Product Image

Multi for Men 40+

MegaFood
4.8
★ ★ ★ ★ ★
(1656 ratings)
Iodine 150 mcg
Molybdenum 55 mcg
Choline 200 mg
Chromium 120 mcg
Vitamin K 90 mcg
Product Image
Score80
Active B vitamins, D3, natural vitamin E, bisglycinate minerals, choline, and K2 create a thoughtful men’s formula. Duplicate-looking chromium entries and the absence of magnesium reduce clarity and completeness.
How scoring works
Quantity:60 Tablet(s) • (30 servings)
Goals:
Energy
Detoxification
Heart Health

Score 80

Active B vitamins, D3, natural vitamin E, bisglycinate minerals, choline, and K2 create a thoughtful men’s formula. Duplicate-looking chromium entries and the absence of magnesium reduce clarity and completeness.
How scoring works

Also available as

1 option
120 servings 2 Tablet(s) • 120 Tablet(s) • 60 servings $55.84 ($0.93 per serving)
$30.99($1.03 per serving)
iHerb
$ 30.99
Vitacost
$ 30.99
Amazon
$ 30.99
Report prices

Analysis

Vitamin D3, natural vitamin E, active riboflavin, P-5-P, methylfolate, methylcobalamin, and several chelated minerals provide good ingredient quality. The formula is designed for broad daily coverage rather than a single nutrient goal.

The supplied chromium entries appear duplicated, magnesium is absent, and choline remains below full daily needs. These gaps materially affect how complete and transparent the product is.

The product best fits men over 40 seeking an iron-free multivitamin. Diet and any separate supplements still need to cover nutrients that are missing or only partly supplied.

Who is it for
  • Men over 40 seeking an iron-free multivitamin
  • Users who can review total nutrient intake
  • People seeking broad daily coverage
Best for
  • Active-form daily multivitamin support
  • General micronutrient coverage
  • Filling selected dietary gaps

Pros

  • Uses active B-vitamin forms
  • Includes K2 and meaningful choline
  • Well-chosen zinc and trace-mineral forms

Cons

  • Chromium total is unclear
  • No magnesium or calcium
  • Relatively high serving cost

Warnings

  • Verify the chromium total on the current label before combining products
  • Vitamin K can conflict with warfarin therapy
  • Iodine should be reviewed with thyroid conditions

Nutrient quality

91 Highest impact

Active B vitamins, methylfolate, methylcobalamin, bisglycinate minerals, vitamin D3, and menaquinone-7 are excellent forms. Vitamins, trace minerals, and choline are useful, while calcium and magnesium are absent.

.

Ingredient transparency

81 Highest impact

Forms and amounts are detailed, though repeated chromium entries complicate the total. Complete non-active ingredient details are not included in the supplied label data.

.

Customer satisfaction

72 High impact

The supplied average rating provides limited high-level context. Detailed firsthand feedback is unavailable, so recurring complaints and purpose fit cannot be assessed.

.

Value for money

71 High impact

Premium forms support quality, but the high serving cost and missing major minerals limit value. Useful core doses provide fair rather than exceptional serving value.

.
Report analysis

Goals

Energy
Essential Energy Nutrients
Energy
Impact
High effect
B+ Goal FitB- Strength of SupportC+ CoverageB Formula Quality
Iodine · 150 mcgVitamin D · 25 mcgVitamin B5 · 10 mgRiboflavin · 2 mgThiamin · 2 mgVitamin B12 · 12 mcg

Active-form B vitamins, iodine, choline, and trace minerals provide a solid nutritional foundation for metabolic and thyroid-related energy. Methylcobalamin, methylfolate, P5P, and riboflavin phosphate strengthen form quality.

Most amounts suit maintenance rather than targeted fatigue support, and no mitochondrial or alertness active is included. The product is better for covering nutrient gaps than producing a noticeable energy effect.

Study evidence
Iodine Adverse 3 studies
Riboflavin Mixed 6 studies
Detoxification
Detoxification
Impact
High effect
B- Goal FitB Strength of SupportB- CoverageC+ Formula Quality
Folate · 340 mcg DFEVitamin B12 · 12 mcgVitamin B6 · 6 mgMolybdenum · 55 mcgSelenium · 50 mcgVitamin E · 20 mgZinc · 15 mgVitamin C · 200 mgCholine · 200 mgRiboflavin · 2 mg

Molybdenum, choline, selenium, zinc, and activated B vitamins support several enzyme and liver functions. The broad formula offers foundational coverage rather than concentrated clearance support.

Clear amounts and several well-chosen forms strengthen confidence in the nutrient contribution. The many general-health ingredients reduce focus on the selected goal.

Study evidence
Choline Supportive 6 studies
Molybdenum Adverse 1 study
Selenium Supportive 10 studies
Zinc Supportive 30 studies
Heart Health
Heart Health
Impact
High effect
C Goal FitC+ Strength of SupportB- CoverageC+ Formula Quality
Vitamin K · 30 mcgVitamin B12 · 12 mcgVitamin B6 · 6 mgFolate · 340 mcg DFEVitamin D · 25 mcg

Active B-vitamin forms support homocysteine metabolism, and vitamin D3 with MK-7 offers a coherent calcium-management pathway. The MK-7 amount is too low to serve as a strong stand-alone arterial-support dose.

The broad multivitamin provides useful nutrient coverage but lacks omega-3s, magnesium, or CoQ10 for deeper cardiovascular support. Vitamin K can oppose warfarin and other vitamin K antagonists, so intake changes require supervision from the prescriber managing that medicine.

Study evidence
Folate Supportive 116 studies
Vitamin K Mixed 62 studies
Cardiovascular Support
Cardiovascular Support
Impact
Moderate effect
C Goal FitC Strength of SupportC+ CoverageC+ Formula Quality
Vitamin K · 30 mcgVitamin D · 25 mcgSelenium · 50 mcgVitamin B12 · 12 mcgVitamin B6 · 6 mgVitamin E · 20 mgFolate · 340 mcg DFENiacin · 20 mg NEVitamin C · 200 mg

Active B vitamins may support homocysteine metabolism, while vitamin D, vitamin E, zinc, and a small MK-7 amount add vascular and antioxidant support. The formula remains a broad multivitamin rather than a targeted cardiovascular product.

MK-7 is underdosed for a stand-alone arterial-calcium role, and vitamin K1 is more relevant to clotting than vascular calcium management. Vitamin K can counteract warfarin, so people using it need consistent intake and clinician-guided monitoring.

Study evidence
Folate Supportive 93 studies
Vitamin D Mixed 170 studies
Vitamin E Mixed 79 studies
Vitamin K Supportive 40 studies
Bone Health
Bone Health
Impact
Moderate effect
B- Goal FitC- Strength of SupportD+ CoverageC- Formula Quality
Vitamin K · 30 mcgVitamin D · 25 mcgCopper · 0.2 mgManganese · 1.5 mgZinc · 15 mgVitamin C · 200 mg

Vitamin D3, MK-7, zinc, copper, and manganese give the multivitamin several relevant bone-support roles. Human evidence supports these nutrient functions, but the formula supplies no calcium, magnesium, collagen, or other primary structural material.

The MK-7 amount is below a useful stand-alone range, while the many non-bone vitamins make the serving broad but shallow for this goal. Vitamin K can oppose warfarin, so people using that anticoagulant need consistent intake and prescriber-guided monitoring.

Study evidence
Copper Disputed 20 studies
Manganese Adverse 12 studies
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Zinc Supportive 33 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta Carotene)
 525 mcg RAE
Vitamin C (Ascorbic Acid)
 200 mg
Vitamin D3 (Cholecalciferol)
 25 mcg
Vitamin E (D-Alpha-Tocopherol)
 20 mg
Vitamin K (Phytonadione)
 90 mcg
Thiamin (Thiamine Hydrochloride)
 2 mg
Riboflavin (Riboflavin 5'-Phosphate Sodium)
 2 mg
Niacin (Niacinamide, S. cerevisiae)
 20 mg NE
Vitamin B6 (Pyridoxal-5-Phosphate)
 6 mg
Folate (L-5-Methyltetrahydrofolate)
 340 mcg DFE
Vitamin B12 (Methylcobalamin)
 12 mcg
Biotin
250 mcg
Pantothenic Acid (Calcium D-Pantothenate)
 10 mg
Choline (Choline Bitartrate)
 200 mg
Iodine (Iodine Glycinate)
 150 mcg
Zinc (Zinc Bisglycinate)
 15 mg
Selenium (Selenium Glycinate)
 50 mcg
Copper (Copper Bisglycinate)
 0.2 mg
Manganese (Manganese Bisglycinate)
 1.5 mg
Chromium (Chromium Glutamate, Chromium Glycinate, Chromium Nicotinate)
 120 mcg
Molybdenum (Molybdenum Bisglycinate)
 55 mcg
Vitamin K2 (Menaquinone-7)
 30 mcg
Gluten Free Men 18–50 Kosher Dairy Free Vegetarian
Report overview
Iodine (Iodine Glycinate) · 150 mcg OverallScore72
C Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The iodine source is named, but it lacks the clear absorption standing of potassium iodide or well-documented kelp. The 150 mcg serving supports daily maintenance and stays below the upper limit, with elemental intake clearly stated. High serving cost limits iodine value, although selenium partly supports the premium.

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Molybdenum (Molybdenum Bisglycinate) · 55 mcg OverallScore64
A- Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value

The bisglycinate form is a clear strength and should offer good absorption. The amount remains below the collection target, although it is comfortably within the adult safety limit. A relatively costly serving and the low molybdenum dose make it a weak value when molybdenum is the main priority.

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Choline (Choline Bitartrate) · 200 mg OverallScore62
C+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

The standard bitartrate form supports general choline intake, but it is less suited to targeted cognitive use than premium forms. The moderate elemental dose is clearly disclosed and taken in two tablets. Cost per useful choline amount is high for a basic form, so value is limited.

View ingredientView products
Loading alternative details
81 Performance

Multi for Men 40+

MegaFood
<p>Active B vitamins, methylfolate, methylcobalamin, bisglycinate minerals, vitamin D3, and vitamin K2 create a high-quality men’s multivitamin. Compared with Multi for Men 40+, its disclosed nutrient forms and ingredient balance may address the original’s missing calcium and magnesium and premium cost more directly. Calcium and magnesium are absent, though the larger package improves value compared with the smaller version.</p>
76 Performance

Men's 40+ Multivitamin

INNATE Response Formulas
<p>Active B vitamins, methylfolate, methylcobalamin, vitamin D3, vitamin K2, choline, and broad trace nutrients create a balanced men’s multi. Compared with Multi for Men 40+, its disclosed nutrient forms and ingredient balance may address the original’s missing calcium and magnesium and premium cost more directly. The premium serving cost is difficult to justify because calcium and magnesium are absent and several fermented mineral forms remain less specific than named chelates.</p>
79 Performance

One Daily Multivitamin for Men

NATURELO Premium Supplements
<p>A broad men’s multivitamin uses MK-7, methylfolate, methylcobalamin, active B6, and several chelated minerals. Compared with Multi for Men 40+, its disclosed nutrient forms and ingredient balance may address the original’s missing calcium and magnesium and premium cost more directly. Strong aggregate satisfaction and favorable serving economics support value, though the unquantified produce blend and modest calcium and magnesium add little.</p>
78 Budget

Centrum Silver Men 50+

GSK
<p>Broad maintenance nutrition provides practical daily support for older men at exceptionally low cost. Its lower recurring cost than Multi for Men 40+ improves affordability, although the intended age, sex, or life-stage fit should be checked carefully. Undisclosed chemical forms and modest mineral or specialty amounts limit quality and targeted depth.</p>
74 Budget

Chewable Perfect Kids Wild Berry

Super Nutrition SimplyOne
<p>A children’s chewable provides broad vitamin coverage and uses methylcobalamin and potassium iodide, but it also includes high preformed vitamin A and several weaker mineral forms. Its lower recurring cost than Multi for Men 40+ improves affordability, although the intended age, sex, or life-stage fit should be checked carefully. Low serving cost helps value, while tiny botanical additions and missing age directions reduce confidence.</p>
71 Budget

Vitamins D and K with Sea-lodine

Life Extension
<p>A compact vitamin D, vitamin K, and iodine formula has clear amounts but uses an unspecified vitamin K form and unusually aggressive doses. Its lower recurring cost than Multi for Men 40+ improves affordability, although the intended age, sex, or life-stage fit should be checked carefully. Strong aggregate satisfaction and a low serving cost help, though the formula is better suited to a defined need than routine use.</p>
80 Value

One Daily Multivitamin for Men

NATURELO Premium Supplements
<p>A broad men’s multivitamin uses MK-7, methylfolate, methylcobalamin, active B6, and several chelated minerals. Compared with Multi for Men 40+, the lower recurring cost and disclosed nutrient profile offer a more favorable quality-to-cost balance. Strong aggregate satisfaction and favorable serving economics support value, though the unquantified produce blend and modest calcium and magnesium add little.</p>
64 Value

Men Over 40 One Daily

MegaFood
<p>The one-daily formula covers broad maintenance needs and includes iodine plus B vitamins for basic energy metabolism. Compared with Multi for Men 40+, the lower recurring cost and disclosed nutrient profile offer a more favorable quality-to-cost balance. Vitamin K can reduce warfarin activity, so people using this anticoagulant need a medically coordinated and consistent intake.</p>
68 Value

Prenatal Once Daily

Garden of Life MyKind Organics
<p>A broad prenatal profile includes useful folate, iron, vitamin D3, and methylcobalamin. Compared with Multi for Men 40+, the lower recurring cost and disclosed nutrient profile offer a more favorable quality-to-cost balance. Vitamin K intake should stay consistent for anyone using warfarin or another vitamin K antagonist.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  2. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  3. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  4. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
    Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Meta-analysis6,759 participants19 studies pooledBone Health forVitamin K
  5. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  6. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  7. Interventions to Attenuate Cardiovascular Calcification Progression: A Systematic Review of Randomized Clinical Trials.
    Murali S; Smith ER; Tiong MK; Tan SJ; Toussaint ND · Journal of the American Heart Association · 2024
    Systematic review9,901 participants49 studies pooledCardiovascular Support forVitamin K
  8. Intake of dietary phylloquinone and menaquinones and risk of stroke.
    Vissers LE; Dalmeijer GW; Boer JM; Monique Verschuren WM; van der Schouw YT; Beulens JW · Journal of the American Heart Association · 2014
    Cohort study35,476 participantsCardiovascular Support forVitamin K
  9. Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease.
    van den Heuvel EG; van Schoor NM; Lips P; Magdeleyns EJ; Deeg DJ; Vermeer C; den Heijer M · Maturitas · 2014
    Cohort study577 participantsCardiovascular Support forVitamin K
  10. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  11. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  12. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  13. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  14. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  15. Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
    Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
    Cross-sectional study2,640 participantsBone Health forManganese
  16. The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
    Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
    Narrative reviewBone Health forManganese
  17. Associations of multiple metals with bone mineral density: A population-based study in US adults.
    Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
    Cross-sectional studyBone Health forManganese
  18. Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
    Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
    Cross-sectional study31 participantsBone Health forManganese
  19. Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
    Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
    Cross-sectional study9,732 participantsBone Health forManganese
  20. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  21. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  22. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  23. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  24. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  25. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  26. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  27. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  28. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
    Elmståhl S; Gullberg B; Janzon L; Johnell O; Elmståhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
    Cohort study6,576 participantsBone Health forZinc
  29. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
    Randomized trial147 participantsBone Health forZinc
  30. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
    Randomized trial242 participantsBone Health forZinc
  31. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
    Randomized trial60 participantsBone Health forZinc
  32. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
    Meta-analysis40 studies pooledBone Health forZinc
  33. Associations of dietary folate, vitamin B6 and B12 intake with cardiovascular outcomes in 115664 participants: a large UK population-based cohort.
    Zhang B; Dong H; Xu Y; Xu D; Sun H; Han L · European journal of clinical nutrition · 2023
    Cohort study115,664 participantsCardiovascular Support forFolate
  34. Folate, Homocysteine, and Adverse Outcomes After Ischemic Stroke.
    Shi M; Zheng J; Liu Y; Mao X; Wu X; Chu M; Niu H; Sun L; Chang X; He Y; Liu Y; Guo D; Zhang Y; Zhu Z; Zhao J · Journal of the American Heart Association · 2024
    Cohort study3,530 participantsCardiovascular Support forFolate
  35. Effect of folic acid on endothelial function following acute myocardial infarction.
    Moens AL; Claeys MJ; Wuyts FL; Goovaerts I; Van Hertbruggen E; Wendelen LC; Van Hoof VO; Vrints CJ · The American journal of cardiology · 2007
    Randomized trial40 participantsCardiovascular Support forFolate
  36. Folic acid enhances endothelial function and reduces blood pressure in smokers: a randomized controlled trial.
    Mangoni AA; Sherwood RA; Swift CG; Jackson SH · Journal of internal medicine · 2003
    Randomized trial24 participantsCardiovascular Support forFolate
  37. 5-methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia.
    Verhaar MC; Wever RM; Kastelein JJ; van Dam T; Koomans HA; Rabelink TJ · Circulation · 1998
    Non-randomized trial20 participantsCardiovascular Support forFolate
  38. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support forVitamin D
  39. A Randomized Trial of Vitamin D Supplementation on Vascular Function in CKD.
    Kumar V; Yadav AK; Lal A; Kumar V; Singhal M; Billot L; Gupta KL; Banerjee D; Jha V · Journal of the American Society of Nephrology : JASN · 2017
    Randomized trial120 participantsCardiovascular Support forVitamin D
  40. Randomized, placebo-controlled, double-blind clinical trial on the contributions of vitamin D in the control of cardiovascular risk factors, depressive symptoms and suicide risk.
    Porto C; Petribu K; Barbosa N; Magalhães R; Lira C; Porto AB; Markman-Filho B; Lordsleem A; Calado E; Magalhães J; Sougey E; Silva T; Junio A; Bandeira F; Leão R · American heart journal plus : cardiology research and practice · 2025
    Randomized trial224 participantsCardiovascular Support forVitamin D
  41. Dose responses of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency: A placebo controlled randomized trial.
    Raed A; Bhagatwala J; Zhu H; Pollock NK; Parikh SJ; Huang Y; Havens R; Kotak I; Guo DH; Dong Y · PloS one · 2017
    Randomized trial70 participantsCardiovascular Support forVitamin D
  42. Paricalcitol and endothelial function in chronic kidney disease trial.
    Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
    Randomized trial88 participantsCardiovascular Support forVitamin D
  43. Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
    Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
    Meta-analysis16 studies pooledCardiovascular Support forVitamin E
  44. Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
    Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
    Randomized trial90 participantsCardiovascular Support forVitamin E
  45. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
    Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
    Randomized trial9,541 participantsCardiovascular Support forVitamin E
  46. Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
    Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
    Cohort study34,955 participantsCardiovascular Support forVitamin E
  47. Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
    Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
    Randomized trial62 participantsCardiovascular Support forVitamin E
  48. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
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