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Melatonin 5 mg

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(14415 ratings)
Melatonin 5 mg
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Score81
The 5 mg capsule provides higher sleep-onset support, with next-morning effects as the main trade-off.
How scoring works
Quantity:180 Capsule(s) • (180 servings)
Goals:
Sleep Support
General Health
Brain Health

Score 81

The 5 mg capsule provides higher sleep-onset support, with next-morning effects as the main trade-off.
How scoring works
$11.60($0.06 per serving)
Walmart
$ 14.99
iHerb
$ 12.23
Vitacost
$ 13.13
Daily Vita
$ 11.60
Amazon
$ 11.60
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Analysis

Melatonin is supplied at 5 mg in one capsule. The amount is higher than many users need and raises the chance of morning effects. The clearly listed amount makes dose comparison simple.

The main benefit is support for circadian timing and falling asleep when a delayed schedule is the problem. The immediate-release format is aimed at sleep onset rather than all-night maintenance. It does not add a separate pathway for physical tension or daytime stress resilience.

A 180-serving bottle offers an unusually long and economical routine. The single-active formula keeps the purpose and serving easy to assess. Melatonin can still cause morning drowsiness or vivid dreams, especially when taken too late.

Who is it for
  • Adults who already know they tolerate higher-dose melatonin
  • People who prefer a simple capsule
Best for
  • Sleep-onset support
  • Circadian-timing routines

Pros

  • 5 mg melatonin amount is clearly listed
  • One-unit serving is simple
  • 180 servings per container
  • Focused single-active formula

Cons

  • No sustained-release feature for nighttime awakenings
  • Dose may be more than sensitive users need
  • No separate relaxation pathway

Warnings

  • The 5 mg melatonin serving may cause noticeable drowsiness, vivid dreams, headache, or dizziness.
  • Do not drive or perform safety-sensitive work after taking melatonin or the next morning if alertness is impaired.
  • Alcohol, sleep medicines, and other sedatives can add to melatonin-related drowsiness.

Nutrient quality

75 High impact

The capsule provides straightforward immediate-release delivery. The high 5 mg melatonin amount is higher than needed for many people despite supporting routine sleep-onset use.

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Ingredient transparency

84 Highest impact

Every supplied active ingredient has a specific amount and understandable name. Serving count is available, but intake directions and inactive ingredients are absent from the supplied label details.

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Customer satisfaction

70 High impact

The supplied aggregate rating is strong and the review volume adds useful statistical stability. No review text is provided to check recurring complaints or product-specific experiences.

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Value for money

92 Highest impact

Serving economics appear very strong relative to the clearly disclosed melatonin amount. The simple formula avoids paying for decorative active ingredients.

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Goals

Sleep Support
Impact
Highest effect
A Goal FitB- Strength of SupportC- CoverageA Formula Quality
Melatonin · 5 mg

Melatonin at 5 mg directly supports sleep onset and circadian timing. The capsule provides a clearly disclosed amount, though many users may need less.

The single active does not cover separate relaxation or mineral pathways. The dose may increase morning grogginess or vivid dreams, especially in sensitive users.

Study evidence
Melatonin Supportive 181 studies
General Health
Impact
Moderate effect
C+ Goal FitC Strength of SupportD- CoverageA- Formula Quality

Melatonin may support sleep timing, and reliable sleep contributes indirectly to daily resilience. The single active is plainly disclosed and the capsule format is straightforward.

The serving is above the physiologically aligned range and offers no broad nutritional support. The higher amount may increase next-day grogginess, especially for sensitive users.

Study evidence
Melatonin Supportive 69 studies
Brain Health
Impact
Moderate effect
C- Goal FitC Strength of SupportF CoverageA Formula Quality

Melatonin may help brain health indirectly when sleep timing is the limiting factor. It does not directly supply the brain with structural nutrients or a broad cognitive-support pathway.

The 5 mg capsule discloses the full amount but sits above the physiologically aligned range. A higher amount can increase next-day grogginess and impair alertness after waking.

Study evidence
Melatonin Supportive 29 studies

Ingredients

IngredientAmount per serving
Melatonin
5 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
Melatonin · 5 mg OverallScore65
F Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA+ Value

The capsule provides standard absorption, and no sustained-release technology is identified. The 5 mg dose is clearly supplied in one capsule but sits above the physiologically aligned range. Cost efficiency is strong, although independent purity certification is not provided.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis.
    Li T; Jiang S; Han M; Yang Z; Lv J; Deng C; Reiter RJ; Yang Y · Frontiers in neuroendocrinology · 2019
    Meta-analysis205 participants7 studies pooledSleep Support forMelatonin
  3. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.
    Sletten TL; Magee M; Murray JM; Gordon CJ; Lovato N; Kennaway DJ; Gwini SM; Bartlett DJ; Lockley SW; Lack LC; Grunstein RR; Rajaratnam SMW; Delayed Sleep on Melatonin (DelSoM) Study Group · PLoS medicine · 2019
    Randomized trial116 participantsSleep Support forMelatonin
  4. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  5. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  6. Effects of Melatonin Treatment on Perioperative Sleep Quality: A Systematic Review and Meta-Analysis with Trial Sequential Analysis of Randomized Controlled Trials.
    Gao Y; Chen X; Zhou Q; Song J; Zhang X; Sun Y; Yu M; Li Y · Nature and science of sleep · 2022
    Meta-analysis725 participants10 studies pooledSleep Support forMelatonin
  7. Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
    Tsukinaga A; Mihara T; Takeshima T; Tomita M; Goto T · Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Meta-analysis516 participants8 studies pooledSleep Support forMelatonin
  8. Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.
    Peltz JS; Rogge R · Sleep and biological rhythms · 2025
    Cohort study331 participantsSleep Support forMelatonin
  9. Comparative Efficacy, Tolerability, and Acceptability of Donanemab, Lecanemab, Aducanumab, Melatonin, and Aerobic Exercise for a Short Time on Cognitive Function in Mild Cognitive Impairment and Mild Alzheimer's Disease: A Systematic Review and Network Meta-Analysis.
    Terao I; Kodama W · Journal of Alzheimer's disease : JAD · 2024
    Meta-analysis4,599 participants10 studies pooledBrain Health forMelatonin
  10. Melatonin for sleep and cognitive outcomes in older adults with cognitive impairment: a meta-analysis of randomised controlled trials.
    Mdluli NT; Banda KJ; Chang YC · Age and ageing · 2025
    Meta-analysis516 participants10 studies pooledBrain Health forMelatonin
  11. Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer's disease: a 6-month, randomized, placebo-controlled, multicenter trial.
    Wade AG; Farmer M; Harari G; Fund N; Laudon M; Nir T; Frydman-Marom A; Zisapel N · Clinical interventions in aging · 2015
    Randomized trial80 participantsBrain Health forMelatonin
  12. Early Oral Melatonin Supplementation Supports White Matter Maturation in Preterm Infants: Neuroprotective Insights of an Antioxidant Molecule.
    Garofoli F; Asteggiano C; Minniti ML; Accorsi P; Albertini R; Angelini M; Aversa S; Ballante E; Cabini RF; Caporali C; Cociglio S; Franco V; Longo S; Malerba L; Materia V; Mazzocchi L; Naboni C; Palmisani M; Pullega C; Pisoni C; Preda L; Riboli A; Risso FM; Rognone E; Savini G; Simoncelli AM; Villani P; Tzialla C; Pinelli L; Fazzi E; Chiapparini L; Borgatti R; Ghirardello S; Pichiecchio A; Orcesi S · Journal of pineal research · 2026
    Randomized trial54 participantsBrain Health forMelatonin
  13. Efficacy and Safety of Melatonin in Migraine Prophylaxis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Abouelmagd ME; Aldemerdash MA; Khatatbeh AA; Osman ASA; Abbas A; Allam S; AlEdani EM; Aldemerdash A; Monteith TS · Current pain and headache reports · 2026
    Meta-analysis788 participants9 studies pooledBrain Health forMelatonin
  14. Melatonin for preventing and treating jet lag.
    Herxheimer A; Petrie KJ · The Cochrane database of systematic reviews · 2001
    Systematic review10 studies pooledGeneral Health forMelatonin
  15. Pediatric Prolonged-Release Melatonin for Sleep in Children with Autism Spectrum Disorder: Impact on Child Behavior and Caregiver's Quality of Life.
    Schroder CM; Malow BA; Maras A; Melmed RD; Findling RL; Breddy J; Nir T; Shahmoon S; Zisapel N; Gringras P · Journal of autism and developmental disorders · 2019
    Randomized trial125 participantsGeneral Health forMelatonin
  16. Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials.
    Fatemeh G; Sajjad M; Niloufar R; Neda S; Leila S; Khadijeh M · Journal of neurology · 2022
    Meta-analysis23 studies pooledGeneral Health forMelatonin
  17. Efficacy of melatonin for chronic insomnia: Systematic reviews and meta-analyses.
    Choi K; Lee YJ; Park S; Je NK; Suh HS · Sleep medicine reviews · 2022
    Meta-analysis24 studies pooledGeneral Health forMelatonin
  18. Effectiveness of melatonin for the treatment of nocturia: a randomized controlled trial.
    Leerasiri P; Pariyaeksut P; Hengrasmee P; Asumpinwong C · International urogynecology journal · 2023
    Randomized trial60 participantsGeneral Health forMelatonin
  19. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  20. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  21. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin