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Magnesium L-Threonate

4.6
★ ★ ★ ★ ★
(2512 ratings)
Magnesium 48 mg
Product Image
Score82
A clearly disclosed specialty threonate product, best for form-specific use rather than high-dose magnesium repletion.
How scoring works
Capsule
Quantity:90 Capsule(s) • (90 servings)
Goals:
Stress Relief
Energy
Heart Health
General Health
Cardiovascular Support

Score 82

A clearly disclosed specialty threonate product, best for form-specific use rather than high-dose magnesium repletion.
How scoring works
$35.19($0.39 per serving)
iHerb
$ 43.29
Amazon
$ 35.19
Walmart
$ 43.29
iHerb
$ 43.29
iHerb
$ 43.29
Report prices

Analysis

Magnesium L-threonate is a specialized form for users who specifically value this delivery approach. The branded material and elemental yield are both clearly identified.

The listed elemental magnesium amount is low compared with products intended for broad daily repletion. It therefore provides less support for correcting low intake even though the source quality is well defined.

The formula is focused and reasonably valued for a branded specialty ingredient. Users should confirm how the serving relates to the divided daily schedule before comparing total intake.

Who is it for
  • Adults specifically seeking magnesium L-threonate
  • Users who value a branded magnesium source
  • People who do not need a high elemental amount
Best for
  • Specialized threonate supplementation
  • Low-amount magnesium use
  • Users prioritizing form identity

Pros

  • Uses branded Magtein L-threonate
  • Clear elemental yield
  • Focused single-ingredient design

Cons

  • Low elemental magnesium amount
  • Not well suited to broad repletion
  • Full-day serving interpretation is unclear

Warnings

  • Confirm the stated amount against the full divided daily schedule
  • Do not assume the compound weight equals elemental magnesium
  • Impaired kidney function can increase magnesium accumulation risk

Nutrient quality

77 High impact

Patented Magtein magnesium L-threonate provides the main quality signal, while a low elemental magnesium amount shapes likely usefulness. Absorption, tolerability, and the formula's focus determine the main trade-off.

Ingredient transparency

87 Highest impact

Active amounts are clearly disclosed, and no proprietary blend hides the total formula. Specific ingredient names make the core actives reasonably easy to assess.

Customer satisfaction

88 Highest impact

The high average rating is supported by substantial review volume. No specific review comments are supplied, so repeated complaints and purpose alignment cannot be confirmed directly.

Value for money

74 High impact

Value is reasonable for the form quality and disclosed amount. The focused formula avoids paying for token extras, while category competitiveness depends on absorption quality.

Report analysis

Goals

Stress Relief
Stress Relief
Impact
High effect
B Goal FitC+ Strength of SupportC- CoverageA+ Formula Quality
Magnesium · 670 mg

Magnesium L-threonate offers targeted nervous-system support in a premium, well-identified form. The listed elemental amount is modest, so the full divided schedule matters for meaningful intake.

Its focused design avoids unrelated ingredients and suits people seeking a single foundational mineral. Evidence for stress support is reasonable but less direct for this form than its evidence for magnesium delivery and cognition.

Study evidence
Magnesium Supportive 13 studies
Energy
Energy
Impact
High effect
B+ Goal FitC- Strength of SupportD CoverageA- Formula Quality
Magnesium · 670 mg

Magnesium is required for ATP-dependent enzymes, and patented Magtein provides a well-characterized L-threonate form. The stated elemental amount is far below the targeted level for broad magnesium energy support.

The split capsule schedule may supply more material than the listed serving, but the provided elemental yield remains unclear for the full day. The formula is better aligned with specialized magnesium delivery than with a strong energy dose.

Study evidence
Magnesium Supportive 4 studies
Heart Health
Heart Health
Impact
High effect
B+ Goal FitC- Strength of SupportF CoverageA+ Formula Quality
Magnesium · 670 mg

Magnesium supports vascular tone, cardiac rhythm, and blood-pressure regulation, especially when intake is insufficient. Patented Magtein is a high-quality form, yet the supplied 48 mg elemental amount is low and the afternoon-plus-evening schedule makes total intake less direct.

The single-mineral design provides depth in one pathway but does not cover lipids, nitric oxide, or cardiac energy. The low elemental yield limits its likely cardiovascular contribution despite the premium form.

Study evidence
Magnesium Supportive 158 studies
General Health
General Health
Impact
High effect
B+ Goal FitC- Strength of SupportD- CoverageA- Formula Quality
Magnesium · 670 mg

Magtein magnesium L-threonate uses a premium, clearly identified form of a foundational mineral. Magnesium supports many metabolic and nervous-system processes, but the listed 48 mg elemental amount is modest.

The formula is better suited to targeted use of this specialized form than to broadly replenishing daily magnesium. Dose instructions span multiple capsules, so users should confirm whether the stated amount applies to the full daily schedule.

Study evidence
Magnesium Supportive 114 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B+ Goal FitD+ Strength of SupportF CoverageA+ Formula Quality
Magnesium · 670 mg

Magnesium supports vascular relaxation and stable heart rhythm, but the listed elemental amount is modest. The patented threonate form is better known for brain delivery than for efficient cardiovascular magnesium repletion.

Clear labeling and branded material support quality confidence, while the low elemental yield limits practical impact on this goal. The focused formula may suit users prioritizing threonate, but it is not a strong standalone cardiovascular magnesium dose.

Study evidence
Magnesium Supportive 123 studies
Bone Health
Bone Health
Impact
Moderate effect
C Goal FitC- Strength of SupportF CoverageB Formula Quality
Magnesium · 670 mg

Magnesium supports bone mineral structure and vitamin D activation, but the listed elemental amount is low for skeletal nutrition. Patented Magtein provides strong form identification yet is positioned more often for neurological delivery than comprehensive bone support.

No calcium, vitamin D, vitamin K, or protein-matrix ingredient broadens the formula. The focused design is clean, but its low mineral yield limits practical contribution to bone health.

Study evidence
Magnesium Supportive 48 studies

Ingredients

IngredientAmount per serving
Magnesium (Magtein Magnesium L-Threonate)
 48 mg
Magtein Magnesium L-Threonate
670 mg
Adults 18–50
Report overview
Magnesium (Magtein Magnesium L-Threonate) · 48 mg OverallScore88
A+ Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyA+ Value

Patented Magtein magnesium L-threonate provides a premium form with strong quality assurance. The listed 48 mg elemental amount is well below the studied daily target and may require the full multi-capsule schedule to approach it. Its below-median listed serving cost offers strong form-based value, though dose interpretation matters.

View ingredientView products
Loading alternative details
91 Performance

Krebs Magnesium Potassium Complex

Nature's Way
<p>Magnesium lysinate and malate provide favorable forms at a useful 250 mg amount, with 95 mg potassium citrate for broader mineral support. Compared with the original 48 mg amount from Magtein Magnesium L-Threonate, the form disclosure is clearer and the dose is less aggressive for many users.</p>
88 Performance

Magnesium Bisglycinate Powder

NOW
<p>The pure powder provides 250 mg magnesium bisglycinate in a well-absorbed, adjustable form. It is better suited to general magnesium repletion than the original specialty threonate product, but it does not preserve that form-specific purpose.</p>
85 Performance

Magnesium Bisglycinate Chelate

Healthy Origins
<p>The clean powder uses TRAACS magnesium bisglycinate at a practical 200 mg elemental amount. Compared with the original 48 mg amount from Magtein Magnesium L-Threonate, it prioritizes absorption quality and moderate dosing, although it may provide less total magnesium.</p>
83 Budget

Magnesium Citrate Pure Powder

Best Naturals
<p>The lower-cost powder provides 210 mg magnesium citrate in an adjustable serving. Compared with the original 48 mg amount from Magtein Magnesium L-Threonate, citrate is clearly identified and generally useful for routine repletion, though it may loosen stools.</p>
80 Budget

Magnesium Caps 500 mg

Life Extension
<p>The lower-cost blend supplies 500 mg magnesium across citrate, succinate, glycinate, and oxide sources. It offers a substantial amount for the cost, but oxide lowers average absorption quality and the high serving may cause diarrhea or cramping compared with the original 48 mg amount from Magtein Magnesium L-Threonate.</p>
84 Budget

Potassium + Magnesium

Nutricost
<p>The lower-cost two-mineral formula supplies 210 mg magnesium citrate with 99 mg potassium citrate. It offers clear mineral forms and practical value, although its magnesium amount may be lower than the original 48 mg amount from Magtein Magnesium L-Threonate.</p>
85 Value

Magnesium Bisglycinate 200 mg

Natural Factors
<p>The focused powder combines 200 mg magnesium bisglycinate with a moderate serving cost and a nonaggressive dose. Compared with the original 48 mg amount from Magtein Magnesium L-Threonate, the clearly named form improves quality-to-cost balance while reducing the chance of dose-related digestive discomfort.</p>
85 Value

Cal/Mag 500 mg/250 mg

NaturesPlus
<p>The formula pairs 250 mg chelated magnesium with 500 mg chelated calcium in an economical serving. It adds useful bone-mineral breadth and clear forms compared with the original 48 mg amount from Magtein Magnesium L-Threonate, though calcium may be unnecessary for users seeking magnesium alone.</p>
81 Value

Ultra-Mag

Source Naturals
<p>The broad blend supplies 400 mg magnesium from citrate, glycinate, malate, succinate, and taurinate forms at a favorable serving cost. Form diversity improves practical value compared with the original 48 mg amount from Magtein Magnesium L-Threonate, while the high amount and 30 mg vitamin B6 may reduce suitability for long-term routine use.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  2. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  3. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  4. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  5. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  6. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  7. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  8. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  9. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  10. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  11. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  12. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  13. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  14. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  15. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  16. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  17. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  18. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  19. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  20. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  21. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  22. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  23. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  24. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  25. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  26. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  27. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  28. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  29. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  30. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  31. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  32. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  33. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  34. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  35. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  36. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  37. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium