Product Image

Neurolink

Designs for Health
4.8
★ ★ ★ ★ ★
(11 ratings)
GABA 750 mg
Tyrosine 1200 mg
Taurine 600 mg
Glutamine 600 mg
5-HTP 150 mg
Product Image
Score66
A potent, fully disclosed neurotransmitter blend offers broad mood and stress support. High cost, mixed activation and calming, and serious serotonin interactions require caution.
How scoring works
Quantity:180 Capsule(s) • (30 servings)
Goals:
Mood Support
Brain Health
Sleep Support
Stress Relief

Score 66

A potent, fully disclosed neurotransmitter blend offers broad mood and stress support. High cost, mixed activation and calming, and serious serotonin interactions require caution.
How scoring works
$72.99($2.43 per serving)
Pure Formulas
$ 72.99
Report prices

Analysis

L-tyrosine at 1,200 mg and GABA at 750 mg are substantial amounts, while 5-HTP at 150 mg adds a strong serotonin precursor. Taurine, inositol, glutamine, and P5P broaden the neurotransmitter and amino-acid support.

The formula combines activating tyrosine with GABA and 5-HTP, so the intended effect may vary by user and timing. Glutamine and taurine are useful supporting amounts but remain below focused standalone doses.

All active amounts are clearly disclosed, yet six capsules and a high serving cost reduce convenience and value. The 5-HTP component makes medication screening essential before use.

Who is it for
  • Adults seeking broad neurotransmitter support
  • People working with a clinician on mood or stress supplements
  • Users comfortable with a large capsule serving
Best for
  • Mood-support routines
  • Stress-related neurotransmitter support
  • Users specifically seeking tyrosine plus GABA

Pros

  • Provides substantial tyrosine and GABA
  • Includes active P5P vitamin B6
  • Fully discloses all active amounts
  • Covers several neurotransmitter pathways

Cons

  • Requires six capsules
  • High serving cost
  • Mixed stimulating and calming design
  • Glutamine and taurine are below focused doses

Warnings

  • Do not combine 5-HTP with SSRIs, SNRIs, MAO inhibitors, tramadol, or other serotonergic medicines because excess serotonin can cause a serious reaction
  • Tyrosine can interact with MAO inhibitors and thyroid medicines
  • GABA and 5-HTP may cause drowsiness; avoid driving until individual response is known
  • The 30 mg vitamin B6 serving is high enough that total long-term B6 intake should be monitored

Nutrient quality

73 High impact

Active vitamin B6 and standard amino acids are clearly identified, although premium source details are absent. Tyrosine, GABA, inositol, taurine, and 5-HTP are substantial, while glutamine remains modest for its usual uses.

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Ingredient transparency

81 Highest impact

Active amounts are stated and no proprietary blend hides a core dose. Missing excipient details and complete use directions leave the supplied label information incomplete.

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Customer satisfaction

59 Moderate impact

The supplied aggregate satisfaction average provides a broad signal, while the response volume determines how stable it appears. No comment-level evidence is available to assess repeated complaints or confirm intended-use experiences.

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Value for money

43 Lower impact

Quality, safety trade-offs, or serving economics materially weaken value. Most ingredients contribute to the neurotransmitter design, though the breadth reduces focus.

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Report analysis

Goals

Mood Support
Mood Support
Impact
Highest effect
B+ Goal FitA Strength of SupportA CoverageA- Formula Quality
Vitamin B6 · 30 mg5-HTP · 150 mg

5-HTP, tyrosine, active vitamin B6, GABA, taurine, and inositol address several neurotransmitter pathways relevant to mood. The broad design is compelling, but evidence for oral GABA and the full combination is less certain than evidence for its lead precursors.

5-HTP, tyrosine, and GABA reach substantial amounts, and P5P provides a useful cofactor. 5-HTP can interact with antidepressants and other serotonergic medicines, while tyrosine warrants care with monoamine oxidase inhibitors.

Study evidence
5-HTP Supportive 9 studies
GABA Supportive 12 studies
Vitamin B6 Supportive 19 studies
Brain Health
Brain Health
Impact
Highest effect
B+ Goal FitB+ Strength of SupportA- CoverageC+ Formula Quality
Vitamin B6 · 30 mg

A strong tyrosine amount supports catecholamine production, while active B6, taurine, inositol, GABA, and 5-HTP address several neurotransmitter pathways. Every active amount is clearly stated and the main ingredients reach meaningful levels.

Combining a catecholamine precursor with GABA and 5-HTP creates a mixed stimulating and calming design rather than a single clear cognitive outcome. The 5-HTP can increase serotonin and should not be combined casually with serotonergic medicines such as SSRIs or MAO inhibitors.

Study evidence
Tyrosine Supportive 7 studies
Sleep Support
Sleep Support
Impact
High effect
B- Goal FitA- Strength of SupportA- CoverageB- Formula Quality

GABA, 5-HTP, taurine, and inositol provide substantial support for inhibitory and serotonin-related pathways. Active vitamin B6 helps support neurotransmitter metabolism.

A large tyrosine amount may feel activating and weakens the nighttime logic of the formula. The 5-HTP component should not be combined with SSRIs, SNRIs, MAO inhibitors, or other serotonergic medicines because excess serotonin can cause a serious reaction.

Study evidence
5-HTP Supportive 1 study
GABA Supportive 4 studies
Taurine Not classified

No linked studies yet.

Vitamin B6 Disputed 7 studies
Stress Relief
Stress Relief
Impact
High effect
B+ Goal FitB+ Strength of SupportA- CoverageC Formula Quality
GABA · 750 mgVitamin B6 · 30 mg

GABA, taurine, inositol, active vitamin B6, and 5-HTP address several calming neurotransmitter pathways. Most ingredient amounts are fully disclosed and several reach substantial levels.

High-dose tyrosine pulls toward activation and sits awkwardly beside the calming and serotonin-support ingredients. The 5-HTP should not be combined with SSRIs, SNRIs, MAO inhibitors, or other serotonergic medicines because excess serotonin can cause a serious reaction.

Study evidence
5-HTP Supportive 18 studies
GABA Supportive 6 studies
Taurine Supportive 5 studies
Vitamin B6 Supportive 10 studies
Fitness
Fitness
Impact
Moderate effect
D- Goal FitC Strength of SupportC- CoverageB- Formula Quality

Tyrosine, taurine, glutamine, and related compounds form a neurotransmitter-focused blend rather than a clear performance formula. Some ingredients may support focus or fatigue indirectly, but direct exercise benefits are limited.

Several amounts fall below common performance-use levels, and 5-hydroxytryptophan may interact with serotonergic medicines. The formula is transparent yet poorly aligned with power, endurance, or recovery outcomes.

Study evidence
Taurine Supportive 21 studies
Detoxification
Detoxification
Impact
Moderate effect
D+ Goal FitC- Strength of SupportC- CoverageD+ Formula Quality
Vitamin B6 · 30 mgGlutamine · 600 mgTaurine · 600 mg

Taurine and glutamine offer plausible support for bile conjugation and the gut barrier. Their amounts are modest for focused use, and the formula is mainly built around neurotransmitter support.

Clear doses and active B6 make the label easy to judge. The included 5-HTP can dangerously increase serotonin when combined with SSRIs, SNRIs, MAO inhibitors, or other serotonergic medicines.

Study evidence
Glutamine Supportive 8 studies
Taurine Supportive 2 studies
Anti-Aging
Anti-Aging
Impact
Moderate effect
D Goal FitB- Strength of SupportC- CoverageD- Formula Quality
Taurine · 600 mg

Taurine provides some age-relevant metabolic and cellular support, while the broader formula targets neurotransmitter pathways. Several amino acids are disclosed at substantial amounts.

The taurine amount is modest for a focused longevity role, and most ingredients are not specific to healthy aging. The included 5-HTP can interact dangerously with serotonergic medicines such as SSRIs, SNRIs, and MAO inhibitors.

Study evidence
Taurine Supportive 3 studies

Ingredients

IngredientAmount per serving
Vitamin B-6 (Pyridoxal 5-Phosphate)
 30 mg
L-Tyrosine
1200 mg
GABA
750 mg
L-Glutamine
600 mg
Inositol
600 mg
Taurine
600 mg
5-HTP
150 mg
Gluten Free Adults 18–50
Report overview
GABA · 750 mg OverallScore75
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyD- Value

The fully disclosed 750 mg GABA dose is well aligned with the collection, although its source is not identified as a premium fermented form. Capsule delivery is practical, while the supporting amino acids and nutrients make it a broad combination rather than a focused GABA option. The high cost per serving sharply limits value despite the substantial dose.

View ingredientView products
Tyrosine · 1200 mg OverallScore70
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The L-tyrosine amount is well aligned with acute cognitive-support use and is disclosed clearly. Raw-material purity or sourcing details are absent, while the multi-ingredient formula makes tyrosine-specific value poor. The included 5-HTP can raise serotonin, creating a meaningful interaction concern with serotonergic medicines such as SSRIs or MAO inhibitors.

View ingredientView products
Taurine · 600 mg OverallScore50
C- Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyF Value

The 600 mg taurine amount supports general maintenance but remains below the higher-potency target. Generic taurine lacks free-form, purity-grade, sourcing, and testing details, and the amount is stated only for two capsules. The formula also contains 5-HTP, which should not be combined with SSRIs, SNRIs, MAO inhibitors, or other serotonergic medicines because excess serotonin can cause a serious reaction.

View ingredientView products
Loading alternative details
71 Performance

NeuroCalm

Designs for Health
Active B6, glycinate magnesium, PharmaGABA, theanine, taurine, chamomile, and 50 mg of 5-HTP is better targeted than the original's high-dose B6, serotonergic 5-HTP risk, and burdensome six-capsule serving. The lower B6 amount and branded ingredients improve long-term fit and disclosure; 5-HTP can still interact with serotonin-raising medicines.
77 Performance

Neuro Optimizer

Jarrow Formulas
Acetyl-L-carnitine, citicoline, phosphatidylserine, glutamine, and taurine is better targeted than the original's high-dose B6, serotonergic 5-HTP risk, and burdensome six-capsule serving. The cognitive ingredients are supplied at meaningful, clearly stated amounts; the formula does not directly replace the original calming and serotonin-focused ingredients.
82 Performance

Theanine Serene

Source Naturals
Chelated magnesium, 500 mg of GABA, 450 mg of taurine, 200 mg of theanine, and holy basil is better targeted than the original's high-dose B6, serotonergic 5-HTP risk, and burdensome six-capsule serving. The fully disclosed amounts create a coherent non-serotonergic relaxation blend; botanical standardization and exact mineral-chelate details are not provided.
77 Budget

True Calm

NOW
GABA, glycine, taurine, inositol, valerian, and a moderate B6 amount costs less per serving while keeping the formula relevant to the original's goals. The formula preserves a broad calming amino-acid approach with very efficient serving value; most ingredients are modest and only GABA makes a notable contribution.
78 Budget

GABAplex

Swanson
GABA, glycine, tyrosine, taurine, and theanine costs less per serving while keeping the formula relevant to the original's goals. The blend covers calm and stress support with a much easier serving cost; theanine, tyrosine, and taurine are modest, and black pepper may affect medicine absorption.
82 Budget

Theanine Serene

Source Naturals Serene Science
Chelated magnesium, 500 mg of GABA, 450 mg of taurine, 200 mg of theanine, and holy basil costs less per serving while keeping the formula relevant to the original's goals. Clear, meaningful amounts support relaxation and stress resilience without 5-HTP; the exact magnesium chelate and holy basil standardization are not disclosed.
79 Value

Superior Sleep

Doctor's Best
Sensoril ashwagandha, 200 mg of theanine, GABA, melatonin, and 5-HTP offers a more balanced mix of ingredient quality and serving value than the original's high-dose B6, serotonergic 5-HTP risk, and burdensome six-capsule serving. The compact blend supplies several sleep and stress ingredients at meaningful amounts; 5-HTP has serotonergic interaction risk and 5 mg of melatonin may cause morning grogginess.
77 Value

Sleep Support

The Vitamin Shoppe
200 mg of theanine, 250 mg of GABA, valerian, 5-HTP, and melatonin offers a more balanced mix of ingredient quality and serving value than the original's high-dose B6, serotonergic 5-HTP risk, and burdensome six-capsule serving. The sleep-oriented actives provide more focused nighttime coverage; the 5-HTP amount is aggressive and can interact with serotonin-raising medicines.
77 Value

NightRest with Melatonin

Source Naturals
Magnesium, 500 mg of GABA, taurine, glycine, calming herbs, and melatonin offers a more balanced mix of ingredient quality and serving value than the original's high-dose B6, serotonergic 5-HTP risk, and burdensome six-capsule serving. The broad sleep formula uses meaningful amounts and has efficient serving economics; 5 mg of melatonin may cause next-day drowsiness in sensitive users.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands--A review.
    Jongkees BJ; Hommel B; Kühn S; Colzato LS · Journal of psychiatric research · 2016
    Narrative reviewBrain Health forTyrosine
  2. Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating.
    Jongkees BJ · Cognitive, affective & behavioral neuroscience · 2021
    Randomized trial45 participantsBrain Health forTyrosine
  3. Dietary Tyrosine Intake (FFQ) Is Associated with Locus Coeruleus, Attention and Grey Matter Maintenance: An MRI Structural Study on 398 Healthy Individuals of the Berlin Aging Study-II.
    Plini ERG; Melnychuk MC; Harkin A; Dahl MJ; McAuslan M; Kühn S; Boyle RT; Whelan R; Andrews R; Düzel S; Drewelies J; Wagner GG; Lindenberger U; Norman K; Robertson IH; Dockree PM · The journal of nutrition, health & aging · 2023
    Cross-sectional study398 participantsBrain Health forTyrosine
  4. Taurine supplementation reduces myeloperoxidase and matrix-metalloproteinase-9 levels and improves the effects of exercise in cognition and physical fitness in older women.
    Chupel MU; Minuzzi LG; Furtado GE; Santos ML; Ferreira JP; Filaire E; Teixeira AM · Amino acids · 2021
    Randomized trial48 participantsAnti-Aging forTaurine
  5. Taurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70.
    Abud GF; De Carvalho FG; Batitucci G; Travieso SG; Bueno Junior CR; Barbosa Junior F; Marchini JS; de Freitas EC · Nutrition (Burbank, Los Angeles County, Calif.) · 2022
    Randomized trial24 participantsAnti-Aging forTaurine
  6. Association of taurine intake with changes in physical fitness among community-dwelling middle-aged and older Japanese adults: an 8-year longitudinal study.
    Domoto T; Kise K; Oyama Y; Furuya K; Kato Y; Nishita Y; Kozakai R; Otsuka R · Frontiers in nutrition · 2024
    Cohort studyAnti-Aging forTaurine
  7. Combined L-carnosine and L-tyrosine supplementation as an ergogenic strategy for physical and cognitive performance under fatigue in professional football players.
    Bilgin S; Bozyılan E; Buzdağlı Y; Karaç Öcal Y; Gürkan O; Toktaş S; İnan H; Egil İ; Yarayan YE · Frontiers in nutrition · 2026
    Randomized trial24 participantsBrain Health forTyrosine
  8. Influence of nutritional tyrosine on cognition and functional connectivity in healthy old humans.
    Hensel C; Becker M; Düzel S; Demuth I; Norman K; Steinhagen-Thiessen E; Gallinat J; Lindenberger U; Kühn S · NeuroImage · 2019
    Cross-sectional study286 participantsBrain Health forTyrosine
  9. Efficacy of glutamine supplementation in postoperative patients undergoing hepatic surgery: a systematic review and meta-analysis of randomized controlled trials.
    Meng X; Zhang M; Wang X · Clinics (Sao Paulo, Brazil) · 2026
    Meta-analysis1,198 participants18 studies pooledDetoxification forGlutamine
  10. Glutamine supplementation in preterm infants receiving parenteral nutrition leads to an early improvement in liver function.
    Wang Y; Cai W; Tao YX; Tang QY; Feng Y; Wu J · Asia Pacific journal of clinical nutrition · 2014
    Randomized trial30 participantsDetoxification forGlutamine
  11. Parenteral glutamine protects hepatic function during bone marrow transplantation.
    Brown SA; Goringe A; Fegan C; Davies SV; Giddings J; Whittaker JA; Burnett AK; Poynton CH · Bone marrow transplantation · 1998
    Randomized trial34 participantsDetoxification forGlutamine
  12. Protective effect of parenteral glutamine supplementation on hepatic function in very low birth weight infants.
    Wang Y; Tao YX; Cai W; Tang QY; Feng Y; Wu J · Clinical nutrition (Edinburgh, Scotland) · 2010
    Randomized trial30 participantsDetoxification forGlutamine
  13. A multistrain probiotic increases the serum glutamine/glutamate ratio in patients with cirrhosis: a metabolomic analysis.
    Laghi L; Román E; Lan Q; Nieto JC; Canalda-Baltrons A; Poca M; Sánchez-Rodríguez MB; Clària J; Alvarado E; Cuyàs B; Sánchez E; Vidal S; Guarner C; Escorsell À; Manichanh C; Soriano G · Hepatology communications · 2023
    Randomized trial32 participantsDetoxification forGlutamine
  14. Dietary amino acid taurine ameliorates liver injury in chronic hepatitis patients.
    Hu YH; Lin CL; Huang YW; Liu PE; Hwang DF · Amino acids · 2008
    Non-randomized trial24 participantsDetoxification forTaurine
  15. Taurine status and response to intravenous taurine supplementation in adults with short-bowel syndrome undergoing long-term parenteral nutrition: a pilot study.
    Schneider SM; Joly F; Gehrardt MF; Badran AM; Myara A; Thuillier F; Coudray-Lucas C; Cynober L; Trivin F; Messing B · The British journal of nutrition · 2006
    Single-arm trial32 participantsDetoxification forTaurine
  16. Taurine supplementation enhances anaerobic power in elite speed skaters: A double-blind, randomized, placebo-controlled, crossover study.
    Buzdağlı Y; Eyipınar CD; Öget F; Şıktar E; Forbes SC; Tekin A · Biology of sport · 2023
    Randomized trial30 participantsFitness forTaurine
  17. The effect of acute taurine ingestion on 3-km running performance in trained middle-distance runners.
    Balshaw TG; Bampouras TM; Barry TJ; Sparks SA · Amino acids · 2013
    Randomized trial8 participantsFitness forTaurine
  18. Effects of different doses of taurine supplementation on repeated-sprint performance after exhaustive exercise in a high temperature and humidity environment.
    Cheng X; Lin Y; Li Z · Frontiers in nutrition · 2026
    Randomized trial16 participantsFitness forTaurine
  19. Oral taurine improves critical power and severe-intensity exercise tolerance.
    Waldron M; Patterson SD; Jeffries O · Amino acids · 2020
    Randomized trial12 participantsFitness forTaurine
  20. Acute taurine supplementation enhances thermoregulation and endurance cycling performance in the heat.
    Page LK; Jeffries O; Waldron M · European journal of sport science · 2019
    Randomized trial11 participantsFitness forTaurine
  21. Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
    Jangid P; Malik P; Singh P; Sharma M; Gulia AK · Asian journal of psychiatry · 2013
    Randomized trial70 participantsMood Support for5-HTP
  22. The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
    Li S; Sutanto CN; Xia X; Kim JE · Nutrients · 2025
    Randomized trial30 participantsMood Support for5-HTP
  23. Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.
    Javelle F; Lampit A; Bloch W; Häussermann P; Johnson SL; Zimmer P · Nutrition reviews · 2020
    Meta-analysis13 studies pooledMood Support for5-HTP
  24. Tryptophan and 5-hydroxytryptophan for depression.
    Shaw K; Turner J; Del Mar C · The Cochrane database of systematic reviews · 2002
    Systematic review64 participants2 studies pooledMood Support for5-HTP
  25. 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study.
    Aliño JJ; Gutierrez JL; Iglesias ML · International pharmacopsychiatry · 1976
    Non-randomized trial30 participantsMood Support for5-HTP
  26. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
    Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
    Randomized trial63 participantsMood Support Stress Relief forGABA
  27. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
    Deligiannidis KM; Kroll-Desrosiers AR; Mo S; Nguyen HP; Svenson A; Jaitly N; Hall JE; Barton BA; Rothschild AJ; Shaffer SA · Psychoneuroendocrinology · 2017
    Cohort study56 participantsMood Support forGABA
  28. The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
    Wang J; Liu G; Xu K; Ai K; Huang W; Zhang J · Human brain mapping · 2023
    Case-control study69 participantsMood Support forGABA
  29. Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis.
    Truong V; Cheng PZ; Lee HC; Lane TJ; Hsu TY; Duncan NW · Psychiatry research. Neuroimaging · 2021
    Observational studyMood Support forGABA
  30. Systematic review of gamma-aminobutyric-acid inhibitory deficits across the reproductive life cycle.
    Vigod SN; Strasburg K; Daskalakis ZJ; Blumberger DM · Archives of women's mental health · 2014
    Systematic review11 studies pooledMood Support forGABA
  31. High Dose Vitamin B6 Reduces Depression Symptoms.
    Field DT; Cracknell R; Biagi N · Depression and anxiety · 2026
    Randomized trial267 participantsMood Support forVitamin B6
  32. Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
    Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
    Randomized trial81 participantsMood Support Stress Relief forVitamin B6
  33. Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
    Lu J; Mao H; Tan Y; Luo G · Brain and behavior · 2024
    Cross-sectional study24,683 participantsMood Support forVitamin B6
  34. Associations of dietary B vitamins intakes with depression in adults.
    Wu Y; Li S; Wang W; Zhang D · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2023
    Observational study17,732 participantsMood Support forVitamin B6
  35. Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection.
    Shor-Posner G; Feaster D; Blaney NT; Rocca H; Mantero-Atienza E; Szapocznik J; Eisdorfer C; Goodkin K; Baum MK · International journal of psychiatry in medicine · 1995
    Cohort study88 participantsMood Support forVitamin B6
  36. The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
    Sutanto CN; Xia X; Heng CW; Tan YS; Lee DPS; Fam J; Kim JE · Clinical nutrition (Edinburgh, Scotland) · 2024
    Randomized trial30 participantsSleep Support for5-HTP
  37. Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
    Byun JI; Shin YY; Chung SE; Shin WC · Journal of clinical neurology (Seoul, Korea) · 2020
    Randomized trial40 participantsSleep Support forGABA
  38. Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.
    Imafuku F; Yamamoto K; Tanaka E; Aoki R; Nishino S · Nutrients · 2023
    Randomized trial160 participantsSleep Support forGABA
  39. Reduced γ-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: a link to major depressive disorder?
    Plante DT; Jensen JE; Schoerning L; Winkelman JW · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
    Case-control study40 participantsSleep Support forGABA
  40. GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
    Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
    Randomized trial30 participantsSleep Support Stress Relief forGABA
  41. Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
    Zandifar A; Mousavi S; Schmidt NB; Badrfam R; Seif E; Qorbani M; Mehrabani Natanzi M · Journal of affective disorders · 2023
    Randomized trial66 participantsSleep Support forVitamin B6
  42. Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
    Jadidi A; Rezaei Ashtiani A; Khanmohamadi Hezaveh A; Aghaepour SM · BMC complementary medicine and therapies · 2023
    Randomized trial75 participantsSleep Support forVitamin B6
  43. Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.
    García-García C; Baik I · Nutrition research and practice · 2022
    Randomized trial47 participantsSleep Support forVitamin B6
  44. Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep.
    Adventure-Heart DJ; Madden NA; Delfabbro P · Perceptual and motor skills · 2018
    Randomized trial100 participantsSleep Support forVitamin B6
  45. The effect of pyridoxine administration on melatonin secretion in normal men.
    Luboshitzky R; Ophir U; Nave R; Epstein R; Shen-Orr Z; Herer P · Neuro endocrinology letters · 2003
    Randomized trial12 participantsSleep Support forVitamin B6
  46. Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo.
    Kahn RS; Westenberg HG; Verhoeven WM; Gispen-de Wied CC; Kamerbeek WD · International clinical psychopharmacology · 1987
    Randomized trial45 participantsStress Relief for5-HTP
  47. Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients.
    Schruers K; van Diest R; Overbeek T; Griez E · Psychiatry research · 2003
    Randomized trial48 participantsStress Relief for5-HTP
  48. Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.
    Smarius LJ; Jacobs GE; Hoeberechts-Lefrandt DH; de Kam ML; van der Post JP; de Rijk R; van Pelt J; Schoemaker RC; Zitman FG; van Gerven JM; Gijsman HJ · Journal of psychopharmacology (Oxford, England) · 2008
    Randomized trialStress Relief for5-HTP
  49. Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
    Jacobs GE; Kamerling IM; de Kam ML; Derijk RH; van Pelt J; Zitman FG; van Gerven JM · Journal of psychopharmacology (Oxford, England) · 2010
    Randomized trialStress Relief for5-HTP
  50. An open-label trial of L-5-hydroxytryptophan in subjects with romantic stress.
    Emanuele E; Bertona M; Minoretti P; Geroldi D · Neuro endocrinology letters · 2011
    Single-arm trial15 participantsStress Relief for5-HTP
  51. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
    Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H · Journal of nutritional science and vitaminology · 2011
    Clinical trial30 participantsStress Relief forGABA
  52. Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality.
    Meyerhoff DJ; Mon A; Metzler T; Neylan TC · Sleep · 2014
    Case-control study45 participantsStress Relief forGABA
  53. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsStress Relief forGABA
  54. Protective and therapeutic effectiveness of taurine supplementation plus low calorie diet on metabolic parameters and endothelial markers in patients with diabetes mellitus: a randomized, clinical trial.
    Moludi J; Qaisar SA; Kadhim MM; Ahmadi Y; Davari M · Nutrition & metabolism · 2022
    Randomized trial120 participantsStress Relief forTaurine
  55. Effects of taurine supplementation on VDT work induced visual stress.
    Zhang M; Bi LF; Ai YD; Yang LP; Wang HB; Liu ZY; Sekine M; Kagamimori S · Amino acids · 2005
    Randomized trial25 participantsStress Relief forTaurine
  56. Taurine supplementation attenuates delayed increase in exercise-induced arterial stiffness.
    Ra SG; Choi Y; Akazawa N; Ohmori H; Maeda S · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2017
    Randomized trial29 participantsStress Relief forTaurine
  57. Correlations between dietary taurine intake and life stress in Korean college students.
    Sung MJ; Chang KJ · Advances in experimental medicine and biology · 2009
    Observational studyStress Relief forTaurine
  58. Profiling inflammatory and oxidative stress biomarkers following taurine supplementation: a systematic review and dose-response meta-analysis of controlled trials.
    Faghfouri AH; Seyyed Shoura SM; Fathollahi P; Shadbad MA; Papi S; Ostadrahimi A; Faghfuri E · European journal of clinical nutrition · 2022
    Meta-analysisStress Relief forTaurine
  59. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forVitamin B6
  60. RENAL PROTECTIVE EFFECT AND CLINICAL ANALYSIS OF VITAMIN B 6 IN PATIENTS WITH SEPSIS.
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    Randomized trial128 participantsStress Relief forVitamin B6
  61. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial.
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    Randomized trial264 participantsStress Relief forVitamin B6
  62. Associations between dietary intake of B-vitamins and psychological disorders among Iranian women: a cross-sectional study.
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    Cross-sectional study447 participantsStress Relief forVitamin B6