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Advanced Sleep Melatonin + 5-HTP Time Release

Natrol
4.5
(8600 ratings)
5-HTP 50 mg
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Score93

Advanced time-release tablets combining 5-HTP, melatonin, and B6 for comprehensive overnight sleep support.

How scoring works
Quantity:60 Tablet(s)(60 servings)
Goals:
Sleep Support
Mood Support
Stress Relief

Score 93

Advanced time-release tablets combining 5-HTP, melatonin, and B6 for comprehensive overnight sleep support.

How scoring works
$12.60($0.21 per serving)
Pure Formulas
$ 12.60
iHerb
$ 15.59
Amazon
$ 12.99
Walmart
$ 18.99
Vitacost
$ 15.59
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Analysis

Combining 50 mg of 5-HTP with melatonin and Vitamin B6 creates a synchronized approach for nighttime rest. Dual-layer technology allows for both immediate and gradual release to support the sleep-wake cycle throughout the night. Vitamin B6 is included to facilitate the metabolic conversion of precursors into active neurotransmitters.

A moderate dose of the primary amino acid makes this formula suitable for those who prefer gentle support over high-potency options. The time-release format addresses common issues like waking up during the night or having trouble falling back to sleep. Providing these synergistic ingredients in a single tablet simplifies a nighttime wellness routine.

Vegetable-based tablets ensure the product remains accessible to those with specific dietary preferences. A 60-serving bottle provides a two-month supply for consistent evening use. This formulation targets multiple biological pathways to support a healthy sleep-wake cycle effectively.

Who is it for
  • People who wake up during the night
  • Individuals seeking combined sleep aids
  • Users who prefer a low-dose 5-HTP
Best for
  • Maintaining sleep throughout the night
  • Facilitating easier sleep onset
  • Nighttime relaxation

Pros

  • Dual-layer time-release technology
  • Includes melatonin for sleep cycles
  • Contains Vitamin B6 for conversion
  • Vegetable-based tablet

Cons

  • Melatonin may cause morning grogginess for some
  • Lower 5-HTP dose than standalone products
  • Not suitable for daytime use

Warnings

  • Do not use when operating heavy machinery
  • Limit use to nighttime only
  • Consult a professional if taking other sleep aids

Nutrient quality

91 Highest impact

Combining 5-HTP with melatonin and Vitamin B6 provides multi-pathway support for healthy sleep and relaxation. Dual-layer technology optimizes the delivery of these nutrients, although the 50 mg dose of 5-HTP is lower than some standalone options.

Ingredient transparency

98 Highest impact

Specific amounts for 5-HTP and Vitamin B6 are clearly disclosed, though the melatonin amount should be verified on the full label. Clear instructions for nighttime use and specific delivery details contribute to a highly informative user experience.

Customer satisfaction

92 Highest impact

Strong ratings and extensive review volume suggest that the multi-ingredient approach is highly effective for sleep-related goals. Positive user feedback regarding both falling asleep and staying asleep highlights the benefits of the time-release format.

Value for money

92 Highest impact

A cost of $0.21 per serving provides good value for a specialized sleep formula with multiple active ingredients. The combination of 5-HTP, B6, and melatonin in a controlled-release tablet justifies the price point for those seeking comprehensive nighttime support.

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Goals

Impact
Highest effect
A Goal FitA Strength of SupportA CoverageA+ Formula Quality

Dual-layer tablets combine 5-HTP with melatonin for both immediate and sustained support throughout the night. This approach addresses both the initial transition to rest and the maintenance of a healthy sleep cycle.

By releasing the active building blocks gradually, the formula may help reduce nighttime awakenings for a more restorative rest. These ingredients appear well aligned for individuals seeking multi-pathway nighttime support.

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Impact
Highest effect
A- Goal FitA- Strength of SupportB CoverageA+ Formula Quality

Dual-layer time-release technology provides 50 mg of 5-HTP alongside melatonin for synchronized relaxation and sleep support. The inclusion of vitamin B6 further supports the conversion to serotonin for mood stabilization.

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Impact
Highest effect
B+ Goal FitB+ Strength of SupportB CoverageA+ Formula Quality

A dual-layer time-release tablet provides 50 mg of 5-HTP and 3 mg of melatonin to support relaxation and the sleep-wake cycle. This delivery technology is designed to help maintain steady nutrient levels for sustained emotional resilience and rest.

Naturally sourced Griffonia extract provides the 5-HTP for serotonin production, while vitamin B6 is included to assist in the metabolic conversion. The formulation targets individuals seeking gentle nighttime support and improved tolerance for amino acid supplementation.

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Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride)
10 mg
5-HTP (Griffonia simplicifolia)
50 mg
Adults 18–50 Dairy Free Women Vegetarian
Report overview
B+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyC Value
Dual-layer tablets provide a 50mg dose of 5-HTP combined with melatonin for synchronized sleep support. Gradual release technology helps maintain steady nutrient levels throughout the night.
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