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Magnesium

4.8
★ ★ ★ ★ ★
(2293 ratings)
Magnesium 250 mg
Product Image
Score59
A well-absorbed magnesium core is the clear strength. The many low-dose blends add clutter rather than credible breadth.
How scoring works
Capsule
Quantity:90 Capsule(s) • (45 servings)
Goals:
General Health
Heart Health
Bone Health
Cardiovascular Support
Stress Relief
Energy

Score 59

A well-absorbed magnesium core is the clear strength. The many low-dose blends add clutter rather than credible breadth.
How scoring works
$14.99($0.33 per serving)
Vitacost
$ 16.09
iHerb
$ 14.99
Pure Formulas
$ 14.99
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Analysis

The core formula provides 250 mg of magnesium from glycinate, lysinate, and chelated sources. Those forms are generally well suited to routine systemic supplementation and are likely to be gentler than an oxide-heavy product.

Small greens, probiotic, adaptogen, antioxidant, and enzyme blends surround the magnesium core. Their pooled amounts are too low and their individual quantities are too opaque to judge as dependable secondary support.

The product works best when treated as a quality magnesium supplement rather than a comprehensive superfood or digestive formula. Two capsules per serving are reasonable, and the main mineral amount is clearly stated.

Who is it for
  • Adults wanting a well-absorbed daily magnesium blend
  • People who prefer glycinate and lysinate forms
Best for
  • Foundational magnesium replenishment
  • Muscle, nerve, and relaxation support when intake is low

Pros

  • Uses glycinate, lysinate, and chelated forms
  • Provides a practical elemental magnesium amount
  • Avoids relying on magnesium oxide

Cons

  • Numerous proprietary blends obscure individual ingredients and doses
  • The extra blends are too small to assess as meaningful support
  • No fully reacted or patented chelation standard is identified

Warnings

  • The 250 mg magnesium amount may loosen stools in sensitive users, although chelated forms are often better tolerated.
  • Magnesium can bind tetracycline or quinolone antibiotics and oral bisphosphonates, so these medicines should be taken several hours apart.
  • Impaired kidney function can reduce magnesium clearance, making a large supplemental amount less appropriate without clinical guidance.

Nutrient quality

75 High impact

Glycinate, lysinate, and chelated magnesium offer strong absorption potential. The magnesium amount is meaningful, while numerous botanical and probiotic blends are supplied only in tiny totals.

Ingredient transparency

38 Lower impact

The magnesium amount is clear, but individual ingredients inside the supporting blends have no amounts. Magnesium forms are specific, while the supporting blend names are vague marketing categories.

Customer satisfaction

71 High impact

The aggregate rating is strong and the available feedback volume gives it useful support. No specific review comments are supplied to assess recurring benefits or complaints.

Value for money

55 Moderate impact

Premium magnesium forms support value, but opaque micro-blends weaken formula quality. Many tiny supporting blends appear decorative rather than meaningfully dosed.

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Goals

Impact
Highest effect
A+ Goal FitA Strength of SupportB- CoverageC+ Formula Quality
Magnesium · 250 mg

Chelated magnesium forms provide a useful daily amount of a foundational mineral. Glycinate and lysinate support absorption, while the formula also includes many very small wellness blends.

The magnesium amount and main forms are clearly identified, giving the core ingredient good practical depth. Numerous low-dose blends broaden the label without enough detail or quantity to establish meaningful additional support.

Study evidence
Magnesium Supportive 114 studies
Impact
Highest effect
A Goal FitA+ Strength of SupportC+ CoverageC- Formula Quality
Magnesium · 250 mg

A useful magnesium amount from glycinate, lysinate, and chelated forms directly supports heart rhythm and vascular tone. The mineral contribution is clearly stated and uses absorbable forms.

Numerous tiny proprietary superfood, probiotic, adaptogen, and antioxidant blends add little cardiovascular value. The strong magnesium core is therefore wrapped in unnecessary label complexity.

Study evidence
Magnesium Supportive 158 studies
Impact
High effect
C+ Goal FitB+ Strength of SupportD CoverageA Formula Quality
Magnesium · 250 mg

A meaningful magnesium amount supports bone structure and the activation of vitamin D. Glycinate, lysinate, and chelated forms provide strong expected absorption.

The focused blend gives one mineral pathway useful depth without unrelated actives. It does not supply calcium, vitamin D, vitamin K, or protein-matrix support.

Study evidence
Magnesium Supportive 48 studies
Impact
High effect
B Goal FitA- Strength of SupportC- CoverageD Formula Quality
Magnesium · 250 mg

Chelated, glycinate, and lysinate magnesium directly support vascular tone and rhythm stability. The elemental amount reaches a useful supplemental range.

Many small greens, probiotics, adaptogens, antioxidants, and cleansing blends add no clear cardiovascular dose. The high-quality magnesium core is diluted by extensive label padding.

Study evidence
Magnesium Supportive 123 studies
Impact
High effect
B Goal FitA Strength of SupportC- CoverageF Formula Quality
Magnesium · 250 mg

Chelated magnesium forms provide a meaningful amount for nervous-system and muscle relaxation. Glycinate and lysinate strengthen absorption potential.

Numerous greens, probiotic, antioxidant, and adaptogen blends are supplied in tiny pooled amounts. Those additions add label breadth without credible stress-relief depth.

Study evidence
Magnesium Supportive 13 studies
Energy
Impact
High effect
B Goal FitA Strength of SupportD+ CoverageD- Formula Quality
Magnesium · 250 mg

Chelated magnesium forms provide a useful elemental amount for ATP-dependent metabolism. Glycinate and lysinate improve the mineral foundation.

A long series of tiny proprietary blends adds greens, probiotics, adaptogens, antioxidants, and enzymes without meaningful individual doses. The strong magnesium core is undermined by extensive label dressing around it.

Study evidence
Magnesium Supportive 4 studies

Ingredients

IngredientAmount per serving
Magnesium (Magnesium Chelate, Magnesium Glycinate, Magnesium Lysinate)
250 mg
Nature's C Veggie Berry Blend
73 mg
Organic Alkalizing Green Juice Powders
65 mg
Organic Aqua Superfoods
47 mg
Probiotics
31 mg
Defense & Energy Adaptogens
10 mg
Stress & Energy Adaptogens (Extracts)
10 mg
Super Antioxidants
5 mg
Cleansing & Tonic Support
5 mg
GingerZyme Extract
5 mg
Gluten Free Adults 18–50 Vegan Vegetarian
Report overview
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

Glycinate, lysinate, and chelated magnesium provide strong absorption potential at a useful daily amount. The label clearly states the magnesium yield, but it does not identify a patented or fully reacted chelate. The low serving cost supports strong value for a premium-form blend.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
    van der Schoot A; Creedon A; Whelan K; Dimidi E · Neurogastroenterology and motility · 2023
    Meta-analysis787 participants8 studies pooledDigestive Health forMagnesium
  2. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  3. Effect of the laxative magnesium oxide on gastrointestinal functional recovery in fast-track colonic resection: a double-blind, placebo-controlled randomized study.
    Andersen J; Christensen H; Pachler JH; Hallin M; Thaysen HV; Kehlet H · Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2012
    Randomized trial49 participantsDigestive Health forMagnesium
  4. Lactobacillus reuteri DSM 17938 and Magnesium Oxide in Children with Functional Chronic Constipation: A Double-Blind and Randomized Clinical Trial.
    Kubota M; Ito K; Tomimoto K; Kanazaki M; Tsukiyama K; Kubota A; Kuroki H; Fujita M; Vandenplas Y · Nutrients · 2020
    Randomized trial60 participantsDigestive Health forMagnesium
  5. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  6. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  7. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  8. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  9. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  10. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  11. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  12. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  13. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  14. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  15. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  16. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  17. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  18. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  19. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  20. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  21. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  22. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  23. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  24. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  25. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  26. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  27. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  28. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  29. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  30. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  31. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  32. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  33. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  34. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  35. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  36. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  37. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  38. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  39. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  40. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  41. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium