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Magnesium Citrate 250 mg

4.6
★ ★ ★ ★ ★
(598 ratings)
Magnesium 250 mg
Product Image
Score86
Moderate-dose magnesium citrate in softgels combines clear labeling with good value. Citrate-related loose stools and unnecessary macronutrients are the main trade-offs.
How scoring works
Softgel
Quantity:120 Softgel(s) • (60 servings)
Goals:
Stress Relief
General Health
Energy
Digestive Health
Cardiovascular Support
Heart Health
Bone Health

Score 86

Moderate-dose magnesium citrate in softgels combines clear labeling with good value. Citrate-related loose stools and unnecessary macronutrients are the main trade-offs.
How scoring works
$17.68($0.29 per serving)
Vitacost
$ 21.27
iHerb
$ 21.33
Pure Formulas
$ 20.77
Walmart
$ 17.68
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Analysis

Two softgels provide 250 mg magnesium as citrate, along with small amounts of fat, carbohydrate, and protein. The magnesium amount is moderate and easier to fit alongside dietary intake than many 400 mg products.

Citrate has reasonable absorption and can support routine magnesium needs across energy, muscle, nerve, and general health functions. Its digestive effect may be useful for some users but undesirable for those seeking a gentler everyday form.

Sixty servings and a low serving cost make the product economical. The softgels may be easier to swallow than tablets, though they offer less dosing flexibility than a powder or liquid.

Who is it for
  • Adults comfortable with softgels
  • Users seeking broad magnesium support
  • People who can account for dietary and supplemental magnesium
Best for
  • Routine magnesium supplementation
  • Muscle, nerve, and energy support
  • Softgels dosing

Pros

  • Clearly states 250 mg magnesium
  • Moderate, flexible daily amount
  • Good value per serving
  • Sixty-serving supply

Cons

  • Citrate may be laxative
  • Softgels add calories and fat
  • No supporting cofactor
  • Requires two softgels per serving

Warnings

  • Magnesium citrate may cause loose stools or cramping in sensitive users
  • Kidney impairment can reduce clearance of supplemental magnesium
  • Take magnesium apart from tetracycline or quinolone antibiotics and bisphosphonates because it can reduce absorption

Nutrient quality

86 Highest impact

The amount avoids an obvious excessive-dose concern. Most additions serve the format, though some add limited nutritional value.

Ingredient transparency

89 Highest impact

The active magnesium amount is specifically disclosed. The serving count is supplied, but complete use directions are missing.

Customer satisfaction

83 Highest impact

The review count provides a useful base for the aggregate rating. The aggregate customer rating is solid but trails leading options.

Value for money

86 Highest impact

The supply provides excellent value per meaningful serving. Most additions have a practical role, though some add little nutritional value.

Report analysis

Goals

Impact
Highest effect
A Goal FitA Strength of SupportC CoverageA Formula Quality
Magnesium · 250 mg

Magnesium provides direct nervous-system and muscle support at a substantial daily amount. Its role in correcting inadequate magnesium intake is well established, though direct stress-relief effects vary by baseline status.

Magnesium citrate is reasonably absorbable and precisely disclosed. The chewable format adds small amounts of macronutrients but remains focused on one stress-relevant mineral.

Study evidence
Magnesium Supportive 13 studies
Impact
Highest effect
A Goal FitB+ Strength of SupportD CoverageA Formula Quality
Magnesium · 250 mg

Magnesium supports energy production, muscle function, and nervous-system balance. The clearly disclosed elemental amount is meaningful for routine supplementation.

The citrate softgel offers a reasonably absorbed form with simple dosing. Magnesium citrate may loosen stools or cause abdominal discomfort in sensitive users.

Study evidence
Magnesium Supportive 114 studies
Energy
Impact
Highest effect
B+ Goal FitA- Strength of SupportD CoverageA+ Formula Quality
Magnesium · 250 mg

Magnesium citrate supplies 250 mg of a clearly identified mineral cofactor for ATP-dependent enzymes. The focused formula reaches a meaningful supplemental amount.

The product does not support alertness or stress resilience beyond correcting low magnesium intake. Magnesium citrate may cause loose stools in sensitive users.

Study evidence
Magnesium Supportive 4 studies
Impact
High effect
B+ Goal FitA- Strength of SupportD CoverageA+ Formula Quality
Magnesium · 250 mg

Magnesium citrate may support bowel motility and softer stool, giving the product a clear but narrow digestive role. The osmotic effect of magnesium is established, although response and tolerance vary with the form and the user's baseline intake.

The clearly disclosed elemental amount is well aligned with practical daily motility support. Citrate is a suitable, soluble form for a stool-softening goal and is fully disclosed. The single-active softgel is streamlined and easy to evaluate. Citrate may cause diarrhea or cramping when the serving exceeds individual tolerance.

Study evidence
Magnesium Supportive 50 studies
Impact
High effect
B Goal FitA- Strength of SupportD+ CoverageA Formula Quality
Magnesium · 250 mg

Magnesium citrate provides focused support for vascular tone and normal cardiac electrical function. Evidence is strongest when magnesium intake or status is inadequate, and the formula does not address other major cardiovascular pathways.

The clearly disclosed elemental amount is practical, and citrate offers reasonable absorption. The single-mineral design is coherent, though citrate may cause loose stools in sensitive users.

Study evidence
Magnesium Supportive 123 studies
Impact
High effect
B- Goal FitB+ Strength of SupportD+ CoverageB+ Formula Quality
Magnesium · 250 mg

Magnesium citrate offers focused support for vascular tone and normal cardiac signaling. The formula is best viewed as a single-pathway mineral supplement rather than comprehensive heart support.

The disclosed amount is well aligned with common supplemental use and the citrate form is reasonably absorbable. Citrate can loosen stools in sensitive users, which may limit daily tolerance.

Study evidence
Magnesium Supportive 158 studies

Ingredients

IngredientAmount per serving
Calories
15 Calorie(s)
Total Fat
1 Gram(s)
Total Carbohydrates
2 Gram(s)
Protein
1 Gram(s)
Magnesium (Magnesium Citrate)
250 mg
Gluten Free Adults 18–50
Report overview
D Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyB- Value

Magnesium citrate provides moderate absorption at a well-aligned elemental amount. The single-mineral formula has no added uptake co-factors or patented processing claim. A low serving cost supports good value, although citrate may cause loose stools in sensitive users.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  2. Hospital-Acquired Dysmagnesemia and In-Hospital Mortality.
    Cheungpasitporn W; Thongprayoon C; Chewcharat A; Petnak T; Mao MA; Davis PW; Bathini T; Vallabhajosyula S; Qureshi F; Erickson SB · Medical sciences (Basel, Switzerland) · 2024
    Cohort study26,020 participantsGeneral Health forMagnesium
  3. Magpie Trial in the UK: methods and additional data for women and children at 2 years following pregnancy complicated by pre-eclampsia.
    Smyth RM; Spark P; Armstrong N; Duley L · BMC pregnancy and childbirth · 2009
    Randomized trial1,601 participantsGeneral Health forMagnesium
  4. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledGeneral Health Cardiovascular Support forMagnesium
  5. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  6. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  7. The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
    van der Schoot A; Creedon A; Whelan K; Dimidi E · Neurogastroenterology and motility · 2023
    Meta-analysis787 participants8 studies pooledDigestive Health forMagnesium
  8. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  9. Effect of the laxative magnesium oxide on gastrointestinal functional recovery in fast-track colonic resection: a double-blind, placebo-controlled randomized study.
    Andersen J; Christensen H; Pachler JH; Hallin M; Thaysen HV; Kehlet H · Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2012
    Randomized trial49 participantsDigestive Health forMagnesium
  10. Lactobacillus reuteri DSM 17938 and Magnesium Oxide in Children with Functional Chronic Constipation: A Double-Blind and Randomized Clinical Trial.
    Kubota M; Ito K; Tomimoto K; Kanazaki M; Tsukiyama K; Kubota A; Kuroki H; Fujita M; Vandenplas Y · Nutrients · 2020
    Randomized trial60 participantsDigestive Health forMagnesium
  11. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  12. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  13. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  14. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  15. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  16. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  17. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  18. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  19. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  20. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  21. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  22. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  23. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  24. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  25. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  26. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  27. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  28. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  29. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  30. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  31. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  32. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  33. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  34. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  35. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  36. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  37. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  38. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  39. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  40. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  41. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  42. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  43. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium