Product Image

Full Spectrum Vitamin K2

4.7
★ ★ ★ ★ ★
(9353 ratings)
Vitamin K 500 mcg
Product Image
Score85
A transparent MK-4 and MK-7 combination offers broad K2 coverage and strong value, with dry delivery as its clearest weakness.
How scoring works
Capsule
Quantity:90 Capsule(s) • (90 servings)
Goals:
Bone Health
Heart Health
Anti-Aging
General Health
Cardiovascular Support

Score 85

A transparent MK-4 and MK-7 combination offers broad K2 coverage and strong value, with dry delivery as its clearest weakness.
How scoring works
$26.95($0.29 per serving)
iHerb
$ 26.99
Amazon
$ 26.95
Report prices

Analysis

The serving combines 500 mcg of MK-4 with 100 mcg of longer-acting MK-7. Using both forms gives broader K2 coverage than an MK-7-only formula.

Amounts are disclosed separately, making the active profile easy to judge. The dry capsule has no built-in lipid source, and the MK-7 is not identified as a branded or verified all-trans material.

It suits users who deliberately want both major K2 forms and already cover vitamin D and minerals elsewhere. The formula remains focused on calcium handling rather than broad heart or bone support.

Who is it for
  • Adults seeking both MK-4 and MK-7
  • People wanting a focused K2 blend
  • Users who already obtain vitamin D and minerals elsewhere
Best for
  • Dual-form vitamin K2 support
  • Combining short- and long-acting K2
  • Focused calcium-handling nutrition

Pros

  • Provides 500 mcg of MK-4
  • Supplies 100 mcg of MK-7
  • Discloses each form separately
  • Strong value for a dual-form formula

Cons

  • Dry-capsule delivery gives no built-in fat source for this fat-soluble nutrient
  • The supplied label does not identify a branded or verified all-trans MK-7 source
  • Does not include vitamin D3
  • Narrow pathway coverage

Warnings

  • Vitamin K can counteract warfarin and other vitamin K antagonist anticoagulants; use requires prescriber-guided consistency.
  • The combined 600 mcg K2 serving is substantial, so changes in intake should be deliberate.
  • Fat-malabsorption conditions can make vitamin K uptake unreliable, so response may need clinical monitoring.

Nutrient quality

90 Highest impact

Two complementary vitamin K2 forms provide broad focused coverage. The shorter-lived MK-4 form is modest relative to the total formula.

.

Ingredient transparency

84 Highest impact

Both active forms and amounts are exceptionally clear without hidden blends. Missing directions and capsule excipients are the only notable gaps.

.

Customer satisfaction

72 High impact

Aggregate satisfaction is strong and supported by an extensive evidence base. No firsthand experience details are supplied, so recurring complaints and purpose alignment cannot be checked.

.

Value for money

93 Highest impact

High-quality forms and a favorable serving position create strong value. The package compares very well with similar vitamin K products.

.
Report analysis

Goals

Bone Health
Bone Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 100 mcg

Combined MK-4 and MK-7 directly supports osteocalcin activation and calcium incorporation into bone. The 600 mcg amount is clearly disclosed and substantial for targeted K2 use.

The focused design does not provide calcium, magnesium, vitamin D, or a protein-matrix ingredient. Vitamin K2 can oppose warfarin and other vitamin K antagonists, so people using those medicines should not add it without prescriber guidance.

Study evidence
Vitamin K Supportive 78 studies
Heart Health
Heart Health
Impact
Highest effect
A Goal FitA+ Strength of SupportC CoverageA+ Formula Quality
Vitamin K · 100 mcg

MK-4 and MK-7 directly support vitamin-K-dependent proteins involved in vascular calcium handling. Their clearly disclosed combination provides strong depth with both short- and long-acting forms.

The focused formula does not address lipids, blood pressure, or cardiac energy, but it is well constructed for its chosen pathway. Vitamin K2 can counteract warfarin and other vitamin K antagonists, so use requires prescriber-guided consistency.

Study evidence
Vitamin K Mixed 62 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
B+ Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 100 mcg

MK-4 and MK-7 together supports calcium regulation relevant to vascular and skeletal aging. The active forms and amounts are clearly stated.

The formula addresses a specific healthy-aging pathway rather than broad biological aging. Vitamin K can oppose warfarin and other vitamin K antagonists, so people using those medicines should not add it without prescriber guidance.

Study evidence
Vitamin K Supportive 27 studies
General Health
General Health
Impact
Highest effect
B+ Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 100 mcg

Two clearly disclosed forms of vitamin K2 provide focused support for normal calcium handling in bones and blood vessels. MK-7 offers sustained daily activity, while MK-4 adds a complementary form.

The streamlined formula has strong relevance for people specifically seeking K2, though it does not cover the wider range of nutritional gaps associated with general health. Vitamin K2 can counteract warfarin and other vitamin K antagonists, so people using those medicines need consistent intake under prescriber guidance.

Study evidence
Vitamin K Supportive 34 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
B Goal FitA+ Strength of SupportC- CoverageA+ Formula Quality
Vitamin K · 100 mcg

Vitamin K2 supports activation of proteins that help direct calcium away from arteries and into bone. Evidence for cardiovascular outcomes is promising but less definitive than evidence for established lipid or blood-pressure interventions.

The combination of MK-4 and MK-7 provides broad K2 coverage at clearly disclosed amounts. Vitamin K can reduce warfarin’s anticoagulant effect and requires stable intake under warfarin management.

Study evidence
Vitamin K Supportive 40 studies

Ingredients

IngredientAmount per serving
Vitamin K2 (MK-4)
 500 mcg
Vitamin K2 (Menaquinone-7)
 100 mcg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Vitamin K (MK-4) · 500 mcg OverallScore87
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The formula combines 100 mcg of MK-7 with 500 mcg of MK-4 for broad K2 coverage. MK-7 reaches the clinical target, though its source is generic and the dry capsule lacks absorption guidance. Low cost creates exceptional value for the disclosed forms.

View ingredientView products
Loading alternative details
86 Performance

Vitamin K2 MK-7 (Menaquinone-7) 90 mcg

Carlson
Compared with both MK-4 and MK-7 forms of vitamin K2, the alternative provides 90 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Its focused formula offers solid routine value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
87 Performance

Vitamin K2 as MK-7 100 mcg

Healthy Origins
Compared with both MK-4 and MK-7 forms of vitamin K2, the alternative provides 100 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Vitamin K2 can reduce the effect of warfarin-type anticoagulants.
87 Performance

Vitamin K2 100 mcg

SR Sports Research
Compared with both MK-4 and MK-7 forms of vitamin K2, the alternative provides 100 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Vitamin K2 can reduce the effect of warfarin-type anticoagulants, so intake changes require prescriber guidance.
88 Budget

Vitamin K2 MK-7 100 mcg

Nutricost
The supplied serving cost is lower, while the formula provides 100 mcg of MK-7 vitamin K2. Vitamin K2 can interfere with warfarin-type anticoagulants.
89 Budget

Mega D-3 5000 IU & MK-7 180 mcg

NOW
The supplied serving cost is lower, while the formula provides 125 mcg of vitamin D3 with 180 mcg of MK-7 vitamin K2. High vitamin D remains the main dosing limitation, while the dry capsule lacks stated fat-intake guidance.
85 Budget

Vitamin K2 MenaQ7 100 mcg

AN Amazing Nutrition Amazing Formulas
The supplied serving cost is lower, while the formula provides vitamin k2. Its vitamin K can counteract warfarin and related vitamin K antagonists, so people using those medicines need clinician-directed intake.
87 Value

MK-7 Vitamin K-2 100 mcg

NOW
100 mcg of MK-7 vitamin K2 offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. Its long supply supports strong value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
87 Value

Low Dose Vitamin K2 (MK-7) 45 mcg

Life Extension
45 mcg of MK-7 vitamin K2 offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. Its focused formula offers good routine value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
86 Value

Vitamin K2 MK-7 (Menaquinone-7) 90 mcg

Carlson
90 mcg of MK-7 vitamin K2 offers a practical value trade-off because the ingredient profile remains focused for the same Vitamin K collection. Its focused formula offers solid routine value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Association of vitamin K with cardiovascular events and all-cause mortality: a systematic review and meta-analysis.
    Chen HG; Sheng LT; Zhang YB; Cao AL; Lai YW; Kunutsor SK; Jiang L; Pan A · European journal of nutrition · 2020
    Meta-analysis222,592 participants21 studies pooledHeart Health forVitamin K
  2. Comparison of concurrent treatment with vitamin K2 and risedronate compared with treatment with risedronate alone in patients with osteoporosis: Japanese Osteoporosis Intervention Trial-03.
    Tanaka S; Miyazaki T; Uemura Y; Miyakawa N; Gorai I; Nakamura T; Fukunaga M; Ohashi Y; Ohta H; Mori S; Hagino H; Hosoi T; Sugimoto T; Itoi E; Orimo H; Shiraki M · Journal of bone and mineral metabolism · 2018
    Randomized trial1,874 participantsBone Health forVitamin K
  3. Vitamin K Supplementation to Improve Vascular Stiffness in CKD: The K4Kidneys Randomized Controlled Trial.
    Witham MD; Lees JS; White M; Band M; Bell S; Chantler DJ; Ford I; Fulton RL; Kennedy G; Littleford RC; McCrea IV; McGlynn D; Panarelli M; Ralston MR; Rutherford E; Severn A; Thomson N; Traynor JP; Struthers AD; Wetherall K; Mark PB · Journal of the American Society of Nephrology : JASN · 2021
    Randomized trial159 participantsHeart Health forVitamin K
  4. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  5. Six weeks phylloquinone supplementation produces undesirable effects on blood lipids with no changes in inflammatory and fibrinolytic markers in postmenopausal women.
    Kristensen M; Kudsk J; Bügel S · European journal of nutrition · 2008
    Randomized trial31 participantsHeart Health forVitamin K
  6. Vitamin K supplementation in postmenopausal women with osteopenia (ECKO trial): a randomized controlled trial.
    Cheung AM; Tile L; Lee Y; Tomlinson G; Hawker G; Scher J; Hu H; Vieth R; Thompson L; Jamal S; Josse R · PLoS medicine · 2009
    Randomized trial440 participantsBone Health forVitamin K
  7. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsHeart Health Cardiovascular Support forVitamin K
  8. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  9. Vitamin K Supplementation for the Prevention of Cardiovascular Disease: Where Is the Evidence? A Systematic Review of Controlled Trials.
    Vlasschaert C; Goss CJ; Pilkey NG; McKeown S; Holden RM · Nutrients · 2021
    Systematic review9 studies pooledHeart Health forVitamin K
  10. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
    Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Meta-analysis6,759 participants19 studies pooledBone Health forVitamin K
  11. Vitamin K intake and all-cause and cause specific mortality.
    Zwakenberg SR; den Braver NR; Engelen AIP; Feskens EJM; Vermeer C; Boer JMA; Verschuren WMM; van der Schouw YT; Beulens JWJ · Clinical nutrition (Edinburgh, Scotland) · 2018
    Cohort study33,289 participantsHeart Health forVitamin K
  12. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  13. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  14. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsHeart Health Cardiovascular Support forVitamin K
  15. Vitamin K2 (menaquinone-7) prevents age-related deterioration of trabecular bone microarchitecture at the tibia in postmenopausal women.
    Rønn SH; Harsløf T; Pedersen SB; Langdahl BL · European journal of endocrinology · 2017
    Randomized trial148 participantsBone Health forVitamin K
  16. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsHeart Health Cardiovascular Support forVitamin K
  17. Dietary vitamin K intakes and atherosclerotic cardiovascular disease incidence: Findings from the UK biobank.
    Dupuy M; Li C; Pokharel P; Zhong L; Parmenter BH; Radavelli-Bagatini S; Dalla Via J; Linneberg A; Jakobsen J; Kühn T; Cassidy A; Hodgson JM; Lewis JR; Sim M; Bondonno NP · Atherosclerosis · 2026
    Cohort study112,111 participantsHeart Health forVitamin K
  18. Two-year randomized controlled trial of vitamin K1 (phylloquinone) and vitamin D3 plus calcium on the bone health of older women.
    Bolton-Smith C; McMurdo ME; Paterson CR; Mole PA; Harvey JM; Fenton ST; Prynne CJ; Mishra GD; Shearer MJ · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2007
    Randomized trial244 participantsBone Health forVitamin K
  19. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  20. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K
  21. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  22. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  23. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  24. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  25. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  26. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  27. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  28. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  29. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  30. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  31. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  32. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K