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Extra Care Liver Support

Renew Life
4.8
★ ★ ★ ★ ★
(337 ratings)
Selenium 175 mcg
Green Tea 30 mg
Milk Thistle 600 mg
Product Image
Score68
Broad liver-oriented coverage with a solid core, but several supporting ingredients are too modest to justify the formula on their own.
How scoring works
Quantity:90 Capsule(s) • (30 servings)
Goals:
Detoxification
General Health
Immunity

Score 68

Broad liver-oriented coverage with a solid core, but several supporting ingredients are too modest to justify the formula on their own.
How scoring works
$29.99($0.99 per serving)
Vitacost
$ 36.79
Pure Formulas
$ 29.99
iHerb
$ 30.59
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Analysis

Milk thistle, vitamin C, selenium, alpha-lipoic acid, and amino acids form a broad liver-support and antioxidant base. The 600 mg milk thistle entry is substantial, though the supplied form information does not clarify the exact extract concentration.

Quercetin, artichoke, green tea, phosphatidylcholine, and glutathione add pathway variety. Most of these sit at modest amounts, with 10 mg glutathione and 30 mg green tea unlikely to drive the result.

Ingredient quantities are individually disclosed, which makes the crowded formula reasonably easy to assess. The higher serving cost and several token-dose additions reduce the practical value for someone who mainly wants milk thistle or antioxidant support.

Who is it for
  • Adults seeking a multi-pathway liver-support formula
  • People who want milk thistle plus antioxidant nutrients
Best for
  • Broad antioxidant coverage
  • Combining milk thistle with selenium and vitamin C

Pros

  • Substantial milk thistle entry
  • 175 mcg selenomethionine
  • Multiple complementary antioxidant ingredients
  • Individually disclosed amounts

Cons

  • Glutathione is only 10 mg
  • Green tea and phosphatidylcholine are modest
  • Milk thistle concentration is unclear
  • Serving value is limited

Warnings

  • The 175 mcg selenium amount can add up quickly when combined with a multivitamin or other selenium supplement.
  • Alpha-lipoic acid may add to glucose-lowering effects in people using insulin or other diabetes medicines.

Nutrient quality

77 High impact

The main antioxidant and liver-focused ingredients align well with the intended use. Incomplete botanical standardization and several small additions weaken dose confidence.

.

Ingredient transparency

73 High impact

Individual active weights are disclosed without a hidden blend. Extract potency, caffeine status, full directions, and inactive ingredients are not supplied.

.

Customer satisfaction

67 High impact

The average customer rating is very strong. The rating base is adequate but not especially deep, while specific review experiences were not supplied.

.

Value for money

53 Moderate impact

Serving economics are weak. Formula weaknesses do not justify the asking price well.

.
Report analysis

Goals

Detoxification
Detoxification
Impact
Highest effect
A Goal FitB- Strength of SupportB+ CoverageB Formula Quality
Selenium · 175 mcgMilk Thistle · 600 mgVitamin C · 300 mg

Milk thistle, selenium, vitamin C, and alpha-lipoic acid form a strong liver-protection and antioxidant core. Amino acids and phosphatidylcholine add possible conjugation and membrane support, although their composition or amounts are limited.

The 600 mg milk thistle extract is substantial, but the label does not state a separate active silymarin yield. Glutathione, artichoke, green tea, and phosphatidylcholine appear at small supporting amounts rather than full standalone doses.

Study evidence
Green Tea Disputed 16 studies
Milk Thistle Supportive 46 studies
Selenium Supportive 10 studies
Vitamin C Supportive 9 studies
General Health
General Health
Impact
High effect
B- Goal FitB- Strength of SupportC+ CoverageC+ Formula Quality
Selenium · 175 mcgVitamin C · 300 mg

Selenium, vitamin C, milk thistle, and alpha lipoic acid create a plausible antioxidant and liver-focused combination. Selenium uses a well-absorbed form, while vitamin C and milk thistle are present at meaningful amounts.

Several smaller actives and an undisclosed amino acid blend make the broad formula uneven. Its liver emphasis offers some general antioxidant support but is narrower than a comprehensive daily-health formula.

Study evidence
Selenium Supportive 70 studies
Vitamin C Supportive 56 studies
Immunity
Immunity
Impact
High effect
C+ Goal FitB- Strength of SupportC+ CoverageC+ Formula Quality
Vitamin C · 300 mgSelenium · 175 mcg

Vitamin C, selenium, milk thistle, alpha lipoic acid, and other actives provide broad antioxidant and liver-focused support. L-selenomethionine and a substantial milk thistle amount are the clearest formulation strengths.

The product is more specialized than a general daily foundation, and the amino acid blend hides its individual amounts. Green tea marker content and caffeine are not disclosed, while selenium intake should be considered alongside other supplements.

Study evidence
Green Tea Not classified 2 studies
Selenium Mixed 37 studies
Vitamin C Supportive 53 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
 300 mg
Selenium (L-Selenomethionine)
 175 mcg
Milk Thistle extract (Silymarin)
 600 mg
Amino Acid Complex
600 mg
Alpha Lipoic Acid
100 mg
Quercetin
75 mg
Artichoke extract
30 mg
Green Tea extract
30 mg
Phosphatidylcholine
30 mg
L-Glutathione
10 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Selenium (L-Selenomethionine) · 175 mcg OverallScore77
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

L-selenomethionine provides a well-absorbed organic form with precise isomer disclosure. The maintenance-level amount remains comfortably below the upper limit while approaching the common clinical target. Selenium-specific value is weak, though the multi-ingredient formula may matter to shoppers seeking its broader blend.

View ingredientView products
Green Tea · 30 mg OverallScore12
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

Green tea is a small component of a broader liver-support formula, while vitamin C may help stabilize catechins. The label does not state EGCG yield, active-marker percentage, or caffeine content. Active-dose suitability and green-tea-specific value therefore cannot be verified.

View ingredientView products
Milk Thistle (Silymarin) · 600 mg OverallScore5
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

A large milk thistle extract entry appears substantial, but the active silymarin amount is not disclosed. The dry capsules do not use a defined phytosome, and the source plant part remains unclear. The high serving cost lacks enough milk-thistle-specific quality evidence to support it.

View ingredientView products
Loading alternative details
67 Performance

Puri-T

LifeSeasons
<p>Milk thistle, N-acetyl cysteine, selenium, and related botanicals provide a coherent liver-support base. A more coherent liver or antioxidant profile strengthens the comparison with the original, though missing active-marker yields still limit potency certainty.</p>
73 Performance

Detox & Liver Health

Reg'Activ
<p>Selenomethionine, milk thistle, and a probiotic strain create a plausible liver and antioxidant formula, but milk thistle is not standardized and the N-acetyl cysteine and methionine amounts are modest. A more coherent liver or antioxidant profile strengthens the comparison with the original, though missing active-marker yields still limit potency certainty.</p>
82 Performance

EstroSense

Natural Factors WS WomenSense
<p>A hormone-metabolism blend combines DIM, indole compounds, green tea, turmeric, and milk thistle. A more coherent liver or antioxidant profile strengthens the comparison with the original, though missing active-marker yields still limit potency certainty.</p>
74 Budget

Glutathione Booster

Carlson
<p>The antioxidant formula combines vitamin C, selenium, N-acetyl cysteine, milk thistle, garlic, and alpha lipoic acid, but several important actives are modest or unstandardized. The lower serving cost improves accessibility compared with the original, but narrower liver coverage or lightly dosed supporting ingredients limit interchangeability.</p>
77 Budget

Kyolic AC E & Herbal Antioxidants

Kyolic
<p>Aged garlic, natural vitamin E, selenium, and several plant antioxidants create a coherent general antioxidant formula. The lower serving cost improves accessibility compared with the original, but narrower liver coverage or lightly dosed supporting ingredients limit interchangeability.</p>
66 Budget

Complete Liver Cleanse

Nature's Way
<p>Standardized milk thistle leads a broad liver-support formula with glutathione, selenium, calcium D-glucarate, turmeric, dandelion, and artichoke. The lower serving cost improves accessibility compared with the original, but narrower liver coverage or lightly dosed supporting ingredients limit interchangeability.</p>
73 Value

Glutathione Booster

Carlson
<p>The antioxidant formula combines vitamin C, selenium, N-acetyl cysteine, milk thistle, garlic, and alpha lipoic acid, but several important actives are modest or unstandardized. Relevant liver-support or antioxidant ingredients at a lower serving cost improve value, while incomplete standardization keeps the comparison qualified.</p>
81 Value

EstroSense

Natural Factors WS WomenSense
<p>A hormone-metabolism blend combines DIM, indole compounds, green tea, turmeric, and milk thistle. Relevant liver-support or antioxidant ingredients at a lower serving cost improve value, while incomplete standardization keeps the comparison qualified.</p>
78 Value

Ocu Support

NOW
<p>Lutein, zeaxanthin, bilberry, zinc, selenium, green tea, and N-acetyl cysteine create a well-targeted eye-support formula. Relevant liver-support or antioxidant ingredients at a lower serving cost improve value, while incomplete standardization keeps the comparison qualified.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Selenium-Biofortified Strawberries Improve Glucose Homeostasis and Hepatic Function: A 30-Day Randomized Controlled Trial in Healthy Adults.
    Vasto S; Di Rosa L; Ferrantelli V; Fiore AS; Giordano CP; Cannizzaro A; Sabatino L; Macaluso A; Caldarella R; Caldara GF; Baldassano S · Nutrients · 2026
    Randomized trial35 participantsDetoxification forSelenium
  2. Meta-analysis: antioxidant supplements for liver diseases - the Cochrane Hepato-Biliary Group.
    Bjelakovic G; Gluud LL; Nikolova D; Bjelakovic M; Nagorni A; Gluud C · Alimentary pharmacology & therapeutics · 2011
    Meta-analysis1,225 participants20 studies pooledDetoxification forSelenium
  3. Exposure to a high selenium environment in Punjab, India: Effects on blood chemistry.
    Loomba R; Filippini T; Chawla R; Chaudhary R; Cilloni S; Datt C; Singh S; Dhillon KS; Vinceti M · The Science of the total environment · 2020
    Cross-sectional study680 participantsDetoxification forSelenium
  4. Supplementation with selenium can influence nausea, fatigue, physical, renal, and liver function of children and adolescents with cancer.
    Vieira ML; Fonseca FL; Costa LG; Beltrame RL; Chaves CM; Cartum J; Alves SI; Azzalis LA; Junqueira VB; Pereria EC; Rocha KC · Journal of medicinal food · 2015
    Randomized trialDetoxification forSelenium
  5. A short-term intervention trial with selenate, selenium-enriched yeast and selenium-enriched milk: effects on oxidative defence regulation.
    Ravn-Haren G; Bügel S; Krath BN; Hoac T; Stagsted J; Jørgensen K; Bresson JR; Larsen EH; Dragsted LO · The British journal of nutrition · 2008
    Randomized trialDetoxification forSelenium
  6. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  7. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  8. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  9. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  10. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  11. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  12. Therapeutic benefits of green tea extract on various parameters in non-alcoholic fatty liver disease patients.
    Hussain M; Habib-Ur-Rehman; Akhtar L · Pakistan journal of medical sciences · 2024
    Randomized trial80 participantsDetoxification forGreen Tea
  13. The Effect of Green Tea Extract Supplementation on Liver Enzymes in Patients with Nonalcoholic Fatty Liver Disease.
    Pezeshki A; Safi S; Feizi A; Askari G; Karami F · International journal of preventive medicine · 2016
    Randomized trial80 participantsDetoxification forGreen Tea
  14. Green tea with high-density catechins improves liver function and fat infiltration in non-alcoholic fatty liver disease (NAFLD) patients: a double-blind placebo-controlled study.
    Sakata R; Nakamura T; Torimura T; Ueno T; Sata M · International journal of molecular medicine · 2014
    Randomized trial17 participantsDetoxification forGreen Tea
  15. Green tea consumption is associated with decreased DNA damage among GSTM1-positive smokers regardless of their hOGG1 genotype.
    Hakim IA; Chow HH; Harris RB · The Journal of nutrition · 2008
    Randomized trialDetoxification forGreen Tea
  16. Modulation of human glutathione s-transferases by polyphenon e intervention.
    Chow HH; Hakim IA; Vining DR; Crowell JA; Tome ME; Ranger-Moore J; Cordova CA; Mikhael DM; Briehl MM; Alberts DS · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2007
    Single-arm trial42 participantsDetoxification forGreen Tea
  17. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  18. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  19. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle
  20. [Selenium and oxidative stress in cancer patients].
    Gorozhanskaia ÉG; Sviridova SP; Dobrovol'skaia MM; Zybrikhina GN; Kashnia ShR · Biomeditsinskaia khimiia · 2014
    Single-arm trial40 participantsDetoxification forSelenium
  21. Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study.
    Li C; Peng X; Zheng J; Shi K; Qin L; Yang Q; Wang Z; Liu Y; Huang L · Biological trace element research · 2024
    Other40 participantsDetoxification forSelenium
  22. Heavy metals and metalloids exposure and liver function in Chinese adults - A nationally representative cross-sectional study.
    Wang S; Lyu Y; Ji S; Liu N; Wu B; Zhao F; Li Z; Qu Y; Zhu Y; Xie L; Li Y; Zhang Z; Song H; Hu X; Qiu Y; Zheng X; Zhang W; Yang Y; Li F; Cai J; Zhu Y; Cao Z; Tan F; Shi X · Environmental research · 2024
    Cross-sectional study9,445 participantsDetoxification forSelenium
  23. Vitamin C supplementation ameliorates liver function profile and antiviral treatment response in Hepatitis C patients.
    Nayila I; Javed MS; Khan MA; Hussain G; Raza Naqvi SA; Ali S; Jabeen Z; Shahnawaz S; Akram R; Iman T; Hassan Dogar MZ; Malik SA · Pakistan journal of pharmaceutical sciences · 2022
    Non-randomized trial200 participantsDetoxification forVitamin C
  24. Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress.
    Alleva R; Di Donato F; Strafella E; Staffolani S; Nocchi L; Borghi B; Pignotti E; Santarelli L; Tomasetti M · The British journal of nutrition · 2012
    Non-randomized trial46 participantsDetoxification forVitamin C
  25. Dietary Vitamin C Intake Is Associated With Improved Liver Function and Glucose Metabolism in Chinese Adults.
    Luo X; Zhang W; He Z; Yang H; Gao J; Wu P; Ma ZF · Frontiers in nutrition · 2022
    Observational study8,307 participantsDetoxification forVitamin C
  26. Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection.
    Trepanier LA; Yoder AR; Bajad S; Beckwith MD; Bellehumeur JL; Graziano FM · Journal of acquired immune deficiency syndromes (1999) · 2005
    Observational studyDetoxification forVitamin C
  27. Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso.
    Lavergne SN; Kurian JR; Bajad SU; Maki JE; Yoder AR; Guzinski MV; Graziano FM; Trepanier LA · Toxicology · 2006
    Clinical trial53 participantsDetoxification forVitamin C
  28. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  29. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  30. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  31. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  32. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  33. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  34. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  35. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  36. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  37. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  38. Preventive effects of tea and tea catechins against influenza and acute upper respiratory tract infections: a systematic review and meta-analysis
    Mai Umeda, Takeichiro Tominaga, Kazuya Kozuma, Hidefumi Kitazawa, Daisuke Furushima, Masanobu Hibi, Hiroshi Yamada · European Journal of Nutrition · 2021
    Meta-analysis3,748 participants10 studies pooledImmunity forGreen Tea
  39. Prevention of Acute Upper Respiratory Infections by Consumption of Catechins in Healthcare Workers: A Randomized, Placebo-Controlled Trial
    Daisuke Furushima, Takuma Nishimura, Norikata Takuma, Ryo Iketani, Tomohito Mizuno, Yuji Matsui, Tohru Yamaguchi, Yu Nakashima, Shinji Yamamoto, Masanobu Hibi, Hiroshi Yamada · Nutrients · 2019
    Randomized trial255 participantsImmunity forGreen Tea
  40. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  41. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  42. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  43. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  44. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  45. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  46. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  47. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  48. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  49. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C