarin and other vitamin K antagonist anticoagulants, so intake should remain consistent.

View ingredientView products
Omega-3 · 2100 mg OverallScore32
D- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The label clearly identifies the less bioavailable ethyl ester form and gives only a total omega-3 amount. Missing EPA and DHA amounts prevent verification of active concentration and cost per active gram. The supplied details also omit the oil source, antioxidant protection, and independent purity testing.

View ingredientView products
Loading alternative details
75 Performance

Vision Sharp Multi-Nutrient Eye Health

Irwin Naturals
<p>A stated 303 mg omega-3 amount plus lutein, zeaxanthin, bilberry, and antioxidant vitamins better supports a vision-centered goal. EPA and DHA are still missing, and ginkgo with fish oil may increase bleeding tendency with certain medicines.</p>
73 Performance

Wheatgrass Shots

Green Foods
<p>A clearly stated 164 mcg vitamin K amount provides more direct vitamin K coverage than many greens products. No omega-3 or vitamin D is supplied, so it is not a direct replacement and vitamin K intake should remain consistent with warfarin-type medicines.</p>
72 Performance

Postnatal Multi + DHA

Nature Made
<p>Vitamin D3, vitamin K, and 260 mg omega-3s are combined with broad postnatal micronutrients. EPA and DHA are not separated, and the iron-containing life-stage formula is appropriate only when postnatal coverage is needed.</p>
49 Budget

SuperGreens Antioxidant Natural Strawberry Lemonade Flavored

California Gold Nutrition Superfoods
<p>A 4 g greens blend and 70 mcg vitamin K come at a lower recurring cost than the omega formula. Hidden blend components and the absence of omega-3 and vitamin D make it suitable only for a narrower greens goal.</p>
68 Budget

Organic Wheat Grass

Amazing Grass
<p>Wheat grass supplies 80 mcg vitamin K, potassium, iron, and protein for less recurring cost. It contains no disclosed omega-3 or vitamin D, so it cannot replace the original for cardiovascular or bone-focused supplementation.</p>
79 Budget

Prenatal Multi + DHA

Nature Made
<p>A broad prenatal formula includes vitamin D3, vitamin K, and 260 mg fish oil at a much lower recurring cost. Omega-3 actives remain undisclosed, while the high iron and prenatal nutrient profile require an appropriate life-stage need.</p>
73 Value

Prenatal Multi + DHA 200mg

Nature Made
<p>Vitamin D3, vitamin K, and 260 mg omega-3s come with broad prenatal nutrients at a lower recurring cost. Incomplete fatty-acid detail and 27 mg iron make it a value option only for an appropriate prenatal need.</p>
48 Value

SuperGreens Antioxidant Natural Sweet Berry Flavored

California Gold Nutrition Superfoods
<p>A 4 g greens blend and 70 mcg vitamin K lower recurring cost for a food-based vitamin K goal. Missing blend details and the absence of omega-3 and vitamin D prevent it from replacing the original formula.</p>
72 Value

Wheatgrass Shots

Green Foods
<p>Wheat grass provides 164 mcg vitamin K plus modest vitamin C, potassium, iron, and protein at a lower recurring cost. It lacks omega-3 and vitamin D, while changing vitamin K intake may matter for people using warfarin-type medicines.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  2. The relationship between vitamin K and peripheral arterial disease.
    Vissers LET; Dalmeijer GW; Boer JMA; Verschuren WMM; van der Schouw YT; Beulens JWJ · Atherosclerosis · 2017
    Cohort study36,629 participantsCardiovascular Support forVitamin K
  3. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  4. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  5. Effects of Omega-3 Polyunsaturated Fatty Acid Supplementation on Bone Turnover in Older Women.
    Dong H; Hutchins-Wiese H; Kleppinger A; Annis K; Liva E; Lammi-Keefe C; Durham H; Feinn R; Kenny AM · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2015
    Randomized trial126 participantsBone Health forOmega-3
  6. Perilla seed oil improves bone health by inhibiting bone resorption in healthy Japanese adults: A 12-month, randomized, double-blind, placebo-controlled trial.
    Matsuzaki K; Hossain S; Wakatsuki H; Tanabe Y; Ohno M; Kato S; Shido O; Hashimoto M · Phytotherapy research : PTR · 2023
    Randomized trial52 participantsBone Health forOmega-3
  7. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
    Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Meta-analysis6,759 participants19 studies pooledBone Health forVitamin K
  8. Dietary intake of polyunsaturated fatty acids and risk of hip fracture in men and women.
    Virtanen JK; Mozaffarian D; Willett WC; Feskanich D · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013
    Cohort study122,354 participantsBone Health forOmega-3
  9. Interventions to Attenuate Cardiovascular Calcification Progression: A Systematic Review of Randomized Clinical Trials.
    Murali S; Smith ER; Tiong MK; Tan SJ; Toussaint ND · Journal of the American Heart Association · 2024
    Systematic review9,901 participants49 studies pooledCardiovascular Support forVitamin K
  10. Fatty acid consumption and risk of fracture in the Women's Health Initiative.
    Orchard TS; Cauley JA; Frank GC; Neuhouser ML; Robinson JG; Snetselaar L; Tylavsky F; Wactawski-Wende J; Young AM; Lu B; Jackson RD · The American journal of clinical nutrition · 2010
    Cohort study137,486 participantsBone Health forOmega-3
  11. Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease.
    van den Heuvel EG; van Schoor NM; Lips P; Magdeleyns EJ; Deeg DJ; Vermeer C; den Heijer M · Maturitas · 2014
    Cohort study577 participantsCardiovascular Support forVitamin K
  12. Effect of omega-3 fatty acids on the telomere length: A mini meta-analysis of clinical trials.
    Ali S; Scapagnini G; Davinelli S · Biomolecular concepts · 2022
    Meta-analysis337 participants5 studies pooledAnti-Aging forOmega-3
  13. Omega-3 supplementation and stress reactivity of cellular aging biomarkers: an ancillary substudy of a randomized, controlled trial in midlife adults.
    Madison AA; Belury MA; Andridge R; Renna ME; Rosie Shrout M; Malarkey WB; Lin J; Epel ES; Kiecolt-Glaser JK · Molecular psychiatry · 2022
    Randomized trial138 participantsAnti-Aging forOmega-3
  14. Omega-3 Polyunsaturated Fatty Acids and Cognitive Decline in Adults with Non-Dementia or Mild Cognitive Impairment: An Overview of Systematic Reviews.
    Barros MI; Brandão T; Irving SC; Alves P; Gomes F; Correia M · Nutrients · 2025
    Meta-analysis26,881 participants9 studies pooledAnti-Aging forOmega-3
  15. Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease.
    Farzaneh-Far R; Lin J; Epel ES; Harris WS; Blackburn EH; Whooley MA · JAMA · 2010
    Cohort study608 participantsAnti-Aging forOmega-3
  16. Long-chain omega-3 fatty acids improve brain function and structure in older adults.
    Witte AV; Kerti L; Hermannstädter HM; Fiebach JB; Schreiber SJ; Schuchardt JP; Hahn A; Flöel A · Cerebral cortex (New York, N.Y. : 1991) · 2015
    Randomized trial65 participantsAnti-Aging forOmega-3
  17. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  18. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  19. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  20. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  21. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  22. Habitual use of fish oil supplements, genetic predisposition, and risk of fractures: a large population-based study.
    Mei Z; Chen GC; Hu J; Lin C; Sun Z; Liu C; Geng X; Yuan C; Qi Q; Zheng Y · The American journal of clinical nutrition · 2021
    Cohort study492,713 participantsBone Health forOmega-3
  23. An increase in dietary n-3 fatty acids decreases a marker of bone resorption in humans.
    Griel AE; Kris-Etherton PM; Hilpert KF; Zhao G; West SG; Corwin RL · Nutrition journal · 2007
    Randomized trial23 participantsBone Health forOmega-3
  24. The Relationship Between Omega-3, Omega-6 and Total Polyunsaturated Fat and Musculoskeletal Health and Functional Status in Adults: A Systematic Review and Meta-analysis of RCTs.
    Abdelhamid A; Hooper L; Sivakaran R; Hayhoe RPG; Welch A; PUFAH Group · Calcified tissue international · 2020
    Meta-analysis7,288 participants28 studies pooledBone Health forOmega-3
  25. Dietary intake of fish, n-3 polyunsaturated fatty acids and risk of hip fracture: A systematic review and meta-analysis on observational studies.
    Sadeghi O; Djafarian K; Ghorabi S; Khodadost M; Nasiri M; Shab-Bidar S · Critical reviews in food science and nutrition · 2019
    Meta-analysis292,657 participants10 studies pooledBone Health forOmega-3
  26. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  27. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  28. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  29. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  30. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  31. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  32. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  33. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  34. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  35. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support forVitamin D
  36. A Randomized Trial of Vitamin D Supplementation on Vascular Function in CKD.
    Kumar V; Yadav AK; Lal A; Kumar V; Singhal M; Billot L; Gupta KL; Banerjee D; Jha V · Journal of the American Society of Nephrology : JASN · 2017
    Randomized trial120 participantsCardiovascular Support forVitamin D
  37. Randomized, placebo-controlled, double-blind clinical trial on the contributions of vitamin D in the control of cardiovascular risk factors, depressive symptoms and suicide risk.
    Porto C; Petribu K; Barbosa N; Magalhães R; Lira C; Porto AB; Markman-Filho B; Lordsleem A; Calado E; Magalhães J; Sougey E; Silva T; Junio A; Bandeira F; Leão R · American heart journal plus : cardiology research and practice · 2025
    Randomized trial224 participantsCardiovascular Support forVitamin D
  38. Dose responses of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency: A placebo controlled randomized trial.
    Raed A; Bhagatwala J; Zhu H; Pollock NK; Parikh SJ; Huang Y; Havens R; Kotak I; Guo DH; Dong Y · PloS one · 2017
    Randomized trial70 participantsCardiovascular Support forVitamin D
  39. Paricalcitol and endothelial function in chronic kidney disease trial.
    Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
    Randomized trial88 participantsCardiovascular Support forVitamin D
  40. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  41. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  42. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  43. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  44. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  45. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  46. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  47. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  48. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K
  49. Supplementation of fish oil and olive oil in patients with rheumatoid arthritis.
    Berbert AA; Kondo CR; Almendra CL; Matsuo T; Dichi I · Nutrition (Burbank, Los Angeles County, Calif.) · 2005
    Randomized trial43 participantsJoint Health forOmega-3
  50. Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial.
    Stonehouse W; Benassi-Evans B; Bednarz J; Vincent AD; Hall S; Hill CL · The American journal of clinical nutrition · 2022
    Randomized trial235 participantsJoint Health forOmega-3
  51. Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials.
    Wang W; Xu Y; Zhou J; Zang Y · Clinical rheumatology · 2024
    Meta-analysis1,018 participants18 studies pooledJoint Health forOmega-3
  52. Impact of type and dose of oral polyunsaturated fatty acid supplementation on disease activity in inflammatory rheumatic diseases: a systematic literature review and meta-analysis.
    Sigaux J; Mathieu S; Nguyen Y; Sanchez P; Letarouilly JG; Soubrier M; Czernichow S; Flipo RM; Sellam J; Daïen C · Arthritis research & therapy · 2022
    Meta-analysis1,420 participants30 studies pooledJoint Health forOmega-3
  53. A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain.
    Goldberg RJ; Katz J · Pain · 2007
    Meta-analysis17 studies pooledJoint Health forOmega-3
  54. Low vitamin K status is associated with osteoarthritis in the hand and knee.
    Neogi T; Booth SL; Zhang YQ; Jacques PF; Terkeltaub R; Aliabadi P; Felson DT · Arthritis and rheumatism · 2006
    Cohort study672 participantsJoint Health forVitamin K
  55. Associations Between Dietary Intake of Vitamin K and Changes in Symptomatic and Structural Changes in Patients With Knee Osteoarthritis.
    Liao Z; Chang J; Zhu Z; Han W; Meng T; Zheng S; Tu L; Antony B; Winzenberg T; Wluka AE; Cicuttini F; Ding C · Arthritis care & research · 2023
    Cohort study259 participantsJoint Health forVitamin K
  56. Association of low dietary vitamin K intake with radiographic knee osteoarthritis in the Japanese elderly population: dietary survey in a population-based cohort of the ROAD study.
    Oka H; Akune T; Muraki S; En-yo Y; Yoshida M; Saika A; Sasaki S; Nakamura K; Kawaguchi H; Yoshimura N · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2010
    Cross-sectional study719 participantsJoint Health forVitamin K
  57. The Relationship between Vitamin K and Osteoarthritis: A Review of Current Evidence.
    Chin KY · Nutrients · 2021
    Narrative reviewJoint Health forVitamin K
  58. Vitamin K deficiency is associated with incident knee osteoarthritis.
    Misra D; Booth SL; Tolstykh I; Felson DT; Nevitt MC; Lewis CE; Torner J; Neogi T · The American journal of medicine · 2013
    Cohort study1,180 participantsJoint Health forVitamin K
  59. Effects of omega-3 supplementation on glucose and lipid metabolism in patients with gestational diabetes: A meta-analysis of randomized controlled trials.
    Liu W; Gao M; Yang S; Sun C; Bi Y; Li Y; Wang J; Yuan X · Journal of diabetes and its complications · 2023
    Meta-analysis331 participants6 studies pooledMetabolism Boost forOmega-3
  60. Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism.
    Green CJ; Pramfalk C; Charlton CA; Gunn PJ; Cornfield T; Pavlides M; Karpe F; Hodson L · BMJ open diabetes research & care · 2021
    Randomized trial38 participantsMetabolism Boost forOmega-3
  61. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsMetabolism Boost Skin Health forOmega-3
  62. The Effects of Flaxseed Oil Omega-3 Fatty Acids Supplementation on Metabolic Status of Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Mirmasoumi G; Fazilati M; Foroozanfard F; Vahedpoor Z; Mahmoodi S; Taghizadeh M; Esfeh NK; Mohseni M; Karbassizadeh H; Asemi Z · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2018
    Randomized trial60 participantsMetabolism Boost forOmega-3
  63. A combination of omega-3 and plant sterols regulate glucose and lipid metabolism in individuals with impaired glucose regulation: a randomized and controlled clinical trial.
    Wang JF; Zhang HM; Li YY; Xia S; Wei Y; Yang L; Wang D; Ye JJ; Li HX; Yuan J; Pan RR · Lipids in health and disease · 2019
    Randomized trial200 participantsMetabolism Boost forOmega-3
  64. Effects of vitamin D supplementation on insulin resistance and lipid metabolic profiles in women with gestational diabetes mellitus: A randomized controlled trial.
    Duan Y; Zhang S; Ma X; Li L; Jia K · African journal of reproductive health · 2026
    Randomized trial120 participantsMetabolism Boost forVitamin D
  65. Vitamin D3 improves glucose metabolism and attenuates inflammation in prediabetic human and mice.
    Zhang Y; Ni P; Miao Y; Chen H; Tang L; Song H; Li W; Li X · The Journal of nutritional biochemistry · 2024
    Randomized trialMetabolism Boost forVitamin D
  66. Effects of vitamin D and calcium supplementation on pancreatic β cell function, insulin sensitivity, and glycemia in adults at high risk of diabetes: the Calcium and Vitamin D for Diabetes Mellitus (CaDDM) randomized controlled trial.
    Mitri J; Dawson-Hughes B; Hu FB; Pittas AG · The American journal of clinical nutrition · 2011
    Randomized trial92 participantsMetabolism Boost forVitamin D
  67. The Effects of Vitamin D Supplementation on Glycemic Control, Lipid Profiles and C-Reactive Protein Among Patients with Cardiovascular Disease: a Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Ostadmohammadi V; Milajerdi A; Ghayour-Mobarhan M; Ferns G; Taghizadeh M; Badehnoosh B; Mirzaei H; Asemi Z · Current pharmaceutical design · 2020
    Meta-analysis630 participants8 studies pooledMetabolism Boost forVitamin D
  68. The Effect of Improved Serum 25-Hydroxyvitamin D Status on Glycemic Control in Diabetic Patients: A Meta-Analysis.
    Mirhosseini N; Vatanparast H; Mazidi M; Kimball SM · The Journal of clinical endocrinology and metabolism · 2017
    Meta-analysis1,528 participants24 studies pooledMetabolism Boost forVitamin D
  69. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  70. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  71. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  72. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3