Product Image

Biotin Forte 3 mg Biotin with Zinc

Nature's Way
4.7
★ ★ ★ ★ ★
(2483 ratings)
Vitamin B6 25 mg
Niacin 40 mg
Biotin 3000 mcg
Zinc 30 mg
Riboflavin 10 mg
Thiamin 10 mg
Product Image
Score76
A strong-value biotin formula with useful supporting nutrients, but high zinc and vitamin B6 make it more aggressive than a simple beauty supplement.
How scoring works
Quantity:60 Tablet(s) • (60 servings)
Goals:
General Health
Testosterone Support
Immunity
Hair Health
Nail Health

Score 76

A strong-value biotin formula with useful supporting nutrients, but high zinc and vitamin B6 make it more aggressive than a simple beauty supplement.
How scoring works

Also available as

1 option
5000 mcg • 60 Tablet(s) servings 5000 mcg • 60 Tablet(s) • 60 servings $11.73 ($0.19 per serving)
$9.69($0.16 per serving)
iHerb
$ 9.89
Amazon
$ 9.89
Pure Formulas
$ 9.83
Vitacost
$ 10.89
Vitacost
$ 10.89
Walmart
$ 23.00
iHerb
$ 9.69
Report prices

Analysis

Biotin provides the main hair and nail focus, supported by zinc, vitamin C, folate, and several B vitamins. The single-tablet serving is convenient and economically accessible.

Zinc sulfate is less gentle than some chelated forms, and its amount is high enough to cause nausea or disrupt copper balance with prolonged use. Vitamin B6 and niacinamide also add more potency than the core beauty purpose requires.

The formula may fit adults seeking a focused, inexpensive biotin product with added nutrients. Users undergoing thyroid, hormone, or cardiac testing need to disclose biotin use because it can distort some results.

Who is it for
  • Adults seeking a low-cost biotin supplement
  • People wanting zinc and vitamin C with biotin
Best for
  • Hair and nail nutrient support
  • Single-tablet beauty supplementation

Pros

  • High biotin amount
  • Includes zinc and vitamin C
  • Low serving cost

Cons

  • Zinc sulfate can be hard on the stomach
  • Vitamin B6 is high for routine use
  • No copper to balance high zinc

Warnings

  • The 3,000 mcg biotin amount can interfere with thyroid, hormone, and cardiac laboratory tests; disclose use before testing.
  • The 30 mg zinc amount may cause nausea and can impair copper status with prolonged use.
  • Long-term intake of 25 mg vitamin B6 may contribute to tingling or other nerve symptoms.

Nutrient quality

64 Moderate impact

Calcium pantothenate is useful, while zinc sulfate, cyanocobalamin, and pyridoxine hydrochloride are ordinary forms, and biotin, zinc, vitamin C, and several B vitamins are meaningfully dosed. Zinc, vitamin B6, and niacin are aggressive, while high biotin can interfere with some laboratory tests, while the compact active formula is not padded with unrelated ingredients.

Ingredient transparency

81 Highest impact

Specific amounts are listed for every supplied active ingredient. No proprietary blend hides active doses, while inactive tablet ingredients are not provided.

Customer satisfaction

71 High impact

The supplied aggregate satisfaction metric is favorable, and the large amount of aggregate feedback makes the metric highly stable. No review excerpts were provided, so recurring complaints and purpose-specific experiences cannot be checked.

Value for money

86 Highest impact

The focused formula and low serving cost support good value, despite an overly aggressive nutrient load. One tablet provides substantial targeted doses at a low cost, while the formula avoids low-value specialty extras.

Report analysis

Goals

General Health
General Health
Impact
High effect
B+ Goal FitB Strength of SupportB+ CoverageB Formula Quality
Folate · 800 mcg DFEVitamin B12 · 10 mcgZinc · 30 mgVitamin C · 200 mg

The combination covers several B vitamins, vitamin C, biotin, and zinc, giving it broader nutritional relevance than a simple beauty formula. Zinc sulfate and cyanocobalamin are serviceable but not preferred forms.

Most amounts are substantial, yet the high zinc exposure has no copper balance for prolonged daily use. The formula may suit a targeted short-term need better than indefinite general supplementation.

Study evidence
Folate Supportive 80 studies
Vitamin C Supportive 56 studies
Zinc Supportive 60 studies
Testosterone Support
Testosterone Support
Impact
High effect
B Goal FitC+ Strength of SupportC+ CoverageC Formula Quality
Zinc · 30 mg

Zinc and vitamin B6 provide relevant cofactors for testosterone synthesis and hormonal regulation. Zinc has strong deficiency-correction evidence, while direct benefits are less reliable in zinc-replete users.

The 30 mg zinc and 25 mg vitamin B6 amounts are substantial for daily support. Zinc sulfate has weaker tolerance and absorption than preferred organic forms, and B6 is not supplied as active P-5-P.

Study evidence
Zinc Disputed 7 studies
Immunity
Immunity
Impact
High effect
B+ Goal FitC+ Strength of SupportC+ CoverageD+ Formula Quality
Vitamin C · 200 mgZinc · 30 mg

Zinc and vitamin C support immune-cell function and antioxidant defenses, but the product is built mainly around biotin and B vitamins. The 30 mg zinc amount is substantial, while zinc sulfate is less absorbable and may be harder on the stomach.

Several nutrients broaden coverage, yet vitamin C remains below the preferred immune target and no copper balances long-term zinc use. The 3,000 mcg biotin amount can interfere with thyroid, hormone, and cardiac laboratory tests, so it should be disclosed before testing.

Study evidence
Vitamin C Supportive 53 studies
Zinc Supportive 73 studies
Hair Health
Hair Health
Impact
High effect
C+ Goal FitB- Strength of SupportC+ CoverageC Formula Quality
Biotin · 3000 mcgZinc · 30 mgVitamin C · 200 mg

Biotin, zinc, vitamin C, and B vitamins cover several nutritional factors involved in follicle function. Hair benefits remain most likely when one of these nutrients is inadequate.

The broad label discloses all amounts, although zinc sulfate and cyanocobalamin are less preferred forms. High-dose biotin can distort laboratory tests, while long-term zinc and vitamin B6 intake at these amounts may raise copper-depletion or nerve-symptom concerns.

Study evidence
Biotin Supportive 4 studies
Vitamin C Mixed 5 studies
Zinc Supportive 22 studies
Nail Health
Nail Health
Impact
High effect
C Goal FitC Strength of SupportB- CoverageC+ Formula Quality
Biotin · 3000 mcg

Biotin provides a relevant route to nail health. The disclosed amount appears meaningful for that focused role.

Several complementary pathways broaden the formula. Biotin Forte 3 mg Biotin with Zinc is best viewed as targeted support rather than proof of a clinical benefit.

Study evidence
Biotin Supportive 8 studies
Zinc No effect 1 study
Skin Health
Skin Health
Impact
Moderate effect
C- Goal FitC+ Strength of SupportC CoverageD+ Formula Quality
Zinc · 30 mgVitamin C · 200 mg

Vitamin C and zinc support collagen formation, wound repair, and normal skin integrity, while biotin is mainly useful when intake is inadequate. Evidence does not support very high biotin as a reliable skin enhancer in people without deficiency.

The formula provides meaningful vitamin C and zinc but uses less appealing zinc sulfate and adds many unrelated B vitamins. Biotin at 3,000 mcg can interfere with some thyroid and cardiac blood tests, so the testing clinician or laboratory should be told before testing.

Study evidence
Biotin Supportive 10 studies
Vitamin C Supportive 53 studies
Zinc Supportive 66 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
 200 mg
Thiamine (Vitamin B1)
 10 mg
Riboflavin (Vitamin B2)
 10 mg
Niacin (Niacinamide)
 40 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 25 mg
Folate
800 mcg DFE
Vitamin B12 (Cyanocobalamin)
 10 mcg
Biotin
3000 mcg
Pantothenic Acid (Calcium D-Pantothenate)
 10 mg
Zinc (Zinc Sulfate)
 30 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
Vitamin B6 (Pyridoxine Hydrochloride) · 25 mg OverallScore86
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Pyridoxine hydrochloride is paired with riboflavin, which may support conversion, but active P-5-P is absent. The B6 dose is well aligned and one tablet keeps use simple. Cost efficiency is favorable for the broad vitamin-and-mineral formula.

View ingredientView products
Niacin (Niacinamide) · 40 mg OverallScore78
B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyC Value

Niacinamide is clearly disclosed at an amount suited to a multi-nutrient formula. The standard tablet lacks special delivery technology and does not explicitly identify itself as no flush. Its moderate serving cost is reasonable for the broader vitamin, biotin, and zinc profile, though niacin is not the formula's main focus.

View ingredientView products
Biotin · 3000 mcg OverallScore73
B- Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyD+ Value

Biotin is clearly disclosed at a useful targeted amount alongside zinc and several B vitamins. The tablet is acceptable, although the label does not verify the active d-isomer. The normalized cost is moderate, and the biotin amount may warrant disclosure before laboratory testing.

View ingredientView products
Loading alternative details
85 Performance

B-Complex Plus

Pure Encapsulations
<p>Methylfolate, methylcobalamin, pyridoxal 5-phosphate, and activated riboflavin provide stronger forms and a more balanced B6 amount than the original. It offers broad nutritional support but is less targeted to hair and nails because it lacks the original’s high biotin and zinc combination.</p>
77 Performance

Vitamin B Complex

California Gold Nutrition
<p>Active riboflavin and B6 improve form quality while folate and pantothenic acid broaden the original’s B-vitamin base. Duplicate entries make actual totals unclear, and the formula does not match the original’s targeted zinc amount.</p>
79 Performance

B Complex Plus

Seeking Health
<p>Active riboflavin, B6, and B12 forms create a more refined B-complex than the original’s conventional vitamin forms. Ambiguous niacin disclosure and the absence of targeted zinc make it less specific for hair and nail support.</p>
80 Budget

Super Vitamin B-Complex

Spring Valley
<p>Broad B-vitamin coverage comes at much lower recurring cost with measured amounts and a simple formula. Chemical forms are missing and the product is less hair-focused because the supplied data do not establish a comparable high biotin and zinc combination.</p>
78 Budget

B-50 Complex

21st Century
<p>A long supply provides core B-vitamin support at lower recurring cost than the biotin-and-zinc formula. Conventional forms and elevated B6 reduce long-term suitability, while the product does not provide the same targeted biotin or zinc amounts.</p>
84 Budget

Super B-Complex with Folic Acid plus Vitamin C

Nature's Bounty
<p>A broad, inexpensive B-complex retains vitamin C and biotin with less aggressive B6 and zinc exposure than the original. Basic forms remain a limitation, and biotin can still interfere with thyroid, cardiac, and hormone laboratory tests.</p>
76 Value

Biotin Forte

Nature's Way
<p>High-dose biotin plus vitamin C and supporting B vitamins closely preserves the original’s hair, skin, and nail focus without the high zinc amount. Recurring cost is slightly higher, while biotin can still distort laboratory tests and B6 remains elevated.</p>
78 Value

Vitamins Only

Solgar
<p>Broad antioxidant and energy-metabolism vitamin coverage provides useful ingredient breadth at a reasonable recurring cost. High B6 and an unusual pantothenic-acid unit weaken confidence, while the formula is less targeted because it does not reproduce the original’s high biotin and zinc pairing.</p>
74 Value

Advanced Absorption Mega B-Complex

Irwin Naturals
<p>Methylcobalamin and a broad B-vitamin profile offer substantial coverage for the cost. Duplicate entries and elevated B6 reduce clarity and long-term balance, while the lack of targeted zinc makes it less specific for hair and nail support.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health Nail Health Skin Health forBiotin
  2. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  3. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  4. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid function tests, zinc, copper, biotin, and selenium levels.
    Durusu Turkoglu IN; Turkoglu AK; Soylu S; Gencer G; Duman R · Journal of cosmetic dermatology · 2024
    Case-control study180 participantsHair Health forZinc
  5. Biotin for the treatment of nail disease: what is the evidence?
    Lipner SR; Scher RK · The Journal of dermatological treatment · 2018
    Narrative reviewNail Health forBiotin
  6. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forZinc Nail Health forBiotin
  7. Comparison of efficacy of folic acid and silymarin in the management of antiepileptic drug induced liver injury: a randomized clinical trial.
    Asgarshirazi M; Shariat M; Sheikh M · Hepatobiliary & pancreatic diseases international : HBPD INT · 2018
    Randomized trial55 participantsDetoxification forFolate
  8. Homocysteine, folate, and nonalcoholic fatty liver disease: a systematic review with meta-analysis and Mendelian randomization investigation.
    Yuan S; Chen J; Dan L; Xie Y; Sun Y; Li X; Larsson SC · The American journal of clinical nutrition · 2022
    Meta-analysis30,368 participants22 studies pooledDetoxification forFolate
  9. Serum folate levels and urinary arsenic methylation profiles in the US population: NHANES, 2003-2012.
    Zhang X; Xu X; Zhong Y; Power MC; Taylor BD; Carrillo G · Journal of exposure science & environmental epidemiology · 2020
    Cross-sectional study11,016 participantsDetoxification forFolate
  10. Association between serum folate levels and blood concentrations of cadmium and lead in US adults.
    Wu Z; Hu H; Wang C; Wu J; Xiong Y; Fu Y; Cheng X; Su H; Li P · Environmental science and pollution research international · 2022
    Cross-sectional study15,501 participantsDetoxification forFolate
  11. Effects of Folic Acid Supplementation on Liver Enzymes, Lipid Profile, and Insulin Resistance in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Trial.
    Molaqanbari MR; Zarringol S; Talari HR; Taghizadeh M; Bahmani F; Mohtashamian A; Ebrahimzadeh A; Sharifi N · Advanced biomedical research · 2023
    Randomized trial66 participantsDetoxification forFolate
  12. Vitamin C supplementation ameliorates liver function profile and antiviral treatment response in Hepatitis C patients.
    Nayila I; Javed MS; Khan MA; Hussain G; Raza Naqvi SA; Ali S; Jabeen Z; Shahnawaz S; Akram R; Iman T; Hassan Dogar MZ; Malik SA · Pakistan journal of pharmaceutical sciences · 2022
    Non-randomized trial200 participantsDetoxification forVitamin C
  13. Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress.
    Alleva R; Di Donato F; Strafella E; Staffolani S; Nocchi L; Borghi B; Pignotti E; Santarelli L; Tomasetti M · The British journal of nutrition · 2012
    Non-randomized trial46 participantsDetoxification forVitamin C
  14. Dietary Vitamin C Intake Is Associated With Improved Liver Function and Glucose Metabolism in Chinese Adults.
    Luo X; Zhang W; He Z; Yang H; Gao J; Wu P; Ma ZF · Frontiers in nutrition · 2022
    Observational study8,307 participantsDetoxification forVitamin C
  15. Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection.
    Trepanier LA; Yoder AR; Bajad S; Beckwith MD; Bellehumeur JL; Graziano FM · Journal of acquired immune deficiency syndromes (1999) · 2005
    Observational studyDetoxification forVitamin C
  16. Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso.
    Lavergne SN; Kurian JR; Bajad SU; Maki JE; Yoder AR; Guzinski MV; Graziano FM; Trepanier LA · Toxicology · 2006
    Clinical trial53 participantsDetoxification forVitamin C
  17. [Therapy of Wilson disease].
    Smolarek C; Stremmel W · Zeitschrift fur Gastroenterologie · 1999
    Narrative reviewDetoxification forZinc
  18. Efficacy of Zinc Supplement in Minimal hepatic Encephalopathy: A prospective, Randomized Controlled Study (Zinc-MHE Trial).
    Janyajirawong R; Vilaichone RK; Sethasine S · Asian Pacific journal of cancer prevention : APJCP · 2021
    Randomized trial69 participantsDetoxification forZinc
  19. Effect of zinc on liver cirrhosis with hyperammonemia: a preliminary randomized, placebo-controlled double-blind trial.
    Katayama K; Saito M; Kawaguchi T; Endo R; Sawara K; Nishiguchi S; Kato A; Kohgo H; Suzuki K; Sakaida I; Ueno Y; Habu D; Ito T; Moriwaki H; Suzuki K · Nutrition (Burbank, Los Angeles County, Calif.) · 2015
    Randomized trial18 participantsDetoxification forZinc
  20. Effects of low dose zinc supplementation on biochemical markers in non-alcoholic cirrhosis: a randomized clinical trial.
    Somi MH; Rezaeifar P; Ostad Rahimi A; Moshrefi B · Archives of Iranian medicine · 2012
    Randomized trial60 participantsDetoxification forZinc
  21. Correlation of Serum Zinc Levels with Hepatic Encephalopathy Severity in Patients with Decompensated Liver Cirrhosis: A Prospective Observational Study from Egypt.
    Semeya AA; Elgamal R; Othman AAA · Biological trace element research · 2025
    Observational study200 participantsDetoxification forZinc
  22. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  23. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  24. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  25. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  26. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  27. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  28. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  29. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  30. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  31. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  32. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  33. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  34. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  35. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  36. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  37. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  38. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  39. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  40. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  41. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  42. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  43. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  44. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  45. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  46. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  47. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health Skin Health forBiotin
  48. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  49. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  50. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  51. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  52. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  53. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  54. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  55. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  56. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  57. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  58. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  59. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  60. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  61. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  62. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  63. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  64. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  65. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  66. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  67. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  68. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Boost forBiotin
  69. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Boost forBiotin
  70. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Boost forBiotin
  71. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Boost forBiotin
  72. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Boost forBiotin
  73. The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects: A phase 2 randomized, placebo-controlled trial with a multi-arm, parallel-group design.
    Karandish M; Mozaffari-Khosravi H; Mohammadi SM; Cheraghian B; Azhdari M · Phytotherapy research : PTR · 2021
    Randomized trial84 participantsMetabolism Boost forZinc
  74. Relationship between zinc and glucose metabolism in Japanese adults.
    Suka M; Tsuruta H; Takao T; Yanagisawa H · Diabetology international · 2026
    Cross-sectional study533 participantsMetabolism Boost forZinc
  75. Zinc and the Innovative Zinc-α2-Glycoprotein Adipokine Play an Important Role in Lipid Metabolism: A Critical Review.
    Banaszak M; Górna I; Przysławski J · Nutrients · 2021
    Narrative reviewMetabolism Boost forZinc
  76. Capsaicin and Zinc Signalling Pathways as Promising Targets for Managing Insulin Resistance and Type 2 Diabetes.
    Ferdowsi PV; Ahuja KDK; Beckett JM; Myers S · Molecules (Basel, Switzerland) · 2023
    Narrative reviewMetabolism Boost forZinc
  77. Zinc and Diabetes: A Connection between Micronutrient and Metabolism.
    Ahmad R; Shaju R; Atfi A; Razzaque MS · Cells · 2024
    Narrative reviewMetabolism Boost forZinc
  78. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy.
    Colombo VE; Gerber F; Bronhofer M; Floersheim GL · Journal of the American Academy of Dermatology · 1991
    Other32 participantsNail Health forBiotin
  79. Treatment of brittle nail with a hydroxypropyl chitosan-based lacquer, alone or in combination with oral biotin: A randomized, assessor-blinded trial.
    Chiavetta A; Mazzurco S; Secolo MP; Tomarchio G; Milani M · Dermatologic therapy · 2020
    Randomized trial50 participantsNail Health forBiotin
  80. Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters.
    Aksac SE; Bilgili SG; Yavuz GO; Yavuz IH; Aksac M; Karadag AS · International journal of dermatology · 2021
    Non-randomized trial60 participantsSkin Health forBiotin
  81. Generalized seborrhoeic dermatitis. Clinical and therapeutic data of 25 patients.
    Messaritakis J; Kattamis C; Karabula C; Matsaniotis N · Archives of disease in childhood · 1976
    Non-randomized trial25 participantsSkin Health forBiotin
  82. Holocarboxylase synthetase deficiency: novel clinical and molecular findings.
    Tammachote R; Janklat S; Tongkobpetch S; Suphapeetiporn K; Shotelersuk V · Clinical genetics · 2010
    Case series4 participantsSkin Health forBiotin
  83. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  84. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  85. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  86. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  87. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  88. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  89. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  90. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  91. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  92. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forZinc
  93. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  94. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  95. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  96. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  97. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  98. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  99. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  100. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  101. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  102. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C
  103. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  104. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  105. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  106. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  107. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc