Methyl-Guard Plus
Thorne
Score 88
This supplement provides a targeted blend of activated B vitamins and TMG, designed to support crucial methylation processes in the body for overall metabolic and cellular health.
Score 88
This supplement provides a targeted blend of activated B vitamins and TMG, designed to support crucial methylation processes in the body for overall metabolic and cellular health.
Analysis
Methyl-Guard Plus is designed to support methylation, a fundamental process involved in many bodily functions including detoxification, energy production, and neurotransmitter synthesis. It features activated forms of key B vitamins like riboflavin (as Riboflavin 5'-Phosphate Sodium), Vitamin B6 (as Pyridoxal 5-Phosphate), Vitamin B12 (as Methylcobalamin), and Folate (as L-5-MTHF), which means the body does not need to convert them into their active forms before use.
Beyond the activated B vitamins, the product also includes Betaine Anhydrous (Trimethylglycine or TMG). TMG works alongside these B vitamins to contribute to healthy homocysteine levels, which is important for cardiovascular well-being. This combination makes it suitable for individuals specifically looking to support their methylation cycle or those who may have genetic variations that affect their ability to process standard B vitamin forms.
This supplement is often used by those who want to support overall cellular health and metabolic efficiency. The specific forms of nutrients may provide more direct support for various biochemical reactions. It's a targeted formula for methylation support rather than a general multivitamin.
Pros
- Features activated forms of B vitamins for direct usability.
- Includes Trimethylglycine (TMG) to work alongside B vitamins in methylation.
- Combines key nutrients often recommended for homocysteine balance.
- Provides specific support for individuals with methylation pathway needs.
Cons
- Higher cost per serving compared to basic B vitamin supplements.
- The specific B vitamin forms and dosages might be more than some individuals need.
- Not a broad-spectrum multivitamin; focuses primarily on methylation support.
Warnings
- Individuals sensitive to B vitamins, especially methyl forms, might experience increased energy or mild jitters; consider starting with a lower dose if possible.
- High doses of certain B vitamins can mask deficiencies of other B vitamins.
- Always discuss new supplements with a healthcare professional, especially if you have existing health conditions or are taking medications.
$62.00($2.06 per serving)
 Pure Formulas | $ 62.00 | |
 Vitacost | $ 62.00 | |
 iHerb | $ 62.00 |
Goals
Impact
Highest effect
Methylation is a critical pathway in the liver's detoxification processes, helping to process and eliminate toxins. The activated B vitamins and TMG in this product directly support these biochemical reactions, contributing to the body's natural detoxification efforts.
Impact
Highest effect
Methylation is vital for various brain functions, including myelin formation, neurotransmitter production, and cognitive processes. The active B vitamins and TMG in this formula can help support optimal neurological function, contributing to brain health.
Impact
Highest effect
The ingredients in this product, particularly folate, B12, B6, and TMG, are recognized for their role in regulating homocysteine levels. Healthy homocysteine metabolism is an important factor in maintaining cardiovascular well-being.
Impact
Highest effect
The activated B vitamins and TMG in this formula are crucial for the methylation cycle, which helps convert homocysteine into other beneficial molecules. Maintaining healthy homocysteine levels is an important aspect of overall cardiovascular health.
Impact
Highest effect
Cognitive function relies heavily on efficient brain metabolism and neurotransmitter activity, both of which are supported by healthy methylation pathways. The activated B vitamins and TMG can help maintain these critical processes for cognitive sharpness.
Impact
Highest effect
Methylation plays a key role in the synthesis of neurotransmitters like serotonin, dopamine, and norepinephrine, which are essential for mood regulation. By providing crucial methyl donors and cofactors, this supplement can contribute to balanced neurotransmitter production, potentially aiding mood support.
Impact
Highest effect
B vitamins are indispensable for the conversion of food into cellular energy. By providing activated forms, this supplement helps ensure the body has the necessary cofactors for efficient energy production, which can contribute to overall energy levels.
Impact
High effect
B vitamins are fundamental cofactors in numerous metabolic pathways involved in energy production and nutrient utilization. By supplying activated B vitamins, this supplement helps ensure these metabolic processes can function efficiently, potentially contributing to a 'boost' in metabolic efficiency.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Riboflavin | 90 mg |
Vitamin B6 | 45 mg |
Folate | 5 mcg DFE |
Vitamin B12 | 3 mg |
Betaine Anhydrous | 1.8 Gram(s) |
Vitamin B6 90
The product uses Pyridoxal 5-Phosphate (P5P), which is the active, coenzymated form of Vitamin B6. This form is readily usable by the body for its various functions without requiring conversion, making it a high-quality choice for B6 supplementation.
Riboflavin 90
Riboflavin 5'-Phosphate Sodium is the active form of Riboflavin (Vitamin B2). Providing Riboflavin in its coenzymated form means it's immediately available for metabolic processes, ensuring optimal utilization compared to standard riboflavin.
Alternative products
90 Value 
Pyridoxal 5'-Phosphate Caps 100 mg
Life Extension
With a slightly higher analysis score and a significantly higher dose of active B6 (P-5-P) than your current product, this alternative provides excellent support for cognitive function and metabolism at a much more favorable cost per serving, representing great value.
88 Value 
Riboflavin 5'-Phosphate
Thorne
This product from your current brand offers an active form of Riboflavin (B2) with the same high analysis score as your current complex, but at a considerably lower price per serving. It's a great value if your main goal is to specifically support energy and detoxification pathways with active B2.
88 Value 
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
This alternative matches your current product's analysis score and provides an active form of Vitamin B6 (P-5-P) at a very low price per serving. It's a straightforward and cost-effective way to get targeted B6 support for mood and brain health.
92 Performance 
Riboflavin 400 mg
Seeking Health
This alternative provides a substantially higher concentration of Riboflavin, including its active form, compared to your current supplement. If you're seeking more potent support for energy production, detoxification processes, or specific metabolic pathways where Riboflavin plays a crucial role, this could be a more effective choice.
88 Performance 
B6 Complex
Pure Encapsulations
While named for B6, this is a highly comprehensive B-complex that offers a broader and often higher potency spectrum of active B vitamins than your current product. It includes active Riboflavin (Riboflavin 5-Phosphate), a significantly higher dose of active B6 (P-5-P), active Folate (Metafolin), and multiple active forms of Vitamin B12, providing robust support for overall methylation, mood, cognitive function, and energy.
90 Performance
Pyridoxal 5'-Phosphate Caps 100 mg
Life Extension
This product offers a higher and more concentrated dose of active Vitamin B6 (P-5-P) than your current supplement. If enhancing brain health, stabilizing mood, or supporting enzyme functions dependent on B6 is a primary focus, this option can provide a more powerful impact.
88 Budget 
P-5-P 100 mg
Nutricost
This alternative offers a higher dose of active Vitamin B6 (P-5-P) compared to your current product, which can be particularly helpful for brain health, mood support, and metabolism. It provides excellent targeted B6 support at a significantly lower cost per serving.
78 Budget 
B-100
NOW
If you're looking for a more generalized B vitamin boost at a much more accessible price per serving, this complex includes Riboflavin and Folate, along with other B vitamins. While it doesn't use the active forms of B6 and B12 found in your current product, it supports overall energy and metabolic functions broadly.
88 Budget 
BioCoenzymated Pyridoxal 5'-Phosphate 50 mg
Natural Factors
This product focuses on providing the active form of Vitamin B6 (P-5-P) at a very budget-friendly price per serving. It's a great choice if your primary goal is to support mental focus and cognitive functions directly related to active B6.
88 Budget
Riboflavin 5'-Phosphate
Thorne
For targeted support of Riboflavin, this product from the same brand delivers the active form (Riboflavin 5'-Phosphate). It's a much cheaper option per serving if your main interest is boosting energy pathways and supporting detoxification via active B2.
88 Value
P-5-P 100 mg
Nutricost
This product matches the analysis score of your current supplement while delivering a higher dose of active Vitamin B6 (P-5-P) at a remarkably low price per serving. It offers exceptional value for those seeking strong, targeted B6 support for brain function and energy without a premium price.
90 Value
Pyridoxal 5'-Phosphate Caps 100 mg
Life Extension
With a slightly higher analysis score and a significantly higher dose of active B6 (P-5-P) than your current product, this alternative provides excellent support for cognitive function and metabolism at a much more favorable cost per serving, representing great value.
88 Value
Riboflavin 5'-Phosphate
Thorne
This product from your current brand offers an active form of Riboflavin (B2) with the same high analysis score as your current complex, but at a considerably lower price per serving. It's a great value if your main goal is to specifically support energy and detoxification pathways with active B2.
88 Value
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
This alternative matches your current product's analysis score and provides an active form of Vitamin B6 (P-5-P) at a very low price per serving. It's a straightforward and cost-effective way to get targeted B6 support for mood and brain health.
92 Performance
Riboflavin 400 mg
Seeking Health
This alternative provides a substantially higher concentration of Riboflavin, including its active form, compared to your current supplement. If you're seeking more potent support for energy production, detoxification processes, or specific metabolic pathways where Riboflavin plays a crucial role, this could be a more effective choice.
88 Performance
B6 Complex
Pure Encapsulations
While named for B6, this is a highly comprehensive B-complex that offers a broader and often higher potency spectrum of active B vitamins than your current product. It includes active Riboflavin (Riboflavin 5-Phosphate), a significantly higher dose of active B6 (P-5-P), active Folate (Metafolin), and multiple active forms of Vitamin B12, providing robust support for overall methylation, mood, cognitive function, and energy.
90 Performance
Pyridoxal 5'-Phosphate Caps 100 mg
Life Extension
This product offers a higher and more concentrated dose of active Vitamin B6 (P-5-P) than your current supplement. If enhancing brain health, stabilizing mood, or supporting enzyme functions dependent on B6 is a primary focus, this option can provide a more powerful impact.