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Testosterone UP

Irwin Naturals
4.6
★ ★ ★ ★ ★
(389 ratings)
Zinc 30 mg
Stinging Nettle 300 mg
Copper 2 mg
Protein 1 Gram(s)
Product Image
Score76
A coherent testosterone formula led by zinc, nettle, and branded tongkat ali, with weaker secondary ingredients and a high serving burden.
How scoring works
Quantity:120 Softgel(s) • (40 servings)
Goals:
Testosterone Support
General Health

Score 76

A coherent testosterone formula led by zinc, nettle, and branded tongkat ali, with weaker secondary ingredients and a high serving burden.
How scoring works
$59.99($1.49 per serving)
iHerb
$ 59.99
Vitacost
$ 59.99
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Analysis

Testosterone support is the most credible use. A robust zinc amount, nettle root, branded tongkat ali, pumpkin-seed oil, plant sterols, and ginseng address mineral, vitality, and free-hormone pathways.

Copper appropriately balances the zinc, and oil-based softgels suit the lipophilic components. Nettle and ginseng lack active-marker details, while chrysin and gamma-oryzanol add less convincing depth than the core ingredients.

The blend fits adult men seeking a multi-pathway hormone-support product rather than a sports-performance or general-health supplement. It is poorly matched to vision, bone, immunity, or hair goals, particularly for people concerned about androgen-sensitive hair thinning.

Who is it for
  • Adult men seeking multi-ingredient testosterone support
  • Users who value zinc balanced with copper
  • People not relying on it as a dedicated fitness product
Best for
  • Testosterone-oriented mineral and botanical coverage
  • Nettle and tongkat ali support
  • Oil-based softgel delivery

Pros

  • Uses well-absorbed zinc methionine
  • Includes copper in a sensible balance
  • Meaningful nettle root amount
  • Uses branded LJ100 tongkat ali

Cons

  • Requires three softgels per serving
  • Nettle and ginseng lack standardization
  • Chrysin has weak practical relevance
  • High serving cost

Warnings

  • The 30 mg zinc serving should not be stacked long term with other high-zinc products, even though 2 mg copper provides some balance.
  • Asian ginseng may affect blood glucose and can interact with anticoagulant or antiplatelet medicines.
  • BioPerine can alter absorption of some medicines, so drugs with a narrow therapeutic range should not be taken casually alongside the formula.
  • Ingredients intended to support androgen activity may be a poor fit for people concerned about androgen-sensitive hair thinning.

Nutrient quality

78 High impact

Bioavailable zinc and copper forms, a meaningful nettle dose, and branded tongkat ali support the primary goal. High zinc and several incompletely standardized botanicals reduce suitability for broad, unsupervised use.

Ingredient transparency

80 Highest impact

Specific amounts are listed for every active, and no proprietary blend hides the doses. Extract standardization, complete directions, and inactive softgel ingredients are not fully supplied.

Customer satisfaction

68 High impact

The aggregate rating is favorable and supported by a meaningful number of reviews. No specific review comments were supplied, so repeated complaints and purpose-related experiences cannot be verified.

Value for money

75 High impact

The broad, clearly dosed active profile provides reasonable value for targeted use. High zinc and uneven botanical evidence keep it from comparing as strongly as more focused formulas.

Report analysis

Goals

Testosterone Support
Testosterone Support
Impact
Highest effect
B+ Goal FitB+ Strength of SupportA- CoverageB- Formula Quality
Zinc · 30 mg

Zinc methionine, nettle root, branded Tongkat Ali, pumpkin-seed oil, plant sterols, and ginseng create strong production and free-hormone pathway coverage. Zinc, nettle, and Tongkat Ali are supplied at useful amounts, though nettle lacks standardization and evidence for chrysin and gamma-oryzanol is weak.

Copper appropriately balances the 30 mg zinc amount, and the oil-based softgel suits lipophilic ingredients. The core is coherent, but chrysin and several secondary additions provide more label appeal than proven hormonal contribution.

Study evidence
Zinc Disputed 7 studies
General Health
General Health
Impact
High effect
C- Goal FitB- Strength of SupportD+ CoverageB Formula Quality
Zinc · 30 mg

Well-absorbed zinc with balancing copper supports one important foundational mineral need. The remaining formula centers on hormone and prostate-related ingredients rather than broad daily nutrition.

Several botanicals and phytosterols have limited direct relevance to general health, and the zinc amount is relatively high for long-term use. The product is better suited to a specific men’s health objective than to comprehensive wellness support.

Study evidence
Zinc Supportive 60 studies
Hair Health
Hair Health
Impact
Moderate effect
D+ Goal FitB Strength of SupportC- CoverageD Formula Quality
Zinc · 30 mg

Chelated zinc, copper, nettle, pumpkin seed oil, and plant sterols offer some nutritional and hormonal relevance to hair. The testosterone-focused purpose creates uncertainty for people concerned about androgen-related thinning.

Zinc and copper are well supplied in useful forms, but the formula lacks a clearly standardized hair-loss active. Ingredients intended to support androgen activity may work against the goal in people with androgen-sensitive follicles.

Study evidence
Copper Adverse 4 studies
Zinc Supportive 22 studies
Fitness
Fitness
Impact
Moderate effect
D Goal FitC Strength of SupportC- CoverageC Formula Quality

Ginseng and Tongkat Ali may support vitality in some users, but the formula lacks creatine, citrulline, beta-alanine, or another established sports active. Zinc is substantial and uses a favorable methionine form.

The testosterone-oriented botanical evidence is mixed, and several ingredients have no clear effect on power, endurance, or recovery. The formula is more relevant to men’s health than to a defined training outcome.

Study evidence
Zinc Supportive 7 studies
Skin Health
Skin Health
Impact
Moderate effect
C- Goal FitB- Strength of SupportD CoverageD- Formula Quality
Zinc · 30 mgCopper · 2 mg

Zinc and copper support repair and collagen-crosslinking enzymes, but the testosterone formula is only tangentially related to skin. Zinc reaches 30 mg and copper reaches 2 mg, providing substantial mineral support.

The formula addresses mineral-dependent repair and collagen-crosslinking cofactors. Mineral depth is reasonable, but structural, hydration, and antioxidant pathways are largely absent.

Study evidence
Copper Supportive 16 studies
Zinc Supportive 66 studies
Vision Support
Vision Support
Impact
Moderate effect
D- Goal FitB- Strength of SupportD- CoverageC- Formula Quality
Zinc · 30 mgCopper · 2 mg

Chelated zinc and copper provide a useful mineral pair but only narrow vision support. The softgel may aid delivery of the broader formula.

No lutein, zeaxanthin, antioxidant vitamin framework, or omega-3 is present. It is a testosterone formula rather than an eye product.

Study evidence
Copper Supportive 7 studies
Zinc Supportive 39 studies

Ingredients

IngredientAmount per serving
Calories
35 Calorie(s)
Total Fat
2 Gram(s)
Protein
1 Gram(s)
Zinc (Zinc Methionine)
 30 mg
Copper (Copper Citrate)
 2 mg
Medium Chain Triglyceride Oil
900 mg
Pumpkin Seed Oil
900 mg
Nettle root extract
300 mg
Plant Sterols
150 mg
Asian Ginseng root extract
100 mg
LJ100 (Tongkat Ali Root Extract)
 100 mg
Chrysin
99 mg
Gamma Oryzanol
50 mg
BioPerine Complex
6 mg
Men 18–50
Report overview
Zinc (Zinc Methionine) · 30 mg OverallScore83
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The methionine-chelated zinc offers strong absorption potential in a readily released softgel. The dose sits in a robust daily range without exceeding the usual upper limit, while copper is included in a suitable balancing amount. The premium form adds quality, but cost per serving remains high.

View ingredientView products
Stinging Nettle · 300 mg OverallScore78
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

Root extract is well aligned with the testosterone-focused formula. The disclosed amount falls in an effective extract range, but no concentration ratio or active marker is provided. The high serving cost is partly supported by the effective dose and broader formula.

View ingredientView products
Copper (Copper Citrate) · 2 mg OverallScore76
B Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

copper citrate is a well-absorbed organic copper form, and the 2 mg dose exactly matches the collection median. The zinc-to-copper ratio is within the preferred range. The serving cost is high, which weakens practical value despite the broader formula.

View ingredientView products
Loading alternative details
71 Performance

Prostate Health

Whitaker Nutrition
A more purposeful active profile is better aligned with the original’s main use because saw palmetto, nettle, beta-sitosterol, cranberry, lycopene, selenium, zinc, and copper form a coherent prostate formula. Zinc oxide, high zinc and selenium, missing extract standardization, and a high recurring cost reduce its appeal.
81 Performance

Ortho Thyroid

Protocol For Life Balance
A more purposeful active profile is better aligned with the original’s main use because meaningful tyrosine, well-specified minerals, and standardized guggul and ashwagandha create a coherent thyroid-support formula. Iodine, tyrosine, guggul, and ashwagandha can complicate thyroid conditions or thyroid-medicine management, so affected users should seek individualized guidance.
82 Performance

Thyroid Energy

NOW
A more purposeful active profile is better aligned with the original’s main use because meaningful tyrosine, well-specified minerals, and standardized guggul and ashwagandha create a coherent thyroid-support formula. Iodine, tyrosine, guggul, and ashwagandha can complicate thyroid conditions or thyroid-medicine management, so affected users should seek individualized guidance.
83 Budget

Zinc 30 mg

Nature's Life
Lower serving cost makes it the more economical option, while zinc picolinate with copper provides a coherent, economical mineral-balance formula. The zinc amount is substantial, and repeated copper entries make the total less clear than it should be.
80 Budget

PreserVision AREDS 2 Formula

Bausch & Lomb
Lower serving cost makes it the more economical option, while the focused AREDS-style formula closely matches its intended vision-support use with substantial lutein, zeaxanthin, antioxidant vitamins, zinc, and copper. High zinc and vitamin E amounts make it inappropriate as a casual general multivitamin and favor clinician-guided use for the intended population.
81 Budget

Zinc Plus 25 mg

Nature's Answer
Lower serving cost makes it the more economical option, while favorable zinc forms and active vitamin B6 support a well-focused formula at a low serving cost. Repeated zinc entries obscure the form split, while the copper amount provides only modest balance against substantial zinc.
78 Value

Zinc Copper Amino Acid Chelate with Kelp & Pumpkin Seed

Solaray
Ingredient quality and serving value are better balanced here because amino acid chelates and included copper support absorption and mineral balance at excellent serving value. The 50 mg zinc amount exceeds the adult upper intake level and remains poorly balanced against only 2 mg copper.
77 Value

Healthy Eyes Lutein and Antioxidants

21st Century
Ingredient quality and serving value are better balanced here because lutein and antioxidant vitamins fit basic eye support, but the lutein amount is modest and several mineral forms are weak. Zinc reaches the adult daily upper limit, so prolonged use may cause nausea or copper imbalance despite the included copper.
81 Value

Thyroid Energy

NOW
Ingredient quality and serving value are better balanced here because meaningful tyrosine, well-specified minerals, and standardized guggul and ashwagandha create a coherent thyroid-support formula. Iodine, tyrosine, guggul, and ashwagandha can complicate thyroid conditions or thyroid-medicine management, so affected users should seek individualized guidance.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  2. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  3. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  4. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  5. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial.
    Namazi N; Esfanjani AT; Heshmati J; Bahrami A · Pakistan journal of biological sciences : PJBS · 2012
    Randomized trial50 participantsAnti-Inflammatory Support forStinging Nettle
  6. Urtica Dioica Root Extract on Clinical and Biochemical Parameters in Patients with Benign Prostatic Hyperplasia, Randomized Controlled Trial.
    Akbar Karami A; Sheikhsoleimani M; Reza Memarzadeh M; Haddadi E; Bakhshpour M; Mohammadi N; Mehdi Mirhashemi S · Pakistan journal of biological sciences : PJBS · 2021
    Randomized trial60 participantsAnti-Inflammatory Support forStinging Nettle
  7. Safety, Tolerability, and Efficacy of Hox Alpha, a Dry Extract from Stinging Nettle Leaves versus OTC NSAIDs in Osteoarthritis: A Retrospective, Propensity-Matched 12-Week Analysis from the German Pain e-Registry (SIPHARO Study).
    Überall MA; Küster MA; Müller-Schwefe PCG; Müller-Schwefe GHH · Journal of pain research · 2026
    Cohort study2,146 participantsAnti-Inflammatory Support forStinging Nettle
  8. [Recommendations of the DGRh Committee on Complementary Medicine and Nutrition on the application of selected phytotherapeutic drugs and herbal medicines in rheumatology].
    Keyßer G; Seifert O; Frohne I; Michalsen A; Pfeil A; Reuß-Borst M; Sander O · Zeitschrift fur Rheumatologie · 2025
    Guideline / consensusAnti-Inflammatory Support forStinging Nettle
  9. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain
    C Randall, H Randall, F Dobbs, C Hutton, H Sanders · Journal of the Royal Society of Medicine · 2000
    Randomized trial27 participantsAnti-Inflammatory Support forStinging Nettle
  10. Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent.
    Bao B; Prasad AS; Beck FW; Fitzgerald JT; Snell D; Bao GW; Singh T; Cardozo LJ · The American journal of clinical nutrition · 2010
    Randomized trial40 participantsAnti-Inflammatory Support forZinc
  11. Zinc Supplementation in Individuals with Prediabetes and type 2 Diabetes: a GRADE-Assessed Systematic Review and Dose-Response Meta-analysis.
    Nazari M; Nikbaf-Shandiz M; Pashayee-Khamene F; Bagheri R; Goudarzi K; Hosseinnia NV; Dolatshahi S; Omran HS; Amirani N; Ashtary-Larky D; Asbaghi O; Ghanavati M · Biological trace element research · 2024
    Meta-analysis23 studies pooledAnti-Inflammatory Support forZinc
  12. The Effects of Zinc Supplementation on C-Reactive Protein and Inflammatory Cytokines: A Meta-Analysis and Systematical Review.
    Ceylan MN; Akdas S; Yazihan N · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
    Meta-analysis73 studies pooledAnti-Inflammatory Support forZinc
  13. The Effects of Zinc Sulfate Supplementation on Serum Copeptin, C-Reactive Protein and Metabolic Markers in Zinc-Deficient Diabetic Patients on Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Hosseini R; Montazerifar F; Shahraki E; Karajibani M; Mokhtari AM; Dashipour AR; Ferns GA; Jalali M · Biological trace element research · 2021
    Randomized trial46 participantsAnti-Inflammatory Support forZinc
  14. Zinc supplementation and cardiovascular disease risk factors: A GRADE-assessed systematic review and dose-response meta-analysis.
    Nazari M; Ashtary-Larky D; Nikbaf-Shandiz M; Goudarzi K; Bagheri R; Dolatshahi S; Omran HS; Amirani N; Ghanavati M; Asbaghi O · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2023
    Meta-analysis75 studies pooledAnti-Inflammatory Support forZinc
  15. Association between composite dietary antioxidant index and handgrip strength in American adults: Data from National Health and Nutrition Examination Survey (NHANES, 2011-2014).
    Wu D; Wang H; Wang W; Qing C; Zhang W; Gao X; Shi Y; Li Y; Zheng Z · Frontiers in nutrition · 2024
    Cross-sectional study6,019 participantsFitness forZinc
  16. Serum essential elements and muscle health in Chinese adults: a community-based study.
    Ye H; Wang D; Liu S; Yao N; Gui Z; Huang Z; Zeng Y; Liu L; Wan H; Shen J · Nutrition & metabolism · 2025
    Cross-sectional study5,389 participantsFitness forZinc
  17. [Survey of the dietary status and physical activity level and fitness of college freshmen in Chengdu].
    Han H; Lv X; Wang D · Wei sheng yan jiu = Journal of hygiene research · 2010
    Cross-sectional study1,200 participantsFitness forZinc
  18. A comprehensive review of the physiology and evidence base to guide the use of ergogenic and medical supplements for enhanced cycling performance.
    Rowland A; Edwards S; Prieto-Bellver G; Menz B; Rowland A; Cornelisse E; Karapetis CS; Wallen MP; Hopkins AM · Journal of the International Society of Sports Nutrition · 2026
    Narrative reviewFitness forZinc
  19. Minerals and Sarcopenia in Older Adults: An Updated Systematic Review.
    van Dronkelaar C; Fultinga M; Hummel M; Kruizenga H; Weijs PJM; Tieland M · Journal of the American Medical Directors Association · 2023
    Systematic review45 studies pooledFitness forZinc
  20. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  21. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  22. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  23. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  24. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  25. Menkes disease and response to copper histidine: An Indian case series.
    Yoganathan S; Sudhakar SV; Arunachal G; Thomas M; Subramanian A; George R; Danda S · Annals of Indian Academy of Neurology · 2022
    Case series4 participantsHair Health forCopper
  26. Trace element levels in alopecia areata.
    Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
    Case-control study100 participantsHair Health forCopper
  27. UV damage to hair and the effect of antioxidants and metal chelators.
    Millington KR; Marsh JM · International journal of cosmetic science · 2021
    In vitro / ex vivo studyHair Health forCopper
  28. Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
    Marsh JM; Davis MG; Lucas RL; Reilman R; Styczynski PB; Li C; Mamak M; McComb DW; Williams RE; Godfrey S; Navqi KR; Chechik V · International journal of cosmetic science · 2016
    In vitro / ex vivo studyHair Health forCopper
  29. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  30. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  31. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  32. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  33. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  34. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  35. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  36. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  37. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  38. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  39. Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial.
    Melamed E; Dabbah J; Israel T; Kan I; Pinzur MS; Roth T; Borkow G · Advances in wound care · 2026
    Randomized trialSkin Health forCopper
  40. Improvement of facial skin characteristics using copper oxide containing pillowcases: a double-blind, placebo-controlled, parallel, randomized study.
    Borkow G; Gabbay J; Lyakhovitsky A; Huszar M · International journal of cosmetic science · 2010
    Randomized trial57 participantsSkin Health forCopper
  41. Radially Electrospun Fibrous Membrane Incorporated with Copper Peroxide Nanodots Capable of Self-Catalyzed Chemodynamic Therapy for Angiogenesis and Healing Acceleration of Diabetic Wounds.
    Huang Y; Qi L; Liu Z; Jiang Y; Wang J; Liu L; Li Y; Zhang L; Feng G · ACS applied materials & interfaces · 2023
    Animal experimentSkin Health forCopper
  42. Engineering copper nanoparticle/polysaccharide-immobilized cotton gauze for accelerated healing of Staphylococcus aureus-infected dermal wounds.
    Sahoo M; Banerjee T; Virkar S; Das S; Biswas S; Mitra D · Journal of materials chemistry. B · 2026
    Animal experimentSkin Health forCopper
  43. Stimulation of Healing of Non-Infected Stagnated Diabetic Wounds by Copper Oxide-Impregnated Wound Dressings.
    Melamed E; Rovitsky A; Roth T; Assa L; Borkow G · Medicina (Kaunas, Lithuania) · 2021
    Single-arm trialSkin Health forCopper
  44. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  45. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  46. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  47. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  48. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forZinc
  49. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  50. What did we learn in 35 years of research on nutrition and supplements for age-related macular degeneration: a systematic review.
    Pameijer EM; Heus P; Damen JAA; Spijker R; Hooft L; Ringens PJ; Imhof SM; van Leeuwen R · Acta ophthalmologica · 2023
    Systematic review27 studies pooledVision Support forCopper
  51. Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2.
    Agrón E; Mares J; Clemons TE; Swaroop A; Chew EY; Keenan TDL; AREDS and AREDS2 Research Groups · Ophthalmology · 2021
    Cohort study8,242 participantsVision Support forCopper
  52. Association between late age-related macular degeneration and dietary intake of copper, iron, zinc and selenium: a 2005-2008 NHANES cross-sectional observational study.
    Lu Y; Li C; Liu Y; Wu T; Lu P · BMC ophthalmology · 2025
    Observational study4,996 participantsVision Support forCopper
  53. Associations between dietary nutrient intake and the risk of multiple age-related ocular diseases: evidence from longitudinal analysis.
    Yang Y; Zou H · The journal of nutrition, health & aging · 2026
    Cohort study103,192 participantsVision Support forCopper
  54. Dietary habits and dietary nutrient intake in patients with age-related macular degeneration: A case-control study.
    Šalková Kráľová J; Kolář P; Kapounová Z; Veselý P; Derflerová Brázdová Z · Central European journal of public health · 2023
    Case-control study151 participantsVision Support forCopper
  55. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  56. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  57. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  58. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  59. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc