Product Image

Power to Sleep PM 6 mg Melatonin

Irwin Naturals
4.4
★ ★ ★ ★ ★
(1030 ratings)
GABA 100 mg
Theanine 50 mg
Ashwagandha 150 mg
Melatonin 6 mg
Protein 1 Gram(s)
Product Image
Score77
A coherent bedtime stack with direct circadian and relaxation support. High-dose melatonin and modest, unstandardized supporting ingredients are the main trade-offs.
How scoring works
Quantity:60 Liquid(s) • (30 servings)
Goals:
Sleep Support
Stress Relief
Mood Support

Score 77

A coherent bedtime stack with direct circadian and relaxation support. High-dose melatonin and modest, unstandardized supporting ingredients are the main trade-offs.
How scoring works

Also available as

1 option
2 mg melatonin • 60 Liquid(s) servings 2 mg melatonin • 60 Liquid(s) • 30 servings $19.50 ($0.65 per serving)
$20.20($0.67 per serving)
Vitacost
$ 20.99
iHerb
$ 20.99
Pure Formulas
$ 20.99
Amazon
$ 20.20
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Analysis

Melatonin directly supports sleep timing, while hops, lemon balm, passionflower, GABA, L-theanine, and ashwagandha cover several relaxation pathways. The active amounts are listed individually and the blend is clearly designed for bedtime use.

Six milligrams of melatonin exceeds a conservative starting range and may cause next-day grogginess or vivid dreams. Ashwagandha lacks withanolide standardization, theanine is only a supporting amount, and the magnesium contribution is too small to matter much.

The formula best fits adults who have tolerated melatonin and want several calming ingredients in one liquid softgel routine. People seeking daytime stress support, a low-dose sleep aid, or a non-sedating mood formula should choose a more targeted option.

Who is it for
  • Adults who already tolerate melatonin
  • People seeking multi-ingredient bedtime support
  • Users wanting calming botanicals with GABA and theanine
Best for
  • Sleep-onset support
  • Evening relaxation
  • Short-term bedtime routines

Pros

  • Covers circadian and relaxation pathways
  • Clearly lists active amounts
  • Includes several complementary calming botanicals

Cons

  • Melatonin amount is high for a starting dose
  • Ashwagandha lacks standardization
  • Magnesium and theanine are modest

Warnings

  • Six milligrams of melatonin may cause next-day drowsiness, vivid dreams, or impaired driving
  • Combining the formula with sleep medicines, sedating antihistamines, alcohol, or other calming supplements may cause excessive sedation
  • Ashwagandha may be unsuitable with thyroid medicine or immune-suppressing treatment

Nutrient quality

73 High impact

Melatonin, calming herbs, GABA, ashwagandha, and theanine form a broad sleep blend. Several core amounts are meaningful.

Ingredient transparency

81 Highest impact

Active amounts are individually disclosed without a proprietary blend. Several extract standards, complete directions, and non-active ingredients remain unavailable.

Customer satisfaction

84 Highest impact

The aggregate rating is generally favorable and has substantial review volume. No specific comments are supplied, so repeated complaints and purpose alignment cannot be confirmed directly.

Value for money

69 High impact

Value is reasonable for the dose quality and formula focus. Most ingredients support the core purpose.

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Goals

Sleep Support
Sleep Support
Impact
Highest effect
A Goal FitA Strength of SupportB+ CoverageB+ Formula Quality
Magnesium · 12 mgMelatonin · 6 mgTheanine · 50 mg

Melatonin provides direct circadian support, while ashwagandha, hops, lemon balm, passionflower, GABA, and theanine target relaxation. Magnesium is only a token amount and the relatively high melatonin dose may cause next-day grogginess in sensitive users.

The formula covers circadian regulation, inhibitory signaling, botanical relaxation, and stress resilience. The ingredients form a clear bedtime stack, though the melatonin amount may be more than some users need.

Study evidence
Ashwagandha Supportive 18 studies
GABA Supportive 4 studies
Magnesium Supportive 23 studies
Melatonin Supportive 181 studies
Theanine Supportive 8 studies
Stress Relief
Stress Relief
Impact
High effect
B+ Goal FitB- Strength of SupportB+ CoverageB+ Formula Quality
Ashwagandha · 150 mgMagnesium · 12 mgGABA · 100 mgTheanine · 50 mg

Melatonin and several calming botanicals may support sleep-related recovery and evening relaxation. Valerian, lemon balm, passionflower, ashwagandha, or theanine provide complementary calming mechanisms.

Several botanical extracts are modest or lack marker standardization, and the formula is aimed more at sleep than daytime stress resilience. Melatonin can cause next-day drowsiness and may not suit people who need a non-sedating option.

Study evidence
Ashwagandha Supportive 47 studies
Melatonin Supportive 21 studies
Theanine Supportive 16 studies
Mood Support
Mood Support
Impact
Moderate effect
D+ Goal FitD+ Strength of SupportC- CoverageC+ Formula Quality
Magnesium · 12 mgAshwagandha · 150 mg

L-theanine, GABA, ashwagandha, and calming herbs provide limited support for stress-related relaxation. Six milligrams of melatonin makes sleep the clear focus rather than stable daytime mood.

Most supporting active amounts are modest, and the botanical extracts do not disclose potency markers. The higher melatonin amount may increase next-day drowsiness or add to sedation from sleep medicines.

Study evidence
Ashwagandha Supportive 29 studies
GABA Supportive 12 studies
Magnesium Supportive 60 studies
Theanine Supportive 12 studies

Ingredients

IngredientAmount per serving
Calories
15 Calorie(s)
Total Fat
1 Gram(s)
Total Carbohydrates
1 Gram(s)
Protein
1 Gram(s)
Calcium (Calcium Citrate)
 11 mg
Magnesium (Magnesium Citrate)
 12 mg
Flaxseed Oil
1000 mg
Ashwagandha Root Extract
150 mg
Hops flower extract
150 mg
Lemon Balm extract
150 mg
Passionflower Flower Extract
150 mg
Gamma-Aminobutyric Acid
100 mg
L-Theanine
50 mg
Melatonin
6 mg
BioPerine Complex
6 mg
Adults 18–50 Women
Report overview
GABA · 100 mg OverallScore73
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD- Value

The 100 mg GABA amount is clearly stated but modest for a standard, unbranded source. Liquid-filled softgels are practical, yet the formula relies more heavily on melatonin and calming botanicals for its sleep purpose. The serving cost is high for the GABA delivered, and 6 mg melatonin raises the likelihood of next-day drowsiness, vivid dreams, or excessive sedation with sleep medicines.

View ingredientView products
Theanine · 50 mg OverallScore70
B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

The explicitly identified L-theanine is individually disclosed at a mild supporting dose. Its generic form has no branded source or purity claim, which limits evidence for premium ingredient quality. Theanine is expensive for the active amount, and the accompanying ingredients do not qualify for a value adjustment.

View ingredientView products
Ashwagandha · 150 mg OverallScore54
D+ Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyD- Value

The generic root extract lacks a stated withanolide standard. BioPerine may improve absorption, while the clearly listed amount remains below common clinical extract targets. The serving cost is above the collection median for this uncertain potency.

View ingredientView products
Loading alternative details
71 Performance

Power to Sleep PM

Irwin Naturals
<p>Compared with the original, it retains Ashwagandha, GABA, and Melatonin and remains aligned with sleep support, and stress relief. Valerian, ashwagandha, hops, lemon balm, passionflower, and melatonin create broad nighttime support. GABA and theanine are modest, while flaxseed oil adds little sleep value and the sedative stack may cause morning grogginess.</p>
78 Performance

Serenelle

Quality Of Life
<p>Compared with the original, it retains Ashwagandha, GABA, and Theanine and remains aligned with sleep support, and stress relief. Sensoril ashwagandha, theanine, PharmaGABA, and lemon balm are supplied at meaningful amounts in a focused calming formula. Strong ingredient quality supports the cost, though the serving is not especially economical.</p>
75 Performance

Ultra Strength Goodbye Stress

OLLY
<p>Compared with the original, it retains Ashwagandha, GABA, and Theanine and remains aligned with sleep support, and stress relief. Ashwagandha, GABA, theanine, and lemon balm create a coherent calming blend, but all four doses are modest. Large aggregate rating volume helps reliability, while mixed satisfaction and limited potency weaken value.</p>
79 Budget

Superior Sleep

Doctor's Best
<p>It lowers recurring cost while retaining Ashwagandha, GABA, and Melatonin from the original's ingredient focus. Ashwagandha, theanine, GABA, melatonin, and 5-HTP are all supplied at meaningful amounts for sleep support. The 5 mg melatonin dose may cause morning grogginess, and 5-HTP can raise serotonin-related risk with SSRIs, SNRIs, MAO inhibitors, or tramadol.</p>
72 Budget

Power to Sleep PM

Irwin Naturals
<p>It lowers recurring cost while retaining Ashwagandha, GABA, and Melatonin from the original's ingredient focus. Valerian, ashwagandha, hops, lemon balm, passionflower, and melatonin create broad nighttime support. The larger format improves value, though modest GABA and theanine plus low-value flaxseed oil remain limitations.</p>
83 Budget

GABA Soothe

Jarrow Formulas
<p>It lowers recurring cost while retaining Ashwagandha, GABA, and Theanine from the original's ingredient focus. Sensoril ashwagandha, theanine, and GABA create a concise calming formula at useful amounts. Focused ingredients and reasonable serving economics support strong practical value.</p>
86 Value

Anxiety & Stress Relief

Nature's Bounty
<p>It combines a lower recurring cost with Ashwagandha, and Theanine, supporting a practical value case against the original. Ashwagandha and theanine provide a focused, meaningfully dosed stress-support pair without unrelated actives. Ashwagandha may affect thyroid activity in people using thyroid hormone.</p>
85 Value

3 a.m. Melatonin Fast Dissolve Lavender Vanilla

Natrol
<p>It combines a lower recurring cost with Melatonin, and Theanine, supporting a practical value case against the original. Fast-dissolve melatonin and a modest L-theanine amount create a simple, economical option for sleep onset. The formula offers little depth beyond those two actives, and melatonin can cause next-day drowsiness in sensitive users.</p>
83 Value

ZenMind

NutriCology
<p>It retains GABA, and Theanine, but the supplied cost data does not establish a cheaper serving than the original. Branded L-theanine and a substantial GABA amount form a focused relaxation stack with fully disclosed doses. The combined calming amount may cause drowsiness, especially with alcohol, sleep aids, or other sedating medicines.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults.
    Deshpande A; Irani N; Balkrishnan R; Benny IR · Sleep medicine · 2021
    Randomized trial150 participantsSleep Support forAshwagandha
  2. Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
    Byun JI; Shin YY; Chung SE; Shin WC · Journal of clinical neurology (Seoul, Korea) · 2020
    Randomized trial40 participantsSleep Support forGABA
  3. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  4. Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
    Tsukinaga A; Mihara T; Takeshima T; Tomita M; Goto T · Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Meta-analysis516 participants8 studies pooledSleep Support forMelatonin
  5. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.
    Sletten TL; Magee M; Murray JM; Gordon CJ; Lovato N; Kennaway DJ; Gwini SM; Bartlett DJ; Lockley SW; Lack LC; Grunstein RR; Rajaratnam SMW; Delayed Sleep on Melatonin (DelSoM) Study Group · PLoS medicine · 2019
    Randomized trial116 participantsSleep Support forMelatonin
  6. The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis.
    Bulman A; D'Cunha NM; Marx W; Turner M; McKune A; Naumovski N · Sleep medicine reviews · 2025
    Meta-analysis897 participants19 studies pooledSleep Support forTheanine
  7. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
    Sarris J; Byrne GJ; Cribb L; Oliver G; Murphy J; Macdonald P; Nazareth S; Karamacoska D; Galea S; Short A; Ee C; Birling Y; Menon R; Ng CH · Journal of psychiatric research · 2020
    Randomized trial46 participantsSleep Support forTheanine
  8. A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.
    West RE; Biswas A; Rao R; Tayade H; Ademola J · Journal of medicine and life · 2026
    Randomized trial141 participantsMood Support forAshwagandha
  9. Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
    Fatima K; Malik J; Muskan F; Raza G; Waseem A; Shahid H; Jaffery SF; Khan U; Zaheer MK; Shaikh Y; Rashid AM · Human psychopharmacology · 2024
    Meta-analysis254 participants5 studies pooledMood Support forAshwagandha
  10. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
    Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
    Randomized trial64 participantsMood Support Stress Relief forAshwagandha
  11. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
    McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
    Randomized trial186 participantsMood Support forAshwagandha
  12. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
    Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
    Meta-analysis29 participants29 studies pooledMood Support forAshwagandha
  13. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
    Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
    Randomized trial63 participantsMood Support forGABA
  14. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
    Deligiannidis KM; Kroll-Desrosiers AR; Mo S; Nguyen HP; Svenson A; Jaitly N; Hall JE; Barton BA; Rothschild AJ; Shaffer SA · Psychoneuroendocrinology · 2017
    Cohort study56 participantsMood Support forGABA
  15. The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
    Wang J; Liu G; Xu K; Ai K; Huang W; Zhang J · Human brain mapping · 2023
    Case-control study69 participantsMood Support forGABA
  16. Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis.
    Truong V; Cheng PZ; Lee HC; Lane TJ; Hsu TY; Duncan NW · Psychiatry research. Neuroimaging · 2021
    Observational studyMood Support forGABA
  17. Systematic review of gamma-aminobutyric-acid inhibitory deficits across the reproductive life cycle.
    Vigod SN; Strasburg K; Daskalakis ZJ; Blumberger DM · Archives of women's mental health · 2014
    Systematic review11 studies pooledMood Support forGABA
  18. Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.
    Wang H; Jin M; Xie M; Yang Y; Xue F; Li W; Zhang M; Li Z; Li X; Jia N; Liu Y; Cui X; Hu G; Dong L; Wang G; Yu Q · Journal of affective disorders · 2023
    Meta-analysis4,049 participants52 studies pooledMood Support forMagnesium
  19. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsMood Support forMagnesium
  20. Magnesium supplementation as an adjunct to fluoxetine therapy for depression.
    Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
    Randomized trial40 participantsMood Support forMagnesium
  21. The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
    Afsharfar M; Shahraki M; Shakiba M; Asbaghi O; Dashipour A · Clinical nutrition ESPEN · 2021
    Randomized trial46 participantsMood Support forMagnesium
  22. Dietary magnesium intake and risk of depression.
    Sun C; Wang R; Li Z; Zhang D · Journal of affective disorders · 2019
    Cross-sectional study17,730 participantsMood Support forMagnesium
  23. l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
    Shamabadi A; Kafi F; Arab Bafrani M; Asadigandomani H; A Basti F; Akhondzadeh S · Journal of affective disorders · 2023
    Randomized trial60 participantsMood Support forTheanine
  24. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
    Ritsner MS; Miodownik C; Ratner Y; Shleifer T; Mar M; Pintov L; Lerner V · The Journal of clinical psychiatry · 2011
    Randomized trial60 participantsMood Support Stress Relief forTheanine
  25. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.
    Williams JL; Everett JM; D'Cunha NM; Sergi D; Georgousopoulou EN; Keegan RJ; McKune AJ; Mellor DD; Anstice N; Naumovski N · Plant foods for human nutrition (Dordrecht, Netherlands) · 2020
    Systematic review9 studies pooledMood Support forTheanine
  26. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsMood Support Stress Relief forTheanine
  27. Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.
    Unno K; Tanida N; Ishii N; Yamamoto H; Iguchi K; Hoshino M; Takeda A; Ozawa H; Ohkubo T; Juneja LR; Yamada H · Pharmacology, biochemistry, and behavior · 2014
    Randomized trial20 participantsMood Support forTheanine
  28. Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial.
    Thanawala S; Shah R; Alluri KV; Bhupathiraju K; Desomayanandanam P; Bhuvenendran A · Medicine · 2026
    Randomized trial135 participantsSleep Support forAshwagandha
  29. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
    Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
    Randomized trial130 participantsSleep Support Stress Relief forAshwagandha
  30. Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
    Langade D; Thakare V; Kanchi S; Kelgane S · Journal of ethnopharmacology · 2021
    Randomized trial80 participantsSleep Support forAshwagandha
  31. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study.
    Langade D; Kanchi S; Salve J; Debnath K; Ambegaokar D · Cureus · 2020
    Randomized trial60 participantsSleep Support forAshwagandha
  32. Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.
    Imafuku F; Yamamoto K; Tanaka E; Aoki R; Nishino S · Nutrients · 2023
    Randomized trial160 participantsSleep Support forGABA
  33. Reduced γ-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: a link to major depressive disorder?
    Plante DT; Jensen JE; Schoerning L; Winkelman JW · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
    Case-control study40 participantsSleep Support forGABA
  34. GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
    Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
    Randomized trial30 participantsSleep Support forGABA
  35. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
    Khalid S; Bashir S; Mehboob R; Anwar T; Ali M; Hashim M; Waseem H; Basharat S · Frontiers in endocrinology · 2024
    Randomized trial320 participantsSleep Support forMagnesium
  36. Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.
    Zhang Y; Chen C; Lu L; Knutson KL; Carnethon MR; Fly AD; Luo J; Haas DM; Shikany JM; Kahe K · Sleep · 2022
    Cohort study3,964 participantsSleep Support forMagnesium
  37. Lidocaine vs. magnesium: effect on analgesia after a laparoscopic cholecystectomy.
    Saadawy IM; Kaki AM; Abd El Latif AA; Abd-Elmaksoud AM; Tolba OM · Acta anaesthesiologica Scandinavica · 2010
    Randomized trial120 participantsSleep Support forMagnesium
  38. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
    Abbasi B; Kimiagar M; Sadeghniiat K; Shirazi MM; Hedayati M; Rashidkhani B · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013
    Randomized trial46 participantsSleep Support forMagnesium
  39. A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
    Barna O; Lohoida P; Holovchenko Y; Bazylevych A; Velychko V; Hovbakh I; Bula L; Shechter M · Nutrition journal · 2021
    Randomized trial175 participantsSleep Support forMagnesium
  40. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  41. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  42. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  43. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin
  44. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsSleep Support forTheanine
  45. Comparison Between Efficacy of Oral Melatonin and Oral L-theanine in Improving Sleep in Cancer Patients Suffering From Insomnia: A Randomised Double-blinded Placebo-controlled Study.
    Kurdi MS; As A; Ladhad DA; Mitragotri MV; Baiju A · Indian journal of palliative care · 2024
    Randomized trial120 participantsSleep Support forTheanine
  46. In Search of a Safe Natural Sleep Aid.
    Rao TP; Ozeki M; Juneja LR · Journal of the American College of Nutrition · 2016
    Narrative reviewSleep Support forTheanine
  47. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
    Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
    Randomized trial60 participantsStress Relief forAshwagandha
  48. Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
    Mishra DN; Kumar M · Heliyon · 2024
    Randomized trial60 participantsStress Relief forAshwagandha
  49. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
    Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
    Randomized trial60 participantsStress Relief forAshwagandha
  50. The impact of oral melatonin on pain and anxiety reduction during venipuncture in pediatric patients: a double-blind randomized clinical trial.
    Rahafard S; Akbari Jokar Z; Hosseini SA; Alaee E · Annals of medicine and surgery (2012) · 2024
    Randomized trial202 participantsStress Relief forMelatonin
  51. Comparison of Effects of Melatonin and Gabapentin on Post Operative Anxiety and Pain in Lumbar Spine Surgery: A Randomized Clinical Trial.
    Javaherforooshzadeh F; Amirpour I; Janatmakan F; Soltanzadeh M · Anesthesiology and pain medicine · 2022
    Randomized trial90 participantsStress Relief forMelatonin
  52. Melatonin for pre- and postoperative anxiety in adults.
    Hansen MV; Halladin NL; Rosenberg J; Gögenur I; Møller AM · The Cochrane database of systematic reviews · 2015
    Meta-analysis774 participants12 studies pooledStress Relief forMelatonin
  53. Effects of melatonin intake on depression and anxiety in postmenopausal women: a systematic review and meta-analysis of randomised controlled trials.
    Demirhan Kayacik A; İlcioglu K · Archives of women's mental health · 2024
    Meta-analysis441 participants5 studies pooledStress Relief forMelatonin
  54. Premedication effect of melatonin on propofol induction dose for anesthesia, anxiety, orientation and sedation after abdominal surgery: a double-blinded randomized trial.
    Norouzi A; Fateh S; Modir H; Kamali A; Akrami L · Medical gas research · 2020
    Randomized trial88 participantsStress Relief forMelatonin
  55. Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.
    White DJ; de Klerk S; Woods W; Gondalia S; Noonan C; Scholey AB · Nutrients · 2016
    Randomized trial34 participantsStress Relief forTheanine
  56. Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED · Neurology and therapy · 2024
    Randomized trial30 participantsStress Relief forTheanine
  57. A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
    Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
    Randomized trialStress Relief forTheanine