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Magnesium Malate Chelate

4.8
★ ★ ★ ★ ★
(79 ratings)
Magnesium 500 mg
Product Image
Score75
Strong malate and glycinate forms support good absorption potential, but 500 mg is an aggressive serving. Missing form proportions and premium cost are the other key trade-offs.
How scoring works
Tablet
Quantity:240 Tablet(s) • (120 servings)
Goals:
General Health
Heart Health
Stress Relief
Cardiovascular Support
Energy
Bone Health
Testosterone Support

Score 75

Strong malate and glycinate forms support good absorption potential, but 500 mg is an aggressive serving. Missing form proportions and premium cost are the other key trade-offs.
How scoring works
$55.99($0.46 per serving)
iHerb
$ 55.99
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Analysis

The two-tablet serving provides 500 mg of magnesium from dimagnesium malate and buffered TRAACS glycinate chelate. Both named forms offer better systemic potential than an oxide-led product.

The elemental total is clear, but the amount supplied by each form and the identity of the buffer are not. Five hundred milligrams may exceed what many users need from supplements once food and other products are counted.

A 120-serving bottle gives a long supply, and the formula is focused rather than crowded. Higher cost and the large serving make it best for users with a specific need rather than casual maintenance.

Who is it for
  • Adults with a substantial magnesium need
  • Users seeking malate and glycinate together
  • People comfortable with a high two-tablet serving
Best for
  • High-quality magnesium forms
  • High-dose mineral support
  • A long tablet supply

Pros

  • Uses malate and branded glycinate chelate
  • Provides 500 mg of magnesium
  • Offers 120 servings
  • Keeps the active formula focused

Cons

  • The serving may exceed routine needs
  • Form proportions are not disclosed
  • The buffering source is not identified
  • Carries a premium cost

Warnings

  • The 500 mg magnesium serving may cause diarrhea, cramping, or nausea, especially when taken at once.
  • Reduced kidney function can impair magnesium clearance, so regular supplemental use requires medical guidance in that situation.
  • Magnesium can reduce absorption of levothyroxine, bisphosphonates, and certain antibiotics; follow the medicine-specific spacing interval.

Nutrient quality

84 Highest impact

Form quality is favorable and the magnesium amount is meaningful. A high serving raises digestive-tolerance concerns for general use.

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Ingredient transparency

74 High impact

The total amount is listed, but the contribution from each form remains unclear. Complete directions and inactive ingredients are not supplied.

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Customer satisfaction

62 Moderate impact

The average customer rating is very strong. A modest rating base limits confidence in the average, while specific review experiences were not supplied.

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Value for money

79 High impact

Serving economics are reasonable for the supplied amount. Form or label limitations keep value moderate.

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Report analysis

Goals

General Health
Impact
Highest effect
A Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Magnesium · 500 mg

A clearly stated magnesium amount provides focused support for muscle, nerve, and energy-related functions. Malate and a buffered glycinate chelate offer useful absorption potential.

The serving is substantial and may be harder to tolerate for people sensitive to supplemental magnesium. Its narrow scope is appropriate for targeted foundational mineral support rather than broad nutrient coverage.

Study evidence
Magnesium Supportive 114 studies
Heart Health
Impact
Highest effect
A- Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Magnesium · 500 mg

A substantial magnesium serving uses malate and chelated glycinate forms to support heart rhythm and vascular tone. The amount is clearly disclosed and exceeds the rubric’s meaningful-dose example.

The serving may be excessive for sensitive users and does not cover lipids or cardiac mitochondrial energy. It is a focused mineral product rather than a comprehensive cardiovascular formula.

Study evidence
Magnesium Supportive 158 studies
Stress Relief
Impact
Highest effect
A- Goal FitA Strength of SupportD+ CoverageA+ Formula Quality
Magnesium · 500 mg

A substantial magnesium amount supports normal nervous-system function and stress-related metabolic resilience. Malate and glycinate chelate provide generally favorable absorption potential.

The 500 mg amount may be more than some sensitive users tolerate comfortably. The formula addresses one foundational mineral pathway rather than adaptogenic or neurotransmitter mechanisms.

Study evidence
Magnesium Supportive 13 studies
Cardiovascular Support
Impact
Highest effect
B+ Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Magnesium · 500 mg

A high magnesium amount provides focused support for vascular tone and normal cardiac electrical signaling. The formula is narrow but substantial within its mineral pathway.

Malate and buffered glycinate chelate are well-chosen forms with a clearly stated elemental amount. The 500 mg serving may cause diarrhea or abdominal discomfort and may be excessive alongside other magnesium supplements.

Study evidence
Magnesium Supportive 123 studies
Energy
Impact
Highest effect
B+ Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Magnesium · 500 mg

Magnesium at 500 mg from malate and buffered glycinate chelate offers strong support for energy metabolism when intake is inadequate. The forms and elemental amount are clearly identified.

The serving is above what many users need from a supplement and may cause loose stools or abdominal discomfort. The single-mineral design is focused but does not cover alertness or stress-resilience pathways.

Study evidence
Magnesium Supportive 4 studies
Bone Health
Impact
High effect
B- Goal FitA- Strength of SupportD+ CoverageA- Formula Quality
Magnesium · 500 mg

Magnesium directly supports bone mineral structure and vitamin D activation. The serving provides a substantial amount through malate and branded glycinate-chelate sources.

Form quality and disclosure are strong, although the dose may be less comfortable for sensitive users. The lean formula has good depth for magnesium but does not supply calcium, vitamin D, vitamin K, or matrix support.

Study evidence
Magnesium Supportive 48 studies

Ingredients

IngredientAmount per serving
Magnesium (DiMagnesium Malate, TRAACS Magnesium Glycinate Chelate buffered)
500 mg
Gluten Free Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyB- Value

malate and buffered TRAACS glycinate chelate provides useful absorption potential. The 500 mg amount is clear but may be less comfortable for sensitive users. The above-median serving cost is partly justified by the TRAACS chelated material.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  2. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  3. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  4. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  5. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  6. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  7. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  8. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  9. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  10. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  11. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  12. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  13. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  14. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  15. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  16. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  17. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  18. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  19. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  20. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  21. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  22. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  23. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  24. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  25. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  26. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  27. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  28. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  29. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  30. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  31. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  32. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  33. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  34. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  35. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  36. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  37. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium