Mitochondrial Energy Optimizer with PQQ
Life Extension
Mitochondrial Energy Optimizer with PQQ
4.5
★ ★ ★ ★ ★
(2111 ratings)
Vitamin B6 100 mg
Thiamin 150 mg
Carnosine 1000 mg
Taurine 800 mg
Score 93.0
This Life Extension supplement is a powerful blend targeting mitochondrial health, energy production, and cellular protection through key ingredients like PQQ, R-Lipoic Acid, Benfotiamine, Carnosine, and Taurine. It aims to support overall vitality, brain function, and cardiovascular health with high-quality, bioavailable forms of nutrients.
Quantity: 120 Capsule(s)Servings size: 2 Vegetarian Capsule(s) (30 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
Cognitive Support
leaderboard Score 93.0
This Life Extension supplement is a powerful blend targeting mitochondrial health, energy production, and cellular protection through key ingredients like PQQ, R-Lipoic Acid, Benfotiamine, Carnosine, and Taurine. It aims to support overall vitality, brain function, and cardiovascular health with high-quality, bioavailable forms of nutrients.
insights Analysis
Life Extension's Mitochondrial Energy Optimizer with PQQ is designed to enhance cellular energy production and protect cells from oxidative stress, addressing a wide array of health goals. It features a synergistic combination of ingredients, including PQQ for mitochondrial biogenesis, R-Lipoic Acid (Na-RALA) and Benfotiamine for metabolic and antioxidant support, and Carnosine and Taurine for cellular protection and physiological balance. The use of active B6 (Pyridoxal 5-Phosphate) further boosts its efficacy in supporting nervous system health and energy metabolism. This product stands out due to its targeted blend of premium ingredients, which are generally well-regarded in the scientific and nutritional communities for their roles in mitochondrial function and overall vitality, making it a comprehensive choice for those seeking advanced cellular support.
- Contains PQQ, a novel compound shown to promote mitochondrial biogenesis, which is crucial for cellular energy and anti-aging processes.
- Utilizes highly bioavailable and effective forms of nutrients, such as Na-RALA (R-Lipoic Acid) and Pyridoxal 5-Phosphate (active B6), ensuring better absorption and utilization by the body.
- Offers a comprehensive approach to mitochondrial health with synergistic ingredients that work together to enhance energy production, provide robust antioxidant defense, and support cellular longevity.
- The doses of key ingredients like Carnosine (1000mg) and L-Taurine (800mg) are substantial and clinically relevant, contributing effectively to their beneficial physiological effects.
- The claim for 'Testosterone Support' is not directly or strongly supported by the listed ingredients; while overall health benefits may indirectly support hormone balance, these specific ingredients are not primary testosterone boosters.
- The specialized nature and inclusion of premium ingredients contribute to a higher price point per serving compared to basic single-nutrient supplements, which might not be suitable for all consumer budgets.
- Individuals with specific medical conditions, especially those affecting blood sugar regulation (due to R-Lipoic Acid and Benfotiamine), or those taking other medications should consult a healthcare professional before use to avoid potential interactions.
- Although generally well-tolerated, some individuals may experience mild gastrointestinal upset or other sensitivities to high doses of B vitamins or alpha-lipoic acid.
$48.75($1.62 per serving)
 Vitacost | $ 48.75 | |
 iHerb | $ 51.00 | |
 Amazon | $ 82.50 |
bolt Effectiveness for goals
PQQ is recognized for its role in mitochondrial biogenesis, the process of creating new mitochondria. It also acts as an antioxidant, helping to protect existing mitochondria from oxidative stress. This dual action supports cellular energy production and overall cell vitality.
R-Lipoic Acid is a potent antioxidant that helps neutralize free radicals in both water and fat-soluble environments. It also supports the regeneration of other antioxidants, like vitamins C and E, and helps maintain healthy glucose metabolism. This broad action contributes to cellular protection and metabolic efficiency.
Benfotiamine is a fat-soluble derivative of vitamin B1 (thiamine) that is more readily absorbed than water-soluble thiamine. It supports healthy glucose metabolism by blocking pathways related to advanced glycation end products (AGEs) formation. This contributes to nerve health and the protection of delicate cellular structures.
L-Taurine functions as an antioxidant, helps regulate mineral balance within cells, and supports mitochondrial function. Carnosine is a dipeptide known for its antioxidant and anti-glycation properties, protecting proteins from damage. Together, they contribute to cellular integrity and resilience against various stressors.
Yes, PQQ and R-Lipoic Acid are often combined due to their complementary actions. PQQ supports the creation of new mitochondria, while R-Lipoic Acid acts as a powerful antioxidant and supports existing mitochondrial function. This combination is thought to provide comprehensive support for mitochondrial vitality and cellular energy.
schedule Dosage, timing & forms
Due to their roles in energy metabolism and antioxidant support, many people prefer to take supplements with PQQ and R-Lipoic Acid in the morning. This timing may help align with the body's natural energy cycles throughout the day. Taking them with food is also often recommended.
While individual tolerance varies, taking supplements containing Benfotiamine, Carnosine, and L-Taurine with food is a common practice. This can help with absorption and may minimize any potential stomach discomfort. Always follow the specific instructions on the product label.
Formulations combining PQQ, R-Lipoic Acid, and Benfotiamine are often designed for once-daily consumption. The specific dosage and frequency depend on the product's concentration and the intended health goals. Always refer to the product's suggested use.
Yes, it is common to find L-Taurine and Carnosine combined in a single supplement capsule. These ingredients are often grouped due to their complementary roles in supporting cellular health and metabolic processes. The capsule form allows for convenient delivery of multiple active compounds.
The typical daily dosage for L-Taurine in supplements commonly ranges from 500 mg to 3000 mg, depending on the specific health objectives. This broad range allows for flexibility in use based on individual needs and product formulations. It's always best to follow label recommendations.
health_and_safety Safety & interactions
PQQ is generally well-tolerated, with some individuals reporting mild headaches or insomnia. R-Lipoic acid can occasionally cause mild digestive upset, while L-Taurine is typically safe but might cause mild nausea or diarrhea in sensitive individuals. If side effects occur, they are usually mild and transient.
R-Lipoic Acid has been observed to potentially lower blood sugar levels. This effect could interact with diabetes medications, leading to a risk of hypoglycemia. Individuals managing diabetes should monitor their glucose carefully and consult with a healthcare professional before use.
L-Taurine may have a modest effect on lowering blood pressure. Individuals who are taking blood pressure medications should consult their healthcare provider. Combining L-Taurine with such medications could potentially lead to an additive effect on blood pressure reduction.
Vitamin B6 can interact with several medications, including levodopa for Parkinson's disease, phenytoin used for seizures, and phenobarbital. It may also affect the efficacy of certain antibiotics or tuberculosis medications. Consulting a healthcare professional is advisable if taking prescription drugs.
The safety of ingredients like PQQ, R-Lipoic Acid, Benfotiamine, L-Taurine, and Carnosine during pregnancy or breastfeeding has not been definitively established through extensive human studies. It is generally recommended to avoid such supplements. Always consult a healthcare professional before use if you are pregnant or breastfeeding.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B6 | 100 mg |
Sodium | 18 mg |
Carnosine | 1000 mg |
L-Taurine | 800 mg |
Benfotiamine | 150 mg |
R-Lipoic Acid | 150 mg |
PQQ (Pyrroloquinoline Quinone) Disodium Salt | 10 mg |
Categories
Thiamin 95.0
The product features Benfotiamine, which is a highly bioavailable, fat-soluble form of Vitamin B1, offering superior absorption and efficacy, especially for nerve and metabolic support, compared to conventional thiamine forms.
Vitamin B6 95.0
It contains Pyridoxal 5-Phosphate (P-5-P), the active coenzyme form of Vitamin B6, ensuring direct utilization by the body for critical metabolic and neurological functions without requiring liver conversion.
Carnosine 90.0
With a substantial dose of 1000mg, the product provides effective levels of Carnosine, known for its powerful antioxidant, anti-glycation, and cellular protective properties relevant to longevity and muscle health.
Goals
Energy 95.0
PQQ, R-Lipoic Acid, and Benfotiamine are directly involved in mitochondrial function and cellular energy production pathways, providing foundational support for sustained energy levels. Taurine also plays a role in energy metabolism.
Anti-Aging 92.0
PQQ's role in mitochondrial biogenesis and the potent antioxidant and anti-glycation properties of R-Lipoic Acid, Benfotiamine, and Carnosine directly support cellular repair, longevity, and defense against age-related damage.
Brain Health 90.0
Ingredients such as PQQ and R-Lipoic Acid are neuroprotective, while Benfotiamine supports nerve health and P-5-P B6 is vital for neurotransmitter synthesis, collectively enhancing overall brain health and function.
Recommended Alternatives
80 Value 
Benfotiamine 300 mg
Doctor's Best
4.6
★★★★★
(8890 ratings)
This alternative provides twice the dose of Benfotiamine (300mg vs 150mg) found in the original product at a significantly lower price per serving (26 vs 81). This offers a clear 'better value' for a key ingredient that supports energy, metabolism, and nerve health.
78 Value 
Benfotiamine with Thiamine
Lake Avenue Nutrition
4.7
★★★★★
(819 ratings)
Offering 250mg of Benfotiamine (more than the original) at a very low price per serving (23 vs 81), this product delivers excellent value for those seeking the specific benefits of Benfotiamine for energy and nerve support. The added Thiamine further enhances its metabolic contribution.
70 Value 
Vitamin B-6 50 mg
Nature's Way
4.8
★★★★★
(1720 ratings)
This product provides the active P5P form of Vitamin B6 at 50mg, at an extremely low price per serving (6 cents). While the dose is half of the original, its exceptional cost-effectiveness for a high-quality, bioavailable form of B6 makes it an outstanding value for brain, mood, and metabolic support.
78 Performance 
Anti-Alcohol HepatoProtection Complex
Life Extension
4.5
★★★★★
(3351 ratings)
This product from the same brand offers a significantly higher dose of Benfotiamine (600mg vs 150mg), directly enhancing its benefits for metabolic health, nerve support, and anti-glycation effects, which aligns with several goals of the original product. Although marketed for liver, Benfotiamine's core actions make it a potent alternative for energy and cellular protection.
85 Performance 
Two-Per-Day Capsules
Life Extension
4.7
★★★★★
(85932 ratings)
From the same reputable brand, this comprehensive multivitamin offers a broad spectrum of essential vitamins and minerals, including high doses of B vitamins (75mg B1, 75mg B6), to holistically support energy, brain, cardiovascular, and general health. It covers many of the original product's goals in a more complete manner at a much lower price per serving.
75 Performance 
B-Complex '100'
Solgar
4.7
★★★★★
(15200 ratings)
This Solgar B-Complex '100' provides high potencies of multiple B vitamins, including 100mg of both B1 and B6, which are foundational for energy production, brain health, and metabolism. While it doesn't contain Benfotiamine or Carnosine, its comprehensive B-vitamin profile from a trusted brand offers strong support for the core energy and brain goals at a more accessible price point.
75 Budget 
Benfotiamine 300 mg
Lake Avenue Nutrition
4.7
★★★★★
(1525 ratings)
This product offers a higher dose of Benfotiamine (300mg vs 150mg) at a significantly lower price per serving (23 vs 81), providing enhanced support for nerve and metabolic health at a fraction of the cost for a key ingredient.
70 Budget 
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
4.8
★★★★★
(1062 ratings)
This alternative provides the active Pyridoxal 5-Phosphate (P5P) form of Vitamin B6 at a substantially lower price per serving (8 vs 81). While the dose is lower, it offers targeted brain and mood support from a high-quality B6 form at an exceptional value.
60 Budget 
B-50
NOW
4.7
★★★★★
(33178 ratings)
This NOW B-50 Complex offers foundational B vitamins, including Thiamine (B1) and Pyridoxine HCl (B6), at an incredibly low price per serving (7 vs 81). While not providing the advanced forms or Carnosine, it's a very cost-effective way to get essential B vitamins for general energy and metabolism.
80 Value
Benfotiamine 300 mg
Doctor's Best
4.6
★★★★★
(8890 ratings)
This alternative provides twice the dose of Benfotiamine (300mg vs 150mg) found in the original product at a significantly lower price per serving (26 vs 81). This offers a clear 'better value' for a key ingredient that supports energy, metabolism, and nerve health.
78 Value
Benfotiamine with Thiamine
Lake Avenue Nutrition
4.7
★★★★★
(819 ratings)
Offering 250mg of Benfotiamine (more than the original) at a very low price per serving (23 vs 81), this product delivers excellent value for those seeking the specific benefits of Benfotiamine for energy and nerve support. The added Thiamine further enhances its metabolic contribution.
70 Value
Vitamin B-6 50 mg
Nature's Way
4.8
★★★★★
(1720 ratings)
This product provides the active P5P form of Vitamin B6 at 50mg, at an extremely low price per serving (6 cents). While the dose is half of the original, its exceptional cost-effectiveness for a high-quality, bioavailable form of B6 makes it an outstanding value for brain, mood, and metabolic support.
78 Performance
Anti-Alcohol HepatoProtection Complex
Life Extension
4.5
★★★★★
(3351 ratings)
This product from the same brand offers a significantly higher dose of Benfotiamine (600mg vs 150mg), directly enhancing its benefits for metabolic health, nerve support, and anti-glycation effects, which aligns with several goals of the original product. Although marketed for liver, Benfotiamine's core actions make it a potent alternative for energy and cellular protection.
85 Performance
Two-Per-Day Capsules
Life Extension
4.7
★★★★★
(85932 ratings)
From the same reputable brand, this comprehensive multivitamin offers a broad spectrum of essential vitamins and minerals, including high doses of B vitamins (75mg B1, 75mg B6), to holistically support energy, brain, cardiovascular, and general health. It covers many of the original product's goals in a more complete manner at a much lower price per serving.
75 Performance
B-Complex '100'
Solgar
4.7
★★★★★
(15200 ratings)
This Solgar B-Complex '100' provides high potencies of multiple B vitamins, including 100mg of both B1 and B6, which are foundational for energy production, brain health, and metabolism. While it doesn't contain Benfotiamine or Carnosine, its comprehensive B-vitamin profile from a trusted brand offers strong support for the core energy and brain goals at a more accessible price point.