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Magnesium Malate 400

4.8
★ ★ ★ ★ ★
(37199 ratings)
Magnesium 400 mg
Product Image
Score92
A high-dose magnesium malate formula offers good absorption and strong value. Tablet size and limited dose flexibility may reduce convenience.
How scoring works
Tablet
Quantity:90 Tablet(s) • (45 servings)
Goals:
General Health
Heart Health
Energy
Cardiovascular Support
Bone Health
Stress Relief
Fitness
Testosterone Support
Digestive Health

Score 92

A high-dose magnesium malate formula offers good absorption and strong value. Tablet size and limited dose flexibility may reduce convenience.
How scoring works
$17.39($0.38 per serving)
Vitacost
$ 17.39
iHerb
$ 17.39
Pure Formulas
$ 17.39
Vitacost
$ 17.39
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Analysis

Two tablets provide 400 mg magnesium as malate. Malate is an organic form with good absorption potential and direct relevance to energy metabolism through its malic acid component.

The dose is well aligned with substantial magnesium supplementation and supports broad cardiovascular, muscle, and energy-related functions. A single form keeps the label clear, although there is no separate cofactor or flexible split-dose guidance in the supplied data.

Forty-five servings and a low serving cost make the formula economical for its form. People who find tablets difficult to swallow or who need less than 400 mg may prefer capsules or powder.

Who is it for
  • Adults comfortable with tablets
  • Users seeking broad magnesium support
  • People who can account for dietary and supplemental magnesium
Best for
  • Routine magnesium supplementation
  • Muscle, nerve, and energy support
  • Tablets dosing

Pros

  • Uses magnesium malate
  • Clearly supplies 400 mg magnesium
  • Good value per serving
  • Simple single-form label

Cons

  • High amount may exceed some users needs
  • Only 45 servings
  • Tablets may be hard to swallow
  • No added cofactor

Warnings

  • The 400 mg magnesium serving can cause loose stools or stomach discomfort
  • Impaired kidney function increases concern about magnesium accumulation
  • Magnesium should be separated from tetracycline or quinolone antibiotics and bisphosphonates

Nutrient quality

94 Highest impact

The elemental magnesium amount is meaningful for supplementation. The amount is substantial and may challenge digestive tolerance.

Ingredient transparency

86 Highest impact

The active magnesium amount is specifically disclosed. The serving count is supplied, but complete use directions are missing.

Customer satisfaction

93 Highest impact

The large review count makes the aggregate rating highly reliable. Specific experiences are absent, but the strong aggregate rating is broadly consistent with satisfaction.

Value for money

96 Highest impact

The supply provides excellent value per meaningful serving. The magnesium form and dose strongly support the formula’s qualitative value.

Report analysis

Goals

General Health
General Health
Impact
Highest effect
A+ Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Magnesium · 400 mg

Magnesium malate provides a well-absorbed form of an essential mineral involved in energy metabolism, muscle function, and nerve signaling. The amount is substantial and clearly identified.

The single-mineral design gives strong depth without claiming broad nutrient coverage. A 400 mg supplemental serving may still cause loose stools or abdominal discomfort in sensitive users, even though malate is generally better tolerated than oxide.

Study evidence
Magnesium Supportive 114 studies
Heart Health
Heart Health
Impact
Highest effect
B+ Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Magnesium · 400 mg

The 400 mg magnesium malate amount supports vascular tone, heart rhythm, and normal muscle function. Malate is a useful organic form, although cardiovascular benefits are most likely when magnesium status is low.

The elemental amount and form are clearly disclosed across a two-tablet serving. Supplemental magnesium at this amount may cause loose stools or abdominal discomfort in sensitive users.

Study evidence
Magnesium Supportive 158 studies
Energy
Energy
Impact
Highest effect
A- Goal FitA Strength of SupportC CoverageA+ Formula Quality
Magnesium · 400 mg

The 400 mg magnesium amount supports ATP-related enzymes, nerve signaling, and muscle function. Energy benefits are most likely when magnesium intake is inadequate rather than as immediate stimulation.

Malate provides a clearly named organic form with good absorption potential. The 400 mg supplemental amount may cause loose stools or abdominal cramping in sensitive users.

Study evidence
Magnesium Supportive 4 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
B+ Goal FitA- Strength of SupportD+ CoverageA Formula Quality
Magnesium · 400 mg

Magnesium supports vascular relaxation, blood-pressure regulation, and normal heart rhythm. Magnesium malate offers a well-absorbed form, making the product relevant when intake is low.

The 400 mg amount is substantial but exceeds the usual supplemental upper limit and may cause diarrhea or abdominal discomfort. The focused design provides strong magnesium depth while leaving lipid, nitric-oxide, and cardiac-energy pathways uncovered.

Study evidence
Magnesium Supportive 123 studies
Bone Health
Bone Health
Impact
Highest effect
B- Goal FitA+ Strength of SupportC- CoverageA Formula Quality
Magnesium · 400 mg

Magnesium is a structural bone mineral and helps activate vitamin D. The single-mineral focus does not provide calcium, vitamin K, or collagen support.

The 400 mg elemental amount is clearly stated, and malate is a clearly named and reasonably absorbable form. Higher supplemental magnesium may cause diarrhea or abdominal discomfort in sensitive users.

Study evidence
Magnesium Supportive 48 studies
Stress Relief
Stress Relief
Impact
High effect
B- Goal FitA- Strength of SupportC- CoverageA Formula Quality
Magnesium · 400 mg

A substantial magnesium serving provides relevant nervous-system support and may help relaxation when intake is inadequate. Evidence is stronger for correcting low magnesium status than for producing a large stress reduction in every user.

The magnesium malate form is clearly identified at 400 mg. Malate offers a well-absorbed form but is more associated with energy metabolism than a uniquely calming effect. The focused mineral support does not address cortisol regulation or provide a separate calming neurotransmitter active.

Study evidence
Magnesium Supportive 13 studies

Ingredients

IngredientAmount per serving
Total Carbohydrates
1 Gram(s)
Magnesium (Magnesium Malate)
 400 mg
Gluten Free Adults 18–50 Vegan Vegetarian
Report overview
Magnesium (Magnesium Malate) · 400 mg OverallScore84
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value
+1

Magnesium malate provides a highly bioavailable organic form. The 400 mg elemental amount is well aligned with the therapeutic range. A low serving cost makes the clean single-form formula especially economical.

View ingredientView products
Loading alternative details
82 Performance

Albion DiMagnesium Malate

Swanson Ultra
A more purposeful active profile is better aligned with the original’s main use because albion dimagnesium malate supplies a well-defined chelated form at a substantial amount. The focused formula supports broad magnesium needs and offers fair value despite a higher serving cost than basic forms.
82 Performance

Advanced Magnesium Complex

AOR Advanced Orthomolecular Research Advanced
A more purposeful active profile is better aligned with the original’s main use because several absorbable magnesium forms and a substantial glycine yield make this a well-designed foundational mineral formula. The label does not separate how much elemental magnesium comes from each form, and several carriers overlap in purpose.
88 Performance

Magnesium Bisglycinate Powder

NOW
A more purposeful active profile is better aligned with the original’s main use because magnesium bisglycinate supplies a well-absorbed form at a practical, moderate amount. The pure powder is adjustable, clearly labeled, and inexpensive, supporting strong routine value.
79 Budget

Target-Mins Magnesium Caps With Silica 300 mg

Country Life
Lower serving cost makes it the more economical option, while the mineral blend combines useful magnesium forms with oxide and a substantial horsetail-derived silica amount. The elemental total is clear, but the split among magnesium forms and horsetail standardization are not.
83 Budget

Magnesium Citrate Pure Powder

Best Naturals
Lower serving cost makes it the more economical option, while a well-aligned amount of magnesium citrate delivers useful absorption in a focused powder. The simple formula and very low serving cost provide strong value, with digestive tolerance as the main practical uncertainty.
91 Budget

Krebs Magnesium Potassium Complex

Nature's Way
Lower serving cost makes it the more economical option, while magnesium lysinate and malate provide favorable forms at a useful amount, with a modest potassium contribution. The focused formula offers excellent serving value.
84 Value

Potassium + Magnesium

Nutricost
Ingredient quality and serving value are better balanced here because a meaningful magnesium citrate amount anchors a simple two-mineral electrolyte formula. Potassium is modest, but the focused design and very low serving cost support excellent everyday value.
85 Value

Cal/Mag 500 mg/250 mg

NaturesPlus
Ingredient quality and serving value are better balanced here because chelated calcium and magnesium provide a focused, balanced mineral formula with strong form quality. A simple one-serving format and economical cost make it one of the better value profiles in this set.
83 Value

Magnesium Citrate 200 mg

Best Naturals
Ingredient quality and serving value are better balanced here because a substantial amount of magnesium citrate combines useful absorption with a focused single-active design. Digestive sensitivity is the main trade-off, while the low serving cost supports strong practical value.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  2. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  3. The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
    van der Schoot A; Creedon A; Whelan K; Dimidi E · Neurogastroenterology and motility · 2023
    Meta-analysis787 participants8 studies pooledDigestive Health forMagnesium
  4. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  5. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  6. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  7. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  8. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  9. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  10. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  11. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  12. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  13. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  14. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  15. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  16. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  17. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  18. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  19. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  20. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy Fitness forMagnesium
  21. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  22. Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort.
    Welch AA; Skinner J; Hickson M · Nutrients · 2018
    Cross-sectional study156,575 participantsFitness forMagnesium
  23. Dietary Magnesium Is Positively Associated With Skeletal Muscle Power and Indices of Muscle Mass and May Attenuate the Association Between Circulating C-Reactive Protein and Muscle Mass in Women.
    Welch AA; Kelaiditi E; Jennings A; Steves CJ; Spector TD; MacGregor A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
    Cross-sectional study2,570 participantsFitness forMagnesium
  24. Nutritional intake as a determinant of high-speed resistance and multicomponent training efficacy on strength in older women at risk of sarcopenia. A randomized clinical trial.
    Polo-Ferrero L; Recio-Rodriguez JI; González-Manzano S; Martín-Vallejo J; Barbero-Iglesias FJ; Montero-Errasquín B; Cruz-Jentoft AJ; Méndez-Sánchez R · Clinical nutrition (Edinburgh, Scotland) · 2025
    Randomized trial80 participantsFitness forMagnesium
  25. Minerals and Sarcopenia in Older Adults: An Updated Systematic Review.
    van Dronkelaar C; Fultinga M; Hummel M; Kruizenga H; Weijs PJM; Tieland M · Journal of the American Medical Directors Association · 2023
    Systematic review45 studies pooledFitness forMagnesium
  26. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  27. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  28. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  29. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  30. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  31. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  32. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  33. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  34. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  35. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  36. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  37. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  38. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  39. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  40. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  41. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  42. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  43. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium