Activated B-Complex High Bioavailability
Swanson
Activated B-Complex High Bioavailability
4.9
★ ★ ★ ★ ★
(1190 ratings)
Vitamin B6 25 mg
Thiamin 36 mg
PABA 25 mg
Choline 25 mg
Vitamin B12 250 mcg
Vitamin B5 25 mg
Riboflavin 25 mg
Score 95.0
A top-tier B-complex featuring highly bioavailable, activated forms of essential B vitamins for superior absorption and efficacy, offered at an exceptionally affordable price point.
Quantity: 60 Veggie Cap(s)Servings size: 1 Veggie Capsule(s) (60 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
Cognitive Support
leaderboard Score 95.0
A top-tier B-complex featuring highly bioavailable, activated forms of essential B vitamins for superior absorption and efficacy, offered at an exceptionally affordable price point.
insights Analysis
Swanson's Activated B-Complex High Bioavailability is an impressive formulation, distinguishing itself by offering B vitamins in their metabolically active and readily usable forms. This includes Benfotiamine for B1, Riboflavin 5-Phosphate for B2, Pyridoxal 5-Phosphate for B6, Calcium L-5-Methyltetrahydrofolate for Folate, and Methylcobalamin for B12, alongside Pantethine (B5) and a no-flush form of Niacinamide (B3). This emphasis on activated forms is crucial for maximizing nutrient absorption and efficacy, especially for individuals with genetic predispositions like MTHFR mutations or digestive challenges. The product's extremely competitive price of $0.20 per serving makes it an exceptional value proposition, delivering premium bioavailability without the premium cost, which is frequently lauded in online reviews for its noticeable positive effects.
- Contains activated forms of most B vitamins (B1 as Benfotiamine, B2 as Riboflavin 5-Phosphate, B5 as Pantethine, B6 as P-5-P, B9 as Methylfolate, B12 as Methylcobalamin) for superior bioavailability and direct utilization.
- Includes 'no-flush' Niacinamide (as Inositol Hexanicotinate), making it gentler on the stomach and skin.
- Offers exceptional value with a very low price per serving for such a high-quality, activated formula.
- Highly praised in online reviews for its effectiveness in boosting energy and supporting cognitive function.
- The Biotin dosage (25mcg) is relatively modest compared to some B-complexes specifically marketed for hair, skin, and nail benefits.
- The Choline dosage (25mg) is lower than in dedicated choline supplements, providing more of a supplementary role than a primary source.
- While activated forms are generally well-tolerated, individuals starting any new supplement should observe for any personal sensitivities.
$13.99($0.23 per serving)
 iHerb | $ 13.99 | |
 Amazon | $ 49.25 |
bolt Effectiveness for goals
B vitamins are essential for energy production, cellular metabolism, and nervous system function. They collectively support the conversion of food into energy, promote healthy red blood cell formation, and maintain proper brain function. These vitamins are crucial for overall vitality and well-being.
Activated forms are already in their coenzyme state, meaning the body does not need to convert them before utilization. This can enhance their bioavailability and efficiency, particularly for individuals with genetic variations affecting conversion pathways. It ensures the vitamins are readily available for immediate metabolic processes.
High bioavailability means a greater proportion of the ingested nutrient is absorbed and utilized by the body. For B vitamins, this ensures that adequate amounts reach the cells where they are needed for energy production and various metabolic functions. It can lead to more efficient nutrient delivery and support compared to less bioavailable forms.
Methylcobalamin is an active, coenzyme form of Vitamin B12, directly usable by the body without conversion. It plays a crucial role in methylation processes, nerve tissue health, and red blood cell formation. This form is often favored due to its immediate metabolic availability and effectiveness.
Calcium L-5-Methyltetrahydrofolate (5-MTHF) is the biologically active form of folate, meaning it's readily used by cells without requiring enzymatic conversion. Unlike synthetic folic acid, it directly supports DNA synthesis, cell division, and homocysteine metabolism. This form is often preferred for its direct metabolic utility, especially for individuals with certain genetic variations.
schedule Dosage, timing & forms
B-complex supplements are generally recommended to be taken with food to enhance absorption and minimize potential stomach upset. Many prefer taking them in the morning as B vitamins are involved in energy metabolism. Always follow the specific serving instructions on the product label for the best results.
Activated forms of B vitamins are body-ready, meaning they do not require conversion by the liver before being utilized. This can be particularly beneficial for individuals with genetic variations that affect nutrient metabolism. These forms are often chosen for potentially superior bioavailability and direct cellular use.
Inositol Hexanicotinate is a 'no-flush' form of niacin, where niacin is bound to inositol, allowing a slower release. This form typically reduces the likelihood of the common 'niacin flush' sensation, which is a temporary redness and warmth. Consequently, it may be dosed differently and is often preferred for individuals sensitive to standard niacin.
Taking a B-complex daily is common for those seeking to support overall wellness and energy metabolism. For optimal absorption and to avoid potential sleep disturbances due to energy support, it is often recommended to take B vitamins in the morning or early afternoon. Always adhere to the suggested daily serving.
Benfotiamine is a lipid-soluble (fat-soluble) derivative of thiamine (Vitamin B1). Its lipid solubility allows it to be more readily absorbed and retained in the body compared to water-soluble thiamine. This enhanced bioavailability contributes to its efficacy in certain applications, particularly for nerve health.
health_and_safety Safety & interactions
Generally, B vitamins are well-tolerated by most individuals. Some mild side effects might include nausea, upset stomach, or diarrhea, especially if taken on an empty stomach. Riboflavin can cause urine to turn a bright yellow color, which is a harmless effect.
Yes, certain B vitamins can interact with prescription medications. For instance, Vitamin B6 may affect drugs like levodopa, and folate can interact with anticonvulsants or methotrexate. It is advisable to consult a healthcare professional to discuss potential interactions with your specific medications.
While B vitamins are water-soluble and generally excreted by the body, excessive intake of some can lead to adverse effects. For example, very high doses of Vitamin B6 have been associated with nerve damage. It is important to adhere to recommended dosages to minimize risks.
Inositol hexaniacinate is considered a 'no-flush' form of niacin, designed to reduce the skin flushing, itching, and tingling often associated with nicotinic acid. While generally well-tolerated without these side effects, sensitive individuals might still experience mild flushing at very high doses. It offers a sustained release of niacin into the body.
Yes, high doses of biotin supplements can interfere with certain lab tests, particularly those that use biotin-streptavidin technology. This interference can lead to falsely high or low results for hormones, cardiac markers, and other analytes. It is crucial to inform your doctor and laboratory personnel about any biotin supplementation before undergoing tests.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Riboflavin | 25 mg |
Niacinamide | 50 mg NE |
Vitamin B6 | 25 mg |
Folate | 400 mcg DFE |
Vitamin B12 | 250 mcg |
Biotin | 25 mcg |
Choline | 25 mg |
Benfotiamine | 36 mg |
PABA | 25 mg |
Pantethine | 25 mg |
Inositol | 12.5 mg |
Categories
Vitamin B12 95.0
Contains 250mcg of Methylcobalamin, which is the activated and most bioavailable form of B12, ensuring optimal absorption and utilization for nerve function and red blood cell formation.
Thiamin 90.0
Features 36mg of Benfotiamine, a lipid-soluble and highly absorbable form of B1, which is superior to standard thiamine, particularly for nerve health and blood sugar support.
Vitamin B6 90.0
Provides 25mg of Pyridoxal 5-Phosphate (P-5-P), the active coenzyme form of B6, allowing for direct utilization in the body's metabolic processes without conversion.
Goals
Energy 95.0
The highly bioavailable forms, particularly Benfotiamine and activated Riboflavin, ensure more efficient cellular energy production, leading to a noticeable increase in vitality and sustained energy levels.
Brain Health 95.0
Activated Folate, Methylcobalamin, and Pyridoxal 5-Phosphate are directly utilized by the brain for crucial functions like neurotransmitter synthesis and myelin sheath maintenance, supporting optimal brain health.
Mood Support 95.0
The activated B vitamins, especially methylfolate and methylcobalamin, are pivotal for methylation processes essential for the synthesis of mood-regulating neurotransmitters like serotonin and dopamine, significantly supporting mood stability.
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