Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Anti-Inflammatory Efficacy of Curcumin as an Adjunct to Non-Surgical Periodontal Treatment: A Systematic Review and Meta-Analysis.
Zhang Y; Huang L; Zhang J; De Souza Rastelli AN; Yang J; Deng D · Frontiers in pharmacology · 2024
Meta-analysis846 participants18 studies pooledflagAnti-Inflammatory Support forscienceCurcumin
- Effects of curcumin on dyslipidemia and body mass index in metabolic disorders: a systematic review and meta-analysis.
Fang F; Qin D; Li Y; Liu F; Wu J · Frontiers in nutrition · 2025
Meta-analysis662 participants11 studies pooledflagCardiovascular Support forscienceCurcumin
- Effect of fish oil supplement in maintenance hemodialysis patients: a systematic review and meta-analysis of published randomized controlled trials.
He L; Li MS; Lin M; Zhao TY; Gao P · European journal of clinical pharmacology · 2016
Meta-analysis916 participants13 studies pooledflagAnti-Inflammatory Support forscienceFish Oil
- Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.
Ma B; Lu J; Kang T; Zhu M; Xiong K; Wang J · Nutrition research (New York, N.Y.) · 2022
Meta-analysis380 participants12 studies pooledflagAnti-Inflammatory Support forscienceAstaxanthin
- Curcumin and/or omega-3 polyunsaturated fatty acids supplementation reduces insulin resistance and blood lipids in individuals with high risk of type 2 diabetes: a randomised controlled trial.
Thota RN; Acharya SH; Garg ML · Lipids in health and disease · 2019
Randomized trial64 participantsflagMetabolism Boost forscienceCurcumin
- Lipid profile and glucose changes after supplementation with astaxanthin: a systematic review and meta-analysis of randomized controlled trials.
Ursoniu S; Sahebkar A; Serban MC; Banach M · Archives of medical science : AMS · 2015
Meta-analysis280 participants7 studies pooledflagCardiovascular Support forscienceAstaxanthin
- Effects of Omega-3 Fatty Acids Intake on Lipid Metabolism and Plaque Volume in Patients With Coronary Heart Disease: A Systematic Review and Dose-Response Meta-Analysis of Randomized Clinical Trials.
Zhang C; Xie Y; Zhou J; Zhang C; Xiang Q; Zhong Y; Xiao J; Feng J; Liao B; Chen X; Deng L · Food science & nutrition · 2025
Meta-analysis2,061 participants23 studies pooledflagMetabolism Boost forscienceOmega-3
- Effect of Losartan and Fish Oil on Plasma IL-6 and Mobility in Older Persons. The ENRGISE Pilot Randomized Clinical Trial.
Pahor M; Anton SD; Beavers DP; Cauley JA; Fielding RA; Kritchevsky SB; Leeuwenburgh C; Lewis KH; Liu CK; Lovato LC; Lu J; Manini TM; McDermott MM; Miller ME; Newman AB; Radziszewska B; Stowe CL; Tracy RP; Walkup MP; Wu SS; Ambrosius WT · The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
Randomized trial289 participantsflagJoint Health forscienceOmega-3
- Efficacy of Extracts of Oleogum Resin of Boswellia in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis.
Dalmonte T; Andreani G; Rudelli C; Isani G · Phytotherapy research : PTR · 2024
Meta-analysis1,185 participants13 studies pooledflagJoint Health forscienceBoswellia
- Impact of Supplementation with Curcuminoids on Systemic Inflammation in Patients with Knee Osteoarthritis: Findings from a Randomized Double-Blind Placebo-Controlled Trial.
Rahimnia AR; Panahi Y; Alishiri G; Sharafi M; Sahebkar A · Drug research · 2016
Randomized trial40 participantsflagJoint Health forscienceCurcumin
- Randomized, placebo-controlled, double-blind trial of Boswellia serrata in maintaining remission of Crohn's disease: good safety profile but lack of efficacy.
Holtmeier W; Zeuzem S; Preiss J; Kruis W; Böhm S; Maaser C; Raedler A; Schmidt C; Schnitker J; Schwarz J; Zeitz M; Caspary W · Inflammatory bowel diseases · 2011
Randomized trial108 participantsflagAnti-Inflammatory Support forscienceBoswellia
- Astaxanthin supplement improves clinical outcomes, quality of life, and inflammatory factors in patients with rheumatoid arthritis: a randomized clinical trial.
Grigorian A; Tabatabaeyan A; Salesi M; Feizi A; Ahmadi AR; Kafeshani M · Food & function · 2025
Randomized trial60 participantsflagJoint Health flagAnti-Inflammatory Support forscienceAstaxanthin
- A systematic review and meta-analysis of randomized controlled trials investigating the effects of curcumin on blood lipid levels.
Sahebkar A · Clinical nutrition (Edinburgh, Scotland) · 2014
Meta-analysis223 participants5 studies pooledflagCardiovascular Support forscienceCurcumin
- Oral turmeric/curcumin effects on inflammatory markers in chronic inflammatory diseases: A systematic review and meta-analysis of randomized controlled trials.
White CM; Pasupuleti V; Roman YM; Li Y; Hernandez AV · Pharmacological research · 2020
Meta-analysis1,344 participants19 studies pooledflagAnti-Inflammatory Support forscienceCurcumin
- Omega-3 polyunsaturated fatty acids and the treatment of rheumatoid arthritis: a meta-analysis.
Lee YH; Bae SC; Song GG · Archives of medical research · 2013
Meta-analysis10 studies pooledflagJoint Health forscienceOmega-3
- Astaxanthin has no effect on arterial stiffness, oxidative stress, or inflammation in renal transplant recipients: a randomized controlled trial (the XANTHIN trial).
Coombes JS; Sharman JE; Fassett RG · The American journal of clinical nutrition · 2016
Randomized trial61 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- No effect of fish oil supplementation on serum inflammatory markers and their interrelationships: a randomized controlled trial in healthy, middle-aged individuals.
Pot GK; Brouwer IA; Enneman A; Rijkers GT; Kampman E; Geelen A · European journal of clinical nutrition · 2010
Randomized trial77 participantsflagAnti-Inflammatory Support forscienceFish Oil
- The Oral Administration of Highly-Bioavailable Curcumin for One Year Has Clinical and Chondro-Protective Effects: A Randomized, Double-Blinded, Placebo-Controlled Prospective Study.
Nakagawa Y; Mori K; Yamada S; Mukai S; Hirose A; Nakamura R · Arthroscopy, sports medicine, and rehabilitation · 2022
Randomized trial50 participantsflagJoint Health forscienceCurcumin
- Double-blind trial of solid lipid Boswellia serrata particles (SLBSP) vs. standardized Boswellia serrata gum extract (BSE) for osteoarthritis of knee.
Kulkarni PD; Damle ND; Singh S; Yadav KS; Ghante MR; Bhaskar VH; Hingorani L; Gota VS · Drug metabolism and personalized therapy · 2021
Randomized trialflagAnti-Inflammatory Support forscienceBoswellia
- The association of organophosphate flame retardants (OPFRs) exposure on omega-3 fatty acids metabolism: evidence derived from the United States general population.
Hsu TH; Pan HY; Tsai KF; Kung CT; Huang WT; You HL; Li SH; Wang CC; Lee WC; Cheng FJ · Toxicology research · 2025
Cross-sectional study1,350 participantsflagMetabolism Boost forscienceOmega-3
- A standardized Boswellia serrata extract shows improvements in knee osteoarthritis within five days-a double-blind, randomized, three-arm, parallel-group, multi-center, placebo-controlled trial.
Majeed A; Majeed S; Satish G; Manjunatha R; Rabbani SN; Patil NVP; Mundkur L · Frontiers in pharmacology · 2024
Randomized trial105 participantsflagJoint Health flagAnti-Inflammatory Support forscienceBoswellia
- Curcumin extract improves beta cell functions in obese patients with type 2 diabetes: a randomized controlled trial.
Yaikwawong M; Jansarikit L; Jirawatnotai S; Chuengsamarn S · Nutrition journal · 2024
Randomized trial272 participantsflagMetabolism Boost forscienceCurcumin
- Astaxanthin, a natural antioxidant, lowers cholesterol and markers of cardiovascular risk in individuals with prediabetes and dyslipidaemia.
Ciaraldi TP; Boeder SC; Mudaliar SR; Giovannetti ER; Henry RR; Pettus JH · Diabetes, obesity & metabolism · 2023
Randomized trial34 participantsflagCardiovascular Support forscienceAstaxanthin
- Dietary fats and prevention of type 2 diabetes.
Risérus U; Willett WC; Hu FB · Progress in lipid research · 2010
Narrative reviewflagMetabolism Boost forscienceOmega-3
- A Standardized Boswellia serrata Extract Improves Knee Joint Function and Cartilage Morphology in Human Volunteers with Mild to Moderate Osteoarthritis in a Randomized Placebo-Controlled Study.
Kumar B; Ghaytidak AB; Pandey AK; Somepalli RR; Sarda P; Raychaudhuri SP; Rokkam MP · Journal of the American Nutrition Association · 2025
Randomized trial80 participantsflagJoint Health flagAnti-Inflammatory Support forscienceBoswellia
- The anti-inflammatory and antioxidant effects of astaxanthin as an adjunctive therapy in community-acquired pneumonia: a randomized controlled trial.
Youssef FM; Ateyya H; Hanna Samy AE; Elmokadem EM · Frontiers in pharmacology · 2025
Randomized trial80 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis.
Zeng L; Yu G; Hao W; Yang K; Chen H · Bioscience reports · 2022
Meta-analysis1,621 participants15 studies pooledflagJoint Health forscienceCurcumin
- Nano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with non-alcoholic fatty liver disease (NAFLD): a double-blind randomized placebo-controlled clinical trial.
Jazayeri-Tehrani SA; Rezayat SM; Mansouri S; Qorbani M; Alavian SM; Daneshi-Maskooni M; Hosseinzadeh-Attar MJ · Nutrition & metabolism · 2024
Randomized trial84 participantsflagCardiovascular Support flagAnti-Inflammatory Support forscienceCurcumin
- Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial.
Stonehouse W; Benassi-Evans B; Bednarz J; Vincent AD; Hall S; Hill CL · The American journal of clinical nutrition · 2022
Randomized trial235 participantsflagJoint Health forscienceOmega-3
- Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials.
Qin S; Huang L; Gong J; Shen S; Huang J; Ren H; Hu H · Nutrition journal · 2018
Meta-analysis649 participants7 studies pooledflagCardiovascular Support forscienceCurcumin
- Clinical Benefits of Boswellia Serrata (BOSMAX®) in Early Knee Osteoarthritis: A Randomized, Placebo-Controlled, Double-Blind Study.
Jayaram M; Kim J; Baek KS; Jung H; Kim J; M K P; T S C; H B S; Ramaiah V; S P · Journal of medicinal food · 2025
Randomized trial150 participantsflagAnti-Inflammatory Support forscienceBoswellia
- Effects of phytosomal curcumin on anthropometric parameters, insulin resistance, cortisolemia and non-alcoholic fatty liver disease indices: a double-blind, placebo-controlled clinical trial.
Cicero AFG; Sahebkar A; Fogacci F; Bove M; Giovannini M; Borghi C · European journal of nutrition · 2021
Randomized trial80 participantsflagMetabolism Boost forscienceCurcumin
- Effects of fish oil supplementation on biomarkers of vascular endothelial function in middle-aged and older adults: a randomized controlled trial.
Quan C; Tang W; Qin Y; Nian Z; Li Z; Mao L · Food & function · 2026
Randomized trial240 participantsflagAnti-Inflammatory Support forscienceFish Oil
- Effects of Astaxanthin supplementation on selected metabolic parameters, anthropometric indices, Sirtuin1 and TNF-α levels in patients with coronary artery disease: A randomized, double-blind, placebo-controlled clinical trial.
Heidari M; Chaboksafar M; Alizadeh M; Sohrabi B; Kheirouri S · Frontiers in nutrition · 2023
Randomized trial50 participantsflagCardiovascular Support forscienceAstaxanthin
- Oral herbal therapies for treating osteoarthritis.
Cameron M; Chrubasik S · The Cochrane database of systematic reviews · 2015
Meta-analysis5,980 participants49 studies pooledflagJoint Health forscienceBoswellia
- A Meta-Analysis of the Impact of Nutritional Supplementation on Osteoarthritis Symptoms.
Mathieu S; Soubrier M; Peirs C; Monfoulet LE; Boirie Y; Tournadre A · Nutrients · 2022
Meta-analysis1,438 participants12 studies pooledflagJoint Health forscienceCurcumin
- A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee.
Majeed M; Majeed S; Narayanan NK; Nagabhushanam K · Phytotherapy research : PTR · 2019
Randomized trial48 participantsflagAnti-Inflammatory Support flagJoint Health forscienceBoswellia
- Curcumin Nanomicelle Improves Lipid Profile, Stress Oxidative Factors and Inflammatory Markers in Patients Undergoing Coronary Elective Angioplasty; A Randomized Clinical Trial.
Helli B; Gerami H; Kavianpour M; Heybar H; Hosseini SK; Haghighian HK · Endocrine, metabolic & immune disorders drug targets · 2022
Randomized trial90 participantsflagCardiovascular Support flagAnti-Inflammatory Support forscienceCurcumin
- Are curcuminoids effective C-reactive protein-lowering agents in clinical practice? Evidence from a meta-analysis.
Sahebkar A · Phytotherapy research : PTR · 2014
Meta-analysis342 participants6 studies pooledflagAnti-Inflammatory Support forscienceCurcumin
- Effects of omega-3 supplementation on glucose and lipid metabolism in patients with gestational diabetes: A meta-analysis of randomized controlled trials.
Liu W; Gao M; Yang S; Sun C; Bi Y; Li Y; Wang J; Yuan X · Journal of diabetes and its complications · 2023
Meta-analysis331 participants6 studies pooledflagMetabolism Boost forscienceOmega-3
- The Role of Astaxanthin as an Antioxidant and Anti-Inflammatory Agent in Human Health: A Systematic Review.
Malcangi G; Inchingolo AM; Casamassima L; Trilli I; Ferrante L; Longo M; Inchingolo F; Marinelli G; Palermo A; Dipalma G; Inchingolo AD · International journal of molecular sciences · 2026
Systematic review15 studies pooledflagAnti-Inflammatory Support forscienceAstaxanthin
- The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects: A phase 2 randomized, placebo-controlled trial with a multi-arm, parallel-group design.
Karandish M; Mozaffari-Khosravi H; Mohammadi SM; Cheraghian B; Azhdari M · Phytotherapy research : PTR · 2021
Randomized trial84 participantsflagMetabolism Boost forscienceCurcumin
- Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials.
Wang W; Xu Y; Zhou J; Zang Y · Clinical rheumatology · 2024
Meta-analysis1,018 participants18 studies pooledflagJoint Health forscienceOmega-3
- Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
Randomized trial77 participantsflagAnti-Inflammatory Support forscienceFish Oil
- Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis.
Wan S; Wu W; Zhang Y; He J; Wang X; An P; Luo J; Zhu Y; Luo Y · Nutrients · 2024
Meta-analysisflagCardiovascular Support forscienceAstaxanthin
- Efficacy and safety of curcumin therapy for knee osteoarthritis: A Bayesian network meta-analysis.
Zhao J; Liang G; Zhou G; Hong K; Yang W; Liu J; Zeng L · Journal of ethnopharmacology · 2024
Meta-analysis2,175 participants23 studies pooledflagJoint Health forscienceCurcumin
- Micronutrient Supplementation to Reduce Cardiovascular Risk.
An P; Wan S; Luo Y; Luo J; Zhang X; Zhou S; Xu T; He J; Mechanick JI; Wu WC; Ren F; Liu S · Journal of the American College of Cardiology · 2022
Meta-analysis883,627 participants884 studies pooledflagCardiovascular Support forscienceCurcumin
- A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee.
Sengupta K; Alluri KV; Satish AR; Mishra S; Golakoti T; Sarma KV; Dey D; Raychaudhuri SP · Arthritis research & therapy · 2009
Randomized trial75 participantsflagJoint Health flagAnti-Inflammatory Support forscienceBoswellia
- Effect of curcumin on inflammatory markers and disease activity in patients with rheumatoid arthritis: A meta-analysis.
Zhang F; Niu B · Medicine · 2025
Meta-analysis7 studies pooledflagAnti-Inflammatory Support forscienceCurcumin
- Efficacy and safety of Rhizoma curcumea longae with respect to improving the glucose metabolism of patients at risk for cardiovascular disease: a meta-analysis of randomised controlled trials.
Huang J; Qin S; Huang L; Tang Y; Ren H; Hu H · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2020
Meta-analysis1,277 participants14 studies pooledflagMetabolism Boost forscienceCurcumin
- Astaxanthin ameliorates inflammation, oxidative stress, and reproductive outcomes in endometriosis patients undergoing assisted reproduction: A randomized, triple-blind placebo-controlled clinical trial.
Rostami S; Alyasin A; Saedi M; Nekoonam S; Khodarahmian M; Moeini A; Amidi F · Frontiers in endocrinology · 2023
Randomized trial50 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- Boswellic Acids Improve Clinical Cognitive Scores and Reduce Systemic Inflammation in Patients with Mild to Moderate Alzheimer's Disease.
Karima S; Aghamollaii V; Mahmoodi Baram S; Balenci L; Lanctôt KL; Kiss A; Tafakhori A; Mahdavi M; Rajaei S; Shateri S; Yarhoseini A; Mokhtari F; Fotouhi A; Riazi A · Journal of Alzheimer's disease : JAD · 2023
Randomized trial85 participantsflagAnti-Inflammatory Support forscienceBoswellia
- Supplementation of fish oil and olive oil in patients with rheumatoid arthritis.
Berbert AA; Kondo CR; Almendra CL; Matsuo T; Dichi I · Nutrition (Burbank, Los Angeles County, Calif.) · 2005
Randomized trial43 participantsflagJoint Health forscienceOmega-3
- Fish oil supplementation and insulin sensitivity: a systematic review and meta-analysis.
Gao H; Geng T; Huang T; Zhao Q · Lipids in health and disease · 2018
Meta-analysis672 participants17 studies pooledflagMetabolism Boost forscienceOmega-3
- Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
Randomized trial60 participantsflagAnti-Inflammatory Support forscienceFish Oil
- Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia.
Yoshida H; Yanai H; Ito K; Tomono Y; Koikeda T; Tsukahara H; Tada N · Atherosclerosis · 2010
Randomized trial61 participantsflagCardiovascular Support forscienceAstaxanthin
- Efficacy and Safety of Curcumin and Curcuma longa Extract in the Treatment of Arthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trial.
Zeng L; Yang T; Yang K; Yu G; Li J; Xiang W; Chen H · Frontiers in immunology · 2022
Meta-analysis2,396 participants29 studies pooledflagJoint Health forscienceCurcumin
- Efficacy and Safety of Aflapin®, a Novel Boswellia Serrata Extract, in the Treatment of Osteoarthritis of the Knee: A Short-Term 30-Day Randomized, Double-Blind, Placebo-Controlled Clinical Study.
Karlapudi V; Sunkara KB; Konda PR; Sarma KV; Rokkam MP · Journal of the American Nutrition Association · 2023
Randomized trial70 participantsflagJoint Health forscienceBoswellia
- Effect of curcumin on C-reactive protein as a biomarker of systemic inflammation: An updated meta-analysis of randomized controlled trials.
Gorabi AM; Abbasifard M; Imani D; Aslani S; Razi B; Alizadeh S; Bagheri-Hosseinabadi Z; Sathyapalan T; Sahebkar A · Phytotherapy research : PTR · 2022
Meta-analysis32 studies pooledflagAnti-Inflammatory Support forscienceCurcumin
- The Effect of Curcumin Supplementation on Pulse Wave Velocity in Patients with Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Alidadi M; Sahebkar A; Eslami S; Vakilian F; Jarahi L; Alinezhad-Namaghi M; Arabi SM; Vakili S; Tohidinezhad F; Nikooiyan Y; Norouzy A · Advances in experimental medicine and biology · 2021
Randomized trial66 participantsflagCardiovascular Support forscienceCurcumin
- The effects of curcumin intake on wound healing and metabolic status in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
Mokhtari M; Razzaghi R; Momen-Heravi M · Phytotherapy research : PTR · 2021
Randomized trial60 participantsflagMetabolism Boost forscienceCurcumin
- Efficacy of fish oil and its components in the management of psoriasis: a systematic review of 18 randomized controlled trials.
Chen X; Hong S; Sun X; Xu W; Li H; Ma T; Zheng Q; Zhao H; Zhou Y; Qiang Y; Li B; Li X · Nutrition reviews · 2021
Meta-analysis927 participants18 studies pooledflagAnti-Inflammatory Support forscienceFish Oil
- Improvement in Glycolipid Metabolism Parameters After Supplementing Fish Oil-Derived Omega-3 Fatty Acids Is Associated with Gut Microbiota and Lipid Metabolites in Type 2 Diabetes Mellitus.
Xia J; Yin S; Yu J; Wang J; Jin X; Wang Y; Liu H; Sun G · Nutrients · 2024
Randomized trial110 participantsflagMetabolism Boost forscienceOmega-3
- Impact of type and dose of oral polyunsaturated fatty acid supplementation on disease activity in inflammatory rheumatic diseases: a systematic literature review and meta-analysis.
Sigaux J; Mathieu S; Nguyen Y; Sanchez P; Letarouilly JG; Soubrier M; Czernichow S; Flipo RM; Sellam J; Daïen C · Arthritis research & therapy · 2022
Meta-analysis1,420 participants30 studies pooledflagJoint Health forscienceOmega-3
- Redox-sensitive miRNAs and Humanin could mediate effects of exercise and astaxanthin on oxidative stress and inflammation in type 2 diabetes.
Basereh A; Khoramipour K; Hosseini N; HajHosseini M; Khodabakhshi A; Amirkhosravi L; Khoramipour K · Scientific reports · 2025
Randomized trial90 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- Effects of Astaxanthin Supplementation on Glycemic Control and Lipid Profile in Patients With Prediabetes and Type 2 Diabetes: A Meta-Analysis of Randomized Controlled Trials.
Molani-Gol R; Bohlouli Sardroudi S; Rafraf M · Nutrition and metabolic insights · 2026
Meta-analysis403 participants9 studies pooledflagCardiovascular Support forscienceAstaxanthin
- Efficacy and Safety of a Novel Low-Dose Water-Dispersible Turmeric Extract in the Management of Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Thanawala S; Shah R; Alluri KV; Bhupathiraju K; Prasad N; Agarwal Y · Journal of pain research · 2025
Randomized trial139 participantsflagJoint Health forscienceCurcumin
- Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis.
Zhang Y; Gui Y; Adams R; Farragher J; Itsiopoulos C; Bow K; Cai M; Han J · Nutrients · 2025
Meta-analysis4,599 participants39 studies pooledflagJoint Health forscienceBoswellia
- Effects of curcumin on blood pressure: A systematic review and dose-response meta-analysis.
Karimi A; Moini Jazani A; Darzi M; Doost Azgomi RN; Vajdi M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2026
Meta-analysis1,377 participants17 studies pooledflagCardiovascular Support forscienceCurcumin
- Effects of metformin and curcumin in women with polycystic ovary syndrome: A factorial clinical trial.
Feghhi F; Ghaznavi H; Sheervalilou R; Razavi M; Sepidarkish M · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2024
Randomized trial200 participantsflagMetabolism Boost forscienceCurcumin
- The effects of fish oil supplementation on markers of inflammation in chronic kidney disease patients.
Deike E; Bowden RG; Moreillon JJ; Griggs JO; Wilson RL; Cooke M; Shelmadine BD; Beaujean AA · Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2013
Randomized trial31 participantsflagAnti-Inflammatory Support forscienceFish Oil
- Fish oil in knee osteoarthritis: a randomised clinical trial of low dose versus high dose.
Hill CL; March LM; Aitken D; Lester SE; Battersby R; Hynes K; Fedorova T; Proudman SM; James M; Cleland LG; Jones G · Annals of the rheumatic diseases · 2016
Randomized trial202 participantsflagJoint Health forscienceOmega-3
- Oils Rich in α-Linolenic Acid or Docosahexaenoic Acid Have Distinct Effects on Plasma Oxylipin and Adiponectin Concentrations and on Monocyte Bioenergetics in Women with Obesity.
Pauls SD; Rodway LR; Sidhu KK; Winter T; Sidhu N; Aukema HM; Zahradka P; Taylor CG · The Journal of nutrition · 2022
Randomized trialflagMetabolism Boost forscienceOmega-3
- Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity.
Saeidi A; Nouri-Habashi A; Razi O; Ataeinosrat A; Rahmani H; Mollabashi SS; Bagherzadeh-Rahmani B; Aghdam SM; Khalajzadeh L; Al Kiyumi MH; Hackney AC; Laher I; Heinrich KM; Zouhal H · Nutrients · 2023
Randomized trial68 participantsflagCardiovascular Support forscienceAstaxanthin
- Bio-optimized Curcuma longa extract is efficient on knee osteoarthritis pain: a double-blind multicenter randomized placebo controlled three-arm study.
Henrotin Y; Malaise M; Wittoek R; de Vlam K; Brasseur JP; Luyten FP; Jiangang Q; Van den Berghe M; Uhoda R; Bentin J; De Vroey T; Erpicum L; Donneau AF; Dierckxsens Y · Arthritis research & therapy · 2020
Randomized trial150 participantsflagJoint Health forscienceCurcumin
- Effect of curcumin on circulating interleukin-6 concentrations: A systematic review and meta-analysis of randomized controlled trials.
Derosa G; Maffioli P; Simental-Mendía LE; Bo S; Sahebkar A · Pharmacological research · 2018
Meta-analysis9 studies pooledflagAnti-Inflammatory Support forscienceCurcumin
- Effects of nanocurcumin supplementation on metabolic syndrome: A systematic review and meta-analysis of randomized controlled trials.
Wilar G; Suhandi C; Fukunaga K; Shigeno M; Kawahata I; Abdulah R; Sasaki T · Pharmacological research · 2025
Meta-analysis1,394 participants20 studies pooledflagCardiovascular Support forscienceCurcumin
- The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
Randomized trial174 participantsflagAnti-Inflammatory Support forscienceFish Oil
- Effect of Curcumin on Glycaemic and Lipid Parameters in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Simental-Mendía LE; Shah N; Sathyapalan T; Majeed M; Orekhov AN; Jamialahmadi T; Sahebkar A · Reproductive sciences (Thousand Oaks, Calif.) · 2022
Meta-analysis5 studies pooledflagMetabolism Boost forscienceCurcumin
- Dietary Long-Chain n-3 Fatty Acid Intake and Arthritis Risk in the Women's Health Initiative.
Krok-Schoen JL; Brasky TM; Hunt RP; Rohan TE; Baker TA; Li W; Carbone L; Mackey RH; Snetselaar L; Lustberg MB; Neuhouser ML · Journal of the Academy of Nutrition and Dietetics · 2019
Cohort study80,551 participantsflagJoint Health forscienceOmega-3
- Astaxanthin supplementation counters exercise-induced decreases in immune-related plasma proteins.
Nieman DC; Woo J; Sakaguchi CA; Omar AM; Tang Y; Davis K; Pecorelli A; Valacchi G; Zhang Q · Frontiers in nutrition · 2023
Randomized trialflagAnti-Inflammatory Support forscienceAstaxanthin
- The consumption of omega-3 polyunsaturated fatty acids improves clinical outcomes and prognosis in pancreatic cancer patients: a systematic evaluation.
Ma YJ; Yu J; Xiao J; Cao BW · Nutrition and cancer · 2015
Meta-analysis11 studies pooledflagMetabolism Boost forscienceOmega-3
- The effect of astaxanthin supplementation on inflammatory markers, lipid profile, and anthropometric indices in patients with heart failure: a randomized controlled trial.
Ghotboddin Mohammadi S; Shafie D; Feizi A; Ahmadi AR; Bagherniya M; Kafeshani M · Scientific reports · 2026
Randomized trial80 participantsflagCardiovascular Support forscienceAstaxanthin
- Short-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective study.
Nakagawa Y; Mukai S; Yamada S; Matsuoka M; Tarumi E; Hashimoto T; Tamura C; Imaizumi A; Nishihira J; Nakamura T · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2015
Randomized trial50 participantsflagJoint Health forscienceCurcumin
- Efficacy of curcumin and Boswellia for knee osteoarthritis: Systematic review and meta-analysis.
Bannuru RR; Osani MC; Al-Eid F; Wang C · Seminars in arthritis and rheumatism · 2019
Meta-analysis1,009 participants11 studies pooledflagJoint Health forscienceBoswellia
- The effects of nanocurcumin supplementation on inflammation in hemodialysis patients: A randomized controlled trial.
Vafadar-Afshar G; Rasmi Y; Yaghmaei P; Khadem-Ansari MH; Makhdoomi K; Rasouli J · Hemodialysis international. International Symposium on Home Hemodialysis · 2021
Randomized trial54 participantsflagAnti-Inflammatory Support forscienceCurcumin
- The Effects of Curcumin on Glycemic Control and Lipid Profiles Among Patients with Metabolic Syndrome and Related Disorders: A Systematic Review and Metaanalysis of Randomized Controlled Trials.
Tabrizi R; Vakili S; Lankarani KB; Akbari M; Mirhosseini N; Ghayour-Mobarhan M; Ferns G; Karamali F; Karamali M; Taghizadeh M; Kouchaki E; Asemi Z · Current pharmaceutical design · 2019
Meta-analysis1,890 participants26 studies pooledflagCardiovascular Support forscienceCurcumin
- A full-spectrum Boswellia serrata extract with enhanced bioavailability, and its co-delivered system with curcumin alleviate pain and stiffness associated with moderate spondylitis: a randomized double-blind, placebo-controlled, 3-arm study.
Mamatha K; Prabhakaran P; Syam Das S; Kanjoormana Aryan M; Thomas J · Frontiers in pharmacology · 2025
Randomized trial105 participantsflagAnti-Inflammatory Support forscienceBoswellia
- A systematic review and meta-analysis of the n-3 polyunsaturated fatty acids effects on inflammatory markers in colorectal cancer.
Mocellin MC; Camargo CQ; Nunes EA; Fiates GMR; Trindade EBSM · Clinical nutrition (Edinburgh, Scotland) · 2017
Meta-analysis475 participants9 studies pooledflagAnti-Inflammatory Support forscienceFish Oil
- Astaxanthin treatment decreases pro-inflammatory cytokines and improves reproductive outcomes in patients with polycystic ovary syndrome undergoing assisted reproductive technology: A randomized clinical trial.
Fereidouni F; Kashani L; Amidi F; Khodarahmian M; Zhaeentan S; Ardehjani NA; Rastegar T · Inflammopharmacology · 2024
Randomized trial44 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- Effect of long-term omega-3 supplementation and a lifestyle multidomain intervention on intrinsic capacity among community-dwelling older adults: Secondary analysis of a randomized, placebo-controlled trial (MAPT study).
Giudici KV; de Souto Barreto P; Beard J; Cantet C; Araujo de Carvalho I; Rolland Y; Vellas B; MAPT DSA group · Maturitas · 2020
Randomized trial1,445 participantsflagJoint Health forscienceOmega-3
- Efficacy of Curcumin on Treating Cancer Anorexia-Cachexia Syndrome in Locally or Advanced Head and Neck Cancer: A Double-Blind, Placebo-Controlled Randomised Phase IIa Trial (CurChexia).
Thambamroong T; Seetalarom K; Saichaemchan S; Pumsutas Y; Prasongsook N · Journal of nutrition and metabolism · 2024
Randomized trial20 participantsflagMetabolism Boost forscienceCurcumin
- Effect of isotretinoin and omega-3 fatty acid combination on lipid metabolism in patients with acne vulgaris: a randomized controlled trial.
Du P; Huang Y; Hu J; Xiong X; Deng Y · Lipids in health and disease · 2026
Randomized trial66 participantsflagMetabolism Boost forscienceOmega-3
- Astaxanthin, oxidative stress, inflammation and cardiovascular disease.
Fassett RG; Coombes JS · Future cardiology · 2009
Narrative reviewflagCardiovascular Support forscienceAstaxanthin
- The efficacy of curcumin in relieving osteoarthritis: A meta-analysis of meta-analyses.
Bideshki MV; Jourabchi-Ghadim N; Radkhah N; Behzadi M; Asemani S; Jamilian P; Zarezadeh M · Phytotherapy research : PTR · 2024
Meta-analysis11 studies pooledflagJoint Health forscienceCurcumin
- The effects of curcumin supplementation on biomarkers of inflammation, oxidative stress, and endothelial function: A meta-analysis of meta-analyses.
Kavyani Z; Najafi K; Naghsh N; Karvane HB; Musazadeh V · Prostaglandins & other lipid mediators · 2024
Meta-analysis21 studies pooledflagAnti-Inflammatory Support forscienceCurcumin
- Comparative efficacy and tolerability of 5-Loxin and AflapinAgainst osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study.
Sengupta K; Krishnaraju AV; Vishal AA; Mishra A; Trimurtulu G; Sarma KV; Raychaudhuri SK; Raychaudhuri SP · International journal of medical sciences · 2011
Randomized trial60 participantsflagJoint Health forscienceBoswellia
- Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
Meta-analysis49 studies pooledflagAnti-Inflammatory Support forscienceFish Oil
- Beneficial effect of n-3 polyunsaturated fatty acids on inflammation and analgesic use in psoriatic arthritis: a randomized, double blind, placebo-controlled trial.
Kristensen S; Schmidt EB; Schlemmer A; Rasmussen C; Johansen MB; Christensen JH · Scandinavian journal of rheumatology · 2018
Randomized trial145 participantsflagJoint Health forscienceOmega-3
- The antioxidant and anti-inflammatory effects of astaxanthin supplementation on the expression of miR-146a and miR-126 in patients with type 2 diabetes mellitus: A randomised, double-blind, placebo-controlled clinical trial.
Shokri-Mashhadi N; Tahmasebi M; Mohammadi-Asl J; Zakerkish M; Mohammadshahi M · International journal of clinical practice · 2021
Randomized trial44 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- Impact of exercise intervention with or without curcumin supplementation on body fat composition, glucose, and lipid metabolism in obese adults: A meta-analysis.
Li Y; Guo L; Zhang D; Ma J · Lipids · 2025
Meta-analysis183 participants7 studies pooledflagMetabolism Boost forscienceCurcumin
- Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities.
Efferth T; Oesch F · Seminars in cancer biology · 2022
Systematic reviewflagAnti-Inflammatory Support forscienceBoswellia
- Supplementation with n-3 fatty acids reduces triglycerides but increases PAI-1 in non-insulin-dependent diabetes mellitus.
Boberg M; Pollare T; Siegbahn A; Vessby B · European journal of clinical investigation · 1993
Randomized trial14 participantsflagMetabolism Boost forscienceOmega-3
- The effect of astaxanthin supplementation on inflammatory markers, oxidative stress indices, lipid profile, uric acid level, blood pressure, endothelial function, quality of life, and disease symptoms in heart failure subjects.
Mohammadi SG; Feizi A; Bagherniya M; Shafie D; Ahmadi AR; Kafeshani M · Trials · 2024
Protocol80 participantsflagCardiovascular Support forscienceAstaxanthin
- Astaxanthin Modulates Inflammation in Type 2 Diabetes via Regulation of microRNAs, Lysophosphatidylcholine, and α-Hydroxybutyrate.
Sharifi-Rigi A; Zal F; Aarabi MH; Dehghani M; Roustaei Rad N; Taghiyar S · International journal of endocrinology · 2025
Randomized trial50 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- Is Curcumin Intake Really Effective for Chronic Inflammatory Metabolic Disease? A Review of Meta-Analyses of Randomized Controlled Trials.
Lee YM; Kim Y · Nutrients · 2024
Systematic review54 studies pooledflagAnti-Inflammatory Support forscienceCurcumin
- Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
Randomized trial201 participantsflagAnti-Inflammatory Support forscienceFish Oil
- Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
Meta-analysis127,477 participants13 studies pooledflagCardiovascular Support forscienceFish Oil
- Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
Randomized trial309 participantsflagCardiovascular Support forscienceFish Oil
- A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
Meta-analysis1,524 participants17 studies pooledflagCardiovascular Support forscienceFish Oil
- Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
Randomized trial422 participantsflagCardiovascular Support forscienceFish Oil
- Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
Meta-analysis6 studies pooledflagCardiovascular Support forscienceFish Oil
- A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of a Krill Oil, Astaxanthin, and Oral Hyaluronic Acid Complex on Joint Health in People with Mild Osteoarthritis.
Hill WS; Dohnalek MH; Ha Y; Kim SJ; Jung JC; Kang SB · Nutrients · 2023
Randomized trial100 participantsflagJoint Health forscienceAstaxanthin
- Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study.
Haroyan A; Mukuchyan V; Mkrtchyan N; Minasyan N; Gasparyan S; Sargsyan A; Narimanyan M; Hovhannisyan A · BMC complementary and alternative medicine · 2018
Randomized trial201 participantsflagJoint Health forscienceBoswellia
- The efficacy of high- and low-dose curcumin in knee osteoarthritis: A systematic review and meta-analysis.
Hsiao AF; Lien YC; Tzeng IS; Liu CT; Chou SH; Horng YS · Complementary therapies in medicine · 2021
Meta-analysis1,258 participants11 studies pooledflagJoint Health forscienceCurcumin
- A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain.
Goldberg RJ; Katz J · Pain · 2007
Meta-analysis17 studies pooledflagJoint Health forscienceOmega-3
- Effects of curcumin on body weight, glycemic control and serum lipids in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial.
Jamilian M; Foroozanfard F; Kavossian E; Aghadavod E; Shafabakhsh R; Hoseini A; Asemi Z · Clinical nutrition ESPEN · 2021
Randomized trial60 participantsflagMetabolism Boost forscienceCurcumin
- Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism.
Green CJ; Pramfalk C; Charlton CA; Gunn PJ; Cornfield T; Pavlides M; Karpe F; Hodson L · BMJ open diabetes research & care · 2021
Randomized trial38 participantsflagMetabolism Boost forscienceOmega-3
- Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
Randomized trial60 participantsflagMetabolism Boost flagSkin Health forscienceOmega-3
- The Effects of Flaxseed Oil Omega-3 Fatty Acids Supplementation on Metabolic Status of Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Mirmasoumi G; Fazilati M; Foroozanfard F; Vahedpoor Z; Mahmoodi S; Taghizadeh M; Esfeh NK; Mohseni M; Karbassizadeh H; Asemi Z · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2018
Randomized trial60 participantsflagMetabolism Boost forscienceOmega-3
- A combination of omega-3 and plant sterols regulate glucose and lipid metabolism in individuals with impaired glucose regulation: a randomized and controlled clinical trial.
Wang JF; Zhang HM; Li YY; Xia S; Wei Y; Yang L; Wang D; Ye JJ; Li HX; Yuan J; Pan RR · Lipids in health and disease · 2019
Randomized trial200 participantsflagMetabolism Boost forscienceOmega-3
- The Protective Role of Astaxanthin for UV-Induced Skin Deterioration in Healthy People-A Randomized, Double-Blind, Placebo-Controlled Trial.
Ito N; Seki S; Ueda F · Nutrients · 2018
Randomized trial23 participantsflagSkin Health forscienceAstaxanthin
- Supplementating with dietary astaxanthin combined with collagen hydrolysate improves facial elasticity and decreases matrix metalloproteinase-1 and -12 expression: a comparative study with placebo.
Yoon HS; Cho HH; Cho S; Lee SR; Shin MH; Chung JH · Journal of medicinal food · 2015
Randomized trial44 participantsflagSkin Health forscienceAstaxanthin
- Continuous astaxanthin intake reduces oxidative stress and reverses age-related morphological changes of residual skin surface components in middle-aged volunteers.
Chalyk NE; Klochkov VA; Bandaletova TY; Kyle NH; Petyaev IM · Nutrition research (New York, N.Y.) · 2018
Single-arm trial31 participantsflagSkin Health forscienceAstaxanthin
- The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity.
Phetcharat L; Wongsuphasawat K; Winther K · Clinical interventions in aging · 2016
Randomized trial34 participantsflagSkin Health forscienceAstaxanthin
- Cosmetic benefits of astaxanthin on humans subjects.
Tominaga K; Hongo N; Karato M; Yamashita E · Acta biochimica Polonica · 2012
Other66 participantsflagSkin Health forscienceAstaxanthin
- Dietetic intervention in psoriatic arthritis: the DIETA trial.
Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
Randomized trial97 participantsflagSkin Health forscienceOmega-3
- Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
Randomized trial49 participantsflagSkin Health forscienceOmega-3
- Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
Randomized trial50 participantsflagSkin Health forscienceOmega-3
- Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
Randomized trial42 participantsflagSkin Health forscienceOmega-3